| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Idarubicin (hydrochloride)_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0634185 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0585602 |
| KIF26B | kinesin family member 26B | 0.0522701 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0510959 |
| MX2 | MX dynamin-like GTPase 2 | 0.048943 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0485194 |
| RNF213 | ring finger protein 213 | 0.0481098 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0472934 |
| VGF | VGF nerve growth factor inducible | 0.045787 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0414155 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0410476 |
| SNTG1 | syntrophin, gamma 1 | 0.0405632 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0394084 |
| STC1 | stanniocalcin 1 | 0.0367616 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0356934 |
| ASPH | aspartate beta-hydroxylase | 0.0352639 |
| KCNB2 | potassium channel, voltage gated Shab related subfamily B, member 2 | 0.0335734 |
| GPC5 | glypican 5 | 0.0326674 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0312769 |
| EXT1 | exostosin glycosyltransferase 1 | 0.030931 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0307782 |
| ZFHX3 | zinc finger homeobox 3 | 0.0306765 |
| SCFD2 | sec1 family domain containing 2 | 0.0302637 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like | 0.0301155 |
| KCNJ6 | potassium channel, inwardly rectifying subfamily J, member 6 | 0.0297304 |
| NRG1 | neuregulin 1 | 0.0295375 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0294073 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0290947 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0288046 |
| RIGI | RNA sensor RIG-I | 0.0287625 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.0286734 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0286719 |
| GSE1 | Gse1 coiled-coil protein | 0.0286193 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0278571 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0278049 |
| DENND4A | DENN/MADD domain containing 4A | 0.0260197 |
| PTCHD4 | patched domain containing 4 | 0.0258 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0255848 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.025142 |
| SP100 | SP100 nuclear antigen | 0.0250084 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0244584 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0243851 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0238888 |
| COL22A1 | collagen, type XXII, alpha 1 | 0.0236191 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0232717 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 | 0.0230992 |
| ST18 | suppression of tumorigenicity 18, zinc finger | 0.023016 |
| DOCK3 | dedicator of cytokinesis 3 | 0.022682 |
| PMP22 | peripheral myelin protein 22 | 0.0223785 |
| EGFR | epidermal growth factor receptor | 0.022298 |
| PLSCR1 | phospholipid scramblase 1 | 0.0218403 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0215197 |
| SMYD3 | SET and MYND domain containing 3 | 0.0213961 |
| MACROD2 | MACRO domain containing 2 | 0.0209663 |
| CUX1 | cut-like homeobox 1 | 0.0208887 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.02069 |
| ZSWIM5 | zinc finger, SWIM-type containing 5 | 0.0202402 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0201567 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0200923 |
| FAM120B | family with sequence similarity 120B | 0.020054 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0194575 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0192916 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0192861 |
| ADAR | adenosine deaminase, RNA-specific | 0.0191859 |
| GOLGB1 | golgin B1 | 0.0191834 |
| VAV2 | vav 2 guanine nucleotide exchange factor | 0.0191585 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0190675 |
| CDK13 | cyclin-dependent kinase 13 | 0.0190612 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0190479 |
| GOSR2 | golgi SNAP receptor complex member 2 | 0.0190319 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 | 0.0189282 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0188307 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | 0.0187841 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0187552 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0187155 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0186017 |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L | 0.0185273 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | 0.0185214 |
| PRKCE | protein kinase C, epsilon | 0.0183173 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0182735 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | 0.0180649 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0179695 |
| MCL1 | myeloid cell leukemia 1 | 0.0178722 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0178264 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.0177447 |
| PLXNA2 | plexin A2 | 0.0176624 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0175166 |
| ASIC2 | acid sensing (proton gated) ion channel 2 | 0.0174779 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0174421 |
| GPATCH2L | G patch domain containing 2-like | 0.017422 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0173289 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0171747 |
| AP3B2 | adaptor-related protein complex 3, beta 2 subunit | 0.0170203 |
| MYT1L | myelin transcription factor 1-like | 0.0169449 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.0168836 |
| NAV1 | neuron navigator 1 | 0.0168809 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | 0.0167639 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0166066 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0165556 |
| RPS2 | ribosomal protein S2 | 0.0164184 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE10A | phosphodiesterase 10A | -0.25907 |
| TENM1 | teneurin transmembrane protein 1 | -0.255112 |
| PTMA | prothymosin, alpha | -0.199401 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.168084 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.150068 |
| CENPF | centromere protein F, 350/400kDa | -0.133134 |
| PEG10 | paternally expressed 10 | -0.125402 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.111784 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0887053 |
| CALCA | calcitonin-related polypeptide alpha | -0.0863699 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.0777238 |
| ENO1 | enolase 1, (alpha) | -0.0772601 |
| ZNF292 | zinc finger protein 292 | -0.0767898 |
| CPE | carboxypeptidase E | -0.0765875 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0716076 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0660301 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0635515 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0624967 |
| FTL | ferritin, light polypeptide | -0.0624258 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0608673 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0573831 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0554028 |
| CA8 | carbonic anhydrase VIII | -0.0552864 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | -0.0537921 |
| PGK1 | phosphoglycerate kinase 1 | -0.0522792 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0518033 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0492468 |
| PKM | pyruvate kinase, muscle | -0.0490224 |
| MKI67 | marker of proliferation Ki-67 | -0.0484874 |
| MAP1B | microtubule-associated protein 1B | -0.0483463 |
| WDR45B | WD repeat domain 45B | -0.0481972 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0468422 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0459366 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0455402 |
| PCM1 | pericentriolar material 1 | -0.0448421 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0448405 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0444242 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0435548 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0431286 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0430823 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0425955 |
| CADM1 | cell adhesion molecule 1 | -0.0424978 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0416175 |
| CCDC88A | coiled-coil domain containing 88A | -0.0411338 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0406258 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0404421 |
| FAM162A | family with sequence similarity 162, member A | -0.040206 |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 | -0.039267 |
| NFIA | nuclear factor I/A | -0.0392641 |
| SYT1 | synaptotagmin I | -0.0388401 |
| HMGB2 | high mobility group box 2 | -0.0387894 |
| SYT4 | synaptotagmin IV | -0.0387519 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0384498 |
| NLGN1 | neuroligin 1 | -0.0381 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0374977 |
| NUF2 | NUF2, NDC80 kinetochore complex component | -0.0374638 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0371646 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0366255 |
| TPX2 | TPX2, microtubule-associated | -0.0363452 |
| ECT2 | epithelial cell transforming 2 | -0.036309 |
| IRS2 | insulin receptor substrate 2 | -0.0362234 |
| YBX1 | Y box binding protein 1 | -0.0360793 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0358378 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0358358 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0356138 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0353759 |
| DTNA | dystrobrevin, alpha | -0.0349955 |
| SGO2 | shugoshin 2 | -0.0348415 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0347715 |
| LDHA | lactate dehydrogenase A | -0.0347044 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0345192 |
| GAS2L3 | growth arrest-specific 2 like 3 | -0.0344441 |
| MATR3 | matrin 3 | -0.0338841 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0329674 |
| FAT1 | FAT atypical cadherin 1 | -0.0326278 |
| POTEF | POTE ankyrin domain family, member F | -0.0321007 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0317933 |
| CDCA2 | cell division cycle associated 2 | -0.0316608 |
| RTN4 | reticulon 4 | -0.0315737 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0314422 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0312806 |
| NRXN1 | neurexin 1 | -0.0310866 |
| PBK | PDZ binding kinase | -0.0309432 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0307973 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0306024 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0305767 |
| SEPTIN7 | septin 7 | -0.0305128 |
| KNL1 | kinetochore scaffold 1 | -0.0304023 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0303251 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0303089 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0302837 |
| JAM3 | junctional adhesion molecule 3 | -0.0302038 |
| TUBB | tubulin, beta class I | -0.0301484 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | -0.0300863 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0299553 |
| S100A9 | S100 calcium binding protein A9 | -0.0299503 |
| RPLP1 | ribosomal protein, large, P1 | -0.0294842 |
| RLF | rearranged L-myc fusion | -0.0293765 |
| PRC1 | protein regulator of cytokinesis 1 | -0.0292196 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0291578 |
