| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Idarubicin (hydrochloride)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.14075 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0681407 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0632266 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0582703 |
| HDAC9 | histone deacetylase 9 | 0.0435851 |
| MSN | moesin | 0.037406 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0329722 |
| TPM3 | tropomyosin 3 | 0.0288377 |
| SMAD3 | SMAD family member 3 | 0.0282725 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0279924 |
| RTN4 | reticulon 4 | 0.0279893 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0264725 |
| ANGPTL4 | angiopoietin-like 4 | 0.0250166 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0248202 |
| FLNA | filamin A, alpha | 0.0236873 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0228228 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0225809 |
| PRRC2C | proline-rich coiled-coil 2C | 0.021487 |
| BCL6 | B-cell CLL/lymphoma 6 | 0.0208753 |
| PCBP3 | poly(rC) binding protein 3 | 0.0203819 |
| CALD1 | caldesmon 1 | 0.0203809 |
| ZNF608 | zinc finger protein 608 | 0.0196762 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0196286 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0193391 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0192669 |
| GRID2 | glutamate receptor, ionotropic, delta 2 | 0.0190156 |
| CTSB | cathepsin B | 0.0189911 |
| GOLGB1 | golgin B1 | 0.0186191 |
| NOTCH2 | notch 2 | 0.0184002 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0181792 |
| CCNL1 | cyclin L1 | 0.0178218 |
| SVIL | supervillin | 0.0176422 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.017452 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0173711 |
| NBPF15 | neuroblastoma breakpoint family, member 15 | 0.0172648 |
| RANGAP1 | Ran GTPase activating protein 1 | 0.0168831 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0167909 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0167349 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.016475 |
| PTK2 | protein tyrosine kinase 2 | 0.0163836 |
| BPTF | bromodomain PHD finger transcription factor | 0.0161178 |
| FAM3C | family with sequence similarity 3, member C | 0.0160942 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0159434 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 0.0158018 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0155261 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0153591 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0152398 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0151585 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0149209 |
| CEP128 | centrosomal protein 128kDa | 0.0148341 |
| FBXO32 | F-box protein 32 | 0.0148134 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0147655 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.014701 |
| YBX3 | Y box binding protein 3 | 0.0146767 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0146447 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0145613 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0145093 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0144249 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0143606 |
| TUT7 | terminal uridylyl transferase 7 | 0.0142435 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0142343 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0142266 |
| AEBP1 | AE binding protein 1 | 0.0136326 |
| MELTF | melanotransferrin | 0.0134998 |
| EHBP1 | EH domain binding protein 1 | 0.0134491 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0132962 |
| ETV6 | ets variant 6 | 0.0132885 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0132401 |
| JMJD1C | jumonji domain containing 1C | 0.0131131 |
| DDX24 | DEAD (Asp-Glu-Ala-Asp) box helicase 24 | 0.0128843 |
| IL6R | interleukin 6 receptor | 0.0127888 |
| RNF24 | ring finger protein 24 | 0.0127767 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0126881 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.012683 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0125894 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0125663 |
| YTHDC1 | YTH domain containing 1 | 0.0124452 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0122458 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0122213 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0122097 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.012172 |
| DHFR | dihydrofolate reductase | 0.0121507 |
| IGF2 | insulin-like growth factor 2 | 0.0118811 |
| SEPTIN10 | septin 10 | 0.0118536 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0117612 |
| FAM219A | family with sequence similarity 219, member A | 0.0117226 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0116747 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0115078 |
| RBM39 | RNA binding motif protein 39 | 0.0114967 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0114767 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0114533 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.011383 |
| OSMR | oncostatin M receptor | 0.0112822 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0111891 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0110775 |
| KDM5A | lysine (K)-specific demethylase 5A | 0.0110556 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0110416 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.011017 |
| TSG101 | tumor susceptibility 101 | 0.0109786 |
| MLXIP | MLX interacting protein | 0.0108878 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.256219 |
| NLGN1 | neuroligin 1 | -0.163382 |
| NRG3 | neuregulin 3 | -0.151316 |
| VIM | vimentin | -0.145584 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.141086 |
| LSAMP | limbic system-associated membrane protein | -0.127098 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.122611 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.103337 |
| FMN1 | formin 1 | -0.101284 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0962121 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.079038 |
| RPL35A | ribosomal protein L35a | -0.0701396 |
| SQSTM1 | sequestosome 1 | -0.0679715 |
| PTMA | prothymosin, alpha | -0.0644186 |
| FTL | ferritin, light polypeptide | -0.0627856 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0626157 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0616118 |
| RPL23 | ribosomal protein L23 | -0.0552487 |
| TMSB10 | thymosin beta 10 | -0.0549318 |
| RPS3 | ribosomal protein S3 | -0.0542206 |
| PGK1 | phosphoglycerate kinase 1 | -0.0531372 |
| LDHA | lactate dehydrogenase A | -0.0526893 |
| RPLP1 | ribosomal protein, large, P1 | -0.052361 |
| MT2A | metallothionein 2A | -0.0518511 |
| PMEL | premelanosome protein | -0.0512618 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0496315 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0481928 |
| FRMD4A | FERM domain containing 4A | -0.0470497 |
| MSI2 | musashi RNA-binding protein 2 | -0.0461354 |
| RPL31 | ribosomal protein L31 | -0.0443171 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.043966 |
| PRELID2 | PRELI domain containing 2 | -0.0437884 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0426988 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0426469 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0423474 |
| RPS24 | ribosomal protein S24 | -0.042187 |
| TENM1 | teneurin transmembrane protein 1 | -0.0408093 |
| IGF1R | insulin-like growth factor 1 receptor | -0.040324 |
| RPL38 | ribosomal protein L38 | -0.0394382 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0386978 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | -0.0382094 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0381043 |
| CCND1 | cyclin D1 | -0.0374914 |
| RPL11 | ribosomal protein L11 | -0.0373538 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0372589 |
| SMYD3 | SET and MYND domain containing 3 | -0.0372568 |
| CANX | calnexin | -0.0365722 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0364283 |
| FHIT | fragile histidine triad | -0.036274 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0358482 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.0356433 |
| KAZN | kazrin, periplakin interacting protein | -0.0356256 |
| ACTG1 | actin gamma 1 | -0.0351644 |
| RPS23 | ribosomal protein S23 | -0.0347526 |
| RPL12 | ribosomal protein L12 | -0.0334984 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0334511 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0329433 |
| TNNC1 | troponin C type 1 (slow) | -0.0328314 |
| SBF2 | SET binding factor 2 | -0.0326685 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.0326184 |
| ASPH | aspartate beta-hydroxylase | -0.0319562 |
| CA8 | carbonic anhydrase VIII | -0.0314856 |
| HMGA1 | high mobility group AT-hook 1 | -0.0314765 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | -0.0308011 |
| FMNL2 | formin-like 2 | -0.0307287 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0303923 |
| RPS21 | ribosomal protein S21 | -0.0298473 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | -0.0296689 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0295672 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0294981 |
| CTTN | cortactin | -0.0292661 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0292283 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0290824 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0287334 |
| CFAP20DC | CFAP20 domain containing | -0.0286801 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0286345 |
| INTS6 | integrator complex subunit 6 | -0.0285784 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0285314 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0283723 |
| PDE10A | phosphodiesterase 10A | -0.0281198 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0280569 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0277905 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0274932 |
| PKM | pyruvate kinase, muscle | -0.0273367 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0271729 |
| RPL34 | ribosomal protein L34 | -0.0269624 |
| RPS8 | ribosomal protein S8 | -0.0268132 |
| MARCHF1 | membrane associated ring-CH-type finger 1 | -0.026813 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0267293 |
| RPLP2 | ribosomal protein, large, P2 | -0.0266482 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0266232 |
| RPL27A | ribosomal protein L27a | -0.0266034 |
| RNF213 | ring finger protein 213 | -0.0265045 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0264426 |
| UPP1 | uridine phosphorylase 1 | -0.02622 |
| KIAA1549L | KIAA1549-like | -0.0259474 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.025687 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0255412 |
| IER3 | immediate early response 3 | -0.02545 |
| RPL19 | ribosomal protein L19 | -0.0252743 |
