| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (hydrochloride) perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Imiquimod (hydrochloride)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.0659772 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0650321 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0514458 |
| PLEC | plectin | 0.0490118 |
| FLNA | filamin A, alpha | 0.0413045 |
| SMAD3 | SMAD family member 3 | 0.0385002 |
| MYOF | myoferlin | 0.0365155 |
| DHFR | dihydrofolate reductase | 0.0296654 |
| RPL3 | ribosomal protein L3 | 0.0280721 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0274647 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0249847 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.024386 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0242235 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0241746 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 0.0241495 |
| AHNAK | AHNAK nucleoprotein | 0.0241168 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0233638 |
| MSN | moesin | 0.0227217 |
| NAV2 | neuron navigator 2 | 0.0222837 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0221859 |
| VCL | vinculin | 0.0209209 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0201562 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0194795 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0188347 |
| MEF2A | myocyte enhancer factor 2A | 0.0187551 |
| MEGF6 | multiple EGF-like-domains 6 | 0.0186761 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0182344 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0180799 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0178086 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0177932 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0176686 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0176268 |
| KRT6A | keratin 6A, type II | 0.0173059 |
| LAMA5 | laminin, alpha 5 | 0.0170614 |
| ARRDC3 | arrestin domain containing 3 | 0.0168138 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0168093 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0165848 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0163571 |
| KIF16B | kinesin family member 16B | 0.015948 |
| MCL1 | myeloid cell leukemia 1 | 0.0157887 |
| KIAA1217 | KIAA1217 | 0.0157404 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0156084 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0154618 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0153163 |
| UBAP2L | ubiquitin associated protein 2-like | 0.015028 |
| RAI14 | retinoic acid induced 14 | 0.0145596 |
| TGM2 | transglutaminase 2 | 0.0145574 |
| LOXL2 | lysyl oxidase-like 2 | 0.0145286 |
| ANO6 | anoctamin 6 | 0.0141875 |
| EPHA2 | EPH receptor A2 | 0.013994 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0139891 |
| RBM39 | RNA binding motif protein 39 | 0.0139002 |
| CEP250 | centrosomal protein 250kDa | 0.0138828 |
| COG6 | component of oligomeric golgi complex 6 | 0.0136224 |
| SEPTIN9 | septin 9 | 0.0132794 |
| CAPRIN2 | caprin family member 2 | 0.0132088 |
| LMO7 | LIM domain 7 | 0.0129076 |
| SDHA | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 0.0127436 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0126883 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0126698 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0125837 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0125264 |
| SUCO | SUN domain containing ossification factor | 0.0125258 |
| RASA3 | RAS p21 protein activator 3 | 0.012278 |
| BLCAP | bladder cancer associated protein | 0.0122494 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0121594 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0119686 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0119348 |
| PMM2 | phosphomannomutase 2 | 0.0117811 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | 0.0116976 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0115941 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0114528 |
| COPA | coatomer protein complex, subunit alpha | 0.0114526 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0114281 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0114265 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0113855 |
| SLTM | SAFB-like, transcription modulator | 0.0112661 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0110292 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0109253 |
| CLIC4 | chloride intracellular channel 4 | 0.0108279 |
| TPM3 | tropomyosin 3 | 0.0108154 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0107508 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0106576 |
| EZR | ezrin | 0.0106172 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0105232 |
| FBXO42 | F-box protein 42 | 0.0105211 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0103645 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0103086 |
| ACTN1 | actinin, alpha 1 | 0.0102777 |
| FAM114A1 | family with sequence similarity 114, member A1 | 0.0102712 |
| RNF19B | ring finger protein 19B | 0.0102259 |
| PRELID2 | PRELI domain containing 2 | 0.0101945 |
| ARCN1 | archain 1 | 0.0101423 |
| INTS6 | integrator complex subunit 6 | 0.00994843 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0097919 |
| SERINC1 | serine incorporator 1 | 0.00976264 |
| SULF1 | sulfatase 1 | 0.00961548 |
| OSBPL2 | oxysterol binding protein-like 2 | 0.00957274 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.00947876 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.00943248 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.166757 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.146588 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.137513 |
| B2M | beta-2-microglobulin | -0.102603 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0967526 |
| MT2A | metallothionein 2A | -0.0957067 |
| TMSB10 | thymosin beta 10 | -0.088549 |
| RPS6 | ribosomal protein S6 | -0.0878574 |
| RPS21 | ribosomal protein S21 | -0.0806264 |
| PTMA | prothymosin, alpha | -0.0760318 |
| RPS8 | ribosomal protein S8 | -0.0737151 |
| S100A10 | S100 calcium binding protein A10 | -0.0725323 |
| RPLP1 | ribosomal protein, large, P1 | -0.0654781 |
| RPLP2 | ribosomal protein, large, P2 | -0.0608774 |
| HLA-B | major histocompatibility complex, class I, B | -0.0592673 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.058121 |
| CLU | clusterin | -0.0551519 |
| RPS19 | ribosomal protein S19 | -0.0527447 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0511367 |
| TMSB4X | thymosin beta 4, X-linked | -0.0501491 |
| RPS13 | ribosomal protein S13 | -0.047779 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0455158 |
| RPL11 | ribosomal protein L11 | -0.0449761 |
| RPL35A | ribosomal protein L35a | -0.0446478 |
| RPL12 | ribosomal protein L12 | -0.0434734 |
| RPS24 | ribosomal protein S24 | -0.0433227 |
| GNAS | GNAS complex locus | -0.0427389 |
| S100A6 | S100 calcium binding protein A6 | -0.0419174 |
| ENO1 | enolase 1, (alpha) | -0.041875 |
| FTL | ferritin, light polypeptide | -0.0412163 |
| RPS12 | ribosomal protein S12 | -0.0409249 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0402756 |
| RPL34 | ribosomal protein L34 | -0.0400764 |
| RPS3 | ribosomal protein S3 | -0.0391915 |
| RPS25 | ribosomal protein S25 | -0.0391707 |
| POTEF | POTE ankyrin domain family, member F | -0.0380363 |
| RPL37 | ribosomal protein L37 | -0.0377006 |
| RPL37A | ribosomal protein L37a | -0.0376118 |
| S100A9 | S100 calcium binding protein A9 | -0.0374548 |
| LDHA | lactate dehydrogenase A | -0.0372449 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0371727 |
| RPLP0 | ribosomal protein, large, P0 | -0.0355361 |
| RPS14 | ribosomal protein S14 | -0.0355159 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0350908 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0348779 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0340501 |
| RPL31 | ribosomal protein L31 | -0.0340283 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0339457 |
| S100A2 | S100 calcium binding protein A2 | -0.033746 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0336835 |
| RPL9 | ribosomal protein L9 | -0.0335392 |
| RPL26 | ribosomal protein L26 | -0.0330422 |
| RPL19 | ribosomal protein L19 | -0.0328703 |
| S100A11 | S100 calcium binding protein A11 | -0.0327447 |
| RPL23 | ribosomal protein L23 | -0.0322089 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0321899 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0317008 |
| RPL35 | ribosomal protein L35 | -0.0313927 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0309783 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0309757 |
| RPL32 | ribosomal protein L32 | -0.0308182 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.030587 |
| RPL36 | ribosomal protein L36 | -0.0305633 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0303805 |
| RPS23 | ribosomal protein S23 | -0.0296927 |
| RPS27A | ribosomal protein S27a | -0.029475 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0292203 |
| MT1X | metallothionein 1X | -0.0288319 |
| RPL27A | ribosomal protein L27a | -0.0284219 |
| PGK1 | phosphoglycerate kinase 1 | -0.0284063 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.028352 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.02811 |
| RPS27 | ribosomal protein S27 | -0.0278997 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0276539 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0270175 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0265598 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0261579 |
| RPL8 | ribosomal protein L8 | -0.0261266 |
| RPS29 | ribosomal protein S29 | -0.02599 |
| RPL30 | ribosomal protein L30 | -0.0259131 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0258139 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0258044 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0257683 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0255329 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0251653 |
| RPS17 | ribosomal protein S17 | -0.0248995 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0246309 |
| RPL5 | ribosomal protein L5 | -0.0243131 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0242496 |
| RPS11 | ribosomal protein S11 | -0.0240216 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0239134 |
| PFN1 | profilin 1 | -0.0238363 |
| PRRC2C | proline-rich coiled-coil 2C | -0.023761 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0237254 |
| RPL7A | ribosomal protein L7a | -0.0235069 |
| ACTG1 | actin gamma 1 | -0.0231656 |
| RPL36A | ribosomal protein L36a | -0.023101 |
| STC1 | stanniocalcin 1 | -0.0229128 |
| RPL28 | ribosomal protein L28 | -0.0226806 |
| RPS16 | ribosomal protein S16 | -0.022607 |
