| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idoxuridine perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Idoxuridine_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.145888 |
| EFNA5 | ephrin-A5 | 0.137537 |
| ASPH | aspartate beta-hydroxylase | 0.127662 |
| GDA | guanine deaminase | 0.0933297 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0789365 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0777487 |
| GRAMD1B | GRAM domain containing 1B | 0.0661164 |
| TXNRD1 | thioredoxin reductase 1 | 0.0653423 |
| NEK7 | NIMA-related kinase 7 | 0.0626383 |
| DST | dystonin | 0.0620707 |
| KYNU | kynureninase | 0.0593709 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.058287 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0579787 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0528814 |
| MYOF | myoferlin | 0.0497485 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0485409 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.048055 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.047493 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0461258 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0458284 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0439156 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0438203 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0413703 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0389032 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0385889 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0381466 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0379891 |
| MFF | mitochondrial fission factor | 0.0378445 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0376677 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0376288 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0367312 |
| PDE10A | phosphodiesterase 10A | 0.0367041 |
| RTN4 | reticulon 4 | 0.0363621 |
| AHNAK | AHNAK nucleoprotein | 0.0363034 |
| PCBP2 | poly(rC) binding protein 2 | 0.0362355 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0361267 |
| LDHA | lactate dehydrogenase A | 0.0360561 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0355874 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0355362 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0351086 |
| FLNB | filamin B, beta | 0.0347261 |
| NRCAM | neuronal cell adhesion molecule | 0.0344182 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0343051 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0340548 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0338697 |
| OGA | O-GlcNAcase | 0.0322236 |
| CTSC | cathepsin C | 0.032045 |
| PGK1 | phosphoglycerate kinase 1 | 0.0318456 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0317395 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.03136 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0313372 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0310352 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0309267 |
| TNPO1 | transportin 1 | 0.0300278 |
| ENAH | enabled homolog (Drosophila) | 0.0297802 |
| CANX | calnexin | 0.0294593 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0292707 |
| CD109 | CD109 molecule | 0.0290191 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0284195 |
| PCBP3 | poly(rC) binding protein 3 | 0.0283642 |
| RAB3B | RAB3B, member RAS oncogene family | 0.027718 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0274718 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0273934 |
| CARD16 | caspase recruitment domain family, member 16 | 0.027185 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0266591 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0265782 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0262447 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0258003 |
| RPL4 | ribosomal protein L4 | 0.0256399 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0252719 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0250635 |
| RBM39 | RNA binding motif protein 39 | 0.0249248 |
| CENPF | centromere protein F, 350/400kDa | 0.0248132 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0246919 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0243731 |
| TBXT | T-box transcription factor T | 0.0243333 |
| APP | amyloid beta (A4) precursor protein | 0.0242083 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0241514 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0240948 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0239434 |
| PTEN | phosphatase and tensin homolog | 0.0239315 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0238538 |
| COL4A6 | collagen, type IV, alpha 6 | 0.023708 |
| PHF20 | PHD finger protein 20 | 0.0234063 |
| MCL1 | myeloid cell leukemia 1 | 0.0234037 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.023233 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0231161 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0230763 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0229842 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0229711 |
| ATP13A3 | ATPase type 13A3 | 0.0225928 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0220738 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0220566 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0219236 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0210391 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | 0.0209933 |
| JMJD1C | jumonji domain containing 1C | 0.0208615 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0208467 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | 0.0207322 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0207193 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.101143 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0501958 |
| TMSB10 | thymosin beta 10 | -0.0486499 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0378427 |
| RPLP1 | ribosomal protein, large, P1 | -0.0369297 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0365267 |
| RPS6 | ribosomal protein S6 | -0.0346581 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0344147 |
| RPL35A | ribosomal protein L35a | -0.0308059 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0304661 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.026963 |
| CDH13 | cadherin 13 | -0.0251689 |
| FTL | ferritin, light polypeptide | -0.0230627 |
| VIM | vimentin | -0.0223732 |
| RPS19 | ribosomal protein S19 | -0.0222629 |
| LSAMP | limbic system-associated membrane protein | -0.0219566 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.021066 |
| RPL37A | ribosomal protein L37a | -0.0206305 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0202949 |
| EGR1 | early growth response 1 | -0.019229 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0175115 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0168704 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.016855 |
| RPS23 | ribosomal protein S23 | -0.0168208 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0165503 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.016528 |
| RPL31 | ribosomal protein L31 | -0.0165001 |
| RPL34 | ribosomal protein L34 | -0.0164907 |
| RPS27 | ribosomal protein S27 | -0.0163921 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0161571 |
| RPS29 | ribosomal protein S29 | -0.0158959 |
| MAP7 | microtubule-associated protein 7 | -0.0156599 |
| AUTS2 | autism susceptibility candidate 2 | -0.0152748 |
| LAMA5 | laminin, alpha 5 | -0.0152716 |
| SQSTM1 | sequestosome 1 | -0.0151942 |
| RPS8 | ribosomal protein S8 | -0.0151532 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0151057 |
| HLA-A | major histocompatibility complex, class I, A | -0.0148649 |
| RPS14 | ribosomal protein S14 | -0.0148453 |
| IL6 | interleukin 6 | -0.014502 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0144111 |
| HLA-B | major histocompatibility complex, class I, B | -0.0142709 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0142243 |
| RPS25 | ribosomal protein S25 | -0.0140358 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0140314 |
| PTMA | prothymosin, alpha | -0.013826 |
| RPL36A | ribosomal protein L36a | -0.0136838 |
| NCKAP5 | NCK-associated protein 5 | -0.0136616 |
| RPL36 | ribosomal protein L36 | -0.0133931 |
| NBEAL1 | neurobeachin-like 1 | -0.013391 |
| TENM2 | teneurin transmembrane protein 2 | -0.0132015 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0129272 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0126172 |
| RPL9 | ribosomal protein L9 | -0.0125146 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0123417 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0122805 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0121236 |
| RPL37 | ribosomal protein L37 | -0.0120662 |
| CTSL | cathepsin L | -0.0119143 |
| NDRG1 | N-myc downstream regulated 1 | -0.0118198 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0116227 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | -0.0115822 |
| RPS13 | ribosomal protein S13 | -0.011576 |
| IER3 | immediate early response 3 | -0.0115578 |
| AGR2 | anterior gradient 2 | -0.0114881 |
| RPL38 | ribosomal protein L38 | -0.0114479 |
| XYLT1 | xylosyltransferase I | -0.0114122 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0111675 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0110718 |
| RPLP2 | ribosomal protein, large, P2 | -0.0108919 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0107531 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0107413 |
| PKM | pyruvate kinase, muscle | -0.0103847 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -0.0095238 |
| NCOR2 | nuclear receptor corepressor 2 | -0.00951212 |
| CTBP2 | C-terminal binding protein 2 | -0.00942475 |
| RPS10 | ribosomal protein S10 | -0.00940795 |
| RPS17 | ribosomal protein S17 | -0.00938037 |
| ESM1 | endothelial cell-specific molecule 1 | -0.00936416 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00928096 |
| LMNA | lamin A/C | -0.00927603 |
| RPL28 | ribosomal protein L28 | -0.00924607 |
| RPS16 | ribosomal protein S16 | -0.00913411 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.00900248 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.00893629 |
| GNAS | GNAS complex locus | -0.00891077 |
| CA12 | carbonic anhydrase XII | -0.00886218 |
| RPS3 | ribosomal protein S3 | -0.00878495 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.00877922 |
| RPS24 | ribosomal protein S24 | -0.00870303 |
| RPS21 | ribosomal protein S21 | -0.00863877 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.00837075 |
| TENM3 | teneurin transmembrane protein 3 | -0.00828006 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.00821727 |
| RAD51B | RAD51 paralog B | -0.00814024 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.00808953 |
| C9ORF153 | chromosome 9 open reading frame 153 | -0.00801464 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.00797148 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.00783932 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.00778602 |