Ileitis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description An inflammatory bowel disease characterized by inflammation located_in ileum, has_symptom diarrhea, has_symptom abdominal pain, often in the right lower quadrant, has_symptom weight loss. (Human Disease Ontology, DOID_0060189)
Similar Terms
Downloads & Tools

Genes

373 genes co-occuring with the disease Ileitis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
TMEM201 transmembrane protein 201 3.618
NOD2 nucleotide-binding oligomerization domain containing 2 2.828
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 2.676
TNF tumor necrosis factor 2.655
IL10 interleukin 10 2.54
IFNG interferon, gamma 2.482
CD4 CD4 molecule 2.44
IL22 interleukin 22 2.424
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 2.416
IRGM immunity-related GTPase family, M 2.405
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 2.382
IL17A interleukin 17A 2.364
IL1B interleukin 1, beta 2.325
CCL25 chemokine (C-C motif) ligand 25 2.322
CCR9 chemokine (C-C motif) receptor 9 2.319
XBP1 X-box binding protein 1 2.275
ACKR2 atypical chemokine receptor 2 2.273
IL6 interleukin 6 2.262
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 2.262
FOXP3 forkhead box P3 2.213
CRP C-reactive protein, pentraxin-related 2.188
TLR4 toll-like receptor 4 2.151
REG3G regenerating islet-derived 3 gamma 2.141
CD8A CD8a molecule 2.097
DEFA5 defensin, alpha 5, Paneth cell-specific 2.09
IL18 interleukin 18 2.07
MYD88 myeloid differentiation primary response 88 2.067
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2 2.062
IL13 interleukin 13 2.06
OCLN occludin 2.054
IL23R interleukin 23 receptor 2.046
IL4 interleukin 4 2.04
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 2.028
CLDN2 claudin 2 2.019
TGFB1 transforming growth factor, beta 1 2.011
DEFA6 defensin, alpha 6, Paneth cell-specific 2.003
MUC2 mucin 2, oligomeric mucus/gel-forming 1.994
IL23A interleukin 23, alpha subunit p19 1.986
IL5 interleukin 5 1.976
RAG2 recombination activating gene 2 1.966
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 1.956
RIPK3 receptor-interacting serine-threonine kinase 3 1.955
TLR5 toll-like receptor 5 1.952
TBX21 T-box 21 1.941
IL33 interleukin 33 1.923
MPO myeloperoxidase 1.922
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 1.918
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.905
RAG1 recombination activating gene 1 1.885
ALB albumin 1.882
TLR2 toll-like receptor 2 1.881
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.87
SELL selectin L 1.863
ERN2 endoplasmic reticulum to nucleus signaling 2 1.86
NOD1 nucleotide-binding oligomerization domain containing 1 1.859
FADD Fas (TNFRSF6)-associated via death domain 1.858
IL2 interleukin 2 1.856
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.825
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 1.817
IL1A interleukin 1, alpha 1.812
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.809
IL10RA interleukin 10 receptor, alpha 1.803
ERN1 endoplasmic reticulum to nucleus signaling 1 1.802
PTPRC protein tyrosine phosphatase, receptor type, C 1.788
CXCL8 chemokine (C-X-C motif) ligand 8 1.772
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.748
TJP1 tight junction protein 1 1.745
MLKL mixed lineage kinase domain-like 1.718
CCRL2 chemokine (C-C motif) receptor-like 2 1.71
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 1.71
TLR9 toll-like receptor 9 1.706
CCR6 chemokine (C-C motif) receptor 6 1.705
CLDN7 claudin 7 1.694
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.691
NR1H4 nuclear receptor subfamily 1, group H, member 4 1.69
CARD9 caspase recruitment domain family, member 9 1.685
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.683
CCL2 chemokine (C-C motif) ligand 2 1.675
NLRP6 NLR family, pyrin domain containing 6 1.669
CCR7 chemokine (C-C motif) receptor 7 1.668
CLDN1 claudin 1 1.657
ZBP1 Z-DNA binding protein 1 1.651
RIPK2 receptor-interacting serine-threonine kinase 2 1.647
CCR2 chemokine (C-C motif) receptor 2 1.613
ATOH1 atonal homolog 1 (Drosophila) 1.601
IL17F interleukin 17F 1.6
ITGB7 integrin, beta 7 1.596
AGR2 anterior gradient 2 1.594
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.583
REG3A regenerating islet-derived 3 alpha 1.582
TAC1 tachykinin, precursor 1 1.577
SELPLG selectin P ligand 1.567
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.564
LTF lactotransferrin 1.56
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 1.551
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 1.547
CCL20 chemokine (C-C motif) ligand 20 1.546
GATA3 GATA binding protein 3 1.546
FGF19 fibroblast growth factor 19 1.545
CXCL10 chemokine (C-X-C motif) ligand 10 1.544
CD300C CD300c molecule 1.533
VCAM1 vascular cell adhesion molecule 1 1.532
ACTB actin, beta 1.532
IL15 interleukin 15 1.526
GPBAR1 G protein-coupled bile acid receptor 1 1.525
FABP6 fatty acid binding protein 6, ileal 1.522
CLEC7A C-type lectin domain family 7, member A 1.511
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 1.509
STAT1 signal transducer and activator of transcription 1, 91kDa 1.503
NLRP3 NLR family, pyrin domain containing 3 1.497
DLG5 discs, large homolog 5 (Drosophila) 1.495
CLDN3 claudin 3 1.494
FFAR2 free fatty acid receptor 2 1.489
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.486
AOC3 amine oxidase, copper containing 3 1.486
CX3CR1 chemokine (C-X3-C motif) receptor 1 1.481
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 1.478
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.476
CD40 CD40 molecule, TNF receptor superfamily member 5 1.473
ICAM1 intercellular adhesion molecule 1 1.47
AHR aryl hydrocarbon receptor 1.469
CCL5 chemokine (C-C motif) ligand 5 1.466
CD44 CD44 molecule (Indian blood group) 1.462
TFF3 trefoil factor 3 (intestinal) 1.46
CXCR3 chemokine (C-X-C motif) receptor 3 1.457
FUT2 fucosyltransferase 2 (secretor status included) 1.45
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.445
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.434
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1.423
SLC51A solute carrier family 51, alpha subunit 1.422
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.42
IL9 interleukin 9 1.419
YIPF6 Yip1 domain family, member 6 1.417
PPARG peroxisome proliferator-activated receptor gamma 1.412
IL1R1 interleukin 1 receptor, type I 1.41
CD69 CD69 molecule 1.409
CCL3 chemokine (C-C motif) ligand 3 1.404
LRRK2 leucine-rich repeat kinase 2 1.401
TLR3 toll-like receptor 3 1.401
CD40LG CD40 ligand 1.397
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 1.395
ICOS inducible T-cell co-stimulator 1.394
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.393
DUOX2 dual oxidase 2 1.389
MRGPRE MAS-related GPR, member E 1.389
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 1.388
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.388
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.386
LCN2 lipocalin 2 1.382
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 1.382
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.381
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.381
RORC RAR-related orphan receptor C 1.378
IL10RB interleukin 10 receptor, beta 1.378
TSLP thymic stromal lymphopoietin 1.375
PTPN2 protein tyrosine phosphatase, non-receptor type 2 1.375
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.374
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.369
IL17RA interleukin 17 receptor A 1.369
IFNB1 interferon, beta 1, fibroblast 1.368
CCL11 chemokine (C-C motif) ligand 11 1.366
TRADD TNFRSF1A-associated via death domain 1.364
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1 1.364
ATG5 autophagy related 5 1.364
PFN4 profilin family, member 4 1.361
SLC26A3 solute carrier family 26 (anion exchanger), member 3 1.361
CCL21 chemokine (C-C motif) ligand 21 1.358
PFN3 profilin 3 1.356
CD19 CD19 molecule 1.354
RETNLB resistin like beta 1.353
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 1.353
CD28 CD28 molecule 1.353
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.345
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.344
CCL4 chemokine (C-C motif) ligand 4 1.342
NCR1 natural cytotoxicity triggering receptor 1 1.333
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 1.332
GSDMD gasdermin D 1.33
MAP3K12 mitogen-activated protein kinase kinase kinase 12 1.328
TTC7A tetratricopeptide repeat domain 7A 1.328
ATG7 autophagy related 7 1.327
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 1.326
HP haptoglobin 1.325
IL7 interleukin 7 1.319
HPRT1 hypoxanthine phosphoribosyltransferase 1 1.315
JAK2 Janus kinase 2 1.312
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.311
CD86 CD86 molecule 1.307
CD80 CD80 molecule 1.307
ATF6 activating transcription factor 6 1.304
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.304
VIP vasoactive intestinal peptide 1.304
SLC51B solute carrier family 51, beta subunit 1.304
NLRP1 NLR family, pyrin domain containing 1 1.303
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.302
TPMT thiopurine S-methyltransferase 1.299
IL7R interleukin 7 receptor 1.297
IL33R interleukin 33 receptor 1.297
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 1.296
IL26 interleukin 26 1.294
CXCL9 chemokine (C-X-C motif) ligand 9 1.293
SELE selectin E 1.287
NLRC4 NLR family, CARD domain containing 4 1.287
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 1.285
MAP3K13 mitogen-activated protein kinase kinase kinase 13 1.281
TLR1 toll-like receptor 1 1.28
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.274
TRPV1 transient receptor potential cation channel, subfamily V, member 1 1.272
SEL1L sel-1 suppressor of lin-12-like (C. elegans) 1.271
PXDNL peroxidasin-like 1.27
PXDN peroxidasin 1.268
CXCL2 chemokine (C-X-C motif) ligand 2 1.267
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.262
BHLHA15 basic helix-loop-helix family, member a15 1.259
BATF3 basic leucine zipper transcription factor, ATF-like 3 1.259
CCL19 chemokine (C-C motif) ligand 19 1.257
JUN jun proto-oncogene 1.255
FABP2 fatty acid binding protein 2, intestinal 1.254
IL11 interleukin 11 1.254
CCR3 chemokine (C-C motif) receptor 3 1.252
MRGPRF MAS-related GPR, member F 1.251
CLDN8 claudin 8 1.25
CFLAR CASP8 and FADD-like apoptosis regulator 1.248
GCG glucagon 1.248
IL12RB1 interleukin 12 receptor, beta 1 1.245
CSF3 colony stimulating factor 3 (granulocyte) 1.238
SMAD7 SMAD family member 7 1.235
CHUK conserved helix-loop-helix ubiquitous kinase 1.234
FOS FBJ murine osteosarcoma viral oncogene homolog 1.233
DUOXA2 dual oxidase maturation factor 2 1.232
IL2RA interleukin 2 receptor, alpha 1.229
MMP9 matrix metallopeptidase 9 1.227
IFNA1 interferon, alpha 1 1.223
SUCNR1 succinate receptor 1 1.223
CD68 CD68 molecule 1.223
RSPO1 R-spondin 1 1.222
REL v-rel avian reticuloendotheliosis viral oncogene homolog 1.221
LTA lymphotoxin alpha 1.22
ITLN1 intelectin 1 (galactofuranose binding) 1.218
CCR1 chemokine (C-C motif) receptor 1 1.217
WNT3 wingless-type MMTV integration site family, member 3 1.214
IL18R1 interleukin 18 receptor 1 1.213
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 1.209
HCAR2 hydroxycarboxylic acid receptor 2 1.207
DEFB4A defensin, beta 4A 1.204
SLC26A6 solute carrier family 26 (anion exchanger), member 6 1.202
IDO1 indoleamine 2,3-dioxygenase 1 1.197
FASLG Fas ligand (TNF superfamily, member 6) 1.195
AIM2 absent in melanoma 2 1.189
NOX1 NADPH oxidase 1 1.189
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 1.184
IL1RN interleukin 1 receptor antagonist 1.183
PIGR polymeric immunoglobulin receptor 1.182
PFN1 profilin 1 1.18
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 1.18
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 1.176
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 1.173
TLR7 toll-like receptor 7 1.173
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.171
GPX2 glutathione peroxidase 2 1.171
SETDB1 SET domain, bifurcated 1 1.171
CLDN15 claudin 15 1.168
MEFV Mediterranean fever 1.164
CLDN4 claudin 4 1.163
DEFB1 defensin, beta 1 1.159
CXCL11 chemokine (C-X-C motif) ligand 11 1.151
S1PR2 sphingosine-1-phosphate receptor 2 1.15
TJP2 tight junction protein 2 1.15
DEFA1B defensin, alpha 1B 1.144
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 1.144
NOS2 nitric oxide synthase 2, inducible 1.142
MUC19 mucin 19, oligomeric 1.14
CSF1 colony stimulating factor 1 (macrophage) 1.139
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 1.135
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 1.133
MMP7 matrix metallopeptidase 7 1.13
NTAN1 N-terminal asparagine amidase 1.127
CYLD cylindromatosis (turban tumor syndrome) 1.127
F11R F11 receptor 1.126
CD1D CD1d molecule 1.125
TREM1 triggering receptor expressed on myeloid cells 1 1.123
S1PR5 sphingosine-1-phosphate receptor 5 1.122
NELFCD negative elongation factor complex member C/D 1.119
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1 1.118
TYK2 tyrosine kinase 2 1.116
RETN resistin 1.116
ALPI alkaline phosphatase, intestinal 1.108
TLR6 toll-like receptor 6 1.103
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 1.099
DEFB103A defensin, beta 103A 1.099
MAPK3 mitogen-activated protein kinase 3 1.097
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 1.096
NT5E 5'-nucleotidase, ecto (CD73) 1.095
G0S2 G0/G1 switch 2 1.092
FLT3LG fms-related tyrosine kinase 3 ligand 1.091
EGF epidermal growth factor 1.091
ACE2 angiotensin I converting enzyme 2 1.086
CGNL1 cingulin-like 1 1.086
CYBB cytochrome b-245, beta polypeptide 1.084
OLFM4 olfactomedin 4 1.081
IL22RA1 interleukin 22 receptor, alpha 1 1.081
STAT4 signal transducer and activator of transcription 4 1.08
DCLK1 doublecortin-like kinase 1 1.079
KLRB1 killer cell lectin-like receptor subfamily B, member 1 1.079
OSM oncostatin M 1.078
AREG amphiregulin 1.077
SPI1 Spi-1 proto-oncogene 1.074
IL27RA interleukin 27 receptor, alpha 1.074
IL22RA2 interleukin 22 receptor, alpha 2 1.072
NKX2-3 NK2 homeobox 3 1.072
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.071
OTULIN OTU deubiquitinase with linear linkage specificity 1.07
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 1.069
VIL1 villin 1 1.067
KLRG1 killer cell lectin-like receptor subfamily G, member 1 1.066
ADNP activity-dependent neuroprotector homeobox 1.065
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain 1.062
CD274 CD274 molecule 1.061
JAK1 Janus kinase 1 1.06
ELANE elastase, neutrophil expressed 1.059
ITLN2 intelectin 2 1.059
VIPR1 vasoactive intestinal peptide receptor 1 1.058
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 1.054
JAK3 Janus kinase 3 1.053
STAT5A signal transducer and activator of transcription 5A 1.052
IL2RB interleukin 2 receptor, beta 1.052
INS insulin 1.05
TFF2 trefoil factor 2 1.05
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 1.048
LEP leptin 1.048
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.044
IL3 interleukin 3 1.043
LTB lymphotoxin beta (TNF superfamily, member 3) 1.042
PYCARD PYD and CARD domain containing 1.039
IRF3 interferon regulatory factor 3 1.039
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 1.038
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.037
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 1.036
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 1.036
CAMP cathelicidin antimicrobial peptide 1.036
NPY neuropeptide Y 1.035
BCL2 B-cell CLL/lymphoma 2 1.035
NOG noggin 1.033
IL12RB2 interleukin 12 receptor, beta 2 1.032
MUC1 mucin 1, cell surface associated 1.03
PPARA peroxisome proliferator-activated receptor alpha 1.028
TP53 tumor protein p53 1.028
IRAK1 interleukin-1 receptor-associated kinase 1 1.027
CXCL3 chemokine (C-X-C motif) ligand 3 1.026
STAT5B signal transducer and activator of transcription 5B 1.023
DPY19L3 dpy-19-like 3 (C. elegans) 1.023
MMP3 matrix metallopeptidase 3 1.021
IL34 interleukin 34 1.02
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 1.017
CXCL16 chemokine (C-X-C motif) ligand 16 1.016
DEFA1 defensin, alpha 1 1.014
SMAD3 SMAD family member 3 1.014
HLA-B major histocompatibility complex, class I, B 1.014
FFAR3 free fatty acid receptor 3 1.013
MUC4 mucin 4, cell surface associated 1.012
ECM1 extracellular matrix protein 1 1.012
LY96 lymphocyte antigen 96 1.012
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.011
IL18RAP interleukin 18 receptor accessory protein 1.01
CXCL13 chemokine (C-X-C motif) ligand 13 1.009
SLC6A19 solute carrier family 6 (neutral amino acid transporter), member 19 1.007
CCL24 chemokine (C-C motif) ligand 24 1.003
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 1.003
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.003
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.002
CHAT choline O-acetyltransferase 1.002
ADA adenosine deaminase 1.001
TRPV6 transient receptor potential cation channel, subfamily V, member 6 1.0