Idiopathic Pulmonary Fibrosis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Chronic and progressive fibrosis of the lung parenchyma of unknown cause. (Experimental Factor Ontology, EFO_0000768)
External Link https://www.disgenet.org/browser/0/1/0/C1800706
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Genes

731 genes associated with the disease Idiopathic Pulmonary Fibrosis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACE angiotensin I converting enzyme
ACE2 angiotensin I converting enzyme 2
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
ACR acrosin
ACTB actin, beta
ADAM10 ADAM metallopeptidase domain 10
ADAM17 ADAM metallopeptidase domain 17
ADAM33 ADAM metallopeptidase domain 33
ADAR adenosine deaminase, RNA-specific
ADARB1 adenosine deaminase, RNA-specific, B1
ADGRE2 adhesion G protein-coupled receptor E2
ADGRE5 adhesion G protein-coupled receptor E5
ADIPOQ adiponectin, C1Q and collagen domain containing
ADORA2B adenosine A2b receptor
AGER advanced glycosylation end product-specific receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AGTR2 angiotensin II receptor, type 2
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AICDA activation-induced cytidine deaminase
AIM2 absent in melanoma 2
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
AKAP13 A kinase (PRKA) anchor protein 13
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALK anaplastic lymphoma receptor tyrosine kinase
ALOX5 arachidonate 5-lipoxygenase
ALPI alkaline phosphatase, intestinal
ALPP alkaline phosphatase, placental
AMBP alpha-1-microglobulin/bikunin precursor
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
ANK1 ankyrin 1, erythrocytic
ANO1 anoctamin 1, calcium activated chloride channel
ANXA1 annexin A1
ANXA2 annexin A2
ANXA5 annexin A5
AOC3 amine oxidase, copper containing 3
APCS amyloid P component, serum
APOA1 apolipoprotein A-I
AQP1 aquaporin 1 (Colton blood group)
AREL1 apoptosis resistant E3 ubiquitin protein ligase 1
ARG1 arginase 1
ARHGAP12 Rho GTPase activating protein 12
ARHGAP35 Rho GTPase activating protein 35
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ASCC1 activating signal cointegrator 1 complex subunit 1
ASPRV1 aspartic peptidase, retroviral-like 1
ATF3 activating transcription factor 3
ATF4 activating transcription factor 4
ATG4B autophagy related 4B, cysteine peptidase
ATP11A ATPase, class VI, type 11A
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
B3GAT3 beta-1,3-glucuronyltransferase 3
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BCHE butyrylcholinesterase
BCL2 B-cell CLL/lymphoma 2
BDNF brain-derived neurotrophic factor
BECN1 beclin 1, autophagy related
BHLHE40 basic helix-loop-helix family, member e40
BIRC5 baculoviral IAP repeat containing 5
BMP3 bone morphogenetic protein 3
BMP4 bone morphogenetic protein 4
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BRCA2 breast cancer 2, early onset
BRD4 bromodomain containing 4
BTK Bruton agammaglobulinemia tyrosine kinase
C1ORF228 chromosome 1 open reading frame 228
C3 complement component 3
C3AR1 complement component 3a receptor 1
C5AR1 complement component 5a receptor 1
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP4 caspase 4, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CCL17 chemokine (C-C motif) ligand 17
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCL2 chemokine (C-C motif) ligand 2
CCL21 chemokine (C-C motif) ligand 21
CCL22 chemokine (C-C motif) ligand 22
CCL3 chemokine (C-C motif) ligand 3
CCL4 chemokine (C-C motif) ligand 4
CCL4L1 chemokine (C-C motif) ligand 4-like 1
CCL4L2 chemokine (C-C motif) ligand 4-like 2
CCL5 chemokine (C-C motif) ligand 5
CCL7 chemokine (C-C motif) ligand 7
CCL8 chemokine (C-C motif) ligand 8
CCN1 cellular communication network factor 1
CCN2 cellular communication network factor 2
CCNA2 cyclin A2
CCND1 cyclin D1
CCNE2 cyclin E2
CCR10 chemokine (C-C motif) receptor 10
CCR2 chemokine (C-C motif) receptor 2
CCR7 chemokine (C-C motif) receptor 7
CD151 CD151 molecule (Raph blood group)
CD163 CD163 molecule
CD248 CD248 molecule, endosialin
CD274 CD274 molecule
CD276 CD276 molecule
CD28 CD28 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD40 CD40 molecule, TNF receptor superfamily member 5
CD46 CD46 molecule, complement regulatory protein
CD47 CD47 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD68 CD68 molecule
CDCP1 CUB domain containing protein 1
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CEL carboxyl ester lipase
CEMIP cell migration inducing protein, hyaluronan binding
CETN1 centrin, EF-hand protein, 1
CFLAR CASP8 and FADD-like apoptosis regulator
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CKAP4 cytoskeleton-associated protein 4
CNR1 cannabinoid receptor 1 (brain)
CNR2 cannabinoid receptor 2 (macrophage)
COL18A1 collagen, type XVIII, alpha 1
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
COL4A5 collagen, type IV, alpha 5
COMP cartilage oligomeric matrix protein
COX1
COX2
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CR2 complement component (3d/Epstein Barr virus) receptor 2
CREBBP CREB binding protein
CRIP1 cysteine-rich protein 1 (intestinal)
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRLF1 cytokine receptor-like factor 1
CRMP1 collapsin response mediator protein 1
CRP C-reactive protein, pentraxin-related
CRYAB crystallin, alpha B
CSF1 colony stimulating factor 1 (macrophage)
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF3 colony stimulating factor 3 (granulocyte)
CSRP1 cysteine and glycine-rich protein 1
CST3 cystatin C
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSA cathepsin A
CTSL cathepsin L
CTSS cathepsin S
CUX1 cut-like homeobox 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
CXCR5 chemokine (C-X-C motif) receptor 5
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DAPK2 death-associated protein kinase 2
DCN decorin
DCPS decapping enzyme, scavenger
DDIT3 DNA-damage-inducible transcript 3
DDR1 discoidin domain receptor tyrosine kinase 1
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DENR density-regulated protein
DEPTOR DEP domain containing MTOR-interacting protein
DICER1 dicer 1, ribonuclease type III
DIO2 deiodinase, iodothyronine, type II
DKC1 dyskeratosis congenita 1, dyskerin
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAH8 dynein, axonemal, heavy chain 8
DNM1L dynamin 1-like
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DPP9 dipeptidyl-peptidase 9
DROSHA drosha, ribonuclease type III
DSP desmoplakin
DUSP10 dual specificity phosphatase 10
E2F1 E2F transcription factor 1
EBI3 Epstein-Barr virus induced 3
EBNA1BP2 EBNA1 binding protein 2
ECE1 endothelin converting enzyme 1
ECT2 epithelial cell transforming 2
EDN1 endothelin 1
EEF2K eukaryotic elongation factor 2 kinase
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EGR1 early growth response 1
EIF1 eukaryotic translation initiation factor 1
ELAVL2 ELAV like neuron-specific RNA binding protein 2
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ELK1 ELK1, member of ETS oncogene family
ELMOD2 ELMO/CED-12 domain containing 2
ELN elastin
ELOVL6 ELOVL fatty acid elongase 6
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EP300 E1A binding protein p300
EPHA3 EPH receptor A3
EPRS1 glutamyl-prolyl-tRNA synthetase 1
ERBB2 erb-b2 receptor tyrosine kinase 2
ERN1 endoplasmic reticulum to nucleus signaling 1
ERN2 endoplasmic reticulum to nucleus signaling 2
ESR1 estrogen receptor 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F10 coagulation factor X
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
F2RL3 coagulation factor II (thrombin) receptor-like 3
FAM13A family with sequence similarity 13, member A
FAM212B family with sequence similarity 212, member B
FAP fibroblast activation protein, alpha
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FBLN5 fibulin 5
FBN1 fibrillin 1
FBN2 fibrillin 2
FBRS fibrosin
FBXO8 F-box protein 8
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FER fer (fps/fes related) tyrosine kinase
FGF1 fibroblast growth factor 1 (acidic)
FGF10 fibroblast growth factor 10
FGF2 fibroblast growth factor 2 (basic)
FGF23 fibroblast growth factor 23
FGF7 fibroblast growth factor 7
FGF9 fibroblast growth factor 9
FGFR2 fibroblast growth factor receptor 2
FHIT fragile histidine triad
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FKBP10 FK506 binding protein 10, 65 kDa
FN1 fibronectin 1
FOLR2 folate receptor 2 (fetal)
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL2 FOS-like antigen 2
FOXA2 forkhead box A2
FOXF1 forkhead box F1
FOXM1 forkhead box M1
FOXO3 forkhead box O3
FPR2 formyl peptide receptor 2
FSD1 fibronectin type III and SPRY domain containing 1
FST follistatin
FZD1 frizzled class receptor 1
FZD2 frizzled class receptor 2
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GAS6 growth arrest-specific 6
GATA6 GATA binding protein 6
GDF10 growth differentiation factor 10
GDF15 growth differentiation factor 15
GGT1 gamma-glutamyltransferase 1
GGTLC3 gamma-glutamyltransferase light chain 3
GIF gastric intrinsic factor (vitamin B synthesis)
GLB1 galactosidase, beta 1
GLI1 GLI family zinc finger 1
GLI2 GLI family zinc finger 2
GLRX glutaredoxin (thioltransferase)
GORASP1 golgi reassembly stacking protein 1, 65kDa
GPER1 G protein-coupled estrogen receptor 1
GPR6 G protein-coupled receptor 6
GPR84 G protein-coupled receptor 84
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GPX4 glutathione peroxidase 4
GRAP2 GRB2-related adaptor protein 2
GREM1 gremlin 1, DAN family BMP antagonist
GRHL2 grainyhead-like 2 (Drosophila)
HAVCR2 hepatitis A virus cellular receptor 2
HBE1 hemoglobin, epsilon 1
HDAC2 histone deacetylase 2
HDAC6 histone deacetylase 6
HDAC7 histone deacetylase 7
HDAC8 histone deacetylase 8
HDAC9 histone deacetylase 9
HFE hemochromatosis
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HGFAC HGF activator
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIPK2 homeodomain interacting protein kinase 2
HIST1H2AH histone cluster 1, H2ah
HIST1H4A histone cluster 1, H4a
HIST1H4B histone cluster 1, H4b
HIST1H4C histone cluster 1, H4c
HIST1H4D histone cluster 1, H4d
HIST1H4E histone cluster 1, H4e
HIST1H4F histone cluster 1, H4f
HIST1H4H histone cluster 1, H4h
HIST1H4I histone cluster 1, H4i
HIST1H4J histone cluster 1, H4j
HIST1H4K histone cluster 1, H4k
HIST1H4L histone cluster 1, H4l
HIST2H4A histone cluster 2, H4a
HIST2H4B histone cluster 2, H4b
HIST4H4 histone cluster 4, H4
HK2 hexokinase 2
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLF hepatic leukemia factor
HMGB1 high mobility group box 1
HMOX1 heme oxygenase 1
HNF1B HNF1 homeobox B
HOXA2 homeobox A2
HOXD13 homeobox D13
HP haptoglobin
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HPS1 Hermansky-Pudlak syndrome 1
HRG histidine-rich glycoprotein
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
HS6ST2 heparan sulfate 6-O-sulfotransferase 2
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA1A heat shock 70kDa protein 1A
HSPA1B heat shock 70kDa protein 1B
HSPA1L heat shock 70kDa protein 1-like
HSPA4 heat shock 70kDa protein 4
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPB1 heat shock 27kDa protein 1
HSPB2 heat shock 27kDa protein 2
HSPB3 heat shock 27kDa protein 3
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IAPP islet amyloid polypeptide
ICAM1 intercellular adhesion molecule 1
IFNG interferon, gamma
IFT20 intraflagellar transport 20
IFT88 intraflagellar transport 88
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP3 insulin-like growth factor binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
IL10 interleukin 10
IL11 interleukin 11
IL13 interleukin 13
IL17A interleukin 17A
IL17RA interleukin 17 receptor A
IL18 interleukin 18
IL18R1 interleukin 18 receptor 1
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL25 interleukin 25
IL33 interleukin 33
IL37 interleukin 37
IL4 interleukin 4
IL4R interleukin 4 receptor
IL6 interleukin 6
IL6R interleukin 6 receptor
IL6ST interleukin 6 signal transducer
IL9 interleukin 9
ING4 inhibitor of growth family, member 4
INTS1 integrator complex subunit 1
IRF5 interferon regulatory factor 5
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGB8 integrin, beta 8
ITK IL2-inducible T-cell kinase
JAG1 jagged 1
JAK2 Janus kinase 2
JUN jun proto-oncogene
JUNB jun B proto-oncogene
JUND jun D proto-oncogene
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIF15 kinesin family member 15
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
KL klotho
KLF4 Kruppel-like factor 4 (gut)
KLRC4-KLRK1 KLRC4-KLRK1 readthrough
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KNG1 kininogen 1
KRAS Kirsten rat sarcoma viral oncogene homolog
KREMEN1 kringle containing transmembrane protein 1
KRT20 keratin 20, type I
KRT5 keratin 5, type II
KRT7 keratin 7, type II
KRT8 keratin 8, type II
L1CAM L1 cell adhesion molecule
LAMA1 laminin, alpha 1
LAMA3 laminin, alpha 3
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
LCLAT1 lysocardiolipin acyltransferase 1
LDHA lactate dehydrogenase A
LEF1 lymphoid enhancer-binding factor 1
LEP leptin
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS7 lectin, galactoside-binding, soluble, 7
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LIN28B lin-28 homolog B (C. elegans)
LOC102725035 leukocyte immunoglobulin-like receptor subfamily B member 3
LOX lysyl oxidase
LOXL1 lysyl oxidase-like 1
LOXL2 lysyl oxidase-like 2
LOXL3 lysyl oxidase-like 3
LOXL4 lysyl oxidase-like 4
LPA lipoprotein, Lp(a)
LPAR1 lysophosphatidic acid receptor 1
LTA4H leukotriene A4 hydrolase
LTBP1 latent transforming growth factor beta binding protein 1
LTBP2 latent transforming growth factor beta binding protein 2
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAGT1 magnesium transporter 1
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAP3K10 mitogen-activated protein kinase kinase kinase 10
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
MARCHF1 membrane associated ring-CH-type finger 1
MARCKS myristoylated alanine-rich protein kinase C substrate
MARK2 MAP/microtubule affinity-regulating kinase 2
MECP2 methyl CpG binding protein 2
MERTK MER proto-oncogene, tyrosine kinase
METAP2 methionyl aminopeptidase 2
MGP matrix Gla protein
MICA MHC class I polypeptide-related sequence A
MID1 midline 1
MIP major intrinsic protein of lens fiber
MLXIP MLX interacting protein
MMP1 matrix metallopeptidase 1
MMP13 matrix metallopeptidase 13
MMP19 matrix metallopeptidase 19
MMP2 matrix metallopeptidase 2
MMP24 matrix metallopeptidase 24 (membrane-inserted)
MMP28 matrix metallopeptidase 28
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MMRN1 multimerin 1
MOK MOK protein kinase
MPG N-methylpurine-DNA glycosylase
MPO myeloperoxidase
MPST mercaptopyruvate sulfurtransferase
MRC1 mannose receptor, C type 1
MRTFA myocardin related transcription factor A
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MSC musculin
MSR1 macrophage scavenger receptor 1
MST1 macrophage stimulating 1
MSTO1 misato 1, mitochondrial distribution and morphology regulator
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MUC16 mucin 16, cell surface associated
MUC19 mucin 19, oligomeric
MUC5B mucin 5B, oligomeric mucus/gel-forming
MUC6 mucin 6, oligomeric mucus/gel-forming
MYBPH myosin binding protein H
MYDGF myeloid-derived growth factor
MYLIP myosin regulatory light chain interacting protein
MZB1 marginal zone B and B1 cell-specific protein
NEU1 sialidase 1 (lysosomal sialidase)
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NID2 nidogen 2 (osteonidogen)
NLRP1 NLR family, pyrin domain containing 1
NLRP3 NLR family, pyrin domain containing 3
NOD2 nucleotide-binding oligomerization domain containing 2
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOTCH1 notch 1
NOX4 NADPH oxidase 4
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A3 nuclear receptor subfamily 4, group A, member 3
NREP neuronal regeneration related protein
NRF1 nuclear respiratory factor 1
NT5E 5'-nucleotidase, ecto (CD73)
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21
NUMB numb homolog (Drosophila)
NUP98 nucleoporin 98kDa
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1
OSM oncostatin M
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
P4HA3 prolyl 4-hydroxylase, alpha polypeptide III
PADI2 peptidyl arginine deiminase, type II
PADI4 peptidyl arginine deiminase, type IV
PARN poly(A)-specific ribonuclease
PARP1 poly (ADP-ribose) polymerase 1
PARP9 poly (ADP-ribose) polymerase family, member 9
PARPBP PARP1 binding protein
PCNA proliferating cell nuclear antigen
PCSK9 proprotein convertase subtilisin/kexin type 9
PDCD1 programmed cell death 1
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PELI1 pellino E3 ubiquitin protein ligase 1
PF4 platelet factor 4
PGAM5 phosphoglycerate mutase family member 5
PHGDH phosphoglycerate dehydrogenase
PIAS4 protein inhibitor of activated STAT, 4
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PINK1 PTEN induced putative kinase 1
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKD2 polycystic kidney disease 2 (autosomal dominant)
PLAU plasminogen activator, urokinase
PLG plasminogen
PLK1 polo-like kinase 1
PLN phospholamban
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PLXNC1 plexin C1
POLDIP2 polymerase (DNA-directed), delta interacting protein 2
POSTN periostin, osteoblast specific factor
POU2AF1 POU class 2 associating factor 1
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPL periplakin
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
PRC1 protein regulator of cytokinesis 1
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKD1 protein kinase D1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRRX1 paired related homeobox 1
PSG2 pregnancy specific beta-1-glycoprotein 2
PSIP1 PC4 and SFRS1 interacting protein 1
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSME4 proteasome (prosome, macropain) activator subunit 4
PTCH1 patched 1
PTEN phosphatase and tensin homolog
PTGFR prostaglandin F receptor (FP)
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTPA protein phosphatase 2 phosphatase activator
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPN5 protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
PTX3 pentraxin 3, long
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
RABEPK Rab9 effector protein with kelch motifs
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAD51 RAD51 recombinase
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RBM45 RNA binding motif protein 45
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
REN renin
RET ret proto-oncogene
RETN resistin
RETNLB resistin like beta
RFC2 replication factor C (activator 1) 2, 40kDa
RGS2 regulator of G-protein signaling 2
RGS6 regulator of G-protein signaling 6
RHCE Rh blood group, CcEe antigens
RHO rhodopsin
RHOA ras homolog family member A
RIPK3 receptor-interacting serine-threonine kinase 3
RND3 Rho family GTPase 3
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
ROM1 retinal outer segment membrane protein 1
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RPE65 retinal pigment epithelium-specific protein 65kDa
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
RPSA ribosomal protein SA
RSPO2 R-spondin 2
RTEL1 regulator of telomere elongation helicase 1
RUNX2 runt-related transcription factor 2
RXFP1 relaxin/insulin-like family peptide receptor 1
S100A12 S100 calcium binding protein A12
S100A4 S100 calcium binding protein A4
S100A9 S100 calcium binding protein A9
SART3 squamous cell carcinoma antigen recognized by T cells 3
SCLY selenocysteine lyase
SDC1 syndecan 1
SDC2 syndecan 2
SDF4 stromal cell derived factor 4
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SEPP1 selenoprotein P, plasma, 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SFTPA1 surfactant protein A1
SFTPA2 surfactant protein A2
SFTPB surfactant protein B
SFTPC surfactant protein C
SFTPD surfactant protein D
SH3BP2 SH3-domain binding protein 2
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SIPA1 signal-induced proliferation-associated 1
SIRT1 sirtuin 1
SIRT3 sirtuin 3
SIRT6 sirtuin 6
SIRT7 sirtuin 7
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC12A9 solute carrier family 12, member 9
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SLC52A2 solute carrier family 52 (riboflavin transporter), member 2
SLURP1 secreted LY6/PLAUR domain containing 1
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SMN1 survival of motor neuron 1, telomeric
SMN2 survival of motor neuron 2, centromeric
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SNAI1 snail family zinc finger 1
SNAI2 snail family zinc finger 2
SOAT1 sterol O-acyltransferase 1
SOCS1 suppressor of cytokine signaling 1
SOD3 superoxide dismutase 3, extracellular
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPHK1 sphingosine kinase 1
SPP1 secreted phosphoprotein 1
SPPL2C signal peptide peptidase like 2C
SPRY2 sprouty homolog 2 (Drosophila)
SRR serine racemase
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT4 signal transducer and activator of transcription 4
STC1 stanniocalcin 1
STK17B serine/threonine kinase 17b
STK3 serine/threonine kinase 3
STX17 syntaxin 17
SULF2 sulfatase 2
SYT1 synaptotagmin I
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3
TAGLN transgelin
TAL1 T-cell acute lymphocytic leukemia 1
TAZ tafazzin
TBPL1 TBP-like 1
TBX21 T-box 21
TEK TEK tyrosine kinase, endothelial
TERT telomerase reverse transcriptase
TET1 tet methylcytosine dioxygenase 1
TFRC transferrin receptor
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGM2 transglutaminase 2
THY1 Thy-1 cell surface antigen
TIAM1 T-cell lymphoma invasion and metastasis 1
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP3 TIMP metallopeptidase inhibitor 3
TIMP4 TIMP metallopeptidase inhibitor 4
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR7 toll-like receptor 7
TLR9 toll-like receptor 9
TM4SF5 transmembrane 4 L six family member 5
TM7SF2 transmembrane 7 superfamily member 2
TMBIM6 transmembrane BAX inhibitor motif containing 6
TMOD3 tropomodulin 3 (ubiquitous)
TMPRSS4 transmembrane protease, serine 4
TNC tenascin C
TNF tumor necrosis factor
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TNS1 tensin 1
TOLLIP toll interacting protein
TP53 tumor protein p53
TP63 tumor protein p63
TPMT thiopurine S-methyltransferase
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TSLP thymic stromal lymphopoietin
TSPAN1 tetraspanin 1
TTR transthyretin
TTYH1 tweety family member 1
TUBA1B tubulin, alpha 1b
TWIST1 twist family bHLH transcription factor 1
TXN thioredoxin
TYRO3 TYRO3 protein tyrosine kinase
TYRP1 tyrosinase-related protein 1
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)
UTRN utrophin
UVRAG UV radiation resistance associated
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
VIM vimentin
VIP vasoactive intestinal peptide
VPS51 vacuolar protein sorting 51 homolog (S. cerevisiae)
VWF von Willebrand factor
WISP1 WNT1 inducible signaling pathway protein 1
WISP2 WNT1 inducible signaling pathway protein 2
WNK1 WNK lysine deficient protein kinase 1
WNT1 wingless-type MMTV integration site family, member 1
WNT5A wingless-type MMTV integration site family, member 5A
WNT7B wingless-type MMTV integration site family, member 7B
WWTR1 WW domain containing transcription regulator 1
XBP1 X-box binding protein 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XK X-linked Kx blood group
XPR1 xenotropic and polytropic retrovirus receptor 1
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
YAP1 Yes-associated protein 1
ZEB1 zinc finger E-box binding homeobox 1