| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (hydrochloride) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Imiquimod (hydrochloride)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.153154 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0930873 |
| RACK1 | receptor for activated C kinase 1 | 0.0904124 |
| RPL3 | ribosomal protein L3 | 0.083883 |
| POTEF | POTE ankyrin domain family, member F | 0.0540472 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.048431 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0470224 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0430486 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0429038 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0421373 |
| RPL23 | ribosomal protein L23 | 0.0410758 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.040992 |
| RAI1 | retinoic acid induced 1 | 0.0395532 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0380174 |
| MKI67 | marker of proliferation Ki-67 | 0.0377521 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0376223 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0369005 |
| TMSB4X | thymosin beta 4, X-linked | 0.0367634 |
| RPL4 | ribosomal protein L4 | 0.0343487 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.034278 |
| ARRDC3 | arrestin domain containing 3 | 0.0339619 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0338256 |
| TPM3 | tropomyosin 3 | 0.0336322 |
| PLK2 | polo-like kinase 2 | 0.0318855 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0315736 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0312173 |
| HMGA1 | high mobility group AT-hook 1 | 0.0309863 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0299694 |
| SZRD1 | SUZ RNA binding domain containing 1 | 0.0297134 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0295995 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0294211 |
| YBX1 | Y box binding protein 1 | 0.0294003 |
| MCL1 | myeloid cell leukemia 1 | 0.0289846 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0289308 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0287347 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0287213 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0283777 |
| RPL11 | ribosomal protein L11 | 0.028355 |
| UBC | ubiquitin C | 0.0280815 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0261755 |
| RPL37 | ribosomal protein L37 | 0.0256969 |
| NUP58 | nucleoporin 58 | 0.0255146 |
| CENPF | centromere protein F, 350/400kDa | 0.0252312 |
| PKM | pyruvate kinase, muscle | 0.0247272 |
| NCKAP1 | NCK-associated protein 1 | 0.0237759 |
| SET | SET nuclear proto-oncogene | 0.0227931 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0226948 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0224177 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0222586 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0222054 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0217274 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0215079 |
| RNF145 | ring finger protein 145 | 0.0214997 |
| RPL21 | ribosomal protein L21 | 0.0214147 |
| F2R | coagulation factor II (thrombin) receptor | 0.0213953 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0213205 |
| TPI1 | triosephosphate isomerase 1 | 0.0211616 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0207216 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0206644 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0205222 |
| RPS3 | ribosomal protein S3 | 0.0204484 |
| PCBP2 | poly(rC) binding protein 2 | 0.0200948 |
| PNN | pinin, desmosome associated protein | 0.0199951 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 0.0197975 |
| PLEC | plectin | 0.0196565 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0195941 |
| XPO1 | exportin 1 | 0.0195083 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0194786 |
| SLK | STE20-like kinase | 0.0194455 |
| HMGB2 | high mobility group box 2 | 0.0191742 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0190824 |
| HDGF | hepatoma-derived growth factor | 0.0190459 |
| RPS12 | ribosomal protein S12 | 0.0190266 |
| DOCK11 | dedicator of cytokinesis 11 | 0.0189615 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0186212 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0184527 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0183084 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0182595 |
| HLA-A | major histocompatibility complex, class I, A | 0.0182587 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0179709 |
| RPL8 | ribosomal protein L8 | 0.0178804 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0176149 |
| HSPA4 | heat shock 70kDa protein 4 | 0.0175135 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0174247 |
| PYGL | phosphorylase, glycogen, liver | 0.0173455 |
| MSN | moesin | 0.0170662 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0169145 |
| BEGAIN | brain-enriched guanylate kinase-associated | 0.0166132 |
| KLC1 | kinesin light chain 1 | 0.0164334 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0163904 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.016388 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0163564 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0161138 |
| CASC3 | cancer susceptibility candidate 3 | 0.01608 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0160069 |
| TAPBP | TAP binding protein (tapasin) | 0.0158237 |
| WDR43 | WD repeat domain 43 | 0.0158011 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0157842 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.015747 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0156492 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.219141 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.129775 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.121915 |
| VIM | vimentin | -0.100446 |
| CD44 | CD44 molecule (Indian blood group) | -0.097095 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0829557 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0817058 |
| TP63 | tumor protein p63 | -0.080307 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0739768 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0669166 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0650941 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0646014 |
| RUNX1 | runt-related transcription factor 1 | -0.0640703 |
| ACTG1 | actin gamma 1 | -0.0591211 |
| EHBP1 | EH domain binding protein 1 | -0.0589728 |
| DST | dystonin | -0.0576579 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0575608 |
| TMSB10 | thymosin beta 10 | -0.0567861 |
| RIGI | RNA sensor RIG-I | -0.0567247 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0544018 |
| SP100 | SP100 nuclear antigen | -0.048789 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0475262 |
| JMJD1C | jumonji domain containing 1C | -0.0462571 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0449049 |
| SPAG9 | sperm associated antigen 9 | -0.0444616 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0440305 |
| HLA-B | major histocompatibility complex, class I, B | -0.043396 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0423288 |
| FBXO11 | F-box protein 11 | -0.040699 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0403003 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0384515 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0379568 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0378137 |
| BPTF | bromodomain PHD finger transcription factor | -0.0368794 |
| CANX | calnexin | -0.0367299 |
| HDAC9 | histone deacetylase 9 | -0.0366257 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0365286 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0364556 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0356175 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0355303 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0349282 |
| PLSCR1 | phospholipid scramblase 1 | -0.0343403 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0342709 |
| TXNRD1 | thioredoxin reductase 1 | -0.0342277 |
| MT1E | metallothionein 1E | -0.0340859 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0340007 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0337387 |
| CFAP299 | cilia and flagella associated protein 299 | -0.033182 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0327382 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0324321 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0323469 |
| USP34 | ubiquitin specific peptidase 34 | -0.0322779 |
| RPLP1 | ribosomal protein, large, P1 | -0.0314956 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0314882 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0314786 |
| NF1 | neurofibromin 1 | -0.031395 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0313716 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0311866 |
| MT2A | metallothionein 2A | -0.0309464 |
| PMP22 | peripheral myelin protein 22 | -0.0306962 |
| EXOC4 | exocyst complex component 4 | -0.0305705 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0303411 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0300044 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0298016 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.029737 |
| SDC4 | syndecan 4 | -0.0297094 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0295309 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0295205 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0292899 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0290814 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0289303 |
| ANXA2 | annexin A2 | -0.0287733 |
| MT1X | metallothionein 1X | -0.0287715 |
| JUN | jun proto-oncogene | -0.0285198 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0279268 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0274919 |
| CADM2 | cell adhesion molecule 2 | -0.027427 |
| CDK13 | cyclin-dependent kinase 13 | -0.0274164 |
| EMP1 | epithelial membrane protein 1 | -0.0272124 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0271647 |
| ANXA1 | annexin A1 | -0.0270869 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0269763 |
| CMIP | c-Maf inducing protein | -0.0267068 |
| GLG1 | golgi glycoprotein 1 | -0.0265537 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0265169 |
| GOLGB1 | golgin B1 | -0.0260959 |
| RAD51B | RAD51 paralog B | -0.0256999 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0256569 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0254189 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0251784 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0251079 |
| TRIM56 | tripartite motif containing 56 | -0.0251037 |
| RPL38 | ribosomal protein L38 | -0.0250355 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0248946 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0248267 |
| SMYD3 | SET and MYND domain containing 3 | -0.0246642 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.024387 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0242568 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0239746 |
| FMNL2 | formin-like 2 | -0.0239646 |
