| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Idarubicin (hydrochloride)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS6 | ribosomal protein S6 | 0.143855 |
| RPS12 | ribosomal protein S12 | 0.0789431 |
| RPS2 | ribosomal protein S2 | 0.0728846 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0699635 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0661016 |
| EZR | ezrin | 0.0659457 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0588488 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0545801 |
| TPM3 | tropomyosin 3 | 0.0533269 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0484438 |
| TUBA1B | tubulin, alpha 1b | 0.0454109 |
| IPO7 | importin 7 | 0.0438427 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0426172 |
| FRMD5 | FERM domain containing 5 | 0.0401513 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0395079 |
| MKI67 | marker of proliferation Ki-67 | 0.0388304 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0381902 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0379067 |
| IGF2 | insulin-like growth factor 2 | 0.0378796 |
| SET | SET nuclear proto-oncogene | 0.0373734 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0372659 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0371251 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0360285 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0357746 |
| RPL4 | ribosomal protein L4 | 0.0355411 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0345976 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0344049 |
| RTN4 | reticulon 4 | 0.0340394 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0339189 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0338771 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.032161 |
| TPI1 | triosephosphate isomerase 1 | 0.0318728 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0318545 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0306036 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0305325 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0304566 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0303427 |
| STMN1 | stathmin 1 | 0.0302732 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0300087 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.029518 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0288059 |
| B2M | beta-2-microglobulin | 0.0287322 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0286657 |
| PCBP2 | poly(rC) binding protein 2 | 0.0284496 |
| WBP11 | WW domain binding protein 11 | 0.0283381 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0283229 |
| DDX24 | DEAD (Asp-Glu-Ala-Asp) box helicase 24 | 0.0280362 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0274687 |
| GNAS | GNAS complex locus | 0.027455 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0274157 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0272967 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0267439 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.0266275 |
| YBX3 | Y box binding protein 3 | 0.026621 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0263372 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0262504 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0260241 |
| ITGA6 | integrin, alpha 6 | 0.0256251 |
| SSH2 | slingshot protein phosphatase 2 | 0.0255772 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0252876 |
| GOLGA4 | golgin A4 | 0.0250415 |
| SYAP1 | synapse associated protein 1 | 0.0246965 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0246238 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0246051 |
| HLA-E | major histocompatibility complex, class I, E | 0.0245934 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0244474 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0243478 |
| PRDX1 | peroxiredoxin 1 | 0.0242123 |
| MSN | moesin | 0.0239536 |
| EMP1 | epithelial membrane protein 1 | 0.0235249 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | 0.0233492 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0233221 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0232787 |
| GOLGB1 | golgin B1 | 0.0231362 |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 | 0.0231356 |
| FAM111B | family with sequence similarity 111, member B | 0.0229588 |
| KIF5B | kinesin family member 5B | 0.0226629 |
| NOP56 | NOP56 ribonucleoprotein | 0.0219045 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0218314 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0218012 |
| PNN | pinin, desmosome associated protein | 0.0216974 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0215126 |
| DSPP | dentin sialophosphoprotein | 0.0214443 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0214428 |
| HLA-B | major histocompatibility complex, class I, B | 0.0213628 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0210542 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0209888 |
| CYCS | cytochrome c, somatic | 0.0207759 |
| CD9 | CD9 molecule | 0.0207696 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0207489 |
| TLN1 | talin 1 | 0.020624 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0206124 |
| HSPA4 | heat shock 70kDa protein 4 | 0.0204425 |
| CD44 | CD44 molecule (Indian blood group) | 0.0204225 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0203807 |
| BRCA1 | breast cancer 1, early onset | 0.0203333 |
| OGFOD1 | 2-oxoglutarate and iron-dependent oxygenase domain containing 1 | 0.0202358 |
| DSTN | destrin (actin depolymerizing factor) | 0.0201941 |
| RBBP6 | retinoblastoma binding protein 6 | 0.020189 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0200992 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.191524 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.177447 |
| TMSB10 | thymosin beta 10 | -0.136246 |
| INTS6 | integrator complex subunit 6 | -0.135445 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.127424 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.122279 |
| PGK1 | phosphoglycerate kinase 1 | -0.09147 |
| RPL35A | ribosomal protein L35a | -0.0883871 |
| SYT1 | synaptotagmin I | -0.0883784 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0876902 |
| RPS24 | ribosomal protein S24 | -0.072982 |
| ACTG1 | actin gamma 1 | -0.0674901 |
| KRT8 | keratin 8, type II | -0.0669538 |
| ACTN4 | actinin, alpha 4 | -0.066394 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0658278 |
| KRT18 | keratin 18, type I | -0.064009 |
| ATXN1 | ataxin 1 | -0.0612848 |
| RPLP1 | ribosomal protein, large, P1 | -0.0605395 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0573341 |
| RPL23 | ribosomal protein L23 | -0.0565599 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0549573 |
| LDHA | lactate dehydrogenase A | -0.0542173 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0502541 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0498138 |
| RPL11 | ribosomal protein L11 | -0.0486292 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0485502 |
| OXR1 | oxidation resistance 1 | -0.0482905 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0463383 |
| CDH13 | cadherin 13 | -0.0462753 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0452762 |
| ETNK1 | ethanolamine kinase 1 | -0.0451676 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.0425781 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0422739 |
| PERP | PERP, TP53 apoptosis effector | -0.0395815 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0390582 |
| MORF4L2 | mortality factor 4 like 2 | -0.0387963 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0370903 |
| RPL19 | ribosomal protein L19 | -0.0369927 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0368495 |
| RPLP0 | ribosomal protein, large, P0 | -0.0363854 |
| TNS3 | tensin 3 | -0.0352971 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0350435 |
| RPL32 | ribosomal protein L32 | -0.0349815 |
| TMEM123 | transmembrane protein 123 | -0.0342359 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | -0.0340911 |
| RPS23 | ribosomal protein S23 | -0.0339502 |
| ENO1 | enolase 1, (alpha) | -0.0339008 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0329041 |
| RPL31 | ribosomal protein L31 | -0.0323933 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0323251 |
| PROX1 | prospero homeobox 1 | -0.0320358 |
| RPL27A | ribosomal protein L27a | -0.0317792 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0316141 |
| RPS21 | ribosomal protein S21 | -0.0315984 |
| TFRC | transferrin receptor | -0.0315324 |
| RPLP2 | ribosomal protein, large, P2 | -0.0311824 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0311508 |
| ANKRD10 | ankyrin repeat domain 10 | -0.030225 |
| THOC2 | THO complex 2 | -0.0295463 |
| RUNX1 | runt-related transcription factor 1 | -0.0294442 |
| CCND1 | cyclin D1 | -0.0290039 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0287674 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0285108 |
| MT2A | metallothionein 2A | -0.0283683 |
| HDAC4 | histone deacetylase 4 | -0.0280019 |
| RPL34 | ribosomal protein L34 | -0.0279362 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0277534 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0276386 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0270138 |
| POTEF | POTE ankyrin domain family, member F | -0.0268967 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.026602 |
| NAV2 | neuron navigator 2 | -0.0264765 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0262042 |
| MYL12B | myosin, light chain 12B, regulatory | -0.025938 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0256951 |
| MED21 | mediator complex subunit 21 | -0.0254759 |
| RPL7 | ribosomal protein L7 | -0.0254554 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0253989 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0252703 |
| RPS5 | ribosomal protein S5 | -0.0250958 |
| PHF14 | PHD finger protein 14 | -0.0250506 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0248044 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.024616 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0240799 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0239893 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.023941 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0236789 |
| SECISBP2 | SECIS binding protein 2 | -0.0236683 |
| RNF43 | ring finger protein 43 | -0.0235984 |
| RBMX | RNA binding motif protein, X-linked | -0.0234367 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0233371 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.023225 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0230129 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0229967 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0229933 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0228629 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0228306 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.022641 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0225396 |
| RCC1 | regulator of chromosome condensation 1 | -0.0225089 |
