Idoxuridine_SW 1271 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Idoxuridine perturbation in SW 1271 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Idoxuridine_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.165334
VIM vimentin 0.130024
AHNAK AHNAK nucleoprotein 0.0765141
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0756568
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0650624
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0599966
DSCAM Down syndrome cell adhesion molecule 0.0584943
LDHA lactate dehydrogenase A 0.0565061
SMYD3 SET and MYND domain containing 3 0.0544617
NAMPT nicotinamide phosphoribosyltransferase 0.0533421
PHLDB2 pleckstrin homology-like domain, family B, member 2 0.0521722
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0500305
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.049937
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0479173
CSNK1A1 casein kinase 1, alpha 1 0.0472483
ITCH itchy E3 ubiquitin protein ligase 0.0470112
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 0.0468355
BIRC3 baculoviral IAP repeat containing 3 0.0460815
SREK1 splicing regulatory glutamine/lysine-rich protein 1 0.0458589
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.0438578
ZFAND3 zinc finger, AN1-type domain 3 0.0433234
RPL4 ribosomal protein L4 0.0422234
RTN4 reticulon 4 0.0421552
PALM2AKAP2 PALM2 and AKAP2 fusion 0.0415716
COPB1 coatomer protein complex, subunit beta 1 0.0415008
ERC1 ELKS/RAB6-interacting/CAST family member 1 0.0407959
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 0.039212
TMSB10 thymosin beta 10 0.0379478
TXNRD1 thioredoxin reductase 1 0.0379294
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.037208
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0371164
CENPF centromere protein F, 350/400kDa 0.0369086
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.0367359
OSMR oncostatin M receptor 0.0348637
EEF2 eukaryotic translation elongation factor 2 0.0348621
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.0345317
TPX2 TPX2, microtubule-associated 0.0343631
MIS18BP1 MIS18 binding protein 1 0.0341973
DIAPH3 diaphanous-related formin 3 0.0339481
ANKRD28 ankyrin repeat domain 28 0.0328386
NBAS neuroblastoma amplified sequence 0.0324138
MAP3K20 mitogen-activated protein kinase kinase kinase 20 0.0314664
KIAA1328 KIAA1328 0.0311267
NCEH1 neutral cholesterol ester hydrolase 1 0.0309175
TRIP12 thyroid hormone receptor interactor 12 0.0308696
ZNF292 zinc finger protein 292 0.03085
MKI67 marker of proliferation Ki-67 0.0307538
PGK1 phosphoglycerate kinase 1 0.0305883
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0305804
WAC WW domain containing adaptor with coiled-coil 0.0305048
CKAP5 cytoskeleton associated protein 5 0.0304562
FMNL2 formin-like 2 0.0301039
PHF20 PHD finger protein 20 0.0300118
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.0291642
PPP6R3 protein phosphatase 6, regulatory subunit 3 0.0291093
ANLN anillin, actin binding protein 0.0290477
PRRC2B proline-rich coiled-coil 2B 0.0289499
SMC4 structural maintenance of chromosomes 4 0.0288086
PDE8A phosphodiesterase 8A 0.0285498
BZW1 basic leucine zipper and W2 domains 1 0.0284133
ZEB1 zinc finger E-box binding homeobox 1 0.0283357
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 0.028308
AKAP13 A kinase (PRKA) anchor protein 13 0.0281628
GSK3B glycogen synthase kinase 3 beta 0.0274777
FXR1 fragile X mental retardation, autosomal homolog 1 0.0274719
YAP1 Yes-associated protein 1 0.0273638
MNAT1 MNAT CDK-activating kinase assembly factor 1 0.0272538
SEC23A Sec23 homolog A (S. cerevisiae) 0.0271321
XPO1 exportin 1 0.0269956
NAP1L1 nucleosome assembly protein 1-like 1 0.0265219
BABAM2 BRISC and BRCA1 A complex member 2 0.0261412
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.0260512
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.026003
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 0.0255572
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.0248036
UBC ubiquitin C 0.0246885
PICALM phosphatidylinositol binding clathrin assembly protein 0.024657
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0246493
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.0246471
TUBA1B tubulin, alpha 1b 0.0245909
COG5 component of oligomeric golgi complex 5 0.0245625
SETD5 SET domain containing 5 0.0245452
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 0.0245228
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 0.0241938
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.0240152
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 0.0239139
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) 0.0238927
MYH9 myosin, heavy chain 9, non-muscle 0.0237974
SKP1 S-phase kinase-associated protein 1 0.0236976
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.0235807
PHF21A PHD finger protein 21A 0.0234235
ZMYND8 zinc finger, MYND-type containing 8 0.0233726
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 0.0233302
NUP58 nucleoporin 58 0.0233292
NFE2L2 nuclear factor, erythroid 2-like 2 0.0232937
MBNL1 muscleblind-like splicing regulator 1 0.0231796
VCL vinculin 0.0230482
KIF4A kinesin family member 4A 0.0230256
LOC112694756 uncharaterized LOC112694756 0.0229751
MYO9A myosin IXA 0.0229225

decreased expression

Symbol Name Standardized Value
HILPDA hypoxia inducible lipid droplet-associated -0.0553464
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 -0.0536943
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.0522181
EGR1 early growth response 1 -0.0468617
IGF2 insulin-like growth factor 2 -0.0417841
IER3 immediate early response 3 -0.0355163
NDRG1 N-myc downstream regulated 1 -0.0328857
N4BP2L2 NEDD4 binding protein 2-like 2 -0.0297878
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.028414
MACF1 microtubule-actin crosslinking factor 1 -0.0280266
ADM adrenomedullin -0.027598
FN1 fibronectin 1 -0.0272998
ESYT2 extended synaptotagmin-like protein 2 -0.0265822
GPC5 glypican 5 -0.0264944
RAB2A RAB2A, member RAS oncogene family -0.025547
PTPRK protein tyrosine phosphatase, receptor type, K -0.0251709
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.0234352
PTMA prothymosin, alpha -0.0218709
IGFBP3 insulin-like growth factor binding protein 3 -0.0218623
PODXL podocalyxin-like -0.0215792
VEGFA vascular endothelial growth factor A -0.0212587
PRKCA protein kinase C, alpha -0.0210716
ITGB4 integrin, beta 4 -0.0205629
CEMIP2 cell migration inducing hyaluronidase 2 -0.0201582
NALCN sodium leak channel, non selective -0.0200405
S100A10 S100 calcium binding protein A10 -0.0200182
PCED1B PC-esterase domain containing 1B -0.0195826
BHLHE40 basic helix-loop-helix family, member e40 -0.0190036
UBE2E2 ubiquitin-conjugating enzyme E2E 2 -0.0181004
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -0.0178216
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 -0.0177625
COL5A1 collagen, type V, alpha 1 -0.0176732
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -0.0175011
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -0.0174569
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0172993
PTBP3 polypyrimidine tract binding protein 3 -0.0171923
RAI14 retinoic acid induced 14 -0.017049
DDIT4 DNA-damage-inducible transcript 4 -0.0168857
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.0167774
TIMP2 TIMP metallopeptidase inhibitor 2 -0.0166699
MYOF myoferlin -0.0166113
FMN1 formin 1 -0.016386
OXSR1 oxidative stress responsive 1 -0.0163283
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36 -0.0162566
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 -0.0162227
MYO9B myosin IXB -0.0160367
UBE2Z ubiquitin-conjugating enzyme E2Z -0.0159739
CREB5 cAMP responsive element binding protein 5 -0.0158993
KIAA1671 KIAA1671 -0.0158502
CD2AP CD2-associated protein -0.0158363
TENT2 terminal nucleotidyltransferase 2 -0.0157536
RPS6 ribosomal protein S6 -0.0156523
LIN54 lin-54 DREAM MuvB core complex component -0.0156286
RPS27 ribosomal protein S27 -0.015606
TRAM2 translocation associated membrane protein 2 -0.0153834
SNX25 sorting nexin 25 -0.0153742
POTEF POTE ankyrin domain family, member F -0.0153529
EFNA5 ephrin-A5 -0.015282
UBE3A ubiquitin protein ligase E3A -0.0150753
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -0.0149134
SPATS2L spermatogenesis associated, serine-rich 2-like -0.014898
NOTCH2 notch 2 -0.0147069
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 -0.0146848
MKNK2 MAP kinase interacting serine/threonine kinase 2 -0.0146125
PDGFC platelet derived growth factor C -0.0145958
MARCHF4 membrane associated ring-CH-type finger 4 -0.014551
P3H2 prolyl 3-hydroxylase 2 -0.0144492
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0141935
KDM5B lysine (K)-specific demethylase 5B -0.014193
WARS1 tryptophanyl-tRNA synthetase 1 -0.0141432
EFL1 elongation factor like GTPase 1 -0.0141007
ECE1 endothelin converting enzyme 1 -0.0140459
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 -0.0140401
MYO10 myosin X -0.0140376
RALY RALY heterogeneous nuclear ribonucleoprotein -0.0140278
CLEC2D C-type lectin domain family 2, member D -0.0139665
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase -0.0138854
RBMS1 RNA binding motif, single stranded interacting protein 1 -0.0138175
KLHL42 kelch-like family member 42 -0.0137791
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D -0.0137688
NPAS2 neuronal PAS domain protein 2 -0.0137267
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 -0.0136765
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -0.0136725
ANGPTL4 angiopoietin-like 4 -0.0135213
ZCCHC7 zinc finger, CCHC domain containing 7 -0.013513
CLPTM1 cleft lip and palate associated transmembrane protein 1 -0.013483
HMGA2 high mobility group AT-hook 2 -0.0133765
CMIP c-Maf inducing protein -0.0133669
RPL35A ribosomal protein L35a -0.0133044
MLLT6 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 -0.0132717
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 -0.0132708
PRMT2 protein arginine methyltransferase 2 -0.0132697
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae) -0.0132492
SF3B2 splicing factor 3b, subunit 2, 145kDa -0.0132182
AFDN afadin, adherens junction formation factor -0.0132119
SNED1 sushi, nidogen and EGF-like domains 1 -0.0131915
GOLPH3 golgi phosphoprotein 3 (coat-protein) -0.0131884
PTPRG protein tyrosine phosphatase, receptor type, G -0.0131569
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 -0.0131351
SHB Src homology 2 domain containing adaptor protein B -0.0130499