| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (hydrochloride) perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Imiquimod (hydrochloride)_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.115121 |
| FLNA | filamin A, alpha | 0.0850202 |
| RPL3 | ribosomal protein L3 | 0.0801148 |
| POTEF | POTE ankyrin domain family, member F | 0.0784497 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0738075 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0722113 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0643261 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0643005 |
| PKM | pyruvate kinase, muscle | 0.0638947 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0607814 |
| RACK1 | receptor for activated C kinase 1 | 0.0516601 |
| NDRG1 | N-myc downstream regulated 1 | 0.0509836 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0495777 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0493833 |
| CCNL1 | cyclin L1 | 0.0484265 |
| FNBP1L | formin binding protein 1-like | 0.0482535 |
| PCBP2 | poly(rC) binding protein 2 | 0.0481976 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.046051 |
| B2M | beta-2-microglobulin | 0.0460042 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0455901 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0450543 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0446294 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0429456 |
| TPM4 | tropomyosin 4 | 0.0421915 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0418134 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0403188 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0396231 |
| RNF145 | ring finger protein 145 | 0.0380107 |
| HELZ | helicase with zinc finger | 0.0379668 |
| ZNF292 | zinc finger protein 292 | 0.0374276 |
| NUP58 | nucleoporin 58 | 0.037281 |
| NCKAP1 | NCK-associated protein 1 | 0.0362796 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0360412 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0358227 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0350056 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0345845 |
| LDHA | lactate dehydrogenase A | 0.0335484 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0329697 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0329655 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0328646 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0303395 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.030277 |
| DHFR | dihydrofolate reductase | 0.0299914 |
| ENO1 | enolase 1, (alpha) | 0.0299448 |
| SLMAP | sarcolemma associated protein | 0.028742 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0285889 |
| YBX1 | Y box binding protein 1 | 0.0281346 |
| SET | SET nuclear proto-oncogene | 0.0281335 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0277826 |
| PLEC | plectin | 0.0273431 |
| YTHDC1 | YTH domain containing 1 | 0.0272695 |
| UBC | ubiquitin C | 0.0269873 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0264542 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.026242 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.02603 |
| TPM3 | tropomyosin 3 | 0.0257881 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.025686 |
| SPOPL | speckle-type POZ protein-like | 0.0253331 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0249596 |
| INSIG2 | insulin induced gene 2 | 0.0249244 |
| TPI1 | triosephosphate isomerase 1 | 0.0249148 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0247202 |
| ANXA2 | annexin A2 | 0.0245416 |
| AXL | AXL receptor tyrosine kinase | 0.0245264 |
| SEPTIN9 | septin 9 | 0.0245148 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0244259 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0242922 |
| APP | amyloid beta (A4) precursor protein | 0.0241633 |
| TFG | TRK-fused gene | 0.0237813 |
| VEGFA | vascular endothelial growth factor A | 0.0237637 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0232671 |
| SETD5 | SET domain containing 5 | 0.0231916 |
| RPL4 | ribosomal protein L4 | 0.0231415 |
| HMGA1 | high mobility group AT-hook 1 | 0.0228448 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0224459 |
| CALR | calreticulin | 0.0222504 |
| RNASE3 | ribonuclease, RNase A family, 3 | 0.022093 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0218801 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0218024 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0217601 |
| DIAPH1 | diaphanous-related formin 1 | 0.021756 |
| TPD52 | tumor protein D52 | 0.0217544 |
| PER1 | period circadian clock 1 | 0.0215937 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0215746 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0214998 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0214676 |
| WASF2 | WAS protein family, member 2 | 0.02104 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0209976 |
| GOLGA4 | golgin A4 | 0.0208864 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | 0.0207259 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0206595 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.0206449 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0205993 |
| HDGF | hepatoma-derived growth factor | 0.0205911 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0205284 |
| RIOK3 | RIO kinase 3 | 0.0204208 |
| SMAD3 | SMAD family member 3 | 0.020218 |
| MATR3 | matrin 3 | 0.0201357 |
| HYOU1 | hypoxia up-regulated 1 | 0.0199808 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0199086 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.140752 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0990584 |
| ASPH | aspartate beta-hydroxylase | -0.0829071 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0574966 |
| PATJ | PATJ crumbs cell polarity complex component | -0.055158 |
| RPL35A | ribosomal protein L35a | -0.0529215 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0513367 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0508801 |
| TBC1D5 | TBC1 domain family, member 5 | -0.048445 |
| TXNRD1 | thioredoxin reductase 1 | -0.0481935 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0481426 |
| TMSB10 | thymosin beta 10 | -0.0450569 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0448363 |
| MACROD2 | MACRO domain containing 2 | -0.0443935 |
| WWOX | WW domain containing oxidoreductase | -0.0435454 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0432378 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0404546 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0399875 |
| RAD51B | RAD51 paralog B | -0.0382236 |
| CCND1 | cyclin D1 | -0.0380507 |
| SMYD3 | SET and MYND domain containing 3 | -0.0380185 |
| PRELID2 | PRELI domain containing 2 | -0.0378298 |
| RPLP1 | ribosomal protein, large, P1 | -0.0377255 |
| SVIL | supervillin | -0.0376618 |
| MAP4 | microtubule-associated protein 4 | -0.0361167 |
| RPL9 | ribosomal protein L9 | -0.03575 |
| ATG7 | autophagy related 7 | -0.0333802 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0333315 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0330146 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0328242 |
| HMGB1 | high mobility group box 1 | -0.0327563 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.031878 |
| DIAPH3 | diaphanous-related formin 3 | -0.0316112 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0306749 |
| RPL26 | ribosomal protein L26 | -0.0306447 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0304137 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0300031 |
| HMGA2 | high mobility group AT-hook 2 | -0.0299008 |
| RPLP2 | ribosomal protein, large, P2 | -0.0294474 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0293964 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0293758 |
| RPS8 | ribosomal protein S8 | -0.0292816 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0290361 |
| SUMF1 | sulfatase modifying factor 1 | -0.0288839 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0286849 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0285759 |
| TCF12 | transcription factor 12 | -0.0285584 |
| NF1 | neurofibromin 1 | -0.0285074 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0279805 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0278072 |
| RPL34 | ribosomal protein L34 | -0.0277873 |
| RPS24 | ribosomal protein S24 | -0.0275598 |
| RPL19 | ribosomal protein L19 | -0.0274938 |
| FHIT | fragile histidine triad | -0.0272532 |
| BPTF | bromodomain PHD finger transcription factor | -0.0271869 |
| EXOC4 | exocyst complex component 4 | -0.0270808 |
| S100A10 | S100 calcium binding protein A10 | -0.0270665 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0269466 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0268137 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0264247 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0262917 |
| PTMA | prothymosin, alpha | -0.0262914 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0259038 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0257737 |
| RPL38 | ribosomal protein L38 | -0.0257567 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0255189 |
| ITGB8 | integrin, beta 8 | -0.0252047 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0250745 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0249808 |
| RPL12 | ribosomal protein L12 | -0.0243884 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.02424 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0241474 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0239692 |
| EHBP1 | EH domain binding protein 1 | -0.0237309 |
| PCNX4 | pecanex 4 | -0.0236699 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.023664 |
| CD44 | CD44 molecule (Indian blood group) | -0.0235438 |
| RPS27A | ribosomal protein S27a | -0.0232177 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0229437 |
| BICC1 | BicC family RNA binding protein 1 | -0.022925 |
| PLCB4 | phospholipase C, beta 4 | -0.0228929 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0228572 |
| GPATCH8 | G patch domain containing 8 | -0.0227902 |
| RPS19 | ribosomal protein S19 | -0.0227443 |
| MTAP | methylthioadenosine phosphorylase | -0.0226354 |
| RPS21 | ribosomal protein S21 | -0.0226313 |
| FUS | FUS RNA binding protein | -0.0225021 |
| PTK2 | protein tyrosine kinase 2 | -0.0224621 |
| RPL31 | ribosomal protein L31 | -0.0221911 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.0221775 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0220679 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0220617 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0220493 |
| NDUFAF2 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 | -0.0220456 |
| CEP95 | centrosomal protein 95kDa | -0.0220276 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0220113 |
| BRCA2 | breast cancer 2, early onset | -0.0219255 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.0219106 |
| TMSB4X | thymosin beta 4, X-linked | -0.0216639 |
| RPL35 | ribosomal protein L35 | -0.0215907 |
