| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idoxuridine perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Idoxuridine_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.103974 |
| MT2A | metallothionein 2A | 0.088156 |
| VIM | vimentin | 0.0830884 |
| AHNAK | AHNAK nucleoprotein | 0.0692693 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0649107 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0621102 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0550381 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0498025 |
| OGA | O-GlcNAcase | 0.0484485 |
| FN1 | fibronectin 1 | 0.0404089 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0402335 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0397413 |
| FMNL2 | formin-like 2 | 0.038568 |
| SMAD3 | SMAD family member 3 | 0.0384723 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0384209 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0379255 |
| MT1X | metallothionein 1X | 0.036795 |
| LDHA | lactate dehydrogenase A | 0.0364942 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0360881 |
| DST | dystonin | 0.0337806 |
| CALU | calumenin | 0.0319755 |
| ANO6 | anoctamin 6 | 0.031331 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0312445 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0304019 |
| FAT1 | FAT atypical cadherin 1 | 0.0302647 |
| IL6 | interleukin 6 | 0.0300345 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0298134 |
| SDC4 | syndecan 4 | 0.0297527 |
| ATP13A3 | ATPase type 13A3 | 0.0297211 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0292367 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0285554 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0283508 |
| RPS3 | ribosomal protein S3 | 0.0282959 |
| B2M | beta-2-microglobulin | 0.0277689 |
| UBC | ubiquitin C | 0.0277 |
| CTSB | cathepsin B | 0.0270277 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0266935 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0265842 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0265089 |
| PARD3 | par-3 family cell polarity regulator | 0.0263118 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0262218 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0261897 |
| RPL23 | ribosomal protein L23 | 0.0261793 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0260705 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0260024 |
| JAK1 | Janus kinase 1 | 0.0255378 |
| SEPTIN9 | septin 9 | 0.0253415 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0250859 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0250625 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0250255 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0248809 |
| CAVIN1 | caveolae associated protein 1 | 0.0248352 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0248223 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.024787 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0245908 |
| RPL36 | ribosomal protein L36 | 0.0245145 |
| ITGA6 | integrin, alpha 6 | 0.0245032 |
| STC1 | stanniocalcin 1 | 0.0240065 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0239327 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.023784 |
| EFNA5 | ephrin-A5 | 0.023637 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0236096 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | 0.0234746 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0233991 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0232725 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0231335 |
| ANKRD17 | ankyrin repeat domain 17 | 0.02306 |
| RPL11 | ribosomal protein L11 | 0.0225125 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0223628 |
| RPN2 | ribophorin II | 0.0217867 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0217382 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0214341 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0213755 |
| MSI2 | musashi RNA-binding protein 2 | 0.0212825 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0212667 |
| THRAP3 | thyroid hormone receptor associated protein 3 | 0.0211506 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | 0.0208657 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0208515 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0208189 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0206567 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0205065 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0204717 |
| RPS16 | ribosomal protein S16 | 0.0202638 |
| MSN | moesin | 0.0198807 |
| RPS5 | ribosomal protein S5 | 0.0198236 |
| SPAG9 | sperm associated antigen 9 | 0.0195831 |
| INHBA | inhibin, beta A | 0.0194799 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0193526 |
| ASPH | aspartate beta-hydroxylase | 0.0192954 |
| CD2AP | CD2-associated protein | 0.0192891 |
| APP | amyloid beta (A4) precursor protein | 0.019171 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0190294 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0190257 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | 0.0188495 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0187492 |
| RPL31 | ribosomal protein L31 | 0.0187473 |
| RPL3 | ribosomal protein L3 | 0.0187372 |
| EIF3M | eukaryotic translation initiation factor 3, subunit M | 0.0186362 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.0185213 |
| WAPL | WAPL cohesin release factor | 0.0185186 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.195838 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.133823 |
| NDRG1 | N-myc downstream regulated 1 | -0.0930811 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0715757 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0610551 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0506566 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0495711 |
| ZNF292 | zinc finger protein 292 | -0.0468388 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0467966 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0454203 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0439498 |
| FAM13A | family with sequence similarity 13, member A | -0.041862 |
| NRXN3 | neurexin 3 | -0.0417133 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.03886 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0386805 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0375137 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0361882 |
| LOX | lysyl oxidase | -0.0347094 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0333868 |
| FUS | FUS RNA binding protein | -0.0331183 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0330982 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0321828 |
| ZNF395 | zinc finger protein 395 | -0.0312834 |
| COL5A1 | collagen, type V, alpha 1 | -0.0311823 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0294152 |
| MORF4L1 | mortality factor 4 like 1 | -0.0288953 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0288822 |
| ANKRD37 | ankyrin repeat domain 37 | -0.0288756 |
| MEF2A | myocyte enhancer factor 2A | -0.0274025 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0272083 |
| RYBP | RING1 and YY1 binding protein | -0.0267036 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0266801 |
| RPL28 | ribosomal protein L28 | -0.0264828 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.026383 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0260232 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0257092 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0251728 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0249845 |
| VEGFA | vascular endothelial growth factor A | -0.0245591 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0245429 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0241285 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0240299 |
| TPI1 | triosephosphate isomerase 1 | -0.023831 |
| CDH13 | cadherin 13 | -0.0237442 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0235734 |
| CCDC14 | coiled-coil domain containing 14 | -0.0232838 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0232481 |
| TBCA | tubulin folding cofactor A | -0.0231164 |
| SEC61G | Sec61 gamma subunit | -0.0227679 |
| ALKBH5 | AlkB family member 5, RNA demethylase | -0.0225132 |
| VCAN | versican | -0.0224926 |
| PKM | pyruvate kinase, muscle | -0.0223058 |
| COL1A1 | collagen, type I, alpha 1 | -0.0222996 |
| SNX13 | sorting nexin 13 | -0.0219388 |
| TGDS | TDP-glucose 4,6-dehydratase | -0.0216331 |
| SEC24D | SEC24 family member D | -0.0214551 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0208051 |
| TMSB10 | thymosin beta 10 | -0.0205307 |
| LAMB1 | laminin, beta 1 | -0.0204566 |
| FLNA | filamin A, alpha | -0.0203337 |
| VCL | vinculin | -0.0201745 |
| CXXC5 | CXXC finger protein 5 | -0.0199776 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0198644 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0194657 |
| HM13 | histocompatibility (minor) 13 | -0.0194572 |
| ANLN | anillin, actin binding protein | -0.0192384 |
| SLTM | SAFB-like, transcription modulator | -0.0192243 |
| ATG7 | autophagy related 7 | -0.0191895 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0191664 |
| CMIP | c-Maf inducing protein | -0.0188902 |
| SKIC3 | SKI3 subunit of superkiller complex | -0.018887 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0188378 |
| MAP1B | microtubule-associated protein 1B | -0.018766 |
| GLG1 | golgi glycoprotein 1 | -0.0187038 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0186062 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0185169 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0184589 |
| PDCD10 | programmed cell death 10 | -0.0183944 |
| RPL36AL | ribosomal protein L36a-like | -0.0183161 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.018314 |
| HIP1 | huntingtin interacting protein 1 | -0.0181652 |
| SYNPO | synaptopodin | -0.0181644 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0180659 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0180599 |
| EIF3L | eukaryotic translation initiation factor 3, subunit L | -0.0179904 |
| UBN2 | ubinuclein 2 | -0.0178097 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0177805 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | -0.0176044 |
| XPO1 | exportin 1 | -0.0174954 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | -0.0174514 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0173749 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0173603 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.0173259 |
| ROS1 | ROS proto-oncogene 1 , receptor tyrosine kinase | -0.017305 |
| ACVR1 | activin A receptor, type I | -0.0169725 |
| AZIN1 | antizyme inhibitor 1 | -0.0169097 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0168874 |
| TAGLN2 | transgelin 2 | -0.0168397 |
| IFNGR2 | interferon gamma receptor 2 (interferon gamma transducer 1) | -0.0168297 |
| KLHL5 | kelch-like family member 5 | -0.0167449 |