| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Idarubicin (hydrochloride)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.0794072 |
| STC1 | stanniocalcin 1 | 0.0757733 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0706752 |
| FTL | ferritin, light polypeptide | 0.0670454 |
| HLA-B | major histocompatibility complex, class I, B | 0.0622214 |
| VIM | vimentin | 0.0524411 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0505438 |
| RPS6 | ribosomal protein S6 | 0.0503621 |
| MMP2 | matrix metallopeptidase 2 | 0.0494414 |
| EGR1 | early growth response 1 | 0.0457442 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0445597 |
| HLA-A | major histocompatibility complex, class I, A | 0.0422396 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0406632 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0400221 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.03943 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0376596 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0365094 |
| B2M | beta-2-microglobulin | 0.0364372 |
| HMGA2 | high mobility group AT-hook 2 | 0.0357367 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0349509 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.0334952 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0331726 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0309305 |
| GNAS | GNAS complex locus | 0.0285017 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0280277 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0274066 |
| JUN | jun proto-oncogene | 0.0258265 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0255261 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0254602 |
| HIP1 | huntingtin interacting protein 1 | 0.0250703 |
| SMAD3 | SMAD family member 3 | 0.0238003 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0235312 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0233425 |
| RTN4 | reticulon 4 | 0.0232637 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0230831 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0222968 |
| RPL4 | ribosomal protein L4 | 0.0217941 |
| MTSS1 | metastasis suppressor 1 | 0.0216714 |
| RND3 | Rho family GTPase 3 | 0.0214603 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0208907 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0208082 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0207225 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0206577 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0203472 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0200603 |
| RPL35A | ribosomal protein L35a | 0.0194468 |
| RAI14 | retinoic acid induced 14 | 0.0192142 |
| HLA-E | major histocompatibility complex, class I, E | 0.0187448 |
| MYO9B | myosin IXB | 0.0187364 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0183293 |
| PRRC2C | proline-rich coiled-coil 2C | 0.017997 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0177915 |
| CAVIN1 | caveolae associated protein 1 | 0.0177621 |
| MYADM | myeloid-associated differentiation marker | 0.0176802 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0176278 |
| TGFB1 | transforming growth factor, beta 1 | 0.0175256 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0173453 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0169781 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0168618 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0167625 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0167349 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0164589 |
| EPHA4 | EPH receptor A4 | 0.0162293 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0161672 |
| MLPH | melanophilin | 0.0158708 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0155589 |
| EFNA5 | ephrin-A5 | 0.0154621 |
| FAT1 | FAT atypical cadherin 1 | 0.0154236 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0153192 |
| RPL36 | ribosomal protein L36 | 0.0149574 |
| ATF4 | activating transcription factor 4 | 0.0149296 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.014891 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0148758 |
| TMEM181 | transmembrane protein 181 | 0.0144985 |
| BZW2 | basic leucine zipper and W2 domains 2 | 0.0143755 |
| TPM3 | tropomyosin 3 | 0.0138899 |
| SVIL | supervillin | 0.0137588 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0137158 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0136336 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0136331 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0134315 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0133874 |
| COL3A1 | collagen, type III, alpha 1 | 0.0133547 |
| LYST | lysosomal trafficking regulator | 0.0133076 |
| STARD9 | StAR-related lipid transfer (START) domain containing 9 | 0.0131781 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0131393 |
| BPTF | bromodomain PHD finger transcription factor | 0.0131353 |
| ACYP2 | acylphosphatase 2, muscle type | 0.0130287 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0129913 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0129851 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | 0.0129313 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.012916 |
| CD68 | CD68 molecule | 0.0128464 |
| CD99 | CD99 molecule | 0.0128349 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0126498 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.0125525 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.012457 |
| AEBP1 | AE binding protein 1 | 0.0121733 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0121111 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0120825 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.418809 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.149104 |
| NDRG1 | N-myc downstream regulated 1 | -0.138427 |
| FNDC3B | fibronectin type III domain containing 3B | -0.134487 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.116022 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0933987 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0883229 |
| CDH13 | cadherin 13 | -0.0867927 |
| PGK1 | phosphoglycerate kinase 1 | -0.0810937 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0732378 |
| PKM | pyruvate kinase, muscle | -0.0687781 |
| POTEF | POTE ankyrin domain family, member F | -0.0649535 |
| FRMD4A | FERM domain containing 4A | -0.0648987 |
| ZNF292 | zinc finger protein 292 | -0.0576669 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0575643 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0572331 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0572182 |
| ASPH | aspartate beta-hydroxylase | -0.0567639 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0559116 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0533925 |
| VEGFA | vascular endothelial growth factor A | -0.0527899 |
| CENPF | centromere protein F, 350/400kDa | -0.0465684 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | -0.0463984 |
| LDHA | lactate dehydrogenase A | -0.0462859 |
| SETD5 | SET domain containing 5 | -0.0461955 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0452289 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0438258 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0434407 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0433775 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0433398 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0424893 |
| TNS3 | tensin 3 | -0.0424573 |
| COL5A1 | collagen, type V, alpha 1 | -0.0417591 |
| EGFR | epidermal growth factor receptor | -0.0409309 |
| TPM1 | tropomyosin 1 (alpha) | -0.0401772 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0401698 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0401617 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0384944 |
| COPA | coatomer protein complex, subunit alpha | -0.0376348 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0373133 |
| FAM20C | family with sequence similarity 20, member C | -0.0371743 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0370536 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0368495 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0368307 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0361128 |
| ENO1 | enolase 1, (alpha) | -0.035444 |
| PTK2 | protein tyrosine kinase 2 | -0.0350471 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0348377 |
| HDLBP | high density lipoprotein binding protein | -0.034647 |
| CD44 | CD44 molecule (Indian blood group) | -0.0344064 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0340763 |
| ATXN1 | ataxin 1 | -0.0338324 |
| HDAC9 | histone deacetylase 9 | -0.0326409 |
| ANLN | anillin, actin binding protein | -0.0325241 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0324929 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0318571 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0317879 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0316779 |
| DST | dystonin | -0.0315518 |
| CLTC | clathrin, heavy chain (Hc) | -0.0314506 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0313687 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0311845 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0311717 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0309947 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0308856 |
| USP34 | ubiquitin specific peptidase 34 | -0.0307416 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0305507 |
| NBAS | neuroblastoma amplified sequence | -0.030524 |
| SFPQ | splicing factor proline/glutamine-rich | -0.029828 |
| CANX | calnexin | -0.0295056 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0292381 |
| FKBP1A | FK506 binding protein 1A, 12kDa | -0.0291964 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0291247 |
| MSN | moesin | -0.0284055 |
| CALD1 | caldesmon 1 | -0.0283929 |
| MYOF | myoferlin | -0.0282772 |
| ARF4 | ADP-ribosylation factor 4 | -0.0276962 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0276595 |
| SEC24D | SEC24 family member D | -0.027626 |
| MT2A | metallothionein 2A | -0.0273195 |
| NREP | neuronal regeneration related protein | -0.0272649 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0270404 |
| RUNX1 | runt-related transcription factor 1 | -0.0269516 |
| XPO1 | exportin 1 | -0.0266601 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | -0.0266235 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0265881 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0265581 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.026379 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0262568 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0261775 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0261382 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0261377 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0260382 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0259728 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0255713 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0255461 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0255062 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0254338 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0253921 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0253145 |
