| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Idarubicin (hydrochloride)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.1452 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.112079 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.110978 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0962478 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0829414 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0627702 |
| TLN1 | talin 1 | 0.0562967 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0558844 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0537593 |
| RPS6 | ribosomal protein S6 | 0.049414 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0483591 |
| CENPF | centromere protein F, 350/400kDa | 0.0458875 |
| IL6 | interleukin 6 | 0.045222 |
| HMGA2 | high mobility group AT-hook 2 | 0.0440111 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0432263 |
| CD44 | CD44 molecule (Indian blood group) | 0.0421579 |
| MT2A | metallothionein 2A | 0.0414359 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0409672 |
| ECE1 | endothelin converting enzyme 1 | 0.0409205 |
| COL5A1 | collagen, type V, alpha 1 | 0.0402125 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0399897 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0397629 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0385724 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0373615 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0369149 |
| TPI1 | triosephosphate isomerase 1 | 0.0363009 |
| LAMB3 | laminin, beta 3 | 0.0359976 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0348384 |
| FLNA | filamin A, alpha | 0.0342523 |
| ANKRD11 | ankyrin repeat domain 11 | 0.034181 |
| STC2 | stanniocalcin 2 | 0.0335676 |
| RUNX1 | runt-related transcription factor 1 | 0.0333812 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0333346 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0321 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0320787 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0316197 |
| RIN2 | Ras and Rab interactor 2 | 0.0309408 |
| REST | RE1-silencing transcription factor | 0.0307472 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0302918 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0300931 |
| EGR1 | early growth response 1 | 0.0295692 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0295586 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0295358 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0294745 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0286211 |
| MCFD2 | multiple coagulation factor deficiency 2 | 0.0285457 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0283084 |
| NCOR1 | nuclear receptor corepressor 1 | 0.028165 |
| MYO9B | myosin IXB | 0.0276643 |
| RPS12 | ribosomal protein S12 | 0.027646 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0268823 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0268338 |
| CALR | calreticulin | 0.0268174 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0263164 |
| EREG | epiregulin | 0.0261042 |
| PTK2 | protein tyrosine kinase 2 | 0.0260494 |
| EHBP1 | EH domain binding protein 1 | 0.0259469 |
| TMEM165 | transmembrane protein 165 | 0.0257512 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0255693 |
| ADNP | activity-dependent neuroprotector homeobox | 0.0255086 |
| YBX1 | Y box binding protein 1 | 0.0254675 |
| CTSA | cathepsin A | 0.0254208 |
| BPTF | bromodomain PHD finger transcription factor | 0.0253635 |
| MAP1B | microtubule-associated protein 1B | 0.0250928 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0250434 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0250131 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0249887 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0249274 |
| SRPK2 | SRSF protein kinase 2 | 0.0246895 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0246697 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0245398 |
| JUN | jun proto-oncogene | 0.0245353 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0243003 |
| RNF213 | ring finger protein 213 | 0.0240332 |
| SMAD3 | SMAD family member 3 | 0.0238325 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0237316 |
| MKI67 | marker of proliferation Ki-67 | 0.0236785 |
| SYAP1 | synapse associated protein 1 | 0.0235683 |
| TET2 | tet methylcytosine dioxygenase 2 | 0.0232938 |
| VEGFC | vascular endothelial growth factor C | 0.0232723 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0232579 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0231766 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | 0.0230846 |
| NCOA6 | nuclear receptor coactivator 6 | 0.022951 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0227769 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0226081 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0223672 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0223641 |
| FAM13A | family with sequence similarity 13, member A | 0.0223426 |
| RPL37A | ribosomal protein L37a | 0.0222759 |
| TRIOBP | TRIO and F-actin binding protein | 0.0222301 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0221257 |
| RPS2 | ribosomal protein S2 | 0.0219321 |
| SLC25A51 | solute carrier family 25, member 51 | 0.0218735 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0218732 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0215472 |
| CA12 | carbonic anhydrase XII | 0.0214311 |
| CLEC16A | C-type lectin domain family 16, member A | 0.0213785 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.0213305 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0212996 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | -0.29323 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.16912 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.120693 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.10173 |
| CDH13 | cadherin 13 | -0.0911988 |
| TMSB10 | thymosin beta 10 | -0.083677 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0826509 |
| MYOF | myoferlin | -0.0785108 |
| COL1A2 | collagen, type I, alpha 2 | -0.0782338 |
| HDLBP | high density lipoprotein binding protein | -0.0764953 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0731967 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0725091 |
| CALU | calumenin | -0.0714603 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0704951 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.068683 |
| COL1A1 | collagen, type I, alpha 1 | -0.0685843 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0665781 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0657513 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0620131 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0610982 |
| PRRC1 | proline-rich coiled-coil 1 | -0.058923 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.058855 |
| LDHA | lactate dehydrogenase A | -0.0584156 |
| NAV1 | neuron navigator 1 | -0.0582144 |
| FN1 | fibronectin 1 | -0.0546124 |
| PRSS23 | protease, serine, 23 | -0.0543351 |
| SEC24D | SEC24 family member D | -0.0521898 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0514328 |
| PTGES2 | prostaglandin E synthase 2 | -0.0508045 |
| VCL | vinculin | -0.0502906 |
| COPA | coatomer protein complex, subunit alpha | -0.049611 |
| ANXA2 | annexin A2 | -0.0493845 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0492265 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0491137 |
| CANX | calnexin | -0.0484668 |
| PTMA | prothymosin, alpha | -0.0477244 |
| COG5 | component of oligomeric golgi complex 5 | -0.047695 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.047368 |
| AHNAK | AHNAK nucleoprotein | -0.0473068 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0466896 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0466105 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0441416 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0438241 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0436799 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0435275 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0433809 |
| COL5A2 | collagen, type V, alpha 2 | -0.0422063 |
| RHEB | Ras homolog enriched in brain | -0.0406508 |
| ACTG1 | actin gamma 1 | -0.0406025 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0403619 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0395325 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0387808 |
| OGA | O-GlcNAcase | -0.0387778 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.038452 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.03839 |
| VIM | vimentin | -0.0381924 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0379873 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0378003 |
| ZNF292 | zinc finger protein 292 | -0.0375396 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0373366 |
| CD109 | CD109 molecule | -0.0369726 |
| MORF4L2 | mortality factor 4 like 2 | -0.036579 |
| HLA-C | major histocompatibility complex, class I, C | -0.0364548 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0362785 |
| SRP54 | signal recognition particle 54kDa | -0.0361622 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.035705 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0356932 |
| RBM39 | RNA binding motif protein 39 | -0.0353168 |
| HELZ | helicase with zinc finger | -0.0350205 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0348598 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0339893 |
| LOXL2 | lysyl oxidase-like 2 | -0.0339112 |
| MED13L | mediator complex subunit 13-like | -0.0336338 |
| SCFD2 | sec1 family domain containing 2 | -0.0336009 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0335621 |
| BSG | basigin (Ok blood group) | -0.033443 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0332171 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0331006 |
| SDC4 | syndecan 4 | -0.0328924 |
| NABP1 | nucleic acid binding protein 1 | -0.0328051 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0324318 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0323848 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0319387 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0318466 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0318321 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0317271 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0316826 |
| TFG | TRK-fused gene | -0.0316702 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0313304 |
| COG6 | component of oligomeric golgi complex 6 | -0.0309789 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.0306501 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | -0.0303708 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0302816 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.029959 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0299348 |
| RAB10 | RAB10, member RAS oncogene family | -0.0298779 |
| TMEM41B | transmembrane protein 41B | -0.029787 |
| HBP1 | HMG-box transcription factor 1 | -0.0293384 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0292065 |
| SUCO | SUN domain containing ossification factor | -0.029142 |
