| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (hydrochloride) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Imiquimod (hydrochloride)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.269042 |
| LOX | lysyl oxidase | 0.162471 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.161539 |
| AHNAK | AHNAK nucleoprotein | 0.129568 |
| LOXL2 | lysyl oxidase-like 2 | 0.127325 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.097011 |
| THBS2 | thrombospondin 2 | 0.08916 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0870658 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0827327 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0810064 |
| VIM | vimentin | 0.0739356 |
| UBC | ubiquitin C | 0.0736096 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0715151 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.067134 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0658407 |
| FBN1 | fibrillin 1 | 0.0655681 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0649333 |
| SEPTIN9 | septin 9 | 0.0628254 |
| COL5A1 | collagen, type V, alpha 1 | 0.059978 |
| FLNA | filamin A, alpha | 0.0558514 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0553306 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0524193 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0449868 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0439833 |
| PODXL | podocalyxin-like | 0.0432602 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0425518 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0422257 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.041508 |
| CDH13 | cadherin 13 | 0.0403672 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.0402488 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0401748 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0392157 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0365705 |
| HDLBP | high density lipoprotein binding protein | 0.0364825 |
| C1D | C1D nuclear receptor corepressor | 0.035915 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0358997 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0355795 |
| HLA-A | major histocompatibility complex, class I, A | 0.0353459 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0352912 |
| APP | amyloid beta (A4) precursor protein | 0.0348883 |
| BSG | basigin (Ok blood group) | 0.0346181 |
| GOLGA2 | golgin A2 | 0.0335693 |
| L1CAM | L1 cell adhesion molecule | 0.0328687 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0324489 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0323595 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0319243 |
| PRSS23 | protease, serine, 23 | 0.0318206 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0315825 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0313899 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0311846 |
| MSI2 | musashi RNA-binding protein 2 | 0.0299231 |
| HLA-E | major histocompatibility complex, class I, E | 0.0298172 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0295559 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0295138 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0294418 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.0293367 |
| AUTS2 | autism susceptibility candidate 2 | 0.0289696 |
| INSIG1 | insulin induced gene 1 | 0.0289035 |
| TMSB10 | thymosin beta 10 | 0.0288688 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0284257 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.028373 |
| DHFR | dihydrofolate reductase | 0.0281702 |
| CD109 | CD109 molecule | 0.0281374 |
| ARRDC3 | arrestin domain containing 3 | 0.0280691 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0277009 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0276299 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0275158 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0274247 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0271986 |
| CALU | calumenin | 0.0271862 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0270696 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0267911 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | 0.0264568 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0256322 |
| RAB18 | RAB18, member RAS oncogene family | 0.0254409 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0253691 |
| RPL3 | ribosomal protein L3 | 0.0252755 |
| COPA | coatomer protein complex, subunit alpha | 0.0250908 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.024752 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0243153 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | 0.0237235 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0236969 |
| RASAL2 | RAS protein activator like 2 | 0.0235353 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0231596 |
| MCL1 | myeloid cell leukemia 1 | 0.0226718 |
| PKM | pyruvate kinase, muscle | 0.0225172 |
| FAM114A1 | family with sequence similarity 114, member A1 | 0.0223178 |
| FN1 | fibronectin 1 | 0.0221004 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0216886 |
| AFDN | afadin, adherens junction formation factor | 0.0215561 |
| FRMD5 | FERM domain containing 5 | 0.0214558 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 0.0212127 |
| NCKAP1 | NCK-associated protein 1 | 0.0210859 |
| TPM4 | tropomyosin 4 | 0.0208571 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0208509 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0205754 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0205182 |
| ANXA6 | annexin A6 | 0.0205048 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.0200009 |
| LDHA | lactate dehydrogenase A | 0.0199865 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.155735 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.139171 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.137505 |
| MT2A | metallothionein 2A | -0.121719 |
| CD44 | CD44 molecule (Indian blood group) | -0.0807229 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0780688 |
| PLAT | plasminogen activator, tissue | -0.0530468 |
| S100A10 | S100 calcium binding protein A10 | -0.049663 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0424764 |
| SEPTIN7 | septin 7 | -0.0416218 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0413256 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0376256 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0374423 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0363909 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0363464 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0362973 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0352026 |
| COL1A2 | collagen, type I, alpha 2 | -0.0347492 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0340326 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0338015 |
| CENPF | centromere protein F, 350/400kDa | -0.033635 |
| RPS6 | ribosomal protein S6 | -0.0332206 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0328932 |
| ASPH | aspartate beta-hydroxylase | -0.0327532 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0326842 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0314326 |
| RPS2 | ribosomal protein S2 | -0.0310207 |
| RPS8 | ribosomal protein S8 | -0.0305986 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0305852 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0304171 |
| RPS19 | ribosomal protein S19 | -0.0296284 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | -0.0295301 |
| MX2 | MX dynamin-like GTPase 2 | -0.0289564 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0288427 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0286303 |
| CLTC | clathrin, heavy chain (Hc) | -0.0283177 |
| RBM25 | RNA binding motif protein 25 | -0.0282563 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0275455 |
| RPL28 | ribosomal protein L28 | -0.0275075 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0273718 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0270827 |
| RUNX1 | runt-related transcription factor 1 | -0.0269063 |
| RPL36 | ribosomal protein L36 | -0.0268364 |
| RPL26 | ribosomal protein L26 | -0.026684 |
| RPS24 | ribosomal protein S24 | -0.0260738 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0251929 |
| RPL35A | ribosomal protein L35a | -0.025146 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0250971 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0250551 |
| PMP22 | peripheral myelin protein 22 | -0.0250534 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0246867 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0246364 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0246056 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0241627 |
| RASA2 | RAS p21 protein activator 2 | -0.0238204 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0237554 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0236455 |
| SBF2 | SET binding factor 2 | -0.0235978 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0235787 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0233976 |
| SVIL | supervillin | -0.0233827 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0231931 |
| RIGI | RNA sensor RIG-I | -0.0229529 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0229083 |
| RPL34 | ribosomal protein L34 | -0.0227523 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0227355 |
| TRIM56 | tripartite motif containing 56 | -0.0227271 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0225015 |
| IL6ST | interleukin 6 signal transducer | -0.0224831 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0224506 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0224153 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0222891 |
| MPZL1 | myelin protein zero-like 1 | -0.0222334 |
| IFI44 | interferon-induced protein 44 | -0.0221952 |
| RPLP1 | ribosomal protein, large, P1 | -0.0221586 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.022119 |
| RPL12 | ribosomal protein L12 | -0.0219072 |
| SPAG9 | sperm associated antigen 9 | -0.0218053 |
| TDRD7 | tudor domain containing 7 | -0.0213253 |
| CLU | clusterin | -0.0211474 |
| RPL19 | ribosomal protein L19 | -0.0210047 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0208609 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0207963 |
| PRKCE | protein kinase C, epsilon | -0.020731 |
| SP3 | Sp3 transcription factor | -0.0206744 |
| JMJD1C | jumonji domain containing 1C | -0.020518 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0204814 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0204274 |
| PRKD3 | protein kinase D3 | -0.0202475 |
| RAD51B | RAD51 paralog B | -0.0201831 |
| ADAR | adenosine deaminase, RNA-specific | -0.020117 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0196791 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0196788 |
| PLSCR1 | phospholipid scramblase 1 | -0.0195022 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0194833 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.0194618 |
| TENM3 | teneurin transmembrane protein 3 | -0.0188692 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0187375 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0185678 |
| ZNF638 | zinc finger protein 638 | -0.0185534 |
