| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (hydrochloride) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Imiquimod (hydrochloride)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0637285 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0597976 |
| SMAD3 | SMAD family member 3 | 0.0581923 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0541521 |
| ARRDC3 | arrestin domain containing 3 | 0.0540187 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0533195 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0529531 |
| NAV2 | neuron navigator 2 | 0.052826 |
| RACK1 | receptor for activated C kinase 1 | 0.0519731 |
| KRT17 | keratin 17, type I | 0.0508927 |
| CALR | calreticulin | 0.0495494 |
| MUC4 | mucin 4, cell surface associated | 0.0493089 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0470835 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0455121 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0445959 |
| PTMA | prothymosin, alpha | 0.0443904 |
| C3 | complement component 3 | 0.0419178 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0406284 |
| TGM2 | transglutaminase 2 | 0.0401113 |
| KRT18 | keratin 18, type I | 0.0384236 |
| G0S2 | G0/G1 switch 2 | 0.0378829 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0371307 |
| RPL23 | ribosomal protein L23 | 0.036753 |
| MKI67 | marker of proliferation Ki-67 | 0.0366257 |
| FAM3C | family with sequence similarity 3, member C | 0.0353858 |
| OGA | O-GlcNAcase | 0.0343882 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0340022 |
| HLA-B | major histocompatibility complex, class I, B | 0.0326687 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0320483 |
| UBC | ubiquitin C | 0.0318577 |
| FLNA | filamin A, alpha | 0.0316156 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0313351 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0307333 |
| AFDN | afadin, adherens junction formation factor | 0.0301986 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0300646 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0291733 |
| RPL3 | ribosomal protein L3 | 0.0288129 |
| KRT7 | keratin 7, type II | 0.0285585 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0285076 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0276348 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0275073 |
| RIOK3 | RIO kinase 3 | 0.0272804 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0268756 |
| NCKAP1 | NCK-associated protein 1 | 0.0268037 |
| ATP13A3 | ATPase type 13A3 | 0.02622 |
| STK24 | serine/threonine kinase 24 | 0.0259801 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0258044 |
| VEGFA | vascular endothelial growth factor A | 0.0257945 |
| BRD4 | bromodomain containing 4 | 0.0257911 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0254468 |
| CUL3 | cullin 3 | 0.0252625 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0251989 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0248861 |
| PLEC | plectin | 0.0246422 |
| PCBP2 | poly(rC) binding protein 2 | 0.0244574 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0244465 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0243201 |
| FMNL2 | formin-like 2 | 0.0242079 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0235862 |
| HLA-A | major histocompatibility complex, class I, A | 0.0234738 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0233551 |
| FLNB | filamin B, beta | 0.0232998 |
| ACTN4 | actinin, alpha 4 | 0.0232471 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0232179 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.023065 |
| RPL4 | ribosomal protein L4 | 0.0229617 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0225498 |
| KLC1 | kinesin light chain 1 | 0.0225449 |
| SLMAP | sarcolemma associated protein | 0.0224217 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0224028 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0221606 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0220036 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0218156 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.021788 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0217873 |
| TPM4 | tropomyosin 4 | 0.0216009 |
| LAMC2 | laminin, gamma 2 | 0.021532 |
| MYO5B | myosin VB | 0.0214486 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.02143 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0213728 |
| ANXA11 | annexin A11 | 0.0210761 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0209409 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0209319 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0208712 |
| AHNAK | AHNAK nucleoprotein | 0.0207511 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0207034 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0206632 |
| TPM3 | tropomyosin 3 | 0.0204973 |
| CASC3 | cancer susceptibility candidate 3 | 0.0204946 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.02043 |
| TPI1 | triosephosphate isomerase 1 | 0.0203139 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0199621 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0198057 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0197893 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0197 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0196582 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0193928 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0193814 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.01918 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0191028 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.0818841 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0596664 |
| EMP1 | epithelial membrane protein 1 | -0.0587721 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0581173 |
| ANXA2 | annexin A2 | -0.0553325 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0533222 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0527549 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0504181 |
| EZR | ezrin | -0.0454761 |
| ASPH | aspartate beta-hydroxylase | -0.0423594 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0421832 |
| LAMA4 | laminin, alpha 4 | -0.0415204 |
| GOLGB1 | golgin B1 | -0.0404692 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0377816 |
| CD2AP | CD2-associated protein | -0.0373337 |
| ANXA1 | annexin A1 | -0.0349674 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0349442 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0348576 |
| RASAL2 | RAS protein activator like 2 | -0.0344722 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0329907 |
| EHBP1 | EH domain binding protein 1 | -0.0317876 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0314056 |
| DSG2 | desmoglein 2 | -0.0310121 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0303727 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0298612 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0297059 |
| RAD51B | RAD51 paralog B | -0.0293394 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0287266 |
| SGMS2 | sphingomyelin synthase 2 | -0.0284302 |
| PLSCR1 | phospholipid scramblase 1 | -0.0277191 |
| EGR1 | early growth response 1 | -0.0269645 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0267889 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0267277 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0266636 |
| MT2A | metallothionein 2A | -0.0256326 |
| BPTF | bromodomain PHD finger transcription factor | -0.0252015 |
| MYO1E | myosin IE | -0.0247859 |
| ATF3 | activating transcription factor 3 | -0.0242676 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0239359 |
| MEF2A | myocyte enhancer factor 2A | -0.0236714 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0230916 |
| MX1 | MX dynamin-like GTPase 1 | -0.0228845 |
| MORF4L2 | mortality factor 4 like 2 | -0.022826 |
| TXNRD1 | thioredoxin reductase 1 | -0.0227195 |
| JMJD1C | jumonji domain containing 1C | -0.0226802 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0225999 |
| S100A6 | S100 calcium binding protein A6 | -0.0225145 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0224795 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0223218 |
| FBXO11 | F-box protein 11 | -0.0221555 |
| INTS6 | integrator complex subunit 6 | -0.0216886 |
| NF1 | neurofibromin 1 | -0.0216773 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0215809 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0214684 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0213721 |
| ACTG1 | actin gamma 1 | -0.0213687 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0213681 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0211779 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0209764 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0208007 |
| EFNA5 | ephrin-A5 | -0.0205366 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0200025 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0198565 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0196323 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0194838 |
| MX2 | MX dynamin-like GTPase 2 | -0.019188 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0191669 |
| TJP1 | tight junction protein 1 | -0.0191198 |
| YBX3 | Y box binding protein 3 | -0.0190788 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.0189424 |
| HMGA2 | high mobility group AT-hook 2 | -0.0189206 |
| GNAS | GNAS complex locus | -0.0187555 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0187269 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0186595 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0186325 |
| MYOF | myoferlin | -0.0185731 |
| PHF3 | PHD finger protein 3 | -0.0176476 |
| EGFR | epidermal growth factor receptor | -0.0173754 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0173196 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0173099 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit | -0.0172425 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.017226 |
| RIGI | RNA sensor RIG-I | -0.0172066 |
| TMEM87A | transmembrane protein 87A | -0.0171302 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0170665 |
| CBX3 | chromobox homolog 3 | -0.0167798 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.016743 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0167251 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0166363 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0166239 |
| MYADM | myeloid-associated differentiation marker | -0.016546 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0165312 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.016423 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0163988 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0163387 |
| TMSB10 | thymosin beta 10 | -0.0163178 |
| NRP1 | neuropilin 1 | -0.0162933 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0161615 |
| HDAC9 | histone deacetylase 9 | -0.0160972 |
| HMGB1 | high mobility group box 1 | -0.0159637 |
