| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Idarubicin (hydrochloride)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS6 | ribosomal protein S6 | 0.0895814 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0624671 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0617305 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0567048 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0553837 |
| RPS2 | ribosomal protein S2 | 0.0494559 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0463746 |
| BRD2 | bromodomain containing 2 | 0.0426444 |
| RPS12 | ribosomal protein S12 | 0.0424745 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0405928 |
| PCBP2 | poly(rC) binding protein 2 | 0.0400334 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.037594 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0375807 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0365549 |
| BRD4 | bromodomain containing 4 | 0.0355325 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0355079 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0349064 |
| ATF3 | activating transcription factor 3 | 0.0345511 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0338383 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0327436 |
| CCNL1 | cyclin L1 | 0.0308763 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0302561 |
| TPI1 | triosephosphate isomerase 1 | 0.0301024 |
| JUN | jun proto-oncogene | 0.0294969 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0294579 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0288983 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0280797 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0264321 |
| TPM3 | tropomyosin 3 | 0.0259795 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0258384 |
| KYNU | kynureninase | 0.0258335 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0252032 |
| YBX3 | Y box binding protein 3 | 0.0245865 |
| GPHN | gephyrin | 0.0241959 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0241917 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0236419 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0222812 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0218892 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0216812 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0216249 |
| ASF1B | anti-silencing function 1B histone chaperone | 0.0216088 |
| NTN4 | netrin 4 | 0.0209471 |
| IL6 | interleukin 6 | 0.020913 |
| IL32 | interleukin 32 | 0.0208577 |
| SIK3 | SIK family kinase 3 | 0.0205267 |
| LITAF | lipopolysaccharide-induced TNF factor | 0.0202599 |
| H2AC6 | H2A clustered histone 6 | 0.0201371 |
| STEAP4 | STEAP family member 4 | 0.0199505 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.01989 |
| DDX24 | DEAD (Asp-Glu-Ala-Asp) box helicase 24 | 0.0198775 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0196604 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0192515 |
| CREBRF | CREB3 regulatory factor | 0.0191943 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0190657 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.018891 |
| VMP1 | vacuole membrane protein 1 | 0.0183603 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0183176 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.018293 |
| RPL21 | ribosomal protein L21 | 0.0179654 |
| CFB | complement factor B | 0.0179061 |
| RPL4 | ribosomal protein L4 | 0.0178072 |
| MB21D2 | Mab-21 domain containing 2 | 0.017759 |
| SLC49A4 | solute carrier family 49 member 4 | 0.0174742 |
| HLA-A | major histocompatibility complex, class I, A | 0.0173417 |
| SYAP1 | synapse associated protein 1 | 0.0171589 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0166823 |
| RBM39 | RNA binding motif protein 39 | 0.0163177 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0160752 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0159808 |
| TJP1 | tight junction protein 1 | 0.0158892 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0158395 |
| UNK | unkempt family zinc finger | 0.0158066 |
| LSR | lipolysis stimulated lipoprotein receptor | 0.0156349 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0156136 |
| SMIM14 | small integral membrane protein 14 | 0.0155071 |
| RND3 | Rho family GTPase 3 | 0.0152646 |
| KLHL29 | kelch-like family member 29 | 0.0152274 |
| PNN | pinin, desmosome associated protein | 0.0151234 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.015093 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0150266 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0149868 |
| NOP56 | NOP56 ribonucleoprotein | 0.0149429 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | 0.0147991 |
| LCN2 | lipocalin 2 | 0.0147403 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | 0.0146646 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0146625 |
| RPS27 | ribosomal protein S27 | 0.0145418 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0145375 |
| RPL28 | ribosomal protein L28 | 0.0143103 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0142575 |
| RPS18 | ribosomal protein S18 | 0.0142316 |
| TLN1 | talin 1 | 0.0142205 |
| KLRD1 | killer cell lectin-like receptor subfamily D, member 1 | 0.0140969 |
| KRT17 | keratin 17, type I | 0.01406 |
| RPL10A | ribosomal protein L10a | 0.01397 |
| RPS17 | ribosomal protein S17 | 0.013871 |
| RPS7 | ribosomal protein S7 | 0.0138588 |
| DSPP | dentin sialophosphoprotein | 0.0138203 |
| PAPOLA | poly(A) polymerase alpha | 0.0138188 |
| KIF5B | kinesin family member 5B | 0.0137903 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB4X | thymosin beta 4, X-linked | -0.143904 |
| EMP1 | epithelial membrane protein 1 | -0.133628 |
| KRT19 | keratin 19, type I | -0.133373 |
| TMSB10 | thymosin beta 10 | -0.131268 |
| ANXA2 | annexin A2 | -0.125218 |
| PTMA | prothymosin, alpha | -0.117061 |
| HMGA1 | high mobility group AT-hook 1 | -0.110428 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.108735 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.105231 |
| LAMA4 | laminin, alpha 4 | -0.100156 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0991739 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0955175 |
| TPM4 | tropomyosin 4 | -0.0953201 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.094325 |
| ACTG1 | actin gamma 1 | -0.0940978 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0918406 |
| LDHA | lactate dehydrogenase A | -0.0917304 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0907847 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0875073 |
| RPL35A | ribosomal protein L35a | -0.0810845 |
| CD44 | CD44 molecule (Indian blood group) | -0.0796401 |
| AHNAK | AHNAK nucleoprotein | -0.0781947 |
| KRT18 | keratin 18, type I | -0.0709411 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0705896 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0685248 |
| NDRG1 | N-myc downstream regulated 1 | -0.0674333 |
| MT2A | metallothionein 2A | -0.0670835 |
| MUC4 | mucin 4, cell surface associated | -0.0656419 |
| PGK1 | phosphoglycerate kinase 1 | -0.0644504 |
| KRT7 | keratin 7, type II | -0.0640143 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0633716 |
| POTEF | POTE ankyrin domain family, member F | -0.0615226 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0612311 |
| CD2AP | CD2-associated protein | -0.0593895 |
| ACTN4 | actinin, alpha 4 | -0.0567402 |
| ERBIN | erbb2 interacting protein | -0.0563273 |
| SVIL | supervillin | -0.0556254 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0549297 |
| RUNX1 | runt-related transcription factor 1 | -0.0540531 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0533088 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0529097 |
| LAMC2 | laminin, gamma 2 | -0.0527833 |
| TMEM123 | transmembrane protein 123 | -0.0526969 |
| DSG2 | desmoglein 2 | -0.0512695 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | -0.0510686 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0507528 |
| FN1 | fibronectin 1 | -0.0507136 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.050646 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0506151 |
| NAV2 | neuron navigator 2 | -0.0501935 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0499212 |
| INTS6 | integrator complex subunit 6 | -0.0497869 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0497538 |
| ASPH | aspartate beta-hydroxylase | -0.0491346 |
| FLNB | filamin B, beta | -0.0487678 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0484902 |
| RPLP1 | ribosomal protein, large, P1 | -0.0476456 |
| RPS24 | ribosomal protein S24 | -0.0473874 |
| AFDN | afadin, adherens junction formation factor | -0.0472771 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.047274 |
| CD47 | CD47 molecule | -0.046989 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0467382 |
| MYO6 | myosin VI | -0.0466539 |
| S100A6 | S100 calcium binding protein A6 | -0.0465712 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0464085 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0461105 |
| MYOF | myoferlin | -0.0433664 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0430997 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.042478 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0423417 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0412947 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0410554 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.040573 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0397341 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0395941 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0393879 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0388586 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0388108 |
| KRT8 | keratin 8, type II | -0.0387093 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0381916 |
| MEF2A | myocyte enhancer factor 2A | -0.0370065 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.03665 |
| ANLN | anillin, actin binding protein | -0.0363536 |
| EGFR | epidermal growth factor receptor | -0.03586 |
| CDCP1 | CUB domain containing protein 1 | -0.0357988 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0356822 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0349161 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0344347 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.034169 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0341582 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0338744 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0337804 |
| SULF2 | sulfatase 2 | -0.0335032 |
| S100A9 | S100 calcium binding protein A9 | -0.0329484 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0324467 |
| ARHGAP18 | Rho GTPase activating protein 18 | -0.0323535 |
| S100A10 | S100 calcium binding protein A10 | -0.0323051 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0319924 |
| RPL23 | ribosomal protein L23 | -0.0317124 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0315972 |
