| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (hydrochloride) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Imiquimod (hydrochloride)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.258478 |
| VGF | VGF nerve growth factor inducible | 0.0806601 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0645226 |
| CD109 | CD109 molecule | 0.0548315 |
| TNNC1 | troponin C type 1 (slow) | 0.052738 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0523216 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0446811 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0439784 |
| RNF145 | ring finger protein 145 | 0.0430954 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0427148 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0424778 |
| CDC73 | cell division cycle 73 | 0.0410899 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0392326 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0389567 |
| APP | amyloid beta (A4) precursor protein | 0.0384731 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0372378 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0371213 |
| NAV2 | neuron navigator 2 | 0.0360957 |
| ZYX | zyxin | 0.0359078 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0348558 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0346577 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0341596 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0337606 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.033138 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0325748 |
| A2M | alpha-2-macroglobulin | 0.0321513 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0304799 |
| PRELID2 | PRELI domain containing 2 | 0.0304743 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0301703 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0300853 |
| FBXO7 | F-box protein 7 | 0.0291123 |
| PI15 | peptidase inhibitor 15 | 0.0289754 |
| RPL3 | ribosomal protein L3 | 0.028942 |
| HELZ | helicase with zinc finger | 0.0285666 |
| RBM33 | RNA binding motif protein 33 | 0.0282267 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0280594 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0268172 |
| NBAS | neuroblastoma amplified sequence | 0.0265441 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0263398 |
| SDC2 | syndecan 2 | 0.0262069 |
| ARRDC3 | arrestin domain containing 3 | 0.0259072 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.025889 |
| SMAD3 | SMAD family member 3 | 0.0247608 |
| MKRN1 | makorin ring finger protein 1 | 0.0245583 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0243432 |
| ANXA5 | annexin A5 | 0.0238686 |
| AHR | aryl hydrocarbon receptor | 0.0234365 |
| PKM | pyruvate kinase, muscle | 0.0231586 |
| DST | dystonin | 0.0231389 |
| FLNA | filamin A, alpha | 0.0229182 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0228347 |
| CHSY1 | chondroitin sulfate synthase 1 | 0.0225168 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0222323 |
| INSIG2 | insulin induced gene 2 | 0.0220539 |
| UBC | ubiquitin C | 0.0219612 |
| RHEB | Ras homolog enriched in brain | 0.0217533 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.021748 |
| MRTFA | myocardin related transcription factor A | 0.0217419 |
| RTN4 | reticulon 4 | 0.0216987 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0210868 |
| PGK1 | phosphoglycerate kinase 1 | 0.0207528 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0206417 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0203774 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0202994 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0201202 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 | 0.0196542 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0195098 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0193299 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0189129 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0186741 |
| NCKAP1 | NCK-associated protein 1 | 0.0186308 |
| GAS7 | growth arrest-specific 7 | 0.0184777 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0182834 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0179775 |
| PUM2 | pumilio RNA-binding family member 2 | 0.017582 |
| CNN3 | calponin 3, acidic | 0.0173952 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0172782 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0172694 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.017228 |
| ACTN1 | actinin, alpha 1 | 0.0170606 |
| SFTPA2 | surfactant protein A2 | 0.0168008 |
| AHNAK | AHNAK nucleoprotein | 0.0167805 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0166889 |
| VMP1 | vacuole membrane protein 1 | 0.0165817 |
| ZNF608 | zinc finger protein 608 | 0.0163708 |
| TRIB1 | tribbles pseudokinase 1 | 0.016234 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0160897 |
| FOXJ3 | forkhead box J3 | 0.0160369 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0157435 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0157128 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0156567 |
| RANBP2 | RAN binding protein 2 | 0.0155456 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0154959 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0154214 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0153123 |
| CALU | calumenin | 0.0152887 |
| CORO1C | coronin, actin binding protein, 1C | 0.0152677 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0151033 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.015045 |
| DHFR | dihydrofolate reductase | 0.0150428 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0909379 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0873497 |
| VIM | vimentin | -0.0867678 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0860202 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0837002 |
| NLGN1 | neuroligin 1 | -0.0711012 |
| GPC6 | glypican 6 | -0.0664351 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0609937 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0608149 |
| TMSB10 | thymosin beta 10 | -0.0528727 |
| EHBP1 | EH domain binding protein 1 | -0.0449282 |
| S100A6 | S100 calcium binding protein A6 | -0.0439191 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0419823 |
| HLA-B | major histocompatibility complex, class I, B | -0.0418168 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0400313 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0398399 |
| OXR1 | oxidation resistance 1 | -0.0372519 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0350474 |
| RUNX1 | runt-related transcription factor 1 | -0.0350186 |
| RPLP1 | ribosomal protein, large, P1 | -0.0349333 |
| ACTG1 | actin gamma 1 | -0.0348503 |
| EGR1 | early growth response 1 | -0.0344843 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0334647 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0333048 |
| IER3 | immediate early response 3 | -0.0326479 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0323411 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0305079 |
| SCFD2 | sec1 family domain containing 2 | -0.0304874 |
| LRRC23 | leucine rich repeat containing 23 | -0.03021 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0299717 |
| CDK14 | cyclin-dependent kinase 14 | -0.0285844 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0283513 |
| RNF24 | ring finger protein 24 | -0.0271873 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0271615 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.027155 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0269757 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0267905 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0266365 |
| PCDH7 | protocadherin 7 | -0.0264298 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0259421 |
| MACROD2 | MACRO domain containing 2 | -0.0248637 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0246123 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0244067 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0243421 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0240122 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0239939 |
| FBXO11 | F-box protein 11 | -0.02361 |
| MYO1E | myosin IE | -0.0233576 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0232678 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0231713 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0229097 |
| JMJD1C | jumonji domain containing 1C | -0.0229028 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0226111 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0221653 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0217371 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0213537 |
| CALD1 | caldesmon 1 | -0.0213109 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.0206176 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0205907 |
| GNAS | GNAS complex locus | -0.0201978 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0201571 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.019998 |
| HMGA2 | high mobility group AT-hook 2 | -0.0198136 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0196597 |
| GLG1 | golgi glycoprotein 1 | -0.0194124 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0194043 |
| EXOC4 | exocyst complex component 4 | -0.0192696 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0191495 |
| ZNF704 | zinc finger protein 704 | -0.0191215 |
| NEGR1 | neuronal growth regulator 1 | -0.0190697 |
| NAV3 | neuron navigator 3 | -0.0190291 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0188292 |
| DIAPH2 | diaphanous-related formin 2 | -0.0186853 |
| MEIS2 | Meis homeobox 2 | -0.0185953 |
| RPS8 | ribosomal protein S8 | -0.0183774 |
| JUN | jun proto-oncogene | -0.0182432 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0179303 |
| RPL35A | ribosomal protein L35a | -0.0176478 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0176118 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0175289 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0175243 |
| S100A9 | S100 calcium binding protein A9 | -0.0174653 |
| TLE4 | transducin-like enhancer of split 4 | -0.0174625 |
| RPS6 | ribosomal protein S6 | -0.0172371 |
| PTMA | prothymosin, alpha | -0.0171911 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.017161 |
| CUX1 | cut-like homeobox 1 | -0.0170912 |
| FRMD5 | FERM domain containing 5 | -0.0169443 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.016751 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0167456 |
| RPS12 | ribosomal protein S12 | -0.0166548 |
| AEBP2 | AE binding protein 2 | -0.0162814 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0157658 |
| RBM25 | RNA binding motif protein 25 | -0.0156777 |
| PTCHD4 | patched domain containing 4 | -0.0156181 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0155142 |
| MTDH | metadherin | -0.015513 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0155092 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | -0.0154782 |
| RPL37A | ribosomal protein L37a | -0.0151698 |
