| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Idarubicin (hydrochloride)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.17441 |
| RPS6 | ribosomal protein S6 | 0.160325 |
| EZR | ezrin | 0.11391 |
| FTL | ferritin, light polypeptide | 0.1075 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.102352 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0913573 |
| BCL2L1 | BCL2-like 1 | 0.0874108 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0865832 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0742724 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0706875 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0661947 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.065848 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0638955 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0620381 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0617532 |
| EGR1 | early growth response 1 | 0.0591591 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0517133 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0515562 |
| HM13 | histocompatibility (minor) 13 | 0.049831 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0470455 |
| EHBP1 | EH domain binding protein 1 | 0.0466627 |
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.0450502 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0435606 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0432344 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.043189 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0423594 |
| CUX1 | cut-like homeobox 1 | 0.0416893 |
| RPL4 | ribosomal protein L4 | 0.0413012 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0405804 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0404479 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.03908 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0390249 |
| DSPP | dentin sialophosphoprotein | 0.0387613 |
| CDK13 | cyclin-dependent kinase 13 | 0.0386345 |
| RPLP1 | ribosomal protein, large, P1 | 0.0384764 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0377036 |
| FAT1 | FAT atypical cadherin 1 | 0.0376172 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0375349 |
| ZNRF3 | zinc and ring finger 3 | 0.0373452 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0370288 |
| GOLGB1 | golgin B1 | 0.0369317 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0368682 |
| GNAS | GNAS complex locus | 0.0367115 |
| JMJD1C | jumonji domain containing 1C | 0.0359765 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0358415 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0351575 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | 0.0348208 |
| RAD51B | RAD51 paralog B | 0.034372 |
| MAP4 | microtubule-associated protein 4 | 0.0334874 |
| RPL37A | ribosomal protein L37a | 0.0334345 |
| BRD2 | bromodomain containing 2 | 0.0333543 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0332517 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0332333 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0331465 |
| RPS2 | ribosomal protein S2 | 0.0325595 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.032127 |
| VGF | VGF nerve growth factor inducible | 0.0317254 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0311414 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0310594 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0308761 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0307805 |
| RPS12 | ribosomal protein S12 | 0.0300871 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0298854 |
| SYAP1 | synapse associated protein 1 | 0.0295842 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0294276 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0293563 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.028883 |
| LAMB3 | laminin, beta 3 | 0.0286309 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0286045 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0285777 |
| GPHN | gephyrin | 0.0284135 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0283605 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0282657 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0280755 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0277812 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0273261 |
| FRMD5 | FERM domain containing 5 | 0.0271109 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.027063 |
| NRP1 | neuropilin 1 | 0.027045 |
| RPS8 | ribosomal protein S8 | 0.0268264 |
| RPL13A | ribosomal protein L13a | 0.0267825 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0262307 |
| NOP58 | NOP58 ribonucleoprotein | 0.0257324 |
| RPL26 | ribosomal protein L26 | 0.0257304 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0256855 |
| ETV6 | ets variant 6 | 0.025581 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0254861 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0254647 |
| PARD3B | par-3 family cell polarity regulator beta | 0.025284 |
| MYO1E | myosin IE | 0.0252577 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0252005 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.0250373 |
| GOLGA4 | golgin A4 | 0.0249946 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.0248428 |
| RPS17 | ribosomal protein S17 | 0.0247187 |
| CTBP2 | C-terminal binding protein 2 | 0.0243093 |
| RRBP1 | ribosome binding protein 1 | 0.0240674 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | 0.0240001 |
| FBXO11 | F-box protein 11 | 0.0238277 |
| EXOC4 | exocyst complex component 4 | 0.0236148 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0873447 |
| KRT8 | keratin 8, type II | -0.0701512 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.050691 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0505267 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0436297 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | -0.0425132 |
| RNF213 | ring finger protein 213 | -0.0424031 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0408526 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0374187 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.036986 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0369847 |
| PERP | PERP, TP53 apoptosis effector | -0.0367992 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0358543 |
| POTEF | POTE ankyrin domain family, member F | -0.0343899 |
| RYBP | RING1 and YY1 binding protein | -0.0343487 |
| CCNL1 | cyclin L1 | -0.0340106 |
| FAM3C | family with sequence similarity 3, member C | -0.0330953 |
| CST3 | cystatin C | -0.0328982 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0324973 |
| RBM33 | RNA binding motif protein 33 | -0.0321727 |
| MYOF | myoferlin | -0.032144 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0319391 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0313479 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0310158 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0308245 |
| RHEB | Ras homolog enriched in brain | -0.0305616 |
| MATR3 | matrin 3 | -0.029848 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -0.0295241 |
| STK4 | serine/threonine kinase 4 | -0.0293395 |
| B2M | beta-2-microglobulin | -0.0291963 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.028758 |
| CCND1 | cyclin D1 | -0.0287535 |
| XPO1 | exportin 1 | -0.0287138 |
| LDHA | lactate dehydrogenase A | -0.0286652 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0283153 |
| NKTR | natural killer cell triggering receptor | -0.0282215 |
| TOP1 | topoisomerase (DNA) I | -0.0280142 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0278362 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0276935 |
| KRT18 | keratin 18, type I | -0.0276782 |
| AFDN | afadin, adherens junction formation factor | -0.0275404 |
| CAPRIN1 | cell cycle associated protein 1 | -0.0269977 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0268443 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0268002 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0266263 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0265753 |
| OGA | O-GlcNAcase | -0.0261995 |
| TFG | TRK-fused gene | -0.0261531 |
| ZNF292 | zinc finger protein 292 | -0.0258082 |
| SNX9 | sorting nexin 9 | -0.0257022 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0256542 |
| EPCAM | epithelial cell adhesion molecule | -0.0255779 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0251683 |
| OLA1 | Obg-like ATPase 1 | -0.0249789 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0247257 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0239018 |
| PARD6B | par-6 family cell polarity regulator beta | -0.0236336 |
| SUCO | SUN domain containing ossification factor | -0.0235739 |
| PTEN | phosphatase and tensin homolog | -0.0234456 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | -0.0234356 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.023149 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0230367 |
| NCKAP1 | NCK-associated protein 1 | -0.0228742 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0228147 |
| MTMR3 | myotubularin related protein 3 | -0.0226905 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0214231 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0212779 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0212496 |
| ATP13A3 | ATPase type 13A3 | -0.0210997 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | -0.0208939 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0204326 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0203313 |
| SRPK2 | SRSF protein kinase 2 | -0.020301 |
| USP3 | ubiquitin specific peptidase 3 | -0.0202203 |
| CLDN1 | claudin 1 | -0.0201845 |
| FMR1 | fragile X mental retardation 1 | -0.0200808 |
| WTAP | Wilms tumor 1 associated protein | -0.0200709 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0199413 |
| RALGAPB | Ral GTPase activating protein, beta subunit (non-catalytic) | -0.0198982 |
| AZIN1 | antizyme inhibitor 1 | -0.0198981 |
| ARRDC3 | arrestin domain containing 3 | -0.0195643 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0195579 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0193024 |
| ECT2 | epithelial cell transforming 2 | -0.0191945 |
| SEPTIN7 | septin 7 | -0.0191535 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0190932 |
| KLHL24 | kelch-like family member 24 | -0.0190883 |
| CD47 | CD47 molecule | -0.0188251 |
| MB21D2 | Mab-21 domain containing 2 | -0.0185629 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0185277 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0184257 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0183873 |
| THOC2 | THO complex 2 | -0.018379 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0182297 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0182257 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0181505 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase | -0.018147 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0180915 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0180798 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | -0.0180695 |
