| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (hydrochloride) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Imiquimod (hydrochloride)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0833777 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0802372 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0724171 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0699106 |
| TMSB4X | thymosin beta 4, X-linked | 0.0669698 |
| POTEF | POTE ankyrin domain family, member F | 0.0574706 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0501976 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0469307 |
| MEF2A | myocyte enhancer factor 2A | 0.0447626 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0415842 |
| NUP58 | nucleoporin 58 | 0.0400019 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0398677 |
| CCNL1 | cyclin L1 | 0.0396877 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0373831 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0366876 |
| UBC | ubiquitin C | 0.0350065 |
| SPAG9 | sperm associated antigen 9 | 0.0337455 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0331369 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0327157 |
| MT1X | metallothionein 1X | 0.0323734 |
| RPL3 | ribosomal protein L3 | 0.0322844 |
| PLAU | plasminogen activator, urokinase | 0.0317601 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0311141 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0307003 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0304642 |
| FOSL1 | FOS-like antigen 1 | 0.0304241 |
| EZR | ezrin | 0.0289273 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0287997 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0283858 |
| NDRG1 | N-myc downstream regulated 1 | 0.0283091 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0280715 |
| FLNA | filamin A, alpha | 0.0275135 |
| CASC3 | cancer susceptibility candidate 3 | 0.0262337 |
| KLF6 | Kruppel-like factor 6 | 0.0262135 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0261173 |
| TPM3 | tropomyosin 3 | 0.0260882 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0256223 |
| SMAD3 | SMAD family member 3 | 0.0255231 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0253052 |
| ABI1 | abl-interactor 1 | 0.0249059 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.024613 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0244516 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0241695 |
| TFG | TRK-fused gene | 0.0237445 |
| FAM13A | family with sequence similarity 13, member A | 0.0236197 |
| ARRDC3 | arrestin domain containing 3 | 0.0234676 |
| RACK1 | receptor for activated C kinase 1 | 0.0229156 |
| SNX9 | sorting nexin 9 | 0.0228142 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0224109 |
| DDX52 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 | 0.0220702 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0219331 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0218218 |
| IRF6 | interferon regulatory factor 6 | 0.0218141 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0214512 |
| YBX1 | Y box binding protein 1 | 0.0212852 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0210106 |
| TSC22D2 | TSC22 domain family, member 2 | 0.020939 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | 0.0205196 |
| YTHDC1 | YTH domain containing 1 | 0.0201502 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0201484 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0200325 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0197833 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0197671 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0197301 |
| PNN | pinin, desmosome associated protein | 0.0193265 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0193221 |
| PEG10 | paternally expressed 10 | 0.0192036 |
| NCKAP1 | NCK-associated protein 1 | 0.0191746 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0189981 |
| G0S2 | G0/G1 switch 2 | 0.018869 |
| INSIG2 | insulin induced gene 2 | 0.0187695 |
| TOP1 | topoisomerase (DNA) I | 0.0186228 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0185828 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0185148 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0184857 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0184807 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0183758 |
| RASA2 | RAS p21 protein activator 2 | 0.0179808 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0179136 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0176233 |
| KRT18 | keratin 18, type I | 0.0176011 |
| RPL4 | ribosomal protein L4 | 0.0174884 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0174333 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0171163 |
| ATP13A3 | ATPase type 13A3 | 0.0168476 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0167469 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0163535 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0162813 |
| MCL1 | myeloid cell leukemia 1 | 0.0162792 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0162736 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0159525 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0159295 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 0.0155547 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.015523 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0154718 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0153863 |
| FAM162A | family with sequence similarity 162, member A | 0.0153381 |
| TUBB | tubulin, beta class I | 0.0152405 |
| CD83 | CD83 molecule | 0.0151446 |
| AFDN | afadin, adherens junction formation factor | 0.01511 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HLA-B | major histocompatibility complex, class I, B | -0.111257 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0984572 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0974317 |
| CP | ceruloplasmin (ferroxidase) | -0.0931356 |
| MMP7 | matrix metallopeptidase 7 | -0.0917092 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0895974 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0719108 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0711724 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0669002 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.062055 |
| EFNA5 | ephrin-A5 | -0.0614165 |
| VIM | vimentin | -0.0608295 |
| TMSB10 | thymosin beta 10 | -0.0593462 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0586173 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0542917 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.054203 |
| FTL | ferritin, light polypeptide | -0.0540253 |
| SP100 | SP100 nuclear antigen | -0.052478 |
| RNF213 | ring finger protein 213 | -0.0514083 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0509917 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0502929 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0496083 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0485348 |
| RPL35A | ribosomal protein L35a | -0.048177 |
| APOL1 | apolipoprotein L, 1 | -0.0453002 |
| RPS29 | ribosomal protein S29 | -0.044895 |
| MX1 | MX dynamin-like GTPase 1 | -0.0443817 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0433013 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0424178 |
| NRG3 | neuregulin 3 | -0.0422295 |
| PCDH7 | protocadherin 7 | -0.0421507 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.03962 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0387573 |
| MT2A | metallothionein 2A | -0.0383517 |
| MX2 | MX dynamin-like GTPase 2 | -0.0380384 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0376956 |
| KRT19 | keratin 19, type I | -0.0374087 |
| RAD51B | RAD51 paralog B | -0.0372539 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0372328 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0372001 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0369374 |
| ATXN1 | ataxin 1 | -0.0368192 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.036694 |
| FNDC3B | fibronectin type III domain containing 3B | -0.036276 |
| S100A10 | S100 calcium binding protein A10 | -0.036007 |
| PARD3 | par-3 family cell polarity regulator | -0.0359292 |
| PRKCA | protein kinase C, alpha | -0.0358271 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0356391 |
| NABP1 | nucleic acid binding protein 1 | -0.0352994 |
| MYO1E | myosin IE | -0.0352812 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0351441 |
| HLA-E | major histocompatibility complex, class I, E | -0.0345489 |
| TMC5 | transmembrane channel-like 5 | -0.0341564 |
| RPLP1 | ribosomal protein, large, P1 | -0.0340472 |
| S100A6 | S100 calcium binding protein A6 | -0.0337797 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0335468 |
| LMO7 | LIM domain 7 | -0.0334282 |
| RUNX1 | runt-related transcription factor 1 | -0.0333585 |
| PKM | pyruvate kinase, muscle | -0.0333486 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0333246 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0331362 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0327385 |
| RIGI | RNA sensor RIG-I | -0.0326324 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0325356 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0323828 |
| PTMA | prothymosin, alpha | -0.0322716 |
| ENO1 | enolase 1, (alpha) | -0.0321535 |
| DST | dystonin | -0.0318895 |
| LAMB3 | laminin, beta 3 | -0.0314833 |
| ANXA2 | annexin A2 | -0.0313717 |
| RPL34 | ribosomal protein L34 | -0.0313386 |
| MT1E | metallothionein 1E | -0.0311789 |
| GOLGB1 | golgin B1 | -0.0311191 |
| HMGA2 | high mobility group AT-hook 2 | -0.0309597 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0309339 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0308955 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0303962 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0303049 |
| RPL31 | ribosomal protein L31 | -0.0302464 |
| PMP22 | peripheral myelin protein 22 | -0.0300772 |
| B2M | beta-2-microglobulin | -0.0300571 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0300258 |
| FBXO11 | F-box protein 11 | -0.0295792 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0295417 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0294784 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.02932 |
| RPS8 | ribosomal protein S8 | -0.0289287 |
| MCU | mitochondrial calcium uniporter | -0.0286504 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0285677 |
| RPL19 | ribosomal protein L19 | -0.028327 |
| NPAS2 | neuronal PAS domain protein 2 | -0.02827 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0281693 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.028006 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0279163 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.027835 |
| RASAL2 | RAS protein activator like 2 | -0.0277502 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0274575 |
| RAB7A | RAB7A, member RAS oncogene family | -0.027233 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0272309 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0271995 |
