| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (hydrochloride) perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Imiquimod (hydrochloride)_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | 0.0812091 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0591437 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0584037 |
| KIF5B | kinesin family member 5B | 0.0499881 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0440576 |
| RPL3 | ribosomal protein L3 | 0.0392709 |
| TMEM41B | transmembrane protein 41B | 0.0372349 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0311847 |
| CLDND1 | claudin domain containing 1 | 0.0289351 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0267265 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0260505 |
| NCKAP1 | NCK-associated protein 1 | 0.0252597 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0246294 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0245994 |
| CCNL1 | cyclin L1 | 0.0241563 |
| RACK1 | receptor for activated C kinase 1 | 0.0239996 |
| RPL4 | ribosomal protein L4 | 0.0234925 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0229886 |
| MKI67 | marker of proliferation Ki-67 | 0.0228764 |
| XPO1 | exportin 1 | 0.0224741 |
| NEK7 | NIMA-related kinase 7 | 0.0219253 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0202564 |
| TPI1 | triosephosphate isomerase 1 | 0.0199673 |
| DHFR | dihydrofolate reductase | 0.0197728 |
| SDHA | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 0.0196039 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0193024 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0187187 |
| PRKCI | protein kinase C, iota | 0.0184086 |
| H1-0 | H1.0 linker histone | 0.0177771 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.0177215 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.017553 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0173075 |
| CCT7 | chaperonin containing TCP1, subunit 7 (eta) | 0.0171252 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0170067 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0165494 |
| HLA-A | major histocompatibility complex, class I, A | 0.0165459 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0161568 |
| PNN | pinin, desmosome associated protein | 0.0161205 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.01602 |
| THOC1 | THO complex 1 | 0.0159855 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0158238 |
| HLTF | helicase-like transcription factor | 0.0152716 |
| AXIN2 | axin 2 | 0.0152403 |
| TCP1 | t-complex 1 | 0.0149138 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0148758 |
| ETNK1 | ethanolamine kinase 1 | 0.0148383 |
| ARRDC3 | arrestin domain containing 3 | 0.0147974 |
| CEP192 | centrosomal protein 192kDa | 0.0146723 |
| ECT2 | epithelial cell transforming 2 | 0.0146178 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.014606 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.0145558 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0143519 |
| TNPO1 | transportin 1 | 0.0142548 |
| CPOX | coproporphyrinogen oxidase | 0.0141807 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0140476 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0139657 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0137907 |
| PATL1 | protein associated with topoisomerase II homolog 1 (yeast) | 0.0136077 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0135732 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.0135615 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0135591 |
| HMGA1 | high mobility group AT-hook 1 | 0.013536 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | 0.013429 |
| GASK1B | golgi associated kinase 1B | 0.0134195 |
| HELB | helicase (DNA) B | 0.013403 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0133895 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.01303 |
| OXR1 | oxidation resistance 1 | 0.0128307 |
| CCN2 | cellular communication network factor 2 | 0.0127468 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0126922 |
| TGIF1 | TGFB-induced factor homeobox 1 | 0.0126318 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0126255 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0126145 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0123119 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0122052 |
| SFTPA2 | surfactant protein A2 | 0.0121234 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0120745 |
| XPC | xeroderma pigmentosum, complementation group C | 0.0120664 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0119097 |
| ATP11A | ATPase, class VI, type 11A | 0.0119044 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0118529 |
| KLC1 | kinesin light chain 1 | 0.0117022 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0116443 |
| CDYL | chromodomain protein, Y-like | 0.0115753 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | 0.0115305 |
| CPNE1 | copine I | 0.0115204 |
| TM7SF3 | transmembrane 7 superfamily member 3 | 0.011491 |
| PLK2 | polo-like kinase 2 | 0.0114741 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0114665 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0113459 |
| CLTC | clathrin, heavy chain (Hc) | 0.0112369 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0110984 |
| BSG | basigin (Ok blood group) | 0.0110924 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | 0.0110701 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0110609 |
| SSRP1 | structure specific recognition protein 1 | 0.0110154 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0109657 |
| FLNA | filamin A, alpha | 0.0109291 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0109071 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0108853 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.197135 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.185477 |
| NLGN1 | neuroligin 1 | -0.130915 |
| TMSB10 | thymosin beta 10 | -0.124511 |
| HMGA2 | high mobility group AT-hook 2 | -0.0841101 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.077595 |
| PCDH7 | protocadherin 7 | -0.0671791 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0671307 |
| EHBP1 | EH domain binding protein 1 | -0.066028 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0612626 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0590286 |
| RPS27A | ribosomal protein S27a | -0.0585708 |
| ACTG1 | actin gamma 1 | -0.0553702 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0537161 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0519277 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0505122 |
| RASAL2 | RAS protein activator like 2 | -0.0487901 |
| RPS8 | ribosomal protein S8 | -0.0486059 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0453087 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0441884 |
| YAP1 | Yes-associated protein 1 | -0.0434245 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0433659 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0417045 |
| NHSL1 | NHS-like 1 | -0.0412838 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0406176 |
| INTS6 | integrator complex subunit 6 | -0.0394378 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0393658 |
| JMJD1C | jumonji domain containing 1C | -0.0385035 |
| ZNF804A | zinc finger protein 804A | -0.0382339 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.037798 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0367685 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0353463 |
| ASPH | aspartate beta-hydroxylase | -0.0349593 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0343886 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0342431 |
| CANX | calnexin | -0.0336761 |
| RPS6 | ribosomal protein S6 | -0.0336477 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0321927 |
| ADIPOR2 | adiponectin receptor 2 | -0.0317594 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.031274 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.031027 |
| RPL35A | ribosomal protein L35a | -0.0307598 |
| RPLP1 | ribosomal protein, large, P1 | -0.0307451 |
| RPL37A | ribosomal protein L37a | -0.0306025 |
| RPLP2 | ribosomal protein, large, P2 | -0.0305991 |
| RPS19 | ribosomal protein S19 | -0.0303888 |
| RPL23 | ribosomal protein L23 | -0.0295822 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0284105 |
| RPS12 | ribosomal protein S12 | -0.0281146 |
| RPL34 | ribosomal protein L34 | -0.0272186 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0271452 |
| PTMA | prothymosin, alpha | -0.0268634 |
| RPL26 | ribosomal protein L26 | -0.0267954 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0267742 |
| GPHN | gephyrin | -0.0266867 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0263277 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0259146 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0254519 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | -0.0253119 |
| RPS29 | ribosomal protein S29 | -0.0252128 |
| NABP1 | nucleic acid binding protein 1 | -0.0252099 |
| RPL19 | ribosomal protein L19 | -0.0251342 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0248741 |
| ENO1 | enolase 1, (alpha) | -0.0245141 |
| RPS3 | ribosomal protein S3 | -0.0243469 |
| CUX1 | cut-like homeobox 1 | -0.0242857 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0240354 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0237909 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0233817 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0231698 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0230555 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0230355 |
| RPL9 | ribosomal protein L9 | -0.0227431 |
| FTL | ferritin, light polypeptide | -0.0224309 |
| LRRC23 | leucine rich repeat containing 23 | -0.0223673 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0222565 |
| PARD3 | par-3 family cell polarity regulator | -0.0222053 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0220913 |
| EXOC4 | exocyst complex component 4 | -0.0220857 |
| NF1 | neurofibromin 1 | -0.0220461 |
| COMMD10 | COMM domain containing 10 | -0.022009 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0218529 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0218149 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0215671 |
| GNAS | GNAS complex locus | -0.021503 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0214566 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0213993 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0212172 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0212066 |
| UBC | ubiquitin C | -0.0210935 |
| ZNF638 | zinc finger protein 638 | -0.0210783 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0210728 |
| R3HDM2 | R3H domain containing 2 | -0.0209966 |
| CEP112 | centrosomal protein 112kDa | -0.020706 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0206615 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0202726 |
| RPL5 | ribosomal protein L5 | -0.0201998 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.020198 |
| VMP1 | vacuole membrane protein 1 | -0.0201221 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0198073 |
