| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Idarubicin (hydrochloride)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STC1 | stanniocalcin 1 | 0.232724 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.149352 |
| HMGA2 | high mobility group AT-hook 2 | 0.138921 |
| FN1 | fibronectin 1 | 0.116929 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.100072 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0924007 |
| RPS6 | ribosomal protein S6 | 0.0891491 |
| HLA-B | major histocompatibility complex, class I, B | 0.0831206 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0705518 |
| FAM13A | family with sequence similarity 13, member A | 0.0698961 |
| INHBA | inhibin, beta A | 0.0687361 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0634062 |
| RPS12 | ribosomal protein S12 | 0.0608825 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0605449 |
| FMNL2 | formin-like 2 | 0.0538943 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0523407 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0505291 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0487704 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.046629 |
| B2M | beta-2-microglobulin | 0.0455641 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0454223 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0445278 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0440551 |
| MT2A | metallothionein 2A | 0.0435039 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0419465 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0411962 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0410574 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0408205 |
| CD99 | CD99 molecule | 0.0401958 |
| YBX3 | Y box binding protein 3 | 0.0401599 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0390776 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0388017 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0382457 |
| MYO10 | myosin X | 0.0381222 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0376719 |
| TPM3 | tropomyosin 3 | 0.0376595 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0372942 |
| CALR | calreticulin | 0.0371445 |
| TLN1 | talin 1 | 0.0365664 |
| RTN4 | reticulon 4 | 0.035654 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0336612 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0332901 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0332892 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0330308 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0326678 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0325125 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0324537 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0322656 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.031936 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0315054 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.0313173 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 | 0.0313022 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0310022 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0307507 |
| HLA-A | major histocompatibility complex, class I, A | 0.0303199 |
| HLA-E | major histocompatibility complex, class I, E | 0.0301019 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0297533 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.029748 |
| SFRP1 | secreted frizzled-related protein 1 | 0.0294095 |
| RPL4 | ribosomal protein L4 | 0.0293834 |
| FRMD6 | FERM domain containing 6 | 0.0280808 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0278845 |
| RUNX1 | runt-related transcription factor 1 | 0.0277064 |
| RPS2 | ribosomal protein S2 | 0.0274764 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0273724 |
| RPS19 | ribosomal protein S19 | 0.0273504 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0269318 |
| YBX1 | Y box binding protein 1 | 0.0265627 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.025916 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0256169 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0255659 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0255659 |
| SFTPA2 | surfactant protein A2 | 0.0253238 |
| CANX | calnexin | 0.0252151 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0250834 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0249232 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0249064 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0246214 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0245261 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0240513 |
| RPS8 | ribosomal protein S8 | 0.0239983 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0239907 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0238813 |
| FNBP1 | formin binding protein 1 | 0.0235135 |
| BRD2 | bromodomain containing 2 | 0.0231852 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0226423 |
| MSN | moesin | 0.0225616 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0224368 |
| MXI1 | MAX interactor 1, dimerization protein | 0.022178 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0219692 |
| NPTX1 | neuronal pentraxin I | 0.021917 |
| RASA2 | RAS p21 protein activator 2 | 0.0218947 |
| MMP12 | matrix metallopeptidase 12 | 0.0217529 |
| ATP13A3 | ATPase type 13A3 | 0.021712 |
| RND3 | Rho family GTPase 3 | 0.0214894 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0214099 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0209368 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0208691 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0207968 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.0205732 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | -0.203125 |
| COL1A1 | collagen, type I, alpha 1 | -0.107077 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0993769 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.099018 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0954333 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0941763 |
| TMSB10 | thymosin beta 10 | -0.0892444 |
| ACTG1 | actin gamma 1 | -0.080805 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0802798 |
| INTS6 | integrator complex subunit 6 | -0.0797205 |
| VIM | vimentin | -0.0729181 |
| VCL | vinculin | -0.0682328 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0637227 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0615175 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0614897 |
| CALD1 | caldesmon 1 | -0.0568889 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0555179 |
| LDHA | lactate dehydrogenase A | -0.0545203 |
| TPM4 | tropomyosin 4 | -0.0533815 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.048161 |
| OXR1 | oxidation resistance 1 | -0.0478298 |
| COL1A2 | collagen, type I, alpha 2 | -0.0456565 |
| RPL35A | ribosomal protein L35a | -0.044911 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0433908 |
| DIAPH2 | diaphanous-related formin 2 | -0.0410324 |
| PDE8A | phosphodiesterase 8A | -0.0404879 |
| EMP1 | epithelial membrane protein 1 | -0.039541 |
| POTEF | POTE ankyrin domain family, member F | -0.0394577 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0394512 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0378756 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0369653 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0366475 |
| CCDC102B | coiled-coil domain containing 102B | -0.0364684 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0354058 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0353952 |
| EGFR | epidermal growth factor receptor | -0.035383 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0352469 |
| PGK1 | phosphoglycerate kinase 1 | -0.035029 |
| FRMD4A | FERM domain containing 4A | -0.0349782 |
| CCND1 | cyclin D1 | -0.0343501 |
| FTL | ferritin, light polypeptide | -0.0329893 |
| COL5A3 | collagen, type V, alpha 3 | -0.0327625 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0327116 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0321008 |
| FBN1 | fibrillin 1 | -0.0310485 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0295558 |
| SNX14 | sorting nexin 14 | -0.0294897 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0293314 |
| SETD5 | SET domain containing 5 | -0.0291918 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0289854 |
| AHNAK | AHNAK nucleoprotein | -0.0288817 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.028835 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0287307 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0286917 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0285747 |
| RPS24 | ribosomal protein S24 | -0.0284727 |
| NAV1 | neuron navigator 1 | -0.0281381 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0280148 |
| RPS16 | ribosomal protein S16 | -0.0279639 |
| S100A6 | S100 calcium binding protein A6 | -0.0278706 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0274501 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0273603 |
| ERBIN | erbb2 interacting protein | -0.0268609 |
| KIAA1549L | KIAA1549-like | -0.0267669 |
| PRRX1 | paired related homeobox 1 | -0.0261804 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0260931 |
| ATXN1 | ataxin 1 | -0.0253989 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0253372 |
| ENO1 | enolase 1, (alpha) | -0.0244512 |
| PKM | pyruvate kinase, muscle | -0.0242339 |
| SEC24D | SEC24 family member D | -0.0241595 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0238797 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0237971 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0237861 |
| GLG1 | golgi glycoprotein 1 | -0.0236878 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0236511 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0236392 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0236352 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0235869 |
| TPM1 | tropomyosin 1 (alpha) | -0.0234808 |
| CDH13 | cadherin 13 | -0.0234566 |
| PRSS23 | protease, serine, 23 | -0.0232217 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.0231775 |
| PRR16 | proline rich 16 | -0.0231356 |
| DGKI | diacylglycerol kinase, iota | -0.0230987 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | -0.0229335 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0228231 |
| TCF12 | transcription factor 12 | -0.0226612 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0223688 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0221098 |
| LMO7 | LIM domain 7 | -0.0216988 |
| RPS13 | ribosomal protein S13 | -0.0214947 |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 | -0.0214654 |
| NREP | neuronal regeneration related protein | -0.0211786 |
| CALU | calumenin | -0.0208765 |
| COL5A2 | collagen, type V, alpha 2 | -0.0208275 |
| RPL31 | ribosomal protein L31 | -0.0203769 |
| SOCS5 | suppressor of cytokine signaling 5 | -0.0202758 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0201764 |
| RPL19 | ribosomal protein L19 | -0.0200841 |
