| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (hydrochloride) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Imiquimod (hydrochloride)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NCOA3 | nuclear receptor coactivator 3 | 0.0365794 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0352048 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0314625 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | 0.0285794 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0271794 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0233695 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0228458 |
| CLTC | clathrin, heavy chain (Hc) | 0.0214543 |
| LASP1 | LIM and SH3 protein 1 | 0.0212139 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0203471 |
| NDRG1 | N-myc downstream regulated 1 | 0.0200539 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0196258 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0195218 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0182986 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0174245 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0169319 |
| FOXO3 | forkhead box O3 | 0.0164725 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0163381 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0163315 |
| CD24 | CD24 molecule | 0.0162092 |
| CEP250 | centrosomal protein 250kDa | 0.0161768 |
| PLEC | plectin | 0.0154737 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0153224 |
| UBC | ubiquitin C | 0.0151508 |
| DHFR | dihydrofolate reductase | 0.0147611 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0147602 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.014401 |
| VCL | vinculin | 0.0143203 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.014123 |
| FAM168A | family with sequence similarity 168, member A | 0.0136879 |
| MLPH | melanophilin | 0.0136786 |
| KIF1A | kinesin family member 1A | 0.0131936 |
| YPEL2 | yippee-like 2 (Drosophila) | 0.0131642 |
| SMAD3 | SMAD family member 3 | 0.0128069 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0126217 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0124874 |
| FNBP1L | formin binding protein 1-like | 0.0124468 |
| GSE1 | Gse1 coiled-coil protein | 0.0124467 |
| MYOF | myoferlin | 0.0122077 |
| TOM1L1 | target of myb1 (chicken)-like 1 | 0.012081 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0119577 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0119553 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0119348 |
| ORMDL3 | ORMDL sphingolipid biosynthesis regulator 3 | 0.0119237 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.011641 |
| HELZ | helicase with zinc finger | 0.0114944 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0114119 |
| AHNAK | AHNAK nucleoprotein | 0.0113889 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0111951 |
| MYO5B | myosin VB | 0.0111651 |
| APP | amyloid beta (A4) precursor protein | 0.0111558 |
| NCKAP1 | NCK-associated protein 1 | 0.0111014 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0110222 |
| EZR | ezrin | 0.010902 |
| TPM3 | tropomyosin 3 | 0.0108895 |
| CFB | complement factor B | 0.0107374 |
| KIF16B | kinesin family member 16B | 0.0107236 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0106842 |
| KIAA1217 | KIAA1217 | 0.0106195 |
| FAM219A | family with sequence similarity 219, member A | 0.0105581 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0105327 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.010434 |
| FAM13A | family with sequence similarity 13, member A | 0.0103573 |
| FLNA | filamin A, alpha | 0.0102661 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0102501 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.010242 |
| CD164 | CD164 molecule, sialomucin | 0.0102051 |
| RPL3 | ribosomal protein L3 | 0.0100609 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0100575 |
| GSDMB | gasdermin B | 0.00975825 |
| XPO1 | exportin 1 | 0.00972685 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.00961313 |
| TSPAN15 | tetraspanin 15 | 0.00952759 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.00950119 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00943288 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.00942907 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.00929535 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 0.00925959 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0092114 |
| CTTN | cortactin | 0.00915472 |
| DUSP16 | dual specificity phosphatase 16 | 0.00908265 |
| ECT2 | epithelial cell transforming 2 | 0.00906942 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.00902896 |
| SMYD3 | SET and MYND domain containing 3 | 0.00896278 |
| TENM2 | teneurin transmembrane protein 2 | 0.00892978 |
| ANXA5 | annexin A5 | 0.00879234 |
| TMEM41B | transmembrane protein 41B | 0.00871525 |
| CLIC4 | chloride intracellular channel 4 | 0.00868102 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.00867527 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.00861748 |
| KAZN | kazrin, periplakin interacting protein | 0.00857132 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.00852746 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.00844179 |
| FBXO32 | F-box protein 32 | 0.00841644 |
| NIBAN2 | niban apoptosis regulator 2 | 0.00834191 |
| PDLIM5 | PDZ and LIM domain 5 | 0.00831698 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.00828912 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.0081715 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.00813856 |
| ECE1 | endothelin converting enzyme 1 | 0.00812403 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL19 | ribosomal protein L19 | -0.152187 |
| RPL23 | ribosomal protein L23 | -0.145733 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0487018 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0419884 |
| RPL35A | ribosomal protein L35a | -0.0366483 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0354232 |
| TMSB10 | thymosin beta 10 | -0.0350446 |
| RPL12 | ribosomal protein L12 | -0.0306365 |
| RPS3 | ribosomal protein S3 | -0.0304193 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0282879 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0282419 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0274288 |
| RPS19 | ribosomal protein S19 | -0.0268999 |
| ACTG1 | actin gamma 1 | -0.0246711 |
| RPS8 | ribosomal protein S8 | -0.024314 |
| PTMA | prothymosin, alpha | -0.0225305 |
| RPL35 | ribosomal protein L35 | -0.0216269 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0207361 |
| RPS6 | ribosomal protein S6 | -0.0206205 |
| CDK12 | cyclin-dependent kinase 12 | -0.0202109 |
| PRRC2C | proline-rich coiled-coil 2C | -0.019852 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0197632 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0196224 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0192588 |
| RPS12 | ribosomal protein S12 | -0.019249 |
| RPS29 | ribosomal protein S29 | -0.0187546 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0183238 |
| RPL37A | ribosomal protein L37a | -0.0179667 |
| RPLP1 | ribosomal protein, large, P1 | -0.0177888 |
| RPL37 | ribosomal protein L37 | -0.0175357 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0162767 |
| RPS14 | ribosomal protein S14 | -0.0156294 |
| RPL34 | ribosomal protein L34 | -0.0155849 |
| NTN4 | netrin 4 | -0.0155474 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0155353 |
| JMJD1C | jumonji domain containing 1C | -0.0149697 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0148308 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0145107 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0143911 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.014297 |
| FTL | ferritin, light polypeptide | -0.0142311 |
| BPTF | bromodomain PHD finger transcription factor | -0.014182 |
| ASPH | aspartate beta-hydroxylase | -0.0139993 |
| ANKRD12 | ankyrin repeat domain 12 | -0.013866 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0137774 |
| MT2A | metallothionein 2A | -0.013664 |
| RPL9 | ribosomal protein L9 | -0.0134241 |
| S100P | S100 calcium binding protein P | -0.0131426 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0129427 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0129145 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0128597 |
| PFN1 | profilin 1 | -0.0128577 |
| RPL31 | ribosomal protein L31 | -0.012364 |
| B2M | beta-2-microglobulin | -0.0123529 |
| PFDN4 | prefoldin subunit 4 | -0.0122638 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0122523 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0122235 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0122197 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0121802 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 | -0.0121262 |
| TTC6 | tetratricopeptide repeat domain 6 | -0.012111 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0120512 |
| RPS24 | ribosomal protein S24 | -0.0120311 |
| RPL36 | ribosomal protein L36 | -0.0120127 |
| RPLP2 | ribosomal protein, large, P2 | -0.0118179 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.011678 |
| EFNA5 | ephrin-A5 | -0.0116691 |
| PSMB3 | proteasome (prosome, macropain) subunit, beta type, 3 | -0.0116523 |
| RPS27 | ribosomal protein S27 | -0.0115954 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0114766 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0112715 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0112643 |
| RPL26 | ribosomal protein L26 | -0.0112626 |
| SON | SON DNA binding protein | -0.0112429 |
| RPS16 | ribosomal protein S16 | -0.0112398 |
| SP100 | SP100 nuclear antigen | -0.0112152 |
| RPS13 | ribosomal protein S13 | -0.0111966 |
| COX8A | cytochrome c oxidase subunit VIIIA (ubiquitous) | -0.0111927 |
| RPL8 | ribosomal protein L8 | -0.0111604 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0111142 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0110863 |
| INSR | insulin receptor | -0.0110562 |
| HLA-B | major histocompatibility complex, class I, B | -0.0110281 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0109988 |
| RPL28 | ribosomal protein L28 | -0.010787 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0106969 |
| PABPN1 | poly(A) binding protein, nuclear 1 | -0.0106771 |
| MYL12B | myosin, light chain 12B, regulatory | -0.010583 |
| RPS17 | ribosomal protein S17 | -0.0105499 |
| GLCCI1 | glucocorticoid induced 1 | -0.0104435 |
| RPL30 | ribosomal protein L30 | -0.0103683 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0103612 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0103036 |
| RPLP0 | ribosomal protein, large, P0 | -0.0102972 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0101773 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0100141 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.00993985 |
| FAU | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | -0.00989907 |
| RPL7A | ribosomal protein L7a | -0.00978861 |
| PMP22 | peripheral myelin protein 22 | -0.00968141 |
