Idiosyncratic drug effect_Hepatic Tissue_GSE2825 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE2825
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Genes

600 genes differentially expressed during Idiosyncratic drug effect_Hepatic Tissue_GSE2825 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
COL11A1 collagen, type XI, alpha 1 3.41582
PDGFD platelet derived growth factor D 3.1802
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 3.08454
ING1 inhibitor of growth family, member 1 2.98781
MAPK11 mitogen-activated protein kinase 11 2.95576
LRG1 leucine-rich alpha-2-glycoprotein 1 2.89639
IPO4 importin 4 2.8213
TMEM60 transmembrane protein 60 2.67593
FIBCD1 fibrinogen C domain containing 1 2.65208
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A 2.56823
PTCH1 patched 1 2.55882
ZNF609 zinc finger protein 609 2.51802
DUSP4 dual specificity phosphatase 4 2.50652
ZFAND2B zinc finger, AN1-type domain 2B 2.49283
PDLIM5 PDZ and LIM domain 5 2.47442
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa 2.44934
UBTD2 ubiquitin domain containing 2 2.38877
ACTN1 actinin, alpha 1 2.35728
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like 2.35478
NRTN neurturin 2.35465
ZNF324 zinc finger protein 324 2.3283
CCL17 chemokine (C-C motif) ligand 17 2.29851
FBXO34 F-box protein 34 2.29436
SREK1 splicing regulatory glutamine/lysine-rich protein 1 2.28051
SLC52A2 solute carrier family 52 (riboflavin transporter), member 2 2.27878
SLC25A42 solute carrier family 25, member 42 2.25283
RPH3A rabphilin 3A 2.25036
PDE11A phosphodiesterase 11A 2.24724
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 2.23562
ESAM endothelial cell adhesion molecule 2.2315
RPRML reprimo-like 2.18582
BSG basigin (Ok blood group) 2.18516
LAMP1 lysosomal-associated membrane protein 1 2.18094
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 2.17818
ACVR1 activin A receptor, type I 2.17091
SCAF4 SR-related CTD-associated factor 4 2.13402
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit 2.12931
CIRBP cold inducible RNA binding protein 2.11866
SMAD7 SMAD family member 7 2.1157
ZNF219 zinc finger protein 219 2.11224
UBIAD1 UbiA prenyltransferase domain containing 1 2.10703
RAB34 RAB34, member RAS oncogene family 2.08894
TTL tubulin tyrosine ligase 2.0878
RBP2 retinol binding protein 2, cellular 2.08517
ZMYM1 zinc finger, MYM-type 1 2.0841
PDXP pyridoxal (pyridoxine, vitamin B6) phosphatase 2.07544
NPEPPS aminopeptidase puromycin sensitive 2.07221
CTTN cortactin 2.07208
HSBP1 heat shock factor binding protein 1 2.05904
POLL polymerase (DNA directed), lambda 2.05831
ZNF574 zinc finger protein 574 2.05464
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 2.05239
ZC3H14 zinc finger CCCH-type containing 14 2.05033
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 2.02607
BCL2L1 BCL2-like 1 2.02583
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 2.02114
RRAS2 related RAS viral (r-ras) oncogene homolog 2 2.01679
ADRB2 adrenoceptor beta 2, surface 2.01267
B3GAT3 beta-1,3-glucuronyltransferase 3 2.00917
CREBL2 cAMP responsive element binding protein-like 2 2.00903
LTBP3 latent transforming growth factor beta binding protein 3 1.98788
SETD2 SET domain containing 2 1.98298
MED16 mediator complex subunit 16 1.97192
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled 1.96461
CTSS cathepsin S 1.96187
HYAL2 hyaluronoglucosaminidase 2 1.95717
GAPVD1 GTPase activating protein and VPS9 domains 1 1.94933
TBC1D10A TBC1 domain family, member 10A 1.94884
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 1.94856
REXO1 REX1, RNA exonuclease 1 homolog (S. cerevisiae) 1.94773
TEF thyrotrophic embryonic factor 1.94275
RABGGTA Rab geranylgeranyltransferase, alpha subunit 1.94223
NEU1 sialidase 1 (lysosomal sialidase) 1.93859
HARS histidyl-tRNA synthetase 1.93132
EPHA3 EPH receptor A3 1.93082
PCCB propionyl CoA carboxylase, beta polypeptide 1.92859
PRMT3 protein arginine methyltransferase 3 1.91384
ADCY6 adenylate cyclase 6 1.90454
PSMG2 proteasome (prosome, macropain) assembly chaperone 2 1.90296
VEZF1 vascular endothelial zinc finger 1 1.8984
MMP24 matrix metallopeptidase 24 (membrane-inserted) 1.89224
E2F6 E2F transcription factor 6 1.88998
GLRB glycine receptor, beta 1.88568
RCE1 Ras converting CAAX endopeptidase 1 1.88139
APOA5 apolipoprotein A-V 1.87456
SLC39A4 solute carrier family 39 (zinc transporter), member 4 1.87415
AURKAIP1 aurora kinase A interacting protein 1 1.86093
TEAD3 TEA domain family member 3 1.85837
SPATA9 spermatogenesis associated 9 1.85659
COMMD5 COMM domain containing 5 1.85153
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) 1.84813
SLC35A4 solute carrier family 35, member A4 1.8379
COX18 COX18 cytochrome c oxidase assembly factor 1.83264
SVIL supervillin 1.83159
LRRC23 leucine rich repeat containing 23 1.82876
ZNF703 zinc finger protein 703 1.82472
AMPD2 adenosine monophosphate deaminase 2 1.82443
NR2C1 nuclear receptor subfamily 2, group C, member 1 1.82355
TOR2A torsin family 2, member A 1.81916
RAB40C RAB40C, member RAS oncogene family 1.817
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa 1.81592
PCSK6 proprotein convertase subtilisin/kexin type 6 1.81496
DUSP5 dual specificity phosphatase 5 1.81371
CSF1R colony stimulating factor 1 receptor 1.81208
IFI30 interferon, gamma-inducible protein 30 1.80427
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) 1.79951
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 1.79482
SPNS1 spinster homolog 1 (Drosophila) 1.78876
PTPRA protein tyrosine phosphatase, receptor type, A 1.78447
TMEM91 transmembrane protein 91 1.77977
SRF serum response factor (c-fos serum response element-binding transcription factor) 1.76511
MRPL53 mitochondrial ribosomal protein L53 1.76039
ACTL7B actin-like 7B 1.74877
PET100 PET100 homolog (S. cerevisiae) 1.74819
OSBPL2 oxysterol binding protein-like 2 1.74673
GINM1 glycoprotein integral membrane 1 1.74654
TRIM9 tripartite motif containing 9 1.74591
PRDX2 peroxiredoxin 2 1.74589
FZD2 frizzled class receptor 2 1.74395
CYTH2 cytohesin 2 1.74078
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 1.73979
SERTAD2 SERTA domain containing 2 1.7317
AKT1S1 AKT1 substrate 1 (proline-rich) 1.73137
NEURL2 neuralized E3 ubiquitin protein ligase 2 1.73063
PNRC2 proline-rich nuclear receptor coactivator 2 1.72515
PRR12 proline rich 12 1.72355
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 1.7217
FAM134A family with sequence similarity 134, member A 1.71952
NOA1 nitric oxide associated 1 1.71906
RPL7A ribosomal protein L7a 1.7144
PAPD7 PAP associated domain containing 7 1.71288
MAML1 mastermind-like 1 (Drosophila) 1.71148
BCL10 B-cell CLL/lymphoma 10 1.70453
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.70411
SOCS1 suppressor of cytokine signaling 1 1.70077
MAMDC4 MAM domain containing 4 1.70053
SLC7A6OS solute carrier family 7, member 6 opposite strand 1.69281
PRMT6 protein arginine methyltransferase 6 1.69141
SQSTM1 sequestosome 1 1.691
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) 1.68575
ESR2 estrogen receptor 2 (ER beta) 1.68238
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 1.67458
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 1.67118
HNMT histamine N-methyltransferase 1.66969
PYCR2 pyrroline-5-carboxylate reductase family, member 2 1.66236
WBP2 WW domain binding protein 2 1.66089
ACSM3 acyl-CoA synthetase medium-chain family member 3 1.65817
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1 1.6528
NUP133 nucleoporin 133kDa 1.65235
PHF23 PHD finger protein 23 1.65208
PKD1 polycystic kidney disease 1 (autosomal dominant) 1.65121
PNPO pyridoxamine 5'-phosphate oxidase 1.64845
TPD52L2 tumor protein D52-like 2 1.64695
CDCA4 cell division cycle associated 4 1.64585
BRPF1 bromodomain and PHD finger containing, 1 1.64513
IFT27 intraflagellar transport 27 1.64326
OSGEP O-sialoglycoprotein endopeptidase 1.63016
PPP2R5D protein phosphatase 2, regulatory subunit B', delta 1.62806
UTS2 urotensin 2 1.62733
SH3GLB2 SH3-domain GRB2-like endophilin B2 1.62061
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase 1.61888
MYD88 myeloid differentiation primary response 88 1.61185
VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae) 1.61037
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) 1.60956
ZNF513 zinc finger protein 513 1.60603
PTH2R parathyroid hormone 2 receptor 1.60385
PPP1R9A protein phosphatase 1, regulatory subunit 9A 1.60346
PRDM2 PR domain containing 2, with ZNF domain 1.60124
TARBP2 TAR (HIV-1) RNA binding protein 2 1.60045
CINP cyclin-dependent kinase 2 interacting protein 1.59903
ERCC1 excision repair cross-complementation group 1 1.5957
AKR1D1 aldo-keto reductase family 1, member D1 1.593
AMDHD2 amidohydrolase domain containing 2 1.59155
FOXD1 forkhead box D1 1.59008
PPT1 palmitoyl-protein thioesterase 1 1.57568
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.57493
ITM2B integral membrane protein 2B 1.57088
UGCG UDP-glucose ceramide glucosyltransferase 1.57034
MAX MYC associated factor X 1.56622
ACO2 aconitase 2, mitochondrial 1.56502
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa 1.56113
LPAR3 lysophosphatidic acid receptor 3 1.56067
PBLD phenazine biosynthesis-like protein domain containing 1.55773
RGL2 ral guanine nucleotide dissociation stimulator-like 2 1.55684
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 1.55561
CKLF chemokine-like factor 1.5541
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.55131
MT-ND4 NADH dehydrogenase, subunit 4 (complex I) 1.54953
FGF8 fibroblast growth factor 8 (androgen-induced) 1.54664
RPL15 ribosomal protein L15 1.54318
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 1.54267
MEAF6 MYST/Esa1-associated factor 6 1.54069
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K 1.53849
RAB1B RAB1B, member RAS oncogene family 1.537
PPME1 protein phosphatase methylesterase 1 1.53658
TMEM204 transmembrane protein 204 1.53545
SORCS3 sortilin-related VPS10 domain containing receptor 3 1.53504
CDC34 cell division cycle 34 1.52882
ADAM23 ADAM metallopeptidase domain 23 1.52869
TTI2 TELO2 interacting protein 2 1.5248
ZNF787 zinc finger protein 787 1.52418
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 1.52261
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 1.52159
IPO7 importin 7 1.52155
MAP3K3 mitogen-activated protein kinase kinase kinase 3 1.52029
GMPPA GDP-mannose pyrophosphorylase A 1.51947
CDK10 cyclin-dependent kinase 10 1.5182
ZGPAT zinc finger, CCCH-type with G patch domain 1.51813
PROKR1 prokineticin receptor 1 1.51754
GPN2 GPN-loop GTPase 2 1.51589
ANXA3 annexin A3 1.51159
LRRC49 leucine rich repeat containing 49 1.50839
YLPM1 YLP motif containing 1 1.50559
UBE4B ubiquitination factor E4B 1.50427
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 1.50391
CORO1B coronin, actin binding protein, 1B 1.50161
SNAP91 synaptosomal-associated protein, 91kDa 1.49797
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 1.4949
PRMT5 protein arginine methyltransferase 5 1.49202
IMP4 IMP4, U3 small nucleolar ribonucleoprotein 1.48837
TRAF4 TNF receptor-associated factor 4 1.48649
KLK8 kallikrein-related peptidase 8 1.48557
MTFP1 mitochondrial fission process 1 1.4845
ARHGAP1 Rho GTPase activating protein 1 1.48149
IL1R1 interleukin 1 receptor, type I 1.4795
PRR14 proline rich 14 1.47816
ECH1 enoyl CoA hydratase 1, peroxisomal 1.47807
ENGASE endo-beta-N-acetylglucosaminidase 1.47598
ECSIT ECSIT signalling integrator 1.47458
ADCY10 adenylate cyclase 10 (soluble) 1.47071
ZNF524 zinc finger protein 524 1.47019
GALR3 galanin receptor 3 1.46963
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.45837
STIM1 stromal interaction molecule 1 1.44989
PLEC plectin 1.4494
TSPAN4 tetraspanin 4 1.44865
KISS1R KISS1 receptor 1.44861
NEB nebulin 1.44824
BCAS3 breast carcinoma amplified sequence 3 1.44796
TOR1B torsin family 1, member B (torsin B) 1.44613
FGFR1 fibroblast growth factor receptor 1 1.44204
HRASLS5 HRAS-like suppressor family, member 5 1.44198
RBPJ recombination signal binding protein for immunoglobulin kappa J region 1.4379
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.43735
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa 1.43551
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.43224
CNRIP1 cannabinoid receptor interacting protein 1 1.43163
PDCD2L programmed cell death 2-like 1.42637
CTSZ cathepsin Z 1.42532
JDP2 Jun dimerization protein 2 1.42397
COLGALT1 collagen beta(1-O)galactosyltransferase 1 1.42116
NOB1 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) 1.42028
TST thiosulfate sulfurtransferase (rhodanese) 1.41976
TYROBP TYRO protein tyrosine kinase binding protein 1.41855
TXN thioredoxin 1.41805
PLD3 phospholipase D family, member 3 1.41799
CACNB3 calcium channel, voltage-dependent, beta 3 subunit 1.41356
PHF12 PHD finger protein 12 1.41312
TMUB2 transmembrane and ubiquitin-like domain containing 2 1.41299
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 1.41282
SKAP2 src kinase associated phosphoprotein 2 1.41256
MBTPS1 membrane-bound transcription factor peptidase, site 1 1.41151
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.41007
MRPL3 mitochondrial ribosomal protein L3 1.40849
BCL2L2 BCL2-like 2 1.40175
ENDOG endonuclease G 1.40091
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 1.39915
ANKRD54 ankyrin repeat domain 54 1.39665
BCAR1 breast cancer anti-estrogen resistance 1 1.39311
PCSK7 proprotein convertase subtilisin/kexin type 7 1.39199
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 1.39145
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.38934
TTC7B tetratricopeptide repeat domain 7B 1.38927
SNX18 sorting nexin 18 1.38884
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 1.38866
SERTAD1 SERTA domain containing 1 1.38798
GPSM1 G-protein signaling modulator 1 1.38764
ZBTB2 zinc finger and BTB domain containing 2 1.38718
HELLS helicase, lymphoid-specific 1.38529
PRKCZ protein kinase C, zeta 1.38472
UBD ubiquitin D 1.38314
SERBP1 SERPINE1 mRNA binding protein 1 1.38161
PLCE1 phospholipase C, epsilon 1 1.37596
CTSD cathepsin D 1.37546
PSD pleckstrin and Sec7 domain containing 1.37296
GAMT guanidinoacetate N-methyltransferase 1.37257
ADRM1 adhesion regulating molecule 1 1.37236
APLP1 amyloid beta (A4) precursor-like protein 1 1.37057
CDKN2A cyclin-dependent kinase inhibitor 2A 1.36566
RNASEH1 ribonuclease H1 1.36379
CYBA cytochrome b-245, alpha polypeptide 1.3621
TIMP3 TIMP metallopeptidase inhibitor 3 1.35805
CABLES2 Cdk5 and Abl enzyme substrate 2 1.35612
ZNF746 zinc finger protein 746 1.3546
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 1.35407
RABEP2 rabaptin, RAB GTPase binding effector protein 2 1.35407
TRIM8 tripartite motif containing 8 1.35279
TCTA T-cell leukemia translocation altered 1.35091
SIRT6 sirtuin 6 1.34942
KDM8 lysine (K)-specific demethylase 8 1.34802

decreased expression

Symbol Name Standardized Value
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -3.85651
TMEM194B transmembrane protein 194B -3.3581
TERF2 telomeric repeat binding factor 2 -3.24296
RGS7BP regulator of G-protein signaling 7 binding protein -3.1723
CRLF3 cytokine receptor-like factor 3 -3.1416
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 -3.1387
CDK4 cyclin-dependent kinase 4 -3.12316
SAP130 Sin3A-associated protein, 130kDa -3.09241
ALG8 ALG8, alpha-1,3-glucosyltransferase -3.03939
BARD1 BRCA1 associated RING domain 1 -3.03365
TBKBP1 TBK1 binding protein 1 -3.00773
DIS3L2 DIS3 like 3'-5' exoribonuclease 2 -2.9527
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 -2.92547
RFC4 replication factor C (activator 1) 4, 37kDa -2.92545
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 -2.89313
INHBA inhibin, beta A -2.8614
MRFAP1 Morf4 family associated protein 1 -2.83468
MTO1 mitochondrial tRNA translation optimization 1 -2.82502
SLC45A3 solute carrier family 45, member 3 -2.78383
PPP1R3D protein phosphatase 1, regulatory subunit 3D -2.76132
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -2.68713
SH3BGRL2 SH3 domain binding glutamate-rich protein like 2 -2.62908
KRT12 keratin 12, type I -2.60022
CHMP6 charged multivesicular body protein 6 -2.55483
ALDH18A1 aldehyde dehydrogenase 18 family, member A1 -2.54832
RNF213 ring finger protein 213 -2.50305
CNBP CCHC-type zinc finger, nucleic acid binding protein -2.42942
CA5B carbonic anhydrase VB, mitochondrial -2.41126
TNPO3 transportin 3 -2.40793
BAZ1B bromodomain adjacent to zinc finger domain, 1B -2.39785
ACVRL1 activin A receptor type II-like 1 -2.3969
COX1 -2.39505
MC4R melanocortin 4 receptor -2.37703
TCF4 transcription factor 4 -2.37353
ANKRD10 ankyrin repeat domain 10 -2.36679
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 -2.36052
L3HYPDH L-3-hydroxyproline dehydratase (trans-) -2.35169
TRMT5 tRNA methyltransferase 5 -2.33661
DIO2 deiodinase, iodothyronine, type II -2.33191
SCN7A sodium channel, voltage gated, type VII alpha subunit -2.29593
NHP2 NHP2 ribonucleoprotein -2.28848
MPI mannose phosphate isomerase -2.27882
ACTR3 ARP3 actin-related protein 3 homolog (yeast) -2.26726
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled -2.26385
CD80 CD80 molecule -2.2611
TRIP10 thyroid hormone receptor interactor 10 -2.24963
CLASP1 cytoplasmic linker associated protein 1 -2.22577
TMA16 translation machinery associated 16 homolog (S. cerevisiae) -2.22072
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -2.21787
ANKRD23 ankyrin repeat domain 23 -2.2111
HSPA12A heat shock 70kDa protein 12A -2.20562
TPST1 tyrosylprotein sulfotransferase 1 -2.18006
SSRP1 structure specific recognition protein 1 -2.17104
ENO2 enolase 2 (gamma, neuronal) -2.16883
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) -2.16834
EFHD1 EF-hand domain family, member D1 -2.16765
ARL5C ADP-ribosylation factor-like 5C -2.16211
PLRG1 pleiotropic regulator 1 -2.1207
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -2.10844
KCTD10 potassium channel tetramerization domain containing 10 -2.10654
FAM43A family with sequence similarity 43, member A -2.10371
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2 -2.10078
PKIB protein kinase (cAMP-dependent, catalytic) inhibitor beta -2.09982
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) -2.09918
IQUB IQ motif and ubiquitin domain containing -2.09425
PRIM1 primase, DNA, polypeptide 1 (49kDa) -2.08994
MT-ND3 NADH dehydrogenase, subunit 3 (complex I) -2.08969
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial -2.08024
GALK1 galactokinase 1 -2.07827
C1QTNF3 C1q and tumor necrosis factor related protein 3 -2.06767
CSK c-src tyrosine kinase -2.06224
NKD1 naked cuticle homolog 1 (Drosophila) -2.0576
TMEM87A transmembrane protein 87A -2.05721
SRD5A3 steroid 5 alpha-reductase 3 -2.04025
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) -2.03436
LPCAT3 lysophosphatidylcholine acyltransferase 3 -2.0227
DOCK8 dedicator of cytokinesis 8 -2.00864
PTER phosphotriesterase related -2.00482
RPS9 ribosomal protein S9 -2.00351
RHOC ras homolog family member C -2.00131
MYO9B myosin IXB -1.98477
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein -1.98451
CKAP5 cytoskeleton associated protein 5 -1.97509
RPS4Y1 ribosomal protein S4, Y-linked 1 -1.97098
RPL26 ribosomal protein L26 -1.9602
KLRD1 killer cell lectin-like receptor subfamily D, member 1 -1.95618
RBPMS RNA binding protein with multiple splicing -1.95294
DMPK dystrophia myotonica-protein kinase -1.94893
DSCC1 DNA replication and sister chromatid cohesion 1 -1.9383
TBRG4 transforming growth factor beta regulator 4 -1.92893
COL10A1 collagen, type X, alpha 1 -1.92887
RARS arginyl-tRNA synthetase -1.92696
GRIPAP1 GRIP1 associated protein 1 -1.92333
DGKB diacylglycerol kinase, beta 90kDa -1.92099
NOTCH2 notch 2 -1.91912
MLF2 myeloid leukemia factor 2 -1.91787
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2 -1.91771
PREPL prolyl endopeptidase-like -1.91501
PLD2 phospholipase D2 -1.90996
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae) -1.90183
GALC galactosylceramidase -1.89911
TAGLN2 transgelin 2 -1.89587
CAPG capping protein (actin filament), gelsolin-like -1.89506
BARHL1 BarH-like homeobox 1 -1.89494
AES amino-terminal enhancer of split -1.89026
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A -1.86836
PLD1 phospholipase D1, phosphatidylcholine-specific -1.8588
FGFBP3 fibroblast growth factor binding protein 3 -1.8546
LITAF lipopolysaccharide-induced TNF factor -1.85428
RAP1A RAP1A, member of RAS oncogene family -1.84943
NVL nuclear VCP-like -1.84749
CAV1 caveolin 1, caveolae protein, 22kDa -1.84256
CRYAB crystallin, alpha B -1.84071
UFL1 UFM1-specific ligase 1 -1.83884
HDGFRP3 hepatoma-derived growth factor, related protein 3 -1.83802
OPRK1 opioid receptor, kappa 1 -1.83714
ZBED3 zinc finger, BED-type containing 3 -1.83596
BCAT2 branched chain amino-acid transaminase 2, mitochondrial -1.83521
PLEKHA5 pleckstrin homology domain containing, family A member 5 -1.83353
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha -1.82871
CELF2 CUGBP, Elav-like family member 2 -1.82588
GRB2 growth factor receptor-bound protein 2 -1.81996
PPP2R1B protein phosphatase 2, regulatory subunit A, beta -1.813
SP110 SP110 nuclear body protein -1.81118
SRSF1 serine/arginine-rich splicing factor 1 -1.81068
SHANK2 SH3 and multiple ankyrin repeat domains 2 -1.80989
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 -1.80758
CELF5 CUGBP, Elav-like family member 5 -1.7992
MEMO1 mediator of cell motility 1 -1.7896
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3 -1.78514
LINGO2 leucine rich repeat and Ig domain containing 2 -1.78027
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like -1.77279
FAM57B family with sequence similarity 57, member B -1.76913
RTN3 reticulon 3 -1.769
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) -1.76645
SEPW1 selenoprotein W, 1 -1.76105
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae) -1.75432
MEF2C myocyte enhancer factor 2C -1.7531
COMMD2 COMM domain containing 2 -1.7499
USP19 ubiquitin specific peptidase 19 -1.74904
FABP1 fatty acid binding protein 1, liver -1.74402
ZFHX2 zinc finger homeobox 2 -1.74359
PLXNB2 plexin B2 -1.74215
TMEM110-MUSTN1 TMEM110-MUSTN1 readthrough -1.74042
TMX2 thioredoxin-related transmembrane protein 2 -1.72833
FGB fibrinogen beta chain -1.71967
FAM214B family with sequence similarity 214, member B -1.7075
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa -1.70645
PGRMC2 progesterone receptor membrane component 2 -1.70154
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 -1.70123
TMEM246 transmembrane protein 246 -1.69979
CXCL13 chemokine (C-X-C motif) ligand 13 -1.69967
ZEB1 zinc finger E-box binding homeobox 1 -1.69133
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -1.69025
HMP19 HMP19 protein -1.68461
FLNB filamin B, beta -1.68126
FBXW8 F-box and WD repeat domain containing 8 -1.68073
MNAT1 MNAT CDK-activating kinase assembly factor 1 -1.67492
HOPX HOP homeobox -1.67426
MFN1 mitofusin 1 -1.67387
MFAP5 microfibrillar associated protein 5 -1.67276
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic) -1.67267
STK38 serine/threonine kinase 38 -1.67241
IL15 interleukin 15 -1.67174
KDM1A lysine (K)-specific demethylase 1A -1.66985
RFC2 replication factor C (activator 1) 2, 40kDa -1.66907
HOMER2 homer scaffolding protein 2 -1.66674
RPL14 ribosomal protein L14 -1.66651
ACBD3 acyl-CoA binding domain containing 3 -1.66393
CCNB1 cyclin B1 -1.66262
DHRS7B dehydrogenase/reductase (SDR family) member 7B -1.65988
SMC5 structural maintenance of chromosomes 5 -1.65663
STMN2 stathmin 2 -1.65313
SYT2 synaptotagmin II -1.65232
PCED1B PC-esterase domain containing 1B -1.65043
ATP1B4 ATPase, Na+/K+ transporting, beta 4 polypeptide -1.65005
CXCR3 chemokine (C-X-C motif) receptor 3 -1.64972
ZSWIM7 zinc finger, SWIM-type containing 7 -1.6475
NCK2 NCK adaptor protein 2 -1.64561
TREH trehalase (brush-border membrane glycoprotein) -1.64463
POLR3B polymerase (RNA) III (DNA directed) polypeptide B -1.64236
SPRYD3 SPRY domain containing 3 -1.64049
BRCA2 breast cancer 2, early onset -1.63136
FAM84A family with sequence similarity 84, member A -1.62818
CRHBP corticotropin releasing hormone binding protein -1.62748
PLK4 polo-like kinase 4 -1.62413
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -1.62345
IL1R2 interleukin 1 receptor, type II -1.61804
ARMCX2 armadillo repeat containing, X-linked 2 -1.61745
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -1.61668
STXBP5 syntaxin binding protein 5 (tomosyn) -1.61229
MRPL46 mitochondrial ribosomal protein L46 -1.61154
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 -1.61035
RIN2 Ras and Rab interactor 2 -1.60838
MGST1 microsomal glutathione S-transferase 1 -1.60756
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2 -1.60734
DDR2 discoidin domain receptor tyrosine kinase 2 -1.60152
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 -1.59694
SAP30BP SAP30 binding protein -1.59464
EHBP1 EH domain binding protein 1 -1.59446
MPPED1 metallophosphoesterase domain containing 1 -1.59289
CNR2 cannabinoid receptor 2 (macrophage) -1.5865
SYT11 synaptotagmin XI -1.58407
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit -1.58275
AIF1 allograft inflammatory factor 1 -1.58255
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -1.58173
CABIN1 calcineurin binding protein 1 -1.57965
CCNT2 cyclin T2 -1.57846
RPL5 ribosomal protein L5 -1.57741
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 -1.57687
IRAK1BP1 interleukin-1 receptor-associated kinase 1 binding protein 1 -1.57659
PRPF38A pre-mRNA processing factor 38A -1.57604
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 -1.57341
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 -1.57151
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24 -1.57118
ANAPC1 anaphase promoting complex subunit 1 -1.56985
CALCR calcitonin receptor -1.56619
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 -1.55884
BTBD2 BTB (POZ) domain containing 2 -1.55216
CCNY cyclin Y -1.5488
ARL15 ADP-ribosylation factor-like 15 -1.54859
GLMN glomulin, FKBP associated protein -1.5463
MCM3 minichromosome maintenance complex component 3 -1.54613
SEC16A SEC16 homolog A (S. cerevisiae) -1.54555
PRKCE protein kinase C, epsilon -1.54279
BCL2L12 BCL2-like 12 (proline rich) -1.54253
ZNF613 zinc finger protein 613 -1.54249
ZNF519 zinc finger protein 519 -1.5387
ASF1B anti-silencing function 1B histone chaperone -1.53841
LBH limb bud and heart development -1.53814
STAR steroidogenic acute regulatory protein -1.53228
ATXN7L3B ataxin 7-like 3B -1.53155
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) -1.52794
RAD51AP1 RAD51 associated protein 1 -1.52743
RPRM reprimo, TP53 dependent G2 arrest mediator candidate -1.52299
PDGFRB platelet-derived growth factor receptor, beta polypeptide -1.522
FAM45A family with sequence similarity 45, member A -1.52039
DPF1 D4, zinc and double PHD fingers family 1 -1.51752
FAM58A family with sequence similarity 58, member A -1.51649
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 -1.5156
RPL8 ribosomal protein L8 -1.50956
VARS valyl-tRNA synthetase -1.50807
TGM2 transglutaminase 2 -1.50759
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3 -1.50735
PLIN2 perilipin 2 -1.49904
UBQLN2 ubiquilin 2 -1.49692
NUP93 nucleoporin 93kDa -1.49574
CX3CL1 chemokine (C-X3-C motif) ligand 1 -1.49422
MT-CYB cytochrome b -1.49199
SSNA1 Sjogren syndrome nuclear autoantigen 1 -1.49112
SAMM50 SAMM50 sorting and assembly machinery component -1.48987
LUM lumican -1.48949
NR4A1 nuclear receptor subfamily 4, group A, member 1 -1.4867
DBNL drebrin-like -1.48409
EXOC7 exocyst complex component 7 -1.48331
EVI2A ecotropic viral integration site 2A -1.48257
DCTPP1 dCTP pyrophosphatase 1 -1.47952
PTPN14 protein tyrosine phosphatase, non-receptor type 14 -1.47928
GAB1 GRB2-associated binding protein 1 -1.47748
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa -1.47666
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 -1.47586
LIMS1 LIM and senescent cell antigen-like domains 1 -1.47527
FOSL1 FOS-like antigen 1 -1.47453
ANO6 anoctamin 6 -1.47379
NT5E 5'-nucleotidase, ecto (CD73) -1.47095
PADI3 peptidyl arginine deiminase, type III -1.46705
ITPK1 inositol-tetrakisphosphate 1-kinase -1.46647
SNX1 sorting nexin 1 -1.46562
TRPM3 transient receptor potential cation channel, subfamily M, member 3 -1.46398
STK16 serine/threonine kinase 16 -1.46327
WNT5A wingless-type MMTV integration site family, member 5A -1.46085
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 -1.45881
WBP5 WW domain binding protein 5 -1.45709
OSBP oxysterol binding protein -1.45674
SCNN1A sodium channel, non voltage gated 1 alpha subunit -1.45655
EME2 essential meiotic structure-specific endonuclease subunit 2 -1.45557
KIF5C kinesin family member 5C -1.4536
AFM afamin -1.45096
ABT1 activator of basal transcription 1 -1.44868
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 -1.44204
SYCP1 synaptonemal complex protein 1 -1.4386
TMEM101 transmembrane protein 101 -1.43804
SPTA1 spectrin, alpha, erythrocytic 1 -1.43733
TRMT6 tRNA methyltransferase 6 -1.43712
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) -1.43396
HSPD1 heat shock 60kDa protein 1 (chaperonin) -1.43348
POLR1E polymerase (RNA) I polypeptide E, 53kDa -1.43267
MDM1 Mdm1 nuclear protein homolog (mouse) -1.43248
CTC1 CTS telomere maintenance complex component 1 -1.4323
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 -1.42775
GABRG1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 -1.42381
RRM1 ribonucleotide reductase M1 -1.42371
MYBPC1 myosin binding protein C, slow type -1.42363
SPINT2 serine peptidase inhibitor, Kunitz type, 2 -1.41534
CRLF2 cytokine receptor-like factor 2 -1.41481
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) -1.41444
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 -1.4093
FUNDC2 FUN14 domain containing 2 -1.40882
RIMS2 regulating synaptic membrane exocytosis 2 -1.4078
PALM paralemmin -1.40763
Funding