| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Idarubicin (hydrochloride)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS6 | ribosomal protein S6 | 0.0725775 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0637153 |
| RTN4 | reticulon 4 | 0.0512438 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0499897 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0485042 |
| TXNRD1 | thioredoxin reductase 1 | 0.0439148 |
| PDGFC | platelet derived growth factor C | 0.0417735 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0394136 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0389549 |
| PFN1 | profilin 1 | 0.0379013 |
| TXNIP | thioredoxin interacting protein | 0.0375651 |
| RBM25 | RNA binding motif protein 25 | 0.0362294 |
| PCBP2 | poly(rC) binding protein 2 | 0.0352657 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0347045 |
| CCNL1 | cyclin L1 | 0.0318799 |
| PKM | pyruvate kinase, muscle | 0.0317563 |
| GOLGA4 | golgin A4 | 0.0311175 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0295383 |
| ZNF292 | zinc finger protein 292 | 0.0292544 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0283635 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0282104 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0276417 |
| RPS2 | ribosomal protein S2 | 0.0275434 |
| HMGA1 | high mobility group AT-hook 1 | 0.0274236 |
| BRD2 | bromodomain containing 2 | 0.0271994 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0264574 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0264272 |
| VMP1 | vacuole membrane protein 1 | 0.0259017 |
| MT2A | metallothionein 2A | 0.025751 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0256306 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0252314 |
| CRY1 | cryptochrome circadian clock 1 | 0.0242122 |
| RPL3 | ribosomal protein L3 | 0.0239612 |
| IGF2 | insulin-like growth factor 2 | 0.0238739 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0236125 |
| WDR43 | WD repeat domain 43 | 0.0234458 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0231975 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0231046 |
| RIOK3 | RIO kinase 3 | 0.0230534 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0229884 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0227078 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | 0.0226572 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.022626 |
| PNN | pinin, desmosome associated protein | 0.0225471 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0224955 |
| POTEF | POTE ankyrin domain family, member F | 0.0221999 |
| MATR3 | matrin 3 | 0.022199 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0221291 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.02188 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0217848 |
| LATS2 | large tumor suppressor kinase 2 | 0.0217467 |
| YBX1 | Y box binding protein 1 | 0.0215848 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0213363 |
| NUP58 | nucleoporin 58 | 0.0209152 |
| DSTN | destrin (actin depolymerizing factor) | 0.020479 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0204597 |
| YBX3 | Y box binding protein 3 | 0.0202705 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0198493 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0197642 |
| SF1 | splicing factor 1 | 0.0195578 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0195161 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0192602 |
| UBE3A | ubiquitin protein ligase E3A | 0.0189937 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0189039 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0187229 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0187104 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0187097 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0182871 |
| JMJD1C | jumonji domain containing 1C | 0.01823 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0181399 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0181354 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.0178478 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.0178299 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0176788 |
| PLK2 | polo-like kinase 2 | 0.0175623 |
| FAT1 | FAT atypical cadherin 1 | 0.0174025 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0171882 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0171672 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0171553 |
| RPS17 | ribosomal protein S17 | 0.0170086 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0169341 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0167925 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0167828 |
| RPLP2 | ribosomal protein, large, P2 | 0.0167633 |
| DHFR | dihydrofolate reductase | 0.0167173 |
| TPM3 | tropomyosin 3 | 0.016658 |
| RPL21 | ribosomal protein L21 | 0.0166297 |
| BSDC1 | BSD domain containing 1 | 0.0164517 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0163434 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0162133 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0162105 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.016197 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0161369 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0161107 |
| FTL | ferritin, light polypeptide | 0.0159774 |
| FAM168B | family with sequence similarity 168, member B | 0.015896 |
| ZFR | zinc finger RNA binding protein | 0.0157039 |
| FN1 | fibronectin 1 | 0.0156563 |
| BRD4 | bromodomain containing 4 | 0.0155434 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0153185 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.197981 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.196527 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.192908 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.178949 |
| VCL | vinculin | -0.146522 |
| AHNAK | AHNAK nucleoprotein | -0.144618 |
| BMP10 | bone morphogenetic protein 10 | -0.135127 |
| EGFR | epidermal growth factor receptor | -0.132138 |
| FOXP1 | forkhead box P1 | -0.0906329 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.085347 |
| NPAS2 | neuronal PAS domain protein 2 | -0.084456 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0841544 |
| PRELID2 | PRELI domain containing 2 | -0.0836104 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0835225 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.082002 |
| NFIA | nuclear factor I/A | -0.0791234 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0745443 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0731891 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0721725 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0706377 |
| EFNA5 | ephrin-A5 | -0.0682651 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0680416 |
| SMYD3 | SET and MYND domain containing 3 | -0.0679172 |
| TMSB4X | thymosin beta 4, X-linked | -0.0678166 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0670598 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0613873 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.061356 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0586722 |
| LDHA | lactate dehydrogenase A | -0.0576676 |
| TJP1 | tight junction protein 1 | -0.0554613 |
| NBEA | neurobeachin | -0.0553282 |
| NAV2 | neuron navigator 2 | -0.0544333 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0536293 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0518472 |
| INTS6 | integrator complex subunit 6 | -0.0518304 |
| GLI3 | GLI family zinc finger 3 | -0.0517612 |
| ECT2 | epithelial cell transforming 2 | -0.0506605 |
| DENND1A | DENN/MADD domain containing 1A | -0.0485435 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0482395 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.047927 |
| HDAC9 | histone deacetylase 9 | -0.0473891 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0446048 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0441627 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0436797 |
| ANXA1 | annexin A1 | -0.0433914 |
| MKI67 | marker of proliferation Ki-67 | -0.0430026 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0425625 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0418704 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0410169 |
| GLI2 | GLI family zinc finger 2 | -0.0408986 |
| MYO5C | myosin VC | -0.0397964 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0384531 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0380526 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0375405 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0372734 |
| CCND1 | cyclin D1 | -0.0372636 |
| CD47 | CD47 molecule | -0.0371195 |
| PGK1 | phosphoglycerate kinase 1 | -0.0366974 |
| PDE10A | phosphodiesterase 10A | -0.0362456 |
| RPL31 | ribosomal protein L31 | -0.03554 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0343834 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.034193 |
| TRERF1 | transcriptional regulating factor 1 | -0.0341817 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0339262 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0335958 |
| PDE7B | phosphodiesterase 7B | -0.0335532 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0333226 |
| CUX1 | cut-like homeobox 1 | -0.0332545 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0330445 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0330007 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0324545 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0323741 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0320823 |
| FHIT | fragile histidine triad | -0.0318202 |
| GPATCH8 | G patch domain containing 8 | -0.0317195 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0306585 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0306347 |
| ASPH | aspartate beta-hydroxylase | -0.0305155 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.0304411 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0304024 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0301236 |
| NEBL | nebulette | -0.0299222 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0296827 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0294201 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0290719 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0290199 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.02858 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0285435 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.028468 |
| CENPF | centromere protein F, 350/400kDa | -0.0284086 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0282487 |
| BCOR | BCL6 corepressor | -0.0279905 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0278573 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0278544 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0278274 |
| TMEM65 | transmembrane protein 65 | -0.0277796 |
| ENOSF1 | enolase superfamily member 1 | -0.0276646 |
| HJURP | Holliday junction recognition protein | -0.0276299 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0275573 |
| PLCE1 | phospholipase C, epsilon 1 | -0.0269836 |
