| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (hydrochloride) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Imiquimod (hydrochloride)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0565086 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0544799 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.042505 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0409723 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0407407 |
| FLNA | filamin A, alpha | 0.0359073 |
| ATP13A3 | ATPase type 13A3 | 0.0341096 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0333686 |
| ZNF841 | zinc finger protein 841 | 0.0321806 |
| NAV2 | neuron navigator 2 | 0.0294887 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0288731 |
| CALR | calreticulin | 0.0274597 |
| AHNAK | AHNAK nucleoprotein | 0.0270817 |
| UBC | ubiquitin C | 0.0256354 |
| COL5A1 | collagen, type V, alpha 1 | 0.0254167 |
| FLNB | filamin B, beta | 0.0251774 |
| SLC12A8 | solute carrier family 12, member 8 | 0.023992 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0235195 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0230587 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0226169 |
| NUP58 | nucleoporin 58 | 0.0222447 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0219497 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0216383 |
| MCL1 | myeloid cell leukemia 1 | 0.0213395 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0205067 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0201644 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0199174 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0190662 |
| TPM3 | tropomyosin 3 | 0.0190244 |
| SMAD3 | SMAD family member 3 | 0.0190235 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0189354 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0185914 |
| NUP153 | nucleoporin 153kDa | 0.0185738 |
| ARF4 | ADP-ribosylation factor 4 | 0.0185481 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0175003 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0174993 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.017498 |
| LOX | lysyl oxidase | 0.0173436 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0173085 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.017244 |
| PLEC | plectin | 0.0171712 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0169104 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0168972 |
| UBAP2L | ubiquitin associated protein 2-like | 0.016871 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0167671 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0167216 |
| CORO1C | coronin, actin binding protein, 1C | 0.0162886 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0160911 |
| CALU | calumenin | 0.0157362 |
| ADM | adrenomedullin | 0.0156585 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0156252 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0153393 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0153023 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0150576 |
| FOXO3 | forkhead box O3 | 0.0150028 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0149498 |
| SEPTIN9 | septin 9 | 0.0148674 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0146278 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.014575 |
| FAM219A | family with sequence similarity 219, member A | 0.0145542 |
| HLA-C | major histocompatibility complex, class I, C | 0.0145245 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0145139 |
| JUN | jun proto-oncogene | 0.0143752 |
| SUCO | SUN domain containing ossification factor | 0.0143724 |
| GPR107 | G protein-coupled receptor 107 | 0.0143314 |
| SRP54 | signal recognition particle 54kDa | 0.0143171 |
| RAB18 | RAB18, member RAS oncogene family | 0.0139896 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0138265 |
| GOLGA2 | golgin A2 | 0.0137721 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0137369 |
| NDRG1 | N-myc downstream regulated 1 | 0.0136869 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0136628 |
| CANX | calnexin | 0.0136196 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0135965 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0135167 |
| HLA-E | major histocompatibility complex, class I, E | 0.0133683 |
| ECT2 | epithelial cell transforming 2 | 0.013335 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0133048 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0130944 |
| RBM39 | RNA binding motif protein 39 | 0.0129157 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0127756 |
| ARRDC3 | arrestin domain containing 3 | 0.0127677 |
| MSN | moesin | 0.0127571 |
| CLIC4 | chloride intracellular channel 4 | 0.0126919 |
| TMF1 | TATA element modulatory factor 1 | 0.0126906 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0126473 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0124793 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0124604 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0123112 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0122913 |
| VMP1 | vacuole membrane protein 1 | 0.0122758 |
| TLN1 | talin 1 | 0.0121857 |
| PLK2 | polo-like kinase 2 | 0.0121378 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.0119686 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0119387 |
| PFKP | phosphofructokinase, platelet | 0.0118739 |
| TMEM41B | transmembrane protein 41B | 0.0118681 |
| STC2 | stanniocalcin 2 | 0.0116094 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0114908 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0114881 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.0910315 |
| HLA-B | major histocompatibility complex, class I, B | -0.0826838 |
| FTL | ferritin, light polypeptide | -0.0690185 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0551728 |
| RPS6 | ribosomal protein S6 | -0.0390146 |
| TMSB10 | thymosin beta 10 | -0.0378889 |
| RPL35A | ribosomal protein L35a | -0.0335276 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0301988 |
| VIM | vimentin | -0.0299931 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0293781 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0288525 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0285554 |
| PTMA | prothymosin, alpha | -0.025751 |
| RPL12 | ribosomal protein L12 | -0.0252443 |
| FN1 | fibronectin 1 | -0.0251815 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.023256 |
| RPS19 | ribosomal protein S19 | -0.0214198 |
| PFN1 | profilin 1 | -0.0214025 |
| RPL26 | ribosomal protein L26 | -0.0212273 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0210627 |
| RPLP1 | ribosomal protein, large, P1 | -0.0208001 |
| RPLP2 | ribosomal protein, large, P2 | -0.0206451 |
| HMGB1 | high mobility group box 1 | -0.0205271 |
| ACTG1 | actin gamma 1 | -0.0204902 |
| ASPH | aspartate beta-hydroxylase | -0.0195977 |
| RPL37A | ribosomal protein L37a | -0.0193884 |
| RPL35 | ribosomal protein L35 | -0.0193691 |
| RPL23 | ribosomal protein L23 | -0.0190961 |
| RPS3 | ribosomal protein S3 | -0.0188159 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0185167 |
| S100A6 | S100 calcium binding protein A6 | -0.0184195 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0174749 |
| RPS12 | ribosomal protein S12 | -0.015871 |
| ZNF804A | zinc finger protein 804A | -0.0158603 |
| RPS8 | ribosomal protein S8 | -0.0150182 |
| DIAPH3 | diaphanous-related formin 3 | -0.0148748 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.014778 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0146607 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0145168 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0143221 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0142987 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0141952 |
| ANXA2 | annexin A2 | -0.0140976 |
| RPL34 | ribosomal protein L34 | -0.0140284 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0140152 |
| RPL31 | ribosomal protein L31 | -0.013737 |
| RPL19 | ribosomal protein L19 | -0.0136902 |
| RPS17 | ribosomal protein S17 | -0.0136507 |
| RPL37 | ribosomal protein L37 | -0.0134917 |
| RPS13 | ribosomal protein S13 | -0.013472 |
| GNAS | GNAS complex locus | -0.0133985 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0133834 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0131514 |
| B2M | beta-2-microglobulin | -0.0131223 |
| POMP | proteasome maturation protein | -0.0127886 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0127293 |
| S100A11 | S100 calcium binding protein A11 | -0.0126324 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0123123 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0122942 |
| RPL9 | ribosomal protein L9 | -0.0122189 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0120929 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0119958 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | -0.0119248 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0118781 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0117565 |
| TCF12 | transcription factor 12 | -0.0117555 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0117479 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0117203 |
| PLSCR1 | phospholipid scramblase 1 | -0.0116559 |
| SMYD3 | SET and MYND domain containing 3 | -0.0116472 |
| RPL5 | ribosomal protein L5 | -0.0114525 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0114234 |
| RPS14 | ribosomal protein S14 | -0.0113478 |
| PLCB4 | phospholipase C, beta 4 | -0.0110832 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0110778 |
| CCBE1 | collagen and calcium binding EGF domains 1 | -0.0106762 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0105899 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0104717 |
| POTEF | POTE ankyrin domain family, member F | -0.0104262 |
| ZNF432 | zinc finger protein 432 | -0.0100729 |
| RIGI | RNA sensor RIG-I | -0.0100464 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.010039 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00994947 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.00993862 |
| RPL36 | ribosomal protein L36 | -0.00992025 |
| SEC61G | Sec61 gamma subunit | -0.00991497 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.00987183 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.00983543 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.00979681 |
| HMGA1 | high mobility group AT-hook 1 | -0.00968288 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.00962941 |
| RPL30 | ribosomal protein L30 | -0.00960419 |
| S100A9 | S100 calcium binding protein A9 | -0.00956222 |
| RPS10 | ribosomal protein S10 | -0.0095565 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.00939854 |
| RAD51B | RAD51 paralog B | -0.00927763 |
| OSMR | oncostatin M receptor | -0.00927528 |
| RPL11 | ribosomal protein L11 | -0.00923543 |
| GLIS3 | GLIS family zinc finger 3 | -0.00920286 |
| RPL28 | ribosomal protein L28 | -0.00910303 |
