| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (hydrochloride) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Imiquimod (hydrochloride)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.160242 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.146416 |
| PEG10 | paternally expressed 10 | 0.129389 |
| MEST | mesoderm specific transcript | 0.128823 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0864786 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0691125 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0685738 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0674682 |
| MED13L | mediator complex subunit 13-like | 0.0614415 |
| RPL3 | ribosomal protein L3 | 0.0612327 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0589567 |
| KAZN | kazrin, periplakin interacting protein | 0.0585722 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0546312 |
| CADM2 | cell adhesion molecule 2 | 0.0528371 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0519493 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0504879 |
| QKI | QKI, KH domain containing, RNA binding | 0.0501524 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0490974 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0479184 |
| RACK1 | receptor for activated C kinase 1 | 0.0478496 |
| TPK1 | thiamin pyrophosphokinase 1 | 0.0463864 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0457906 |
| SFTPA2 | surfactant protein A2 | 0.0449188 |
| ATP11A | ATPase, class VI, type 11A | 0.0447793 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0445247 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0441901 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0440865 |
| RNF130 | ring finger protein 130 | 0.0439102 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.0437343 |
| MEOX2 | mesenchyme homeobox 2 | 0.0434159 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0432846 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0427111 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0421161 |
| TUBB | tubulin, beta class I | 0.0420718 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0416032 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0412047 |
| GSE1 | Gse1 coiled-coil protein | 0.0406246 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0400929 |
| SEPTIN11 | septin 11 | 0.0395943 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0395843 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.0393281 |
| PHF21A | PHD finger protein 21A | 0.0372753 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.037264 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0365295 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0364967 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0363929 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0363874 |
| PLS3 | plastin 3 | 0.0361544 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0359638 |
| HOXC10 | homeobox C10 | 0.0356031 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0353031 |
| PCM1 | pericentriolar material 1 | 0.0350332 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0350111 |
| RREB1 | ras responsive element binding protein 1 | 0.0347157 |
| CCNY | cyclin Y | 0.034667 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0346528 |
| FAM13A | family with sequence similarity 13, member A | 0.0344536 |
| FLNA | filamin A, alpha | 0.0339559 |
| CANX | calnexin | 0.0337118 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0333354 |
| PHF3 | PHD finger protein 3 | 0.0331783 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0330435 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0330361 |
| CTBP2 | C-terminal binding protein 2 | 0.0330122 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0327849 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0324134 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0322505 |
| NCKAP1 | NCK-associated protein 1 | 0.0318525 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0315053 |
| VIM | vimentin | 0.0313472 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0310739 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | 0.0310631 |
| DMXL1 | Dmx-like 1 | 0.030921 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0305197 |
| PRLR | prolactin receptor | 0.0303727 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0301856 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0300802 |
| YY1 | YY1 transcription factor | 0.030045 |
| RPL4 | ribosomal protein L4 | 0.0300279 |
| CHKA | choline kinase alpha | 0.0297767 |
| NFIB | nuclear factor I/B | 0.0297722 |
| FKBP5 | FK506 binding protein 5 | 0.0296855 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.029656 |
| UBXN7 | UBX domain protein 7 | 0.0295039 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0294908 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0293619 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0292627 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0292575 |
| IGF2R | insulin-like growth factor 2 receptor | 0.028916 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0287348 |
| KIF1A | kinesin family member 1A | 0.028546 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0281993 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0281584 |
| EXOC4 | exocyst complex component 4 | 0.0280848 |
| PRRC2A | proline-rich coiled-coil 2A | 0.028017 |
| JMJD1C | jumonji domain containing 1C | 0.0278451 |
| FBN1 | fibrillin 1 | 0.0278342 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0276653 |
| ZNF638 | zinc finger protein 638 | 0.0276259 |
| CRY1 | cryptochrome circadian clock 1 | 0.0276222 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.125197 |
| RPS6 | ribosomal protein S6 | -0.0889229 |
| RPS2 | ribosomal protein S2 | -0.0816672 |
| MT2A | metallothionein 2A | -0.0776989 |
| PTMA | prothymosin, alpha | -0.0775005 |
| RPS8 | ribosomal protein S8 | -0.0608402 |
| CENPF | centromere protein F, 350/400kDa | -0.0607341 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0539983 |
| RPL34 | ribosomal protein L34 | -0.0525998 |
| HMGB2 | high mobility group box 2 | -0.0485023 |
| CENPE | centromere protein E, 312kDa | -0.0470406 |
| RPS23 | ribosomal protein S23 | -0.0461041 |
| RPLP1 | ribosomal protein, large, P1 | -0.0452555 |
| RPS19 | ribosomal protein S19 | -0.0431302 |
| IER3 | immediate early response 3 | -0.0423384 |
| SPAG9 | sperm associated antigen 9 | -0.0415641 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0414946 |
| RPS12 | ribosomal protein S12 | -0.0412574 |
| RPL37A | ribosomal protein L37a | -0.0407493 |
| RPL38 | ribosomal protein L38 | -0.0397949 |
| RPL36 | ribosomal protein L36 | -0.0391432 |
| RPL31 | ribosomal protein L31 | -0.0390087 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0377445 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0366496 |
| GLG1 | golgi glycoprotein 1 | -0.0359925 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0359579 |
| RPS29 | ribosomal protein S29 | -0.0359186 |
| RAD21 | RAD21 homolog (S. pombe) | -0.035813 |
| FN1 | fibronectin 1 | -0.0354244 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0350355 |
| RPL35A | ribosomal protein L35a | -0.0349201 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0344354 |
| RPL28 | ribosomal protein L28 | -0.0343815 |
| SBF2 | SET binding factor 2 | -0.0338104 |
| RPL12 | ribosomal protein L12 | -0.0330403 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0328131 |
| RPS3 | ribosomal protein S3 | -0.0321788 |
| RPL26 | ribosomal protein L26 | -0.032132 |
| RPS25 | ribosomal protein S25 | -0.0312215 |
| RPL9 | ribosomal protein L9 | -0.0309833 |
| H1-4 | H1.4 linker histone, cluster member | -0.0303589 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0301216 |
| RPL19 | ribosomal protein L19 | -0.029594 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0295142 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0294414 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0293068 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0293066 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0285342 |
| RPS10 | ribosomal protein S10 | -0.0282398 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0278028 |
| ASPH | aspartate beta-hydroxylase | -0.0269792 |
| RPS27A | ribosomal protein S27a | -0.0265121 |
| TMSB10 | thymosin beta 10 | -0.0263567 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.026069 |
| NUMB | numb homolog (Drosophila) | -0.025329 |
| USP34 | ubiquitin specific peptidase 34 | -0.0252386 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0248661 |
| PDE10A | phosphodiesterase 10A | -0.024579 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0245485 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0244669 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0241809 |
| LMO4 | LIM domain only 4 | -0.0238368 |
| PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 | -0.0238052 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0237629 |
| MALSU1 | mitochondrial assembly of ribosomal large subunit 1 | -0.0237628 |
| RPS15 | ribosomal protein S15 | -0.0236363 |
| TPX2 | TPX2, microtubule-associated | -0.0235391 |
| RPL5 | ribosomal protein L5 | -0.0230759 |
| RPS21 | ribosomal protein S21 | -0.02304 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0228596 |
| IPMK | inositol polyphosphate multikinase | -0.0227575 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0225582 |
| MORF4L2 | mortality factor 4 like 2 | -0.0224607 |
| HECTD4 | HECT domain containing E3 ubiquitin protein ligase 4 | -0.0224213 |
| VIRMA | vir like m6A methyltransferase associated | -0.0223676 |
| RPAP2 | RNA polymerase II associated protein 2 | -0.022257 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.022194 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0221645 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | -0.022122 |
| USP3 | ubiquitin specific peptidase 3 | -0.021915 |
| EXOC6B | exocyst complex component 6B | -0.021893 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0218685 |
| RPS16 | ribosomal protein S16 | -0.0217826 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0215478 |
| SP3 | Sp3 transcription factor | -0.0214646 |
| EPS15 | epidermal growth factor receptor pathway substrate 15 | -0.0214121 |
| STC1 | stanniocalcin 1 | -0.0214092 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0213975 |
| CCNG1 | cyclin G1 | -0.0213836 |
| DOCK3 | dedicator of cytokinesis 3 | -0.0213727 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0213503 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0212901 |
| SLF2 | SMC5-SMC6 complex localization factor 2 | -0.0211994 |
| TMPO | thymopoietin | -0.0211095 |
| ZRANB3 | zinc finger, RAN-binding domain containing 3 | -0.0210997 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0210068 |
| S100A9 | S100 calcium binding protein A9 | -0.0208752 |
| CEP152 | centrosomal protein 152kDa | -0.0208064 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0207933 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0205669 |
