Idoxuridine_LS 180 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Idoxuridine perturbation in LS 180 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Idoxuridine_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
FAT1 FAT atypical cadherin 1 0.144951
MUC6 mucin 6, oligomeric mucus/gel-forming 0.125979
CEMIP cell migration inducing protein, hyaluronan binding 0.121107
NDRG1 N-myc downstream regulated 1 0.104104
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0895856
AHNAK AHNAK nucleoprotein 0.0876529
LDHA lactate dehydrogenase A 0.0763524
FLNB filamin B, beta 0.0747565
TNS4 tensin 4 0.0747545
KRT8 keratin 8, type II 0.0703374
ITGA6 integrin, alpha 6 0.0701935
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.063217
ABHD2 abhydrolase domain containing 2 0.0613671
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0592908
ASPH aspartate beta-hydroxylase 0.0579833
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.0574694
PPARG peroxisome proliferator-activated receptor gamma 0.0544284
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0525372
POTEF POTE ankyrin domain family, member F 0.0513806
DSPP dentin sialophosphoprotein 0.0507121
CD46 CD46 molecule, complement regulatory protein 0.0503783
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0503776
ANTXR2 anthrax toxin receptor 2 0.0498263
ITPRID2 ITPR interacting domain containing 2 0.0486474
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.048442
KRT19 keratin 19, type I 0.0449826
PCBP2 poly(rC) binding protein 2 0.0446495
ESYT2 extended synaptotagmin-like protein 2 0.0433616
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.0429876
TXNIP thioredoxin interacting protein 0.0429535
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0429049
ENO1 enolase 1, (alpha) 0.0427552
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.0416078
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.0406885
PGK1 phosphoglycerate kinase 1 0.0399698
UBA6 ubiquitin-like modifier activating enzyme 6 0.0387556
CCNY cyclin Y 0.0382524
NPSR1 neuropeptide S receptor 1 0.0381003
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0380819
MACF1 microtubule-actin crosslinking factor 1 0.0380519
PTEN phosphatase and tensin homolog 0.0377893
FAM13A family with sequence similarity 13, member A 0.0368222
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0365176
NALF1 NALCN channel auxiliary factor 1 0.0363562
VEGFA vascular endothelial growth factor A 0.0363052
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.0361364
PSD3 pleckstrin and Sec7 domain containing 3 0.0356829
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0352178
CALB1 calbindin 1, 28kDa 0.0351349
TPM3 tropomyosin 3 0.0345472
KDM4C lysine (K)-specific demethylase 4C 0.0342993
FERMT1 fermitin family member 1 0.0330905
EHF ets homologous factor 0.0330672
ZNF292 zinc finger protein 292 0.032777
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.0324673
PTBP3 polypyrimidine tract binding protein 3 0.0323058
KRT18 keratin 18, type I 0.031818
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.0317471
PTPRR protein tyrosine phosphatase, receptor type, R 0.0314981
KTN1 kinectin 1 (kinesin receptor) 0.0314867
PRELID2 PRELI domain containing 2 0.031054
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 0.0310051
MYH9 myosin, heavy chain 9, non-muscle 0.0306505
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.02985
APLP2 amyloid beta (A4) precursor-like protein 2 0.0294003
KDM7A lysine (K)-specific demethylase 7A 0.0293065
RNF43 ring finger protein 43 0.0286506
MED13L mediator complex subunit 13-like 0.0285544
MCL1 myeloid cell leukemia 1 0.028427
ARHGAP32 Rho GTPase activating protein 32 0.0282024
ANXA11 annexin A11 0.0279112
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0276439
KLF3 Kruppel-like factor 3 (basic) 0.0275141
TBC1D5 TBC1 domain family, member 5 0.0273389
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.0272061
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 0.0271592
UBE2H ubiquitin-conjugating enzyme E2H 0.0269656
ARHGAP26 Rho GTPase activating protein 26 0.0269229
GREB1L growth regulation by estrogen in breast cancer-like 0.0266618
ITGB4 integrin, beta 4 0.0266466
BAZ2B bromodomain adjacent to zinc finger domain, 2B 0.0264403
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0260408
FOSL1 FOS-like antigen 1 0.0260318
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 0.0255063
TM9SF3 transmembrane 9 superfamily member 3 0.0251946
INSIG2 insulin induced gene 2 0.0251347
TPM4 tropomyosin 4 0.0249264
PICALM phosphatidylinositol binding clathrin assembly protein 0.024821
PLAUR plasminogen activator, urokinase receptor 0.0245443
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.0243671
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 0.024346
RPL3 ribosomal protein L3 0.0241777
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0241018
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 0.0239881
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.0237832
PRSS3 protease, serine, 3 0.0236944
MLEC malectin 0.0232687
NCOR2 nuclear receptor corepressor 2 0.0232469
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase 0.022986
FHIT fragile histidine triad 0.0229324

decreased expression

Symbol Name Standardized Value
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.222253
TMSB10 thymosin beta 10 -0.160262
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.132062
TPT1 tumor protein, translationally-controlled 1 -0.100267
RPS6 ribosomal protein S6 -0.0758455
RPLP1 ribosomal protein, large, P1 -0.0749455
RPL34 ribosomal protein L34 -0.0678587
RPS8 ribosomal protein S8 -0.067279
RPL35A ribosomal protein L35a -0.0660651
S100P S100 calcium binding protein P -0.0517921
EIF1 eukaryotic translation initiation factor 1 -0.0492385
RPS19 ribosomal protein S19 -0.0463113
RPS24 ribosomal protein S24 -0.0454012
RPL36 ribosomal protein L36 -0.0453963
RPL26 ribosomal protein L26 -0.0442013
RPL23 ribosomal protein L23 -0.0439416
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.0431163
RPLP2 ribosomal protein, large, P2 -0.043057
GDF15 growth differentiation factor 15 -0.0412383
PTMA prothymosin, alpha -0.0395361
RPL19 ribosomal protein L19 -0.0394396
FTL ferritin, light polypeptide -0.0378192
IARS1 isoleucyl-tRNA synthetase 1 -0.0370227
RPS25 ribosomal protein S25 -0.0367888
ANKRD11 ankyrin repeat domain 11 -0.0339926
LOC112694756 uncharaterized LOC112694756 -0.0337152
RPL31 ribosomal protein L31 -0.0335688
KDM3A lysine (K)-specific demethylase 3A -0.0333598
RPL35 ribosomal protein L35 -0.0331272
RPL32 ribosomal protein L32 -0.0329221
RPL11 ribosomal protein L11 -0.0326583
ISG15 ISG15 ubiquitin-like modifier -0.0320564
RPS3 ribosomal protein S3 -0.031908
RRBP1 ribosome binding protein 1 -0.0317183
RPL37A ribosomal protein L37a -0.0313771
RPS27A ribosomal protein S27a -0.0312643
RPS21 ribosomal protein S21 -0.0309998
GARS1 glycyl-tRNA synthetase 1 -0.0309808
RPS12 ribosomal protein S12 -0.0295055
RPS16 ribosomal protein S16 -0.0294675
RPL28 ribosomal protein L28 -0.0287392
RAB1A RAB1A, member RAS oncogene family -0.0287032
RPS29 ribosomal protein S29 -0.0286964
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.0284205
ARF1 ADP-ribosylation factor 1 -0.0282573
ZFAND3 zinc finger, AN1-type domain 3 -0.0281844
RPL8 ribosomal protein L8 -0.0281814
RPS20 ribosomal protein S20 -0.028155
RPS17 ribosomal protein S17 -0.0278878
RPS14 ribosomal protein S14 -0.0271894
RPL13A ribosomal protein L13a -0.0269707
S100A9 S100 calcium binding protein A9 -0.026767
RTN3 reticulon 3 -0.0265967
ATF4 activating transcription factor 4 -0.0261415
RACK1 receptor for activated C kinase 1 -0.0260332
RPS23 ribosomal protein S23 -0.0260183
RPS2 ribosomal protein S2 -0.0259379
SLC38A2 solute carrier family 38, member 2 -0.0258725
RPL38 ribosomal protein L38 -0.0257643
RPS27 ribosomal protein S27 -0.0257169
AGR2 anterior gradient 2 -0.025234
HMGB1 high mobility group box 1 -0.0252296
RPS5 ribosomal protein S5 -0.0243724
GNAS GNAS complex locus -0.0239996
RPL12 ribosomal protein L12 -0.0238876
MYO1E myosin IE -0.0236038
RPS13 ribosomal protein S13 -0.0234694
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) -0.0232422
RPL14 ribosomal protein L14 -0.0230993
RPL9 ribosomal protein L9 -0.0229523
RPS15 ribosomal protein S15 -0.0227527
H1-0 H1.0 linker histone -0.0227109
NOP58 NOP58 ribonucleoprotein -0.0225042
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -0.0223796
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase -0.0220121
ACTG1 actin gamma 1 -0.0219983
RPL6 ribosomal protein L6 -0.0218436
HDLBP high density lipoprotein binding protein -0.0217504
GOLGA4 golgin A4 -0.0215736
EXT1 exostosin glycosyltransferase 1 -0.0215196
RPLP0 ribosomal protein, large, P0 -0.0212934
KLF5 Kruppel-like factor 5 (intestinal) -0.0211105
RPL17-C18ORF32 RPL17-C18orf32 readthrough -0.0211004
NPR2 natriuretic peptide receptor 2 -0.0208333
RPL37 ribosomal protein L37 -0.0206632
TTC3 tetratricopeptide repeat domain 3 -0.0205507
RAD21 RAD21 homolog (S. pombe) -0.0204239
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0203133
FTH1 ferritin, heavy polypeptide 1 -0.0197681
ANKHD1 ankyrin repeat and KH domain containing 1 -0.0195848
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 -0.0193954
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -0.0193245
FUS FUS RNA binding protein -0.0192254
TXNRD1 thioredoxin reductase 1 -0.018705
RSL1D1 ribosomal L1 domain containing 1 -0.0186675
EIF3E eukaryotic translation initiation factor 3, subunit E -0.0186022
NUPR1 nuclear protein, transcriptional regulator, 1 -0.0184776
KLF6 Kruppel-like factor 6 -0.018291
RPL7A ribosomal protein L7a -0.018124
RPS11 ribosomal protein S11 -0.0178459