| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Idarubicin (hydrochloride)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.1435 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.119257 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.099485 |
| HMGA2 | high mobility group AT-hook 2 | 0.0975577 |
| RPS6 | ribosomal protein S6 | 0.0795166 |
| EFNA5 | ephrin-A5 | 0.079276 |
| GLIS3 | GLIS family zinc finger 3 | 0.0774859 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0642527 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0629377 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0512259 |
| CDH13 | cadherin 13 | 0.0490796 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0489046 |
| STC1 | stanniocalcin 1 | 0.0461691 |
| RPS2 | ribosomal protein S2 | 0.0446282 |
| RND3 | Rho family GTPase 3 | 0.0445236 |
| COL5A1 | collagen, type V, alpha 1 | 0.0422471 |
| MT2A | metallothionein 2A | 0.0420746 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.040795 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0405513 |
| MLPH | melanophilin | 0.0402296 |
| ASPH | aspartate beta-hydroxylase | 0.0390997 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0372405 |
| RPS12 | ribosomal protein S12 | 0.0368713 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0365506 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0357934 |
| HDAC9 | histone deacetylase 9 | 0.0351497 |
| STC2 | stanniocalcin 2 | 0.0348048 |
| TMEM132D | transmembrane protein 132D | 0.033632 |
| SMAD3 | SMAD family member 3 | 0.0335633 |
| EGR1 | early growth response 1 | 0.0334574 |
| GPC6 | glypican 6 | 0.0328763 |
| NDRG1 | N-myc downstream regulated 1 | 0.0324027 |
| CALR | calreticulin | 0.0318229 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0308853 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0306297 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0300494 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0299204 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0294337 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0292711 |
| BRD2 | bromodomain containing 2 | 0.0281654 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0279183 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0272997 |
| HLA-A | major histocompatibility complex, class I, A | 0.0261324 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0253374 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0252145 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0248084 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0246539 |
| EGFR | epidermal growth factor receptor | 0.0239006 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0238182 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.023492 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0233487 |
| MYO10 | myosin X | 0.0225455 |
| INHBA | inhibin, beta A | 0.0225368 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0222756 |
| VEGFA | vascular endothelial growth factor A | 0.0220992 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0214756 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0214335 |
| RPS8 | ribosomal protein S8 | 0.0213249 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.021305 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0210135 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0209986 |
| SAMD3 | sterile alpha motif domain containing 3 | 0.0204766 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.020462 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0197244 |
| RUNX1 | runt-related transcription factor 1 | 0.0193905 |
| LOX | lysyl oxidase | 0.0192289 |
| GOLGB1 | golgin B1 | 0.0191517 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0190024 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 0.0186735 |
| RPL10A | ribosomal protein L10a | 0.0184801 |
| RPS17 | ribosomal protein S17 | 0.0182856 |
| NAV1 | neuron navigator 1 | 0.0181591 |
| CUX1 | cut-like homeobox 1 | 0.0180433 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0179348 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0178862 |
| PCBP3 | poly(rC) binding protein 3 | 0.0178135 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0176122 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0175933 |
| TMF1 | TATA element modulatory factor 1 | 0.0173589 |
| TPM3 | tropomyosin 3 | 0.0173566 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0171257 |
| LAMB1 | laminin, beta 1 | 0.0170104 |
| RPL4 | ribosomal protein L4 | 0.0165856 |
| DHFR | dihydrofolate reductase | 0.0163644 |
| INTS6 | integrator complex subunit 6 | 0.0163622 |
| COL27A1 | collagen, type XXVII, alpha 1 | 0.0159091 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0156707 |
| WDR27 | WD repeat domain 27 | 0.0156669 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0155529 |
| IL32 | interleukin 32 | 0.0153651 |
| ATF4 | activating transcription factor 4 | 0.0153511 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) | 0.0153107 |
| CCND1 | cyclin D1 | 0.0152655 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | 0.0152237 |
| TPI1 | triosephosphate isomerase 1 | 0.0150669 |
| DTNA | dystrobrevin, alpha | 0.0147832 |
| DENND2A | DENN/MADD domain containing 2A | 0.0147387 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0146181 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0145388 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0145177 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | -0.280362 |
| FN1 | fibronectin 1 | -0.249621 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.127375 |
| PGK1 | phosphoglycerate kinase 1 | -0.108678 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.103825 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0948755 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0928949 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0891958 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0800086 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0788313 |
| FRMD4A | FERM domain containing 4A | -0.075715 |
| MYOF | myoferlin | -0.0752983 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0749487 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0734189 |
| VCL | vinculin | -0.0734049 |
| LDHA | lactate dehydrogenase A | -0.0725182 |
| SPAG9 | sperm associated antigen 9 | -0.0705214 |
| NAV2 | neuron navigator 2 | -0.0701739 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0655109 |
| TMSB10 | thymosin beta 10 | -0.0620371 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0610175 |
| WTAP | Wilms tumor 1 associated protein | -0.0609515 |
| OGA | O-GlcNAcase | -0.0601785 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0585207 |
| SBF2 | SET binding factor 2 | -0.0580423 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.055773 |
| RPS24 | ribosomal protein S24 | -0.0557132 |
| RTN4 | reticulon 4 | -0.0556689 |
| ANXA2 | annexin A2 | -0.0554473 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0549897 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0548927 |
| ZNF292 | zinc finger protein 292 | -0.0519029 |
| RIGI | RNA sensor RIG-I | -0.0515876 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0499311 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0494442 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0493609 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0490213 |
| TPM4 | tropomyosin 4 | -0.0487952 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0475953 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0448813 |
| KLF6 | Kruppel-like factor 6 | -0.0446009 |
| RBM39 | RNA binding motif protein 39 | -0.0441088 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0437648 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0430456 |
| PDE10A | phosphodiesterase 10A | -0.0426984 |
| MX1 | MX dynamin-like GTPase 1 | -0.0418587 |
| CADM1 | cell adhesion molecule 1 | -0.041368 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.040535 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0404107 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0401306 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0400963 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0400421 |
| RPL23 | ribosomal protein L23 | -0.0396502 |
| RNF213 | ring finger protein 213 | -0.0392739 |
| DEK | DEK proto-oncogene | -0.0392327 |
| FOXO3 | forkhead box O3 | -0.0390027 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0382726 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0380137 |
| TUBB | tubulin, beta class I | -0.0378724 |
| TMEM123 | transmembrane protein 123 | -0.0367447 |
| MORF4L2 | mortality factor 4 like 2 | -0.036304 |
| THBS1 | thrombospondin 1 | -0.0361711 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0358205 |
| AFDN | afadin, adherens junction formation factor | -0.0358002 |
| AHNAK | AHNAK nucleoprotein | -0.0357595 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0355788 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0355145 |
| DENND5A | DENN/MADD domain containing 5A | -0.0354927 |
| JMJD1C | jumonji domain containing 1C | -0.0348386 |
| KYNU | kynureninase | -0.03474 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0346039 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0345334 |
| DST | dystonin | -0.0344452 |
| CLIC4 | chloride intracellular channel 4 | -0.0341448 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0340976 |
| IER3 | immediate early response 3 | -0.0340265 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.0339449 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0337909 |
| NABP1 | nucleic acid binding protein 1 | -0.033362 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0327277 |
| ACTG1 | actin gamma 1 | -0.0323966 |
| TXNRD1 | thioredoxin reductase 1 | -0.0323351 |
| RPL35A | ribosomal protein L35a | -0.0321829 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0321279 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0319263 |
| RPS4X | ribosomal protein S4, X-linked | -0.031389 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0311795 |
| PALLD | palladin, cytoskeletal associated protein | -0.031153 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0309383 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0309243 |
| ANLN | anillin, actin binding protein | -0.0303019 |
| ACTN1 | actinin, alpha 1 | -0.030215 |
| SP100 | SP100 nuclear antigen | -0.0301182 |
| FRMD5 | FERM domain containing 5 | -0.0300409 |
| QKI | QKI, KH domain containing, RNA binding | -0.0299553 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0299541 |
| TPM1 | tropomyosin 1 (alpha) | -0.0299432 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0298308 |
| UBC | ubiquitin C | -0.0297239 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.029479 |
