| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idoxuridine perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Idoxuridine_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.123566 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.099688 |
| LMO7 | LIM domain 7 | 0.0944665 |
| ASPH | aspartate beta-hydroxylase | 0.0841102 |
| LAMC2 | laminin, gamma 2 | 0.0775044 |
| LDHA | lactate dehydrogenase A | 0.0754999 |
| PGK1 | phosphoglycerate kinase 1 | 0.0595889 |
| PKM | pyruvate kinase, muscle | 0.0579347 |
| ENO1 | enolase 1, (alpha) | 0.0552844 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0536847 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0530914 |
| UBC | ubiquitin C | 0.0493114 |
| AHNAK | AHNAK nucleoprotein | 0.0477495 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0467363 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0457854 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0454202 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0433077 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0423728 |
| PCBP2 | poly(rC) binding protein 2 | 0.04151 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0413968 |
| SPAG9 | sperm associated antigen 9 | 0.0413789 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0413123 |
| LAMA4 | laminin, alpha 4 | 0.0398866 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0394368 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0384331 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0383214 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0372031 |
| DSPP | dentin sialophosphoprotein | 0.0370584 |
| FAM13A | family with sequence similarity 13, member A | 0.0368005 |
| TOP1 | topoisomerase (DNA) I | 0.0353094 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0351332 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0347216 |
| NDRG1 | N-myc downstream regulated 1 | 0.0346005 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0345914 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0344002 |
| STC1 | stanniocalcin 1 | 0.0330773 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0326316 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0324588 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0321228 |
| PTMA | prothymosin, alpha | 0.0314028 |
| LAMB3 | laminin, beta 3 | 0.0313132 |
| KRT18 | keratin 18, type I | 0.0311913 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0311216 |
| ANXA2 | annexin A2 | 0.0310133 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0307469 |
| CANX | calnexin | 0.0306946 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0303483 |
| ACTG1 | actin gamma 1 | 0.030333 |
| TES | testin LIM domain protein | 0.0296299 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0292819 |
| OSMR | oncostatin M receptor | 0.0292304 |
| H1-0 | H1.0 linker histone | 0.028254 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0281676 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0281229 |
| CPE | carboxypeptidase E | 0.0276961 |
| HDLBP | high density lipoprotein binding protein | 0.0275665 |
| TPD52 | tumor protein D52 | 0.0269339 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0260676 |
| USP34 | ubiquitin specific peptidase 34 | 0.0259442 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.025793 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.0254472 |
| OGA | O-GlcNAcase | 0.0253727 |
| JMJD1C | jumonji domain containing 1C | 0.0250425 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0249317 |
| NGLY1 | N-glycanase 1 | 0.0246627 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0242505 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0240808 |
| JAK1 | Janus kinase 1 | 0.0236802 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0235262 |
| MCL1 | myeloid cell leukemia 1 | 0.0234683 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0234254 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.0233377 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0230929 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0230881 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0226808 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.022342 |
| S100A10 | S100 calcium binding protein A10 | 0.0223085 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.022212 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0221158 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0220807 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0219857 |
| ATP13A3 | ATPase type 13A3 | 0.0219107 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0215847 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.021313 |
| ARRDC3 | arrestin domain containing 3 | 0.0212757 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0210906 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.02109 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.0209242 |
| SLC38A1 | solute carrier family 38, member 1 | 0.02092 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0208597 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0208351 |
| YTHDC1 | YTH domain containing 1 | 0.0207901 |
| CES1 | carboxylesterase 1 | 0.0207219 |
| RBM39 | RNA binding motif protein 39 | 0.0205267 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0204282 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0203399 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.020329 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0202731 |
| ANO6 | anoctamin 6 | 0.0202208 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0200422 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.033819 |
| INTS6 | integrator complex subunit 6 | -0.0315086 |
| RPLP1 | ribosomal protein, large, P1 | -0.0255401 |
| RPS3 | ribosomal protein S3 | -0.0198001 |
| RPS12 | ribosomal protein S12 | -0.0179059 |
| RPS27 | ribosomal protein S27 | -0.0174333 |
| S100P | S100 calcium binding protein P | -0.0161204 |
| RPL37A | ribosomal protein L37a | -0.0147349 |
| RPS25 | ribosomal protein S25 | -0.0143033 |
| RPS17 | ribosomal protein S17 | -0.012792 |
| RPS19 | ribosomal protein S19 | -0.0120494 |
| RPL36 | ribosomal protein L36 | -0.011814 |
| RPL35A | ribosomal protein L35a | -0.0114825 |
| HOMER1 | homer scaffolding protein 1 | -0.0111761 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | -0.0108268 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0108208 |
| RPLP2 | ribosomal protein, large, P2 | -0.0107814 |
| RPS23 | ribosomal protein S23 | -0.0105767 |
| LRRC23 | leucine rich repeat containing 23 | -0.00958407 |
| KRT86 | keratin 86, type II | -0.00943357 |
| RPS6 | ribosomal protein S6 | -0.0094313 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.00937317 |
| RACK1 | receptor for activated C kinase 1 | -0.00896884 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.00887058 |
| RPS8 | ribosomal protein S8 | -0.00872886 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.00833184 |
| RPS29 | ribosomal protein S29 | -0.00812696 |
| RPL31 | ribosomal protein L31 | -0.00803587 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.00800831 |
| ANKRD37 | ankyrin repeat domain 37 | -0.00799427 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.00785264 |
| ARMH4 | armadillo like helical domain containing 4 | -0.00773187 |
| FTL | ferritin, light polypeptide | -0.0076582 |
| RPL34 | ribosomal protein L34 | -0.00763184 |
| RPL32 | ribosomal protein L32 | -0.00735286 |
| RPS20 | ribosomal protein S20 | -0.0073361 |
| RPL5 | ribosomal protein L5 | -0.00696832 |
| GUK1 | guanylate kinase 1 | -0.00694399 |
| KDM3B | lysine (K)-specific demethylase 3B | -0.00693137 |
| RPL28 | ribosomal protein L28 | -0.00691608 |
| RPS10 | ribosomal protein S10 | -0.00684955 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.00684792 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.00665595 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.00664015 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.00663897 |
| RPL12 | ribosomal protein L12 | -0.00634955 |
| FAU | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | -0.00627762 |
| IRS2 | insulin receptor substrate 2 | -0.00627571 |
| LRP12 | low density lipoprotein receptor-related protein 12 | -0.00613944 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.00604948 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | -0.00600662 |
| DISC1 | disrupted in schizophrenia 1 | -0.00600151 |
| PER3 | period circadian clock 3 | -0.00593081 |
| RAD51B | RAD51 paralog B | -0.00583573 |
| AEBP2 | AE binding protein 2 | -0.0057876 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.00574639 |
| SERTAD2 | SERTA domain containing 2 | -0.0056685 |
| RPL13A | ribosomal protein L13a | -0.00562582 |
| RPL23 | ribosomal protein L23 | -0.00555654 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.00554768 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.00553509 |
| RPS16 | ribosomal protein S16 | -0.0055185 |
| TMEM184B | transmembrane protein 184B | -0.00551317 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0055117 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -0.00545138 |
| GTF2B | general transcription factor IIB | -0.0054083 |
| BANP | BTG3 associated nuclear protein | -0.00537234 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.00534995 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | -0.00533281 |
| CFAP96 | cilia and flagella associated protein 96 | -0.00531213 |
| SRP19 | signal recognition particle 19kDa | -0.00530254 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | -0.00527477 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.00522653 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.00522424 |
| CDR2 | cerebellar degeneration-related protein 2, 62kDa | -0.00522386 |
| FANK1 | fibronectin type III and ankyrin repeat domains 1 | -0.00521907 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | -0.00517728 |
| MTERF1 | mitochondrial transcription termination factor 1 | -0.00516949 |
| TRIM72 | tripartite motif containing 72, E3 ubiquitin protein ligase | -0.00516261 |
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) | -0.00516068 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) | -0.00515106 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.00510404 |
| ERI2 | ERI1 exoribonuclease family member 2 | -0.00508252 |
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | -0.00504562 |
| PLSCR2 | phospholipid scramblase 2 | -0.00502114 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.00501769 |
| LGMN | legumain | -0.00497 |
| RPL19 | ribosomal protein L19 | -0.00496044 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.00495617 |
| RPS13 | ribosomal protein S13 | -0.00486709 |
| IFRD1 | interferon-related developmental regulator 1 | -0.00484919 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.00483338 |
| MIPOL1 | mirror-image polydactyly 1 | -0.0048092 |
| RPL11 | ribosomal protein L11 | -0.0047901 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.00478134 |
| TRAM1 | translocation associated membrane protein 1 | -0.00470959 |
| DNASE1 | deoxyribonuclease I | -0.00468174 |
| MICU1 | mitochondrial calcium uptake 1 | -0.00466975 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.00465939 |
| GTDC1 | glycosyltransferase-like domain containing 1 | -0.00462003 |