Imipramine Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom. (Chemical Entities of Biological Interest Ontology, CHEBI_47499)
External Link http://ctdbase.org/detail.go?type=chem&acc=D007099
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Genes

38 genes/proteins interacting with the chemical Imipramine from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ACHE acetylcholinesterase (Yt blood group)
ADRB1 adrenoceptor beta 1
ADRB2 adrenoceptor beta 2, surface
ALB albumin
BDNF brain-derived neurotrophic factor
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CAT catalase
CREB1 cAMP responsive element binding protein 1
CRH corticotropin releasing hormone
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A cytochrome P450, family 3, subfamily A
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5
GSTP1 glutathione S-transferase pi 1
HMBS hydroxymethylbilane synthase
HSPA8 heat shock 70kDa protein 8
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
ORM2 orosomucoid 2
PARP1 poly (ADP-ribose) polymerase 1
PLCG1 phospholipase C, gamma 1
POMC proopiomelanocortin
SLC22A2 solute carrier family 22 (organic cation transporter), member 2
SLC22A3 solute carrier family 22 (organic cation transporter), member 3
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SREBF1 sterol regulatory element binding transcription factor 1
SREBF2 sterol regulatory element binding transcription factor 2
TAC1 tachykinin, precursor 1
TNF tumor necrosis factor
UGT1A4 UDP glucuronosyltransferase 1 family, polypeptide A4