| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idoxuridine perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Idoxuridine_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.286352 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.224215 |
| ENO1 | enolase 1, (alpha) | 0.130353 |
| FN1 | fibronectin 1 | 0.128573 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.12462 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.111493 |
| APOB | apolipoprotein B | 0.106765 |
| DSPP | dentin sialophosphoprotein | 0.104264 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0969154 |
| TF | transferrin | 0.0959909 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0817331 |
| GPC3 | glypican 3 | 0.0774924 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0733038 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | 0.0706758 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0685481 |
| SLC38A2 | solute carrier family 38, member 2 | 0.065775 |
| PEG3 | paternally expressed 3 | 0.0648629 |
| LDHA | lactate dehydrogenase A | 0.0633284 |
| AFDN | afadin, adherens junction formation factor | 0.0622835 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0613446 |
| SDC4 | syndecan 4 | 0.0596168 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0593096 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0539746 |
| EHBP1 | EH domain binding protein 1 | 0.0534286 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0530653 |
| RBM39 | RNA binding motif protein 39 | 0.051673 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.050158 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0494837 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0493563 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0488742 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0486426 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0482561 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0479039 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0477871 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0467119 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0448547 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0432254 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0431333 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0423634 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | 0.0403367 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0400305 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0399132 |
| RPL4 | ribosomal protein L4 | 0.0399017 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0391436 |
| DST | dystonin | 0.0389151 |
| UBC | ubiquitin C | 0.0385567 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0369603 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0365565 |
| PCBP2 | poly(rC) binding protein 2 | 0.0363077 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0361957 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0358581 |
| SESTD1 | SEC14 and spectrin domains 1 | 0.03583 |
| AHNAK | AHNAK nucleoprotein | 0.0351112 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0340991 |
| KIF5B | kinesin family member 5B | 0.0340667 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0340087 |
| CFB | complement factor B | 0.0337646 |
| FRMD5 | FERM domain containing 5 | 0.0337003 |
| PGK1 | phosphoglycerate kinase 1 | 0.0333976 |
| JMJD1C | jumonji domain containing 1C | 0.0325681 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0323397 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0323073 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.0322361 |
| PUM2 | pumilio RNA-binding family member 2 | 0.03137 |
| FMNL2 | formin-like 2 | 0.0313022 |
| CANX | calnexin | 0.0312673 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0311994 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | 0.0308484 |
| ASPH | aspartate beta-hydroxylase | 0.0303907 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0302461 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0301769 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0301157 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0297753 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0294929 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0294651 |
| TRIM26 | tripartite motif containing 26 | 0.0293983 |
| RPL26 | ribosomal protein L26 | 0.0286785 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0285637 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.028477 |
| CPE | carboxypeptidase E | 0.0282675 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0282358 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0281531 |
| H1-0 | H1.0 linker histone | 0.028049 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0277249 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0277086 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0276752 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | 0.0276222 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.027484 |
| RPL3 | ribosomal protein L3 | 0.0272626 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0272625 |
| SFTPA2 | surfactant protein A2 | 0.0268247 |
| TMEM123 | transmembrane protein 123 | 0.0267497 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0267137 |
| WDR45B | WD repeat domain 45B | 0.0264482 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0262888 |
| ARFGEF3 | ARFGEF family member 3 | 0.026219 |
| FLNB | filamin B, beta | 0.0255616 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0254255 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0247403 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0246207 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.448385 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.215352 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0953989 |
| C3 | complement component 3 | -0.0650932 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0603356 |
| MT2A | metallothionein 2A | -0.0254739 |
| INTS6 | integrator complex subunit 6 | -0.0242037 |
| EGR1 | early growth response 1 | -0.0224834 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | -0.0212557 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0152412 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.015141 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0130039 |
| RPL28 | ribosomal protein L28 | -0.0124073 |
| RPS15 | ribosomal protein S15 | -0.0118184 |
| RPL35A | ribosomal protein L35a | -0.0116368 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0115789 |
| FOXP1 | forkhead box P1 | -0.0106379 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0104213 |
| RPLP1 | ribosomal protein, large, P1 | -0.010318 |
| GOLGB1 | golgin B1 | -0.010283 |
| APOA2 | apolipoprotein A-II | -0.0100898 |
| TMSB10 | thymosin beta 10 | -0.00999949 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -0.00950281 |
| CEP290 | centrosomal protein 290kDa | -0.00924089 |
| LRP5 | low density lipoprotein receptor-related protein 5 | -0.00859305 |
| TAPBP | TAP binding protein (tapasin) | -0.00858994 |
| RASAL2 | RAS protein activator like 2 | -0.00856626 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.00856323 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.00848929 |
| TBCA | tubulin folding cofactor A | -0.00845645 |
| RPL36 | ribosomal protein L36 | -0.00834543 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 | -0.00831232 |
| CAPNS1 | calpain, small subunit 1 | -0.00816174 |
| IL32 | interleukin 32 | -0.00809881 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.00790187 |
| SUMF1 | sulfatase modifying factor 1 | -0.00789579 |
| SKIL | SKI-like proto-oncogene | -0.00789425 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | -0.00787234 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.00784801 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.00783779 |
| RNF44 | ring finger protein 44 | -0.00779848 |
| ADNP | activity-dependent neuroprotector homeobox | -0.00772112 |
| RPS23 | ribosomal protein S23 | -0.00769324 |
| RSU1 | Ras suppressor protein 1 | -0.00768814 |
| RNASEH2A | ribonuclease H2, subunit A | -0.00767472 |
| NHSL1 | NHS-like 1 | -0.00763427 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.00760011 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | -0.00753698 |
| RPL36AL | ribosomal protein L36a-like | -0.00750762 |
| NABP1 | nucleic acid binding protein 1 | -0.00749858 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.00738373 |
| ENKUR | enkurin, TRPC channel interacting protein | -0.00730831 |
| RPL35 | ribosomal protein L35 | -0.00727301 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.00719389 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.00714455 |
| TLE4 | transducin-like enhancer of split 4 | -0.00709981 |
| TOB2 | transducer of ERBB2, 2 | -0.00686768 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.00666848 |
| SLC30A6 | solute carrier family 30 (zinc transporter), member 6 | -0.0065946 |
| NUCB2 | nucleobindin 2 | -0.00659179 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0065693 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.00653201 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.00653104 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.00652077 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | -0.00650833 |
| BRD2 | bromodomain containing 2 | -0.00647628 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.00646354 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.00644373 |
| KIF2A | kinesin heavy chain member 2A | -0.00636874 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.00631538 |
| DPY30 | dpy-30 homolog (C. elegans) | -0.00630078 |
| HSPB1 | heat shock 27kDa protein 1 | -0.00627715 |
| FKTN | fukutin | -0.00623317 |
| MIPOL1 | mirror-image polydactyly 1 | -0.00613539 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.00612259 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.00608154 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.00605839 |
| EPHA2 | EPH receptor A2 | -0.00601312 |
| SETD1B | SET domain containing 1B | -0.00599065 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0059898 |
| BCAR1 | breast cancer anti-estrogen resistance 1 | -0.00596713 |
| WBP2 | WW domain binding protein 2 | -0.00595006 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.00593267 |
| UBAP1 | ubiquitin associated protein 1 | -0.00591593 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | -0.00591324 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00587912 |
| GPATCH2L | G patch domain containing 2-like | -0.00586185 |
| TOMM7 | translocase of outer mitochondrial membrane 7 homolog (yeast) | -0.00586179 |
| NHEJ1 | nonhomologous end-joining factor 1 | -0.00584965 |
| STXBP4 | syntaxin binding protein 4 | -0.0058431 |
| S100A1 | S100 calcium binding protein A1 | -0.00583575 |
| TRIP11 | thyroid hormone receptor interactor 11 | -0.00582872 |
| SHISA5 | shisa family member 5 | -0.00582259 |
| FOXQ1 | forkhead box Q1 | -0.00577617 |
| RPS19 | ribosomal protein S19 | -0.00576581 |
| EEIG1 | estrogen-induced osteoclastogenesis regulator 1 | -0.00576556 |
| CST3 | cystatin C | -0.00576206 |
| CDKL1 | cyclin-dependent kinase-like 1 (CDC2-related kinase) | -0.00575398 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | -0.0057428 |
| EFHD2 | EF-hand domain family, member D2 | -0.00573943 |
