| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (hydrochloride) perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Imiquimod (hydrochloride)_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD4A | FERM domain containing 4A | 0.144934 |
| NAV2 | neuron navigator 2 | 0.0977116 |
| GPC6 | glypican 6 | 0.0855623 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0827924 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0708465 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0694764 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0657805 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.064661 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0601507 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0598621 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0566673 |
| CA12 | carbonic anhydrase XII | 0.056509 |
| SMAD3 | SMAD family member 3 | 0.0531281 |
| NRP2 | neuropilin 2 | 0.0504421 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.047795 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0476621 |
| CALU | calumenin | 0.0458789 |
| VCL | vinculin | 0.045257 |
| PAX8 | paired box 8 | 0.0452222 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0420428 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0419714 |
| CD44 | CD44 molecule (Indian blood group) | 0.0403148 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.038761 |
| AHNAK | AHNAK nucleoprotein | 0.0383124 |
| APOL1 | apolipoprotein L, 1 | 0.0366405 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0362076 |
| APP | amyloid beta (A4) precursor protein | 0.0361763 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0355909 |
| RPL3 | ribosomal protein L3 | 0.0346456 |
| LOXL2 | lysyl oxidase-like 2 | 0.0344907 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0329297 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.03267 |
| FAT1 | FAT atypical cadherin 1 | 0.0316382 |
| PLEC | plectin | 0.0310086 |
| MYOF | myoferlin | 0.0307539 |
| FMNL2 | formin-like 2 | 0.0303937 |
| TPM3 | tropomyosin 3 | 0.0301624 |
| SEPTIN9 | septin 9 | 0.0297504 |
| HDLBP | high density lipoprotein binding protein | 0.0287418 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0286825 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0285747 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0280008 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0276804 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0275044 |
| COL4A1 | collagen, type IV, alpha 1 | 0.026627 |
| ARRDC3 | arrestin domain containing 3 | 0.026464 |
| EGFR | epidermal growth factor receptor | 0.0264064 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0262706 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0260264 |
| RAI14 | retinoic acid induced 14 | 0.0259937 |
| SLTM | SAFB-like, transcription modulator | 0.0257203 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.0252226 |
| TNS3 | tensin 3 | 0.0246703 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0239875 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0235207 |
| FLNA | filamin A, alpha | 0.023354 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0230701 |
| RAD51B | RAD51 paralog B | 0.0228693 |
| FNIP1 | folliculin interacting protein 1 | 0.0228462 |
| NCKAP1 | NCK-associated protein 1 | 0.0227439 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0226819 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.0226484 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0225259 |
| FAM20C | family with sequence similarity 20, member C | 0.0224545 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0222767 |
| CORO1C | coronin, actin binding protein, 1C | 0.0218787 |
| CAPRIN1 | cell cycle associated protein 1 | 0.021856 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0217994 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0217937 |
| MKI67 | marker of proliferation Ki-67 | 0.0216317 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0216196 |
| CDK6 | cyclin-dependent kinase 6 | 0.0215887 |
| FAM114A1 | family with sequence similarity 114, member A1 | 0.0214321 |
| COL5A1 | collagen, type V, alpha 1 | 0.0211393 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0209817 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0208902 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0204416 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0204342 |
| PTK2 | protein tyrosine kinase 2 | 0.0202292 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0202013 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0201378 |
| TNS1 | tensin 1 | 0.0201328 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0199435 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0198846 |
| UBC | ubiquitin C | 0.0198151 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0197518 |
| TPM4 | tropomyosin 4 | 0.0195024 |
| DAPK1 | death-associated protein kinase 1 | 0.0194781 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0193783 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0192793 |
| FN1 | fibronectin 1 | 0.0190691 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0190487 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0190023 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0189066 |
| SORCS2 | sortilin-related VPS10 domain containing receptor 2 | 0.0187559 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 | 0.0187003 |
| FRMD5 | FERM domain containing 5 | 0.0186845 |
| NDRG1 | N-myc downstream regulated 1 | 0.0186669 |
| HDAC9 | histone deacetylase 9 | 0.0186482 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0186129 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.103371 |
| RPS6 | ribosomal protein S6 | -0.0981035 |
| VIM | vimentin | -0.0876679 |
| TMSB10 | thymosin beta 10 | -0.0846218 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0782408 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0639268 |
| RPL35A | ribosomal protein L35a | -0.0531426 |
| RPLP1 | ribosomal protein, large, P1 | -0.0480611 |
| PFN1 | profilin 1 | -0.0444583 |
| RPS8 | ribosomal protein S8 | -0.0436199 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0435066 |
| RPS19 | ribosomal protein S19 | -0.0431265 |
| MT2A | metallothionein 2A | -0.0418308 |
| RPL19 | ribosomal protein L19 | -0.0411735 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0396873 |
| RPLP2 | ribosomal protein, large, P2 | -0.0394519 |
| PTMA | prothymosin, alpha | -0.0367921 |
| TXNRD1 | thioredoxin reductase 1 | -0.0355138 |
| POTEF | POTE ankyrin domain family, member F | -0.0351258 |
| RPL28 | ribosomal protein L28 | -0.0347296 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0343407 |
| RPL9 | ribosomal protein L9 | -0.0325734 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.0320752 |
| RPL26 | ribosomal protein L26 | -0.0312284 |
| RPL35 | ribosomal protein L35 | -0.0306774 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0299345 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0296443 |
| RPL34 | ribosomal protein L34 | -0.029041 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0288777 |
| RPS5 | ribosomal protein S5 | -0.0281568 |
| GDF15 | growth differentiation factor 15 | -0.0280819 |
| RPS20 | ribosomal protein S20 | -0.0280318 |
| RPL37A | ribosomal protein L37a | -0.0279025 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.0275866 |
| HLA-B | major histocompatibility complex, class I, B | -0.0272345 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.027017 |
| RPL36 | ribosomal protein L36 | -0.0267466 |
| RPL31 | ribosomal protein L31 | -0.0266945 |
| RPL12 | ribosomal protein L12 | -0.0264569 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0262892 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0258071 |
| TSC22D2 | TSC22 domain family, member 2 | -0.02529 |
| HMGB1 | high mobility group box 1 | -0.025173 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0251466 |
| RPS27A | ribosomal protein S27a | -0.0250113 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0245455 |
| GNAS | GNAS complex locus | -0.0244092 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0243614 |
| RPL5 | ribosomal protein L5 | -0.0241512 |
| CSF1 | colony stimulating factor 1 (macrophage) | -0.0238723 |
| B2M | beta-2-microglobulin | -0.0234354 |
| RPS12 | ribosomal protein S12 | -0.0230395 |
| RPS14 | ribosomal protein S14 | -0.0227237 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0223733 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0214258 |
| MAP1B | microtubule-associated protein 1B | -0.0213432 |
| S100A6 | S100 calcium binding protein A6 | -0.0213081 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0212642 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0212456 |
| RPS2 | ribosomal protein S2 | -0.0210162 |
| RTN4 | reticulon 4 | -0.0209003 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0208474 |
| RPS24 | ribosomal protein S24 | -0.0203652 |
| RPL30 | ribosomal protein L30 | -0.0202884 |
| RPS21 | ribosomal protein S21 | -0.020283 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0199251 |
| RPL36A | ribosomal protein L36a | -0.0198687 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0198041 |
| CD70 | CD70 molecule | -0.0197957 |
| GOLGA4 | golgin A4 | -0.019732 |
| RPS17 | ribosomal protein S17 | -0.0197281 |
| RPS27 | ribosomal protein S27 | -0.0195418 |
| LDHB | lactate dehydrogenase B | -0.0188854 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0188678 |
| RPS13 | ribosomal protein S13 | -0.0187526 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0187306 |
| MYADM | myeloid-associated differentiation marker | -0.0186671 |
| CXXC1 | CXXC finger protein 1 | -0.0184309 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0182502 |
| RPS3 | ribosomal protein S3 | -0.0181901 |
| ATF4 | activating transcription factor 4 | -0.0180039 |
| RPS16 | ribosomal protein S16 | -0.0179778 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0179511 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0179415 |
| RPL27 | ribosomal protein L27 | -0.0179363 |
| RPS23 | ribosomal protein S23 | -0.0176207 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.0175786 |
| RPLP0 | ribosomal protein, large, P0 | -0.0174789 |
| SEPTIN7 | septin 7 | -0.0174444 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0174093 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.017275 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0172398 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.017209 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0171538 |
| NOP58 | NOP58 ribonucleoprotein | -0.0167855 |
| RPL23 | ribosomal protein L23 | -0.016308 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0162169 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0159589 |
| RBM25 | RNA binding motif protein 25 | -0.0158195 |
| USP3 | ubiquitin specific peptidase 3 | -0.0157111 |
