Idoxuridine_Hs 766T Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Idoxuridine perturbation in Hs 766T cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Idoxuridine_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
AHNAK AHNAK nucleoprotein 0.151869
FLNB filamin B, beta 0.107982
FOXO1 forkhead box O1 0.0775503
MYH9 myosin, heavy chain 9, non-muscle 0.0772138
KRT17 keratin 17, type I 0.0724207
TRIO trio Rho guanine nucleotide exchange factor 0.0701323
MYOF myoferlin 0.0691062
NAMPT nicotinamide phosphoribosyltransferase 0.0644793
ANKRD33B ankyrin repeat domain 33B 0.0613247
SMAD3 SMAD family member 3 0.0611339
CUL4B cullin 4B 0.0564336
FNDC3B fibronectin type III domain containing 3B 0.0558246
CEMIP cell migration inducing protein, hyaluronan binding 0.0525638
OGA O-GlcNAcase 0.0519714
PHLDB2 pleckstrin homology-like domain, family B, member 2 0.0514567
ANLN anillin, actin binding protein 0.0511811
BCL2L1 BCL2-like 1 0.0499294
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0480432
APP amyloid beta (A4) precursor protein 0.0462184
PRELID2 PRELI domain containing 2 0.0456493
KIAA1217 KIAA1217 0.0456435
CLU clusterin 0.0455083
CTNND1 catenin (cadherin-associated protein), delta 1 0.0448376
NCOA3 nuclear receptor coactivator 3 0.0447508
FN1 fibronectin 1 0.0436824
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 0.0433709
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0427333
APLP2 amyloid beta (A4) precursor-like protein 2 0.0424767
ITCH itchy E3 ubiquitin protein ligase 0.0406921
CANX calnexin 0.0406525
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 0.0405975
VCL vinculin 0.0399002
SERINC3 serine incorporator 3 0.0394028
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0391533
RBM39 RNA binding motif protein 39 0.0384537
MBNL2 muscleblind-like splicing regulator 2 0.0375407
COPB1 coatomer protein complex, subunit beta 1 0.0368982
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 0.0367554
MBNL1 muscleblind-like splicing regulator 1 0.0362121
ASPH aspartate beta-hydroxylase 0.0359118
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0358729
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.0349912
PGK1 phosphoglycerate kinase 1 0.0345131
LDHA lactate dehydrogenase A 0.0340214
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.0339437
ARRDC3 arrestin domain containing 3 0.0339043
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0335807
PLEC plectin 0.0333985
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 0.0332181
SLC45A4 solute carrier family 45, member 4 0.0331461
KDM3A lysine (K)-specific demethylase 3A 0.033063
SEPTIN9 septin 9 0.0328835
ANKRD10 ankyrin repeat domain 10 0.0327736
BZW1 basic leucine zipper and W2 domains 1 0.0327271
RNF19B ring finger protein 19B 0.0322417
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.0321671
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0317596
SEC31A SEC31 homolog A (S. cerevisiae) 0.0314461
YBX3 Y box binding protein 3 0.0312363
ARHGAP21 Rho GTPase activating protein 21 0.0303787
ANXA2 annexin A2 0.0303598
ITGA6 integrin, alpha 6 0.0302971
IQGAP1 IQ motif containing GTPase activating protein 1 0.0301071
ENO1 enolase 1, (alpha) 0.0299642
KLF7 Kruppel-like factor 7 (ubiquitous) 0.0297229
DOCK5 dedicator of cytokinesis 5 0.0295813
CAPRIN2 caprin family member 2 0.0295413
KMT2E lysine (K)-specific methyltransferase 2E 0.0292906
CLIC4 chloride intracellular channel 4 0.0292833
CAMK2D calcium/calmodulin-dependent protein kinase II delta 0.0291459
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0285267
KTN1 kinectin 1 (kinesin receptor) 0.0282404
ANO6 anoctamin 6 0.0276911
NEK7 NIMA-related kinase 7 0.0275563
PLAT plasminogen activator, tissue 0.0275039
NRIP1 nuclear receptor interacting protein 1 0.0268501
KRT6A keratin 6A, type II 0.0267768
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 0.0267439
BLCAP bladder cancer associated protein 0.0267371
RAB22A RAB22A, member RAS oncogene family 0.0264466
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 0.0262105
KRT14 keratin 14, type I 0.0260154
UBE2H ubiquitin-conjugating enzyme E2H 0.0259239
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.025515
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0254257
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 0.0253715
USP9X ubiquitin specific peptidase 9, X-linked 0.0253501
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.0252518
PICALM phosphatidylinositol binding clathrin assembly protein 0.0251137
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.0250206
SDC4 syndecan 4 0.0248833
DSCAM Down syndrome cell adhesion molecule 0.0248588
RAB10 RAB10, member RAS oncogene family 0.0246702
FNIP1 folliculin interacting protein 1 0.0245053
KDM6A lysine (K)-specific demethylase 6A 0.0244192
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.0243188
RIN2 Ras and Rab interactor 2 0.0238147
COPA coatomer protein complex, subunit alpha 0.0238119
MINDY2 MINDY lysine 48 deubiquitinase 2 0.023708
FLNA filamin A, alpha 0.0236867

decreased expression

Symbol Name Standardized Value
TIMP3 TIMP metallopeptidase inhibitor 3 -0.197688
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0869877
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 -0.0814125
SLC35F3 solute carrier family 35, member F3 -0.0759489
TMSB10 thymosin beta 10 -0.0736696
RPS6 ribosomal protein S6 -0.061808
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.05915
RPS8 ribosomal protein S8 -0.0520759
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0511497
FTH1 ferritin, heavy polypeptide 1 -0.0510314
S100A11 S100 calcium binding protein A11 -0.0447712
RPS21 ribosomal protein S21 -0.0446466
PPDPF pancreatic progenitor cell differentiation and proliferation factor -0.0440834
IGF2 insulin-like growth factor 2 -0.0439061
RPL35A ribosomal protein L35a -0.0435099
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 -0.0433175
ANO1 anoctamin 1, calcium activated chloride channel -0.0420102
HSPG2 heparan sulfate proteoglycan 2 -0.041701
RPLP2 ribosomal protein, large, P2 -0.0412844
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) -0.040972
SULF2 sulfatase 2 -0.0406478
TPT1 tumor protein, translationally-controlled 1 -0.0405366
ALCAM activated leukocyte cell adhesion molecule -0.0405221
S100A10 S100 calcium binding protein A10 -0.0394951
CALB1 calbindin 1, 28kDa -0.0393216
ABI3BP ABI family, member 3 (NESH) binding protein -0.0390354
IFITM3 interferon induced transmembrane protein 3 -0.0383093
FTL ferritin, light polypeptide -0.0377011
MTSS1 metastasis suppressor 1 -0.0369055
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 -0.0367791
RPS25 ribosomal protein S25 -0.0359625
RPS13 ribosomal protein S13 -0.035797
RPLP1 ribosomal protein, large, P1 -0.0340135
DPYD dihydropyrimidine dehydrogenase -0.0338666
RPL37 ribosomal protein L37 -0.0323748
MBOAT2 membrane bound O-acyltransferase domain containing 2 -0.0323541
PDE4D phosphodiesterase 4D, cAMP-specific -0.0322538
RPS19 ribosomal protein S19 -0.0312127
HMGA1 high mobility group AT-hook 1 -0.031052
S100A9 S100 calcium binding protein A9 -0.0306768
RPS14 ribosomal protein S14 -0.0302482
RPL34 ribosomal protein L34 -0.0299084
CSTB cystatin B (stefin B) -0.0278583
POTEF POTE ankyrin domain family, member F -0.0269907
RPS29 ribosomal protein S29 -0.0262249
KCNK1 potassium channel, two pore domain subfamily K, member 1 -0.0261806
CAV1 caveolin 1, caveolae protein, 22kDa -0.0261713
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 -0.0259425
RPL36 ribosomal protein L36 -0.0257257
RPL35 ribosomal protein L35 -0.0255707
SPINK5 serine peptidase inhibitor, Kazal type 5 -0.0254988
RPL37A ribosomal protein L37a -0.0250521
S100A2 S100 calcium binding protein A2 -0.0247789
RPS3 ribosomal protein S3 -0.0247041
RPL31 ribosomal protein L31 -0.0245485
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.0244749
IFI27 interferon, alpha-inducible protein 27 -0.0244413
GNAS GNAS complex locus -0.0241354
RPS12 ribosomal protein S12 -0.0240316
PCDH1 protocadherin 1 -0.0233976
MT2A metallothionein 2A -0.0226568
LAMA5 laminin, alpha 5 -0.0222004
RPL11 ribosomal protein L11 -0.0221519
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa -0.0220415
ZFP36L1 ZFP36 ring finger protein-like 1 -0.0219264
RPL19 ribosomal protein L19 -0.0218923
RPS27 ribosomal protein S27 -0.0218276
IFI44L interferon-induced protein 44-like -0.0215278
RPL36A ribosomal protein L36a -0.0215094
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.021326
EGR1 early growth response 1 -0.0210869
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 -0.021001
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa -0.0209881
RPL17-C18ORF32 RPL17-C18orf32 readthrough -0.0207958
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0204043
CYB5R3 cytochrome b5 reductase 3 -0.0201695
FOSL1 FOS-like antigen 1 -0.0201608
PODXL podocalyxin-like -0.0201301
RPS23 ribosomal protein S23 -0.0196757
NUCB2 nucleobindin 2 -0.0195526
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.0195506
RPL9 ribosomal protein L9 -0.0195434
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 -0.0194514
ABLIM3 actin binding LIM protein family, member 3 -0.0193899
ZMYND8 zinc finger, MYND-type containing 8 -0.0193765
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 -0.0193611
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 -0.0193189
LMO7 LIM domain 7 -0.0192114
RPL23 ribosomal protein L23 -0.0190492
RPL8 ribosomal protein L8 -0.0188715
RPS17 ribosomal protein S17 -0.0187885
PRSS23 protease, serine, 23 -0.0186613
RABGAP1L RAB GTPase activating protein 1-like -0.0184876
ITGB4 integrin, beta 4 -0.0183409
RPL28 ribosomal protein L28 -0.0183069
WDFY2 WD repeat and FYVE domain containing 2 -0.0181748
F3 coagulation factor III (thromboplastin, tissue factor) -0.0175877
PPARG peroxisome proliferator-activated receptor gamma -0.0173753
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0172403
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 -0.0171618