Idoxuridine_KATO III Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Idoxuridine perturbation in KATO III cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Idoxuridine_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
AHNAK AHNAK nucleoprotein 0.129069
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.112519
EMP1 epithelial membrane protein 1 0.0927699
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0922145
LMO7 LIM domain 7 0.0869652
FGFR2 fibroblast growth factor receptor 2 0.0726445
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0692276
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0659684
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0625245
EIF4A2 eukaryotic translation initiation factor 4A2 0.0607952
ANXA1 annexin A1 0.0579571
AREG amphiregulin 0.0578829
UBC ubiquitin C 0.0571468
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0571063
APLP2 amyloid beta (A4) precursor-like protein 2 0.0546345
DSCAM Down syndrome cell adhesion molecule 0.0538911
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0535331
KRT8 keratin 8, type II 0.0528301
MYH9 myosin, heavy chain 9, non-muscle 0.0527183
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0519195
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 0.0515667
LDHA lactate dehydrogenase A 0.0513931
ITGA6 integrin, alpha 6 0.0510044
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.0506684
EPCAM epithelial cell adhesion molecule 0.0497785
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.0495361
PCBP2 poly(rC) binding protein 2 0.0492655
MBNL2 muscleblind-like splicing regulator 2 0.0490342
EIF1 eukaryotic translation initiation factor 1 0.0485252
ASPH aspartate beta-hydroxylase 0.0481223
DSG2 desmoglein 2 0.0461797
PDIA4 protein disulfide isomerase family A, member 4 0.0451175
DSPP dentin sialophosphoprotein 0.0448598
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0447624
UBE2H ubiquitin-conjugating enzyme E2H 0.0431367
HMGB2 high mobility group box 2 0.0430466
ANLN anillin, actin binding protein 0.0421742
POTEF POTE ankyrin domain family, member F 0.0421479
APP amyloid beta (A4) precursor protein 0.0417239
SEL1L sel-1 suppressor of lin-12-like (C. elegans) 0.0412239
EZR ezrin 0.0410112
CD2AP CD2-associated protein 0.0399095
MACF1 microtubule-actin crosslinking factor 1 0.0392987
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.039181
ADAM9 ADAM metallopeptidase domain 9 0.0376405
ESRP1 epithelial splicing regulatory protein 1 0.0371268
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0364159
AKAP9 A kinase (PRKA) anchor protein 9 0.0360324
MKI67 marker of proliferation Ki-67 0.0353808
KRT19 keratin 19, type I 0.0344949
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0344935
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0336953
TJP1 tight junction protein 1 0.0336493
ANXA2 annexin A2 0.0335013
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.0334297
IQGAP1 IQ motif containing GTPase activating protein 1 0.0319997
ZSWIM6 zinc finger, SWIM-type containing 6 0.0311308
BAIAP2L1 BAI1-associated protein 2-like 1 0.0309608
TMEM45B transmembrane protein 45B 0.0309478
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 0.0306463
QSOX1 quiescin Q6 sulfhydryl oxidase 1 0.0304468
CALR calreticulin 0.0304347
SUN1 Sad1 and UNC84 domain containing 1 0.0300159
XPOT exportin, tRNA 0.0288009
PGK1 phosphoglycerate kinase 1 0.0287926
ENO1 enolase 1, (alpha) 0.0287705
ATXN1 ataxin 1 0.0279082
SFTPA2 surfactant protein A2 0.0274841
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.0274247
TM4SF1 transmembrane 4 L six family member 1 0.0272922
COPB1 coatomer protein complex, subunit beta 1 0.0271189
INSIG1 insulin induced gene 1 0.0261118
LAMC2 laminin, gamma 2 0.0260133
NPEPPS aminopeptidase puromycin sensitive 0.0259739
MUC13 mucin 13, cell surface associated 0.0256676
SEPTIN9 septin 9 0.0255961
MPRIP myosin phosphatase Rho interacting protein 0.025553
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.0253599
TMC5 transmembrane channel-like 5 0.0252316
IFI27 interferon, alpha-inducible protein 27 0.025081
CLDN4 claudin 4 0.0250159
KLF3 Kruppel-like factor 3 (basic) 0.0250069
RAD21 RAD21 homolog (S. pombe) 0.0244068
GDA guanine deaminase 0.0244057
ATF4 activating transcription factor 4 0.0242766
EXT1 exostosin glycosyltransferase 1 0.0242682
ARF4 ADP-ribosylation factor 4 0.0242101
SREBF2 sterol regulatory element binding transcription factor 2 0.0242049
YBX1 Y box binding protein 1 0.0238689
HLA-A major histocompatibility complex, class I, A 0.0238409
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.0236358
CLDN7 claudin 7 0.0235987
LLGL2 lethal giant larvae homolog 2 (Drosophila) 0.0234513
MRFAP1 Morf4 family associated protein 1 0.0234251
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.0233956
PDIA6 protein disulfide isomerase family A, member 6 0.0232701
EIF4H eukaryotic translation initiation factor 4H 0.0231515
RPN2 ribophorin II 0.0231106
RAB10 RAB10, member RAS oncogene family 0.0228584
MYOF myoferlin 0.0228171

decreased expression

Symbol Name Standardized Value
TMSB10 thymosin beta 10 -0.1509
NPSR1 neuropeptide S receptor 1 -0.122647
GMDS GDP-mannose 4,6-dehydratase -0.107989
RPS6 ribosomal protein S6 -0.0737597
MAML2 mastermind-like 2 (Drosophila) -0.0687667
RPL35A ribosomal protein L35a -0.0651968
RPS3 ribosomal protein S3 -0.0527193
RPL23 ribosomal protein L23 -0.0474364
SAMD12 sterile alpha motif domain containing 12 -0.0434098
RPS16 ribosomal protein S16 -0.0421573
RPL34 ribosomal protein L34 -0.0389402
EHBP1 EH domain binding protein 1 -0.0385233
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.0375972
PTMA prothymosin, alpha -0.0360159
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0353192
ACACA acetyl-CoA carboxylase alpha -0.0343127
RPS25 ribosomal protein S25 -0.0341335
RPS8 ribosomal protein S8 -0.0332632
RPLP1 ribosomal protein, large, P1 -0.0326266
PHF14 PHD finger protein 14 -0.0324515
RPL19 ribosomal protein L19 -0.0323746
RPS24 ribosomal protein S24 -0.0321665
S100P S100 calcium binding protein P -0.0320598
RPS27 ribosomal protein S27 -0.0316696
PPARG peroxisome proliferator-activated receptor gamma -0.0311544
RPS29 ribosomal protein S29 -0.0302979
RAD51B RAD51 paralog B -0.0296994
CDK6 cyclin-dependent kinase 6 -0.029274
RPL36 ribosomal protein L36 -0.0292311
RPL38 ribosomal protein L38 -0.0289213
PFN1 profilin 1 -0.0260266
TPT1 tumor protein, translationally-controlled 1 -0.0259177
PPDPF pancreatic progenitor cell differentiation and proliferation factor -0.0258333
RPS19 ribosomal protein S19 -0.0258294
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 -0.0254852
RPL37A ribosomal protein L37a -0.0253442
RPL12 ribosomal protein L12 -0.0251097
RAI1 retinoic acid induced 1 -0.0244946
RPS14 ribosomal protein S14 -0.0244885
FRMD5 FERM domain containing 5 -0.0240792
RPL26 ribosomal protein L26 -0.0235874
IFITM3 interferon induced transmembrane protein 3 -0.0235177
RPS17 ribosomal protein S17 -0.0235113
SLC38A1 solute carrier family 38, member 1 -0.0232285
RPL18 ribosomal protein L18 -0.0229045
EIF5B eukaryotic translation initiation factor 5B -0.022746
TRIM2 tripartite motif containing 2 -0.02271
FTL ferritin, light polypeptide -0.0226082
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.0225739
S100A9 S100 calcium binding protein A9 -0.022553
SEC61G Sec61 gamma subunit -0.0221272
RPS21 ribosomal protein S21 -0.0217622
CEMIP cell migration inducing protein, hyaluronan binding -0.0217237
ATF7IP2 activating transcription factor 7 interacting protein 2 -0.0211946
RPL37 ribosomal protein L37 -0.0209122
RPL35 ribosomal protein L35 -0.0208769
RAB2A RAB2A, member RAS oncogene family -0.020771
TNRC6B trinucleotide repeat containing 6B -0.0206198
RUNX1 runt-related transcription factor 1 -0.0205248
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase -0.0202904
RPL9 ribosomal protein L9 -0.0201091
TBC1D22A TBC1 domain family, member 22A -0.0200167
ARHGAP6 Rho GTPase activating protein 6 -0.0199311
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.0196819
GARS1 glycyl-tRNA synthetase 1 -0.0196249
BRD4 bromodomain containing 4 -0.0195763
SPINT2 serine peptidase inhibitor, Kunitz type, 2 -0.0189783
SSR4 signal sequence receptor, delta -0.0189704
SHROOM3 shroom family member 3 -0.0188356
RNF13 ring finger protein 13 -0.0188147
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0188071
THOC2 THO complex 2 -0.0187875
TMSB4X thymosin beta 4, X-linked -0.0185996
CCND1 cyclin D1 -0.0182297
PALLD palladin, cytoskeletal associated protein -0.0181604
SULF2 sulfatase 2 -0.0181041
ABHD2 abhydrolase domain containing 2 -0.0180581
HMGA1 high mobility group AT-hook 1 -0.017945
CTNND1 catenin (cadherin-associated protein), delta 1 -0.0177737
CHLSN cholesin -0.0177582
RACK1 receptor for activated C kinase 1 -0.0177569
RPL7A ribosomal protein L7a -0.017653
PPIG peptidylprolyl isomerase G (cyclophilin G) -0.0176233
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0175301
RPL31 ribosomal protein L31 -0.0174757
GOLPH3L golgi phosphoprotein 3-like -0.0172144
TMCC1 transmembrane and coiled-coil domain family 1 -0.0171991
TCF12 transcription factor 12 -0.0171003
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 -0.0169989
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) -0.0169454
ABHD17C abhydrolase domain containing 17C -0.0168953
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 -0.0167303
TAS2R14 taste receptor, type 2, member 14 -0.0167098
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0166125
RPL30 ribosomal protein L30 -0.0165728
RPL17-C18ORF32 RPL17-C18orf32 readthrough -0.016538
BTBD9 BTB (POZ) domain containing 9 -0.0164559
COG5 component of oligomeric golgi complex 5 -0.0163563
STAU1 staufen double-stranded RNA binding protein 1 -0.0162807
NIBAN1 niban apoptosis regulator 1 -0.0161188