| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (hydrochloride) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Imiquimod (hydrochloride)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.144791 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0954984 |
| NRG1 | neuregulin 1 | 0.0949916 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0933502 |
| MSI2 | musashi RNA-binding protein 2 | 0.0927689 |
| IGF2 | insulin-like growth factor 2 | 0.0912218 |
| VCL | vinculin | 0.0806546 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0668046 |
| COL3A1 | collagen, type III, alpha 1 | 0.0647696 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0638792 |
| GPC5 | glypican 5 | 0.0620769 |
| RPL4 | ribosomal protein L4 | 0.0620489 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0585014 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0568801 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0568217 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0556868 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.0555062 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0518345 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0491882 |
| WAC | WW domain containing adaptor with coiled-coil | 0.047228 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0443997 |
| RACK1 | receptor for activated C kinase 1 | 0.0429724 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0425241 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0420648 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0419932 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0419414 |
| VMP1 | vacuole membrane protein 1 | 0.0403282 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0400769 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0395252 |
| SEPTIN9 | septin 9 | 0.0384122 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0381902 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0378696 |
| SEPTIN2 | septin 2 | 0.0375246 |
| RPL3 | ribosomal protein L3 | 0.0374321 |
| APP | amyloid beta (A4) precursor protein | 0.037279 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0362345 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0361783 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0359898 |
| ENAH | enabled homolog (Drosophila) | 0.034696 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0340969 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | 0.0340732 |
| RPL23 | ribosomal protein L23 | 0.033103 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.0328007 |
| WDR43 | WD repeat domain 43 | 0.0322161 |
| NCKAP1 | NCK-associated protein 1 | 0.0321871 |
| DHFR | dihydrofolate reductase | 0.0321267 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0317452 |
| COPA | coatomer protein complex, subunit alpha | 0.0315059 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0314254 |
| HELZ | helicase with zinc finger | 0.0313693 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0311866 |
| AUTS2 | autism susceptibility candidate 2 | 0.0310762 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0310318 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.031026 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0306917 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0302414 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0298852 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0286778 |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha | 0.0284863 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0282933 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.0282351 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0280324 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0279576 |
| DENND1A | DENN/MADD domain containing 1A | 0.0278014 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0277789 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0276909 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.0276319 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0273017 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0269254 |
| DTNA | dystrobrevin, alpha | 0.0266871 |
| SPOP | speckle-type POZ protein | 0.0263091 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0259051 |
| YBX1 | Y box binding protein 1 | 0.0257509 |
| HMBOX1 | homeobox containing 1 | 0.0256182 |
| PTMA | prothymosin, alpha | 0.0255207 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.0254 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | 0.0252791 |
| FDXR | ferredoxin reductase | 0.0252328 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0250348 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0249479 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0249388 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.0248615 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0247438 |
| FAM13A | family with sequence similarity 13, member A | 0.0246683 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0245972 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.0245098 |
| RNF145 | ring finger protein 145 | 0.0244695 |
| EP400 | E1A binding protein p400 | 0.0244462 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0244223 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0244006 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0243724 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0243395 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0242788 |
| MYO6 | myosin VI | 0.0238547 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0238081 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0237454 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0232687 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0231755 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0231702 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0231467 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.175549 |
| MEIS2 | Meis homeobox 2 | -0.113352 |
| RPS6 | ribosomal protein S6 | -0.0858235 |
| SYT1 | synaptotagmin I | -0.0773572 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0769343 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.074617 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0598867 |
| BPTF | bromodomain PHD finger transcription factor | -0.057287 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.056767 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0542154 |
| CENPF | centromere protein F, 350/400kDa | -0.0534893 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0519181 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0491298 |
| SPAG9 | sperm associated antigen 9 | -0.0483951 |
| RPS2 | ribosomal protein S2 | -0.0479588 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.046746 |
| CENPE | centromere protein E, 312kDa | -0.0451855 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0443234 |
| RPL38 | ribosomal protein L38 | -0.0413643 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0411953 |
| GLG1 | golgi glycoprotein 1 | -0.0409882 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0402242 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0401508 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0393744 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0379998 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0373194 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0369554 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0367345 |
| FNBP1 | formin binding protein 1 | -0.0364738 |
| ASPH | aspartate beta-hydroxylase | -0.0355209 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0353906 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0352541 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0352307 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0350231 |
| ACTG1 | actin gamma 1 | -0.0347996 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0345702 |
| GOLGA4 | golgin A4 | -0.0342446 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.033867 |
| RUNX1 | runt-related transcription factor 1 | -0.0338633 |
| BBX | bobby sox homolog (Drosophila) | -0.0337554 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.032617 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0326016 |
| SON | SON DNA binding protein | -0.0324029 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0323512 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0322284 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | -0.0321538 |
| EXOC6B | exocyst complex component 6B | -0.0321503 |
| MKI67 | marker of proliferation Ki-67 | -0.03203 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.0314151 |
| RTN4 | reticulon 4 | -0.0312249 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.03108 |
| PRR11 | proline rich 11 | -0.0309796 |
| CLASP2 | cytoplasmic linker associated protein 2 | -0.0307548 |
| RPL19 | ribosomal protein L19 | -0.030608 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0302057 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0295195 |
| RPLP1 | ribosomal protein, large, P1 | -0.0294868 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0293455 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0293428 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.028857 |
| RPS29 | ribosomal protein S29 | -0.0286953 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.028466 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0282826 |
| FHIT | fragile histidine triad | -0.0282482 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0281647 |
| JMJD1C | jumonji domain containing 1C | -0.0281373 |
| RPL36 | ribosomal protein L36 | -0.0280301 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0280186 |
| TXNIP | thioredoxin interacting protein | -0.0274897 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0270378 |
| CD44 | CD44 molecule (Indian blood group) | -0.0264796 |
| PDE10A | phosphodiesterase 10A | -0.0263663 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0261211 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0259002 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0257317 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0257312 |
| PRTG | protogenin | -0.0257302 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0255871 |
| RPL37A | ribosomal protein L37a | -0.0251745 |
| ANO6 | anoctamin 6 | -0.0251476 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0249943 |
| CEP112 | centrosomal protein 112kDa | -0.0249081 |
| EDEM3 | ER degradation enhancer, mannosidase alpha-like 3 | -0.0247121 |
| RIGI | RNA sensor RIG-I | -0.024411 |
| MTDH | metadherin | -0.0241318 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0238921 |
| MYH10 | myosin, heavy chain 10, non-muscle | -0.0236843 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.02363 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | -0.0236204 |
| LYPLAL1 | lysophospholipase-like 1 | -0.0236179 |
| RNF150 | ring finger protein 150 | -0.0232176 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.023149 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0230467 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.022974 |
| RPL7A | ribosomal protein L7a | -0.0228921 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0228737 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0226821 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0226572 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0225307 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0224571 |
