| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idoxuridine perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Idoxuridine_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.167335 |
| GPC6 | glypican 6 | 0.141341 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.13283 |
| NDRG1 | N-myc downstream regulated 1 | 0.114755 |
| FN1 | fibronectin 1 | 0.100697 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0991962 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0971935 |
| GLG1 | golgi glycoprotein 1 | 0.0918495 |
| VIM | vimentin | 0.0874266 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0859133 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0852179 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0812838 |
| DST | dystonin | 0.0745696 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0709036 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0677374 |
| RPL11 | ribosomal protein L11 | 0.0637708 |
| OSMR | oncostatin M receptor | 0.0612438 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0581241 |
| PKM | pyruvate kinase, muscle | 0.0564354 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0556477 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0546217 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0539442 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0526149 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0522174 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0507573 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0486601 |
| HMGA2 | high mobility group AT-hook 2 | 0.0486299 |
| RAD51B | RAD51 paralog B | 0.0461348 |
| BPTF | bromodomain PHD finger transcription factor | 0.045988 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0452986 |
| FNDC3B | fibronectin type III domain containing 3B | 0.04359 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0429956 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0427779 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0425692 |
| PDE10A | phosphodiesterase 10A | 0.0420049 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0408317 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0401571 |
| ITGA6 | integrin, alpha 6 | 0.0398608 |
| STC1 | stanniocalcin 1 | 0.0395959 |
| PTK2 | protein tyrosine kinase 2 | 0.0393892 |
| H3-3B | H3.3 histone B | 0.0392395 |
| ASPH | aspartate beta-hydroxylase | 0.0384386 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0371271 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.036007 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0359922 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.035588 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0355714 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0352566 |
| SEPTIN2 | septin 2 | 0.034935 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0347298 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0346857 |
| SPAG9 | sperm associated antigen 9 | 0.0342346 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0342002 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0340629 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0334292 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0333732 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.032698 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0324932 |
| JMJD1C | jumonji domain containing 1C | 0.0320443 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0320117 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0289775 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0278635 |
| GOLGA4 | golgin A4 | 0.0272384 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0271421 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0269625 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0260968 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0256549 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0244372 |
| RPL34 | ribosomal protein L34 | 0.0240423 |
| HDLBP | high density lipoprotein binding protein | 0.0239901 |
| OGA | O-GlcNAcase | 0.0229043 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0201316 |
| TJP1 | tight junction protein 1 | 0.0197869 |
| SRPK2 | SRSF protein kinase 2 | 0.0195859 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0188073 |
| RBM39 | RNA binding motif protein 39 | 0.0181368 |
| ZNF292 | zinc finger protein 292 | 0.0180461 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.017609 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0168188 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0166816 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0163057 |
| RPS16 | ribosomal protein S16 | 0.0162622 |
| GPHN | gephyrin | 0.0152412 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0149013 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0148667 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0147323 |
| MED13L | mediator complex subunit 13-like | 0.0147294 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0145607 |
| CD44 | CD44 molecule (Indian blood group) | 0.0143074 |
| PTMA | prothymosin, alpha | 0.0141869 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0137905 |
| RPL23 | ribosomal protein L23 | 0.013432 |
| PRELID2 | PRELI domain containing 2 | 0.0121354 |
| LAMB3 | laminin, beta 3 | 0.0117545 |
| PGK1 | phosphoglycerate kinase 1 | 0.0107896 |
| PCBP2 | poly(rC) binding protein 2 | 0.0106054 |
| NCOA3 | nuclear receptor coactivator 3 | 0.00970764 |
| SMYD3 | SET and MYND domain containing 3 | 0.00966108 |
| SQSTM1 | sequestosome 1 | 0.00918551 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.00902762 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | -0.109452 |
| RPS6 | ribosomal protein S6 | -0.0831004 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.080825 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.078774 |
| LMO7 | LIM domain 7 | -0.0756577 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0739287 |
| EGFR | epidermal growth factor receptor | -0.0716219 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.070001 |
| RPL7 | ribosomal protein L7 | -0.0670712 |
| LDHA | lactate dehydrogenase A | -0.0664252 |
| RPL37A | ribosomal protein L37a | -0.0660118 |
| RPS8 | ribosomal protein S8 | -0.0649924 |
| MYO1E | myosin IE | -0.0633675 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0630137 |
| NF1 | neurofibromin 1 | -0.0629767 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0623079 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0617533 |
| SBF2 | SET binding factor 2 | -0.0589073 |
| RPL31 | ribosomal protein L31 | -0.055915 |
| POTEF | POTE ankyrin domain family, member F | -0.0537887 |
| ACTG1 | actin gamma 1 | -0.0534151 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0524197 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0521711 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.050737 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0501532 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.048567 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0471277 |
| RPS3 | ribosomal protein S3 | -0.0448465 |
| FOXO3 | forkhead box O3 | -0.0440825 |
| RPS27A | ribosomal protein S27a | -0.0427929 |
| EFNA5 | ephrin-A5 | -0.0415768 |
| MYOF | myoferlin | -0.0405834 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0404235 |
| TMSB10 | thymosin beta 10 | -0.0400391 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0384591 |
| YBX3 | Y box binding protein 3 | -0.0383263 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0382329 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0373607 |
| TXNRD1 | thioredoxin reductase 1 | -0.0356716 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0353993 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0352924 |
| VMP1 | vacuole membrane protein 1 | -0.0350829 |
| CANX | calnexin | -0.0349369 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0341191 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0340465 |
| HDAC9 | histone deacetylase 9 | -0.0335658 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0329872 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0328575 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0325057 |
| TPM4 | tropomyosin 4 | -0.0324247 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0323213 |
| MYO6 | myosin VI | -0.0317084 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0302394 |
| FHIT | fragile histidine triad | -0.0299535 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0296643 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0293708 |
| RPL26 | ribosomal protein L26 | -0.0283922 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0270041 |
| RNF149 | ring finger protein 149 | -0.0267261 |
| PRKCA | protein kinase C, alpha | -0.026647 |
| SLTM | SAFB-like, transcription modulator | -0.0256945 |
| RPLP1 | ribosomal protein, large, P1 | -0.0249887 |
| FTL | ferritin, light polypeptide | -0.0248478 |
| ARRDC3 | arrestin domain containing 3 | -0.024772 |
| HDAC2 | histone deacetylase 2 | -0.0247099 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0245784 |
| RPS12 | ribosomal protein S12 | -0.0243608 |
| FMNL2 | formin-like 2 | -0.0242687 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0240107 |
| RPLP0 | ribosomal protein, large, P0 | -0.0234647 |
| VCL | vinculin | -0.02272 |
| MAP4 | microtubule-associated protein 4 | -0.0226065 |
| RORA | RAR-related orphan receptor A | -0.022565 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0222146 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0214755 |
| PDE8A | phosphodiesterase 8A | -0.0209095 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | -0.0205958 |
| RPL32 | ribosomal protein L32 | -0.0204054 |
| RPL12 | ribosomal protein L12 | -0.0204001 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0200953 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0200055 |
| ANXA2 | annexin A2 | -0.0197174 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0187357 |
| PHF3 | PHD finger protein 3 | -0.0180342 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0176584 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0172859 |
| B2M | beta-2-microglobulin | -0.016061 |
| GOLGB1 | golgin B1 | -0.0151817 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0147183 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0146406 |
| MT2A | metallothionein 2A | -0.0146399 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0144302 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0137019 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0136861 |
| EZR | ezrin | -0.012951 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0127215 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0121178 |
| RPS13 | ribosomal protein S13 | -0.0113288 |
| HELZ | helicase with zinc finger | -0.0109938 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0106173 |