| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Idarubicin (hydrochloride)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0997632 |
| GOLGA4 | golgin A4 | 0.091422 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0758256 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0698839 |
| EGR1 | early growth response 1 | 0.0698161 |
| RPS12 | ribosomal protein S12 | 0.0695945 |
| SQSTM1 | sequestosome 1 | 0.0647082 |
| YBX3 | Y box binding protein 3 | 0.059123 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0585732 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.055122 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0542026 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0541812 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0538305 |
| RBM39 | RNA binding motif protein 39 | 0.0533449 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0482729 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.047578 |
| TPI1 | triosephosphate isomerase 1 | 0.0472384 |
| TXNIP | thioredoxin interacting protein | 0.0460391 |
| HLA-B | major histocompatibility complex, class I, B | 0.0450956 |
| FUS | FUS RNA binding protein | 0.0450252 |
| CAVIN1 | caveolae associated protein 1 | 0.0427817 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0418126 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0401099 |
| SMYD3 | SET and MYND domain containing 3 | 0.0399185 |
| JMJD1C | jumonji domain containing 1C | 0.0397881 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0391366 |
| CANX | calnexin | 0.0382386 |
| H3-3B | H3.3 histone B | 0.038109 |
| IPO7 | importin 7 | 0.0376456 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0371112 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0370756 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0369694 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0365226 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0359165 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0359104 |
| HLA-C | major histocompatibility complex, class I, C | 0.0347344 |
| ATXN1L | ataxin 1-like | 0.0344208 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0338831 |
| GOLGB1 | golgin B1 | 0.0335722 |
| TPM3 | tropomyosin 3 | 0.0333316 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0328313 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0321477 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0321053 |
| B2M | beta-2-microglobulin | 0.0318703 |
| EZR | ezrin | 0.0318476 |
| DDX24 | DEAD (Asp-Glu-Ala-Asp) box helicase 24 | 0.0317637 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.031537 |
| RIOK3 | RIO kinase 3 | 0.0314242 |
| R3HDM2 | R3H domain containing 2 | 0.0313547 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.031104 |
| YAP1 | Yes-associated protein 1 | 0.0309286 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0308176 |
| BRD2 | bromodomain containing 2 | 0.0305395 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0303574 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0301234 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.0300038 |
| NOP56 | NOP56 ribonucleoprotein | 0.0298357 |
| RPL4 | ribosomal protein L4 | 0.029766 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0297497 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0292229 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0286165 |
| BRD4 | bromodomain containing 4 | 0.0285824 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | 0.0285014 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0284057 |
| RTN4 | reticulon 4 | 0.0278335 |
| TAF7 | TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa | 0.0277858 |
| RPL26 | ribosomal protein L26 | 0.0275977 |
| RNF111 | ring finger protein 111 | 0.0267475 |
| RPS8 | ribosomal protein S8 | 0.0265372 |
| SFTPA2 | surfactant protein A2 | 0.0264564 |
| ANXA5 | annexin A5 | 0.0264143 |
| JUN | jun proto-oncogene | 0.0263369 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0262952 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | 0.0262926 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0262666 |
| NOP58 | NOP58 ribonucleoprotein | 0.0260445 |
| USP53 | ubiquitin specific peptidase 53 | 0.026043 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0260202 |
| HIP1 | huntingtin interacting protein 1 | 0.0259383 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0258775 |
| CHD8 | chromodomain helicase DNA binding protein 8 | 0.0258554 |
| RBMX | RNA binding motif protein, X-linked | 0.0257133 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 | 0.0253244 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0252121 |
| DENND4A | DENN/MADD domain containing 4A | 0.0252044 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0251732 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.025115 |
| KLF10 | Kruppel-like factor 10 | 0.0248724 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.0248461 |
| FTL | ferritin, light polypeptide | 0.0248336 |
| RPS6 | ribosomal protein S6 | 0.0247403 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0246948 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0246292 |
| HLA-E | major histocompatibility complex, class I, E | 0.0245913 |
| CUL5 | cullin 5 | 0.0243152 |
| CAPRIN2 | caprin family member 2 | 0.0243115 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0242582 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | 0.0239277 |
| WWC2 | WW and C2 domain containing 2 | 0.0238769 |
| RACK1 | receptor for activated C kinase 1 | 0.0238603 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.144665 |
| LDHA | lactate dehydrogenase A | -0.130116 |
| FNDC3B | fibronectin type III domain containing 3B | -0.114339 |
| TMSB10 | thymosin beta 10 | -0.102479 |
| DNER | delta/notch-like EGF repeat containing | -0.0829661 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0824712 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0743752 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0698493 |
| PTMA | prothymosin, alpha | -0.0684961 |
| INTS6 | integrator complex subunit 6 | -0.0679139 |
| HMGA2 | high mobility group AT-hook 2 | -0.0663406 |
| CD44 | CD44 molecule (Indian blood group) | -0.0654013 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0614248 |
| POTEF | POTE ankyrin domain family, member F | -0.0612671 |
| NAV2 | neuron navigator 2 | -0.0598844 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0568151 |
| SPAG9 | sperm associated antigen 9 | -0.0555711 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0530757 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0513969 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0512012 |
| PRELID2 | PRELI domain containing 2 | -0.0509419 |
| ZNF292 | zinc finger protein 292 | -0.0485934 |
| TPM4 | tropomyosin 4 | -0.0484068 |
| CENPF | centromere protein F, 350/400kDa | -0.0474553 |
| PKM | pyruvate kinase, muscle | -0.0466558 |
| HJURP | Holliday junction recognition protein | -0.04627 |
| PTK2 | protein tyrosine kinase 2 | -0.0459513 |
| PDE8A | phosphodiesterase 8A | -0.0458845 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0452008 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0442016 |
| SETD5 | SET domain containing 5 | -0.0437029 |
| PYGL | phosphorylase, glycogen, liver | -0.0434715 |
| OSMR | oncostatin M receptor | -0.0428949 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0422155 |
| FMN1 | formin 1 | -0.0413022 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.041083 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.040907 |
| VCL | vinculin | -0.039918 |
| NBEAL1 | neurobeachin-like 1 | -0.0397533 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0391627 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0373653 |
| NALCN | sodium leak channel, non selective | -0.0372192 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | -0.0370284 |
| RAI14 | retinoic acid induced 14 | -0.0368971 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0362391 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0356831 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0355062 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0353834 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0351268 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.035012 |
| USP34 | ubiquitin specific peptidase 34 | -0.0349041 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0347597 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.034388 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | -0.0334636 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0332366 |
| SCFD1 | sec1 family domain containing 1 | -0.0321306 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0320152 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0314522 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0313369 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0311013 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0306949 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0305535 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0304955 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0303949 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -0.0296708 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0296169 |
| DIAPH3 | diaphanous-related formin 3 | -0.0293908 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | -0.0292604 |
| TPX2 | TPX2, microtubule-associated | -0.0286188 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0285528 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0285103 |
| MT2A | metallothionein 2A | -0.0280724 |
| HBS1L | HBS1-like translational GTPase | -0.0280226 |
| SGO2 | shugoshin 2 | -0.0278702 |
| PRSS23 | protease, serine, 23 | -0.0276215 |
| R3HDM1 | R3H domain containing 1 | -0.027435 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0270899 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0270215 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0269221 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0268914 |
| SBF2 | SET binding factor 2 | -0.0268644 |
| ACER3 | alkaline ceramidase 3 | -0.0267941 |
| SS18 | synovial sarcoma translocation, chromosome 18 | -0.0263833 |
| ARMH4 | armadillo like helical domain containing 4 | -0.0263352 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0262957 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0262128 |
| ATXN1 | ataxin 1 | -0.0261269 |
| NF1 | neurofibromin 1 | -0.0260989 |
| PRKCE | protein kinase C, epsilon | -0.0260569 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0260287 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0259639 |
| SMAP1 | small ArfGAP 1 | -0.0258818 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0258036 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0255 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0254013 |
| SNX14 | sorting nexin 14 | -0.025333 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0253238 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0253213 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0252225 |
| ARHGAP18 | Rho GTPase activating protein 18 | -0.0249636 |
