| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Idarubicin (hydrochloride)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNIP | thioredoxin interacting protein | 0.0568116 |
| TMEM156 | transmembrane protein 156 | 0.0543787 |
| TXNRD1 | thioredoxin reductase 1 | 0.0492251 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0423216 |
| NTN4 | netrin 4 | 0.0391757 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0348501 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0343105 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0338381 |
| EGFR | epidermal growth factor receptor | 0.0334941 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0316138 |
| STC2 | stanniocalcin 2 | 0.029411 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0292714 |
| IL6ST | interleukin 6 signal transducer | 0.0265756 |
| H1-0 | H1.0 linker histone | 0.0260266 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0250333 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0241451 |
| FBXO32 | F-box protein 32 | 0.0240981 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0239945 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0238675 |
| RPL9 | ribosomal protein L9 | 0.0234002 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0228302 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0216038 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.02148 |
| TPI1 | triosephosphate isomerase 1 | 0.0212844 |
| SMAD3 | SMAD family member 3 | 0.0209329 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.020875 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0208092 |
| SGMS2 | sphingomyelin synthase 2 | 0.0207579 |
| FNBP1 | formin binding protein 1 | 0.0201275 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0201152 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0200003 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0196522 |
| SVIL | supervillin | 0.0193638 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0193036 |
| AXL | AXL receptor tyrosine kinase | 0.0191905 |
| DOCK5 | dedicator of cytokinesis 5 | 0.018702 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0185127 |
| SLK | STE20-like kinase | 0.0182082 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0177307 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0176146 |
| STC1 | stanniocalcin 1 | 0.0174561 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0174315 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0172763 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0171233 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0164279 |
| MX2 | MX dynamin-like GTPase 2 | 0.0158041 |
| AREG | amphiregulin | 0.0154831 |
| FAM107B | family with sequence similarity 107, member B | 0.015232 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0151893 |
| MYO6 | myosin VI | 0.0151246 |
| RTN4 | reticulon 4 | 0.0150393 |
| IL6R | interleukin 6 receptor | 0.0150381 |
| FAF2 | Fas associated factor family member 2 | 0.0149737 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0149024 |
| YBX3 | Y box binding protein 3 | 0.0148811 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0148147 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0147091 |
| JMJD1C | jumonji domain containing 1C | 0.0146986 |
| KLF6 | Kruppel-like factor 6 | 0.0145752 |
| GPHN | gephyrin | 0.0144743 |
| EZR | ezrin | 0.0144491 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0142547 |
| REST | RE1-silencing transcription factor | 0.0140917 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.0140834 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0140688 |
| NRP1 | neuropilin 1 | 0.0139512 |
| SLC16A6 | solute carrier family 16, member 6 | 0.0138011 |
| SET | SET nuclear proto-oncogene | 0.0137959 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0137445 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0136891 |
| CCND1 | cyclin D1 | 0.013659 |
| SFXN1 | sideroflexin 1 | 0.0135881 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0135302 |
| RPS2 | ribosomal protein S2 | 0.0135232 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0135187 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0133964 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0133428 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0133297 |
| SIRT1 | sirtuin 1 | 0.0132643 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0131189 |
| PTGR1 | prostaglandin reductase 1 | 0.0131183 |
| INHBA | inhibin, beta A | 0.0130248 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0129985 |
| PDS5A | PDS5 cohesin associated factor A | 0.0129743 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0128479 |
| CALB2 | calbindin 2 | 0.012811 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0125634 |
| DUSP5 | dual specificity phosphatase 5 | 0.0125485 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.012462 |
| MKI67 | marker of proliferation Ki-67 | 0.012459 |
| SFSWAP | splicing factor, suppressor of white-apricot family | 0.012254 |
| MEIS2 | Meis homeobox 2 | 0.0122239 |
| RACK1 | receptor for activated C kinase 1 | 0.0122212 |
| FRMD5 | FERM domain containing 5 | 0.0121471 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0121332 |
| HS6ST3 | heparan sulfate 6-O-sulfotransferase 3 | 0.0119725 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0119566 |
| FHL2 | four and a half LIM domains 2 | 0.0119163 |
| MYADM | myeloid-associated differentiation marker | 0.0118962 |
| DOCK10 | dedicator of cytokinesis 10 | 0.0118594 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.374002 |
| NRG1 | neuregulin 1 | -0.230299 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.222942 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.180578 |
| CANX | calnexin | -0.119346 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.114584 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.114226 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.104562 |
| HMGA2 | high mobility group AT-hook 2 | -0.102882 |
| PTMA | prothymosin, alpha | -0.10055 |
| ITGA1 | integrin, alpha 1 | -0.0999743 |
| GLIS3 | GLIS family zinc finger 3 | -0.0963408 |
| TMSB10 | thymosin beta 10 | -0.0909216 |
| VCL | vinculin | -0.0899436 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0846076 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0753378 |
| AEBP2 | AE binding protein 2 | -0.0745105 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0728703 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0689419 |
| INTS6 | integrator complex subunit 6 | -0.0671546 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0663394 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0663048 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0637229 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.059871 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0588157 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0541575 |
| GPC6 | glypican 6 | -0.0535642 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0529872 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0506105 |
| ASPH | aspartate beta-hydroxylase | -0.0497138 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0493052 |
| NDRG1 | N-myc downstream regulated 1 | -0.049186 |
| HLA-B | major histocompatibility complex, class I, B | -0.0485094 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0484362 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0476963 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0471982 |
| TMSB4X | thymosin beta 4, X-linked | -0.0448721 |
| PRELID2 | PRELI domain containing 2 | -0.0448418 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.04467 |
| PKM | pyruvate kinase, muscle | -0.0445715 |
| SYT1 | synaptotagmin I | -0.0443824 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0442403 |
| GNAS | GNAS complex locus | -0.0440261 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0436465 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0432735 |
| PLIN2 | perilipin 2 | -0.0429786 |
| RAI14 | retinoic acid induced 14 | -0.0413741 |
| COPA | coatomer protein complex, subunit alpha | -0.0400144 |
| VIM | vimentin | -0.0388091 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0377406 |
| PGK1 | phosphoglycerate kinase 1 | -0.0375347 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0373327 |
| LRRC23 | leucine rich repeat containing 23 | -0.0373319 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.037245 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0364168 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0361764 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0355606 |
| EFNA5 | ephrin-A5 | -0.0346693 |
| CALU | calumenin | -0.0346364 |
| S100A6 | S100 calcium binding protein A6 | -0.0341998 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0337446 |
| ERO1B | endoplasmic reticulum oxidoreductase 1 beta | -0.0335743 |
| FTL | ferritin, light polypeptide | -0.0335651 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0332624 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0323183 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0323056 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0321746 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0321646 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.031104 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0305377 |
| FAM20C | family with sequence similarity 20, member C | -0.0302677 |
| HDLBP | high density lipoprotein binding protein | -0.0298669 |
| CALR | calreticulin | -0.0297543 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0296882 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | -0.0296341 |
| SPAG9 | sperm associated antigen 9 | -0.0296276 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0295991 |
| AHR | aryl hydrocarbon receptor | -0.0295556 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0293837 |
| TGFB1 | transforming growth factor, beta 1 | -0.0293157 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0292372 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0291656 |
| CADM1 | cell adhesion molecule 1 | -0.0291119 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0290857 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0290459 |
| SFTPA2 | surfactant protein A2 | -0.028154 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.027917 |
| NAV1 | neuron navigator 1 | -0.0277719 |
| RPL35A | ribosomal protein L35a | -0.0276893 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0276636 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0276224 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0268414 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0267905 |
| GLUL | glutamate-ammonia ligase | -0.0261718 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0260726 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0258782 |
| B2M | beta-2-microglobulin | -0.0258662 |
| BSG | basigin (Ok blood group) | -0.0258194 |
| ACTN4 | actinin, alpha 4 | -0.0255652 |
| FBXO11 | F-box protein 11 | -0.0255412 |