| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (hydrochloride) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Imiquimod (hydrochloride)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.24368 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.079383 |
| STC1 | stanniocalcin 1 | 0.0664908 |
| FAM20C | family with sequence similarity 20, member C | 0.0592301 |
| PGK1 | phosphoglycerate kinase 1 | 0.0507219 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0506587 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0488913 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0434719 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0433651 |
| MSN | moesin | 0.0389245 |
| ATP13A3 | ATPase type 13A3 | 0.0378522 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0372766 |
| FLNA | filamin A, alpha | 0.0371999 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.035673 |
| TGM2 | transglutaminase 2 | 0.0346015 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0338785 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0331386 |
| NAV2 | neuron navigator 2 | 0.0329073 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0323513 |
| CD109 | CD109 molecule | 0.0318697 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0301344 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0300377 |
| NDRG1 | N-myc downstream regulated 1 | 0.0295656 |
| TFG | TRK-fused gene | 0.0293557 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0293367 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0290022 |
| PKM | pyruvate kinase, muscle | 0.0286048 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0282778 |
| ARRDC3 | arrestin domain containing 3 | 0.028 |
| COPA | coatomer protein complex, subunit alpha | 0.0269227 |
| ICAM1 | intercellular adhesion molecule 1 | 0.026671 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0266168 |
| NUP58 | nucleoporin 58 | 0.0259988 |
| PLEC | plectin | 0.0259493 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0257691 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0254752 |
| COL5A1 | collagen, type V, alpha 1 | 0.0253122 |
| LOXL2 | lysyl oxidase-like 2 | 0.0250956 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0250345 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0244537 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0242091 |
| INSIG2 | insulin induced gene 2 | 0.0241376 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0241159 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.02389 |
| ZNF292 | zinc finger protein 292 | 0.0237017 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0233006 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0232981 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0229701 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0229645 |
| PFKP | phosphofructokinase, platelet | 0.0227975 |
| CALU | calumenin | 0.0226046 |
| TPM3 | tropomyosin 3 | 0.0220613 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0218874 |
| HELZ | helicase with zinc finger | 0.0218265 |
| SMAD3 | SMAD family member 3 | 0.0215055 |
| TMEM39A | transmembrane protein 39A | 0.0214117 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0213784 |
| COL6A1 | collagen, type VI, alpha 1 | 0.021335 |
| MYO1B | myosin IB | 0.0213126 |
| CORO1C | coronin, actin binding protein, 1C | 0.0212862 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0210117 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0207041 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0204571 |
| AHNAK | AHNAK nucleoprotein | 0.0204103 |
| LDHA | lactate dehydrogenase A | 0.0201795 |
| FLNB | filamin B, beta | 0.0201791 |
| SETD5 | SET domain containing 5 | 0.0200504 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.020049 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0196707 |
| CEP70 | centrosomal protein 70kDa | 0.019555 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0194071 |
| POTEF | POTE ankyrin domain family, member F | 0.0192485 |
| PCBP2 | poly(rC) binding protein 2 | 0.019171 |
| VEGFA | vascular endothelial growth factor A | 0.0187473 |
| NCKAP1 | NCK-associated protein 1 | 0.0185332 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0184388 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0183073 |
| CENPF | centromere protein F, 350/400kDa | 0.018265 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0182578 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0182218 |
| MCL1 | myeloid cell leukemia 1 | 0.0181184 |
| CLDND1 | claudin domain containing 1 | 0.01807 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0180658 |
| ECT2 | epithelial cell transforming 2 | 0.0177713 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0177704 |
| XPO1 | exportin 1 | 0.0177171 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0176963 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0176704 |
| YEATS2 | YEATS domain containing 2 | 0.0175409 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0175331 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0175228 |
| AFAP1 | actin filament associated protein 1 | 0.0174887 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0174865 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.017402 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0172503 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.017128 |
| PGM3 | phosphoglucomutase 3 | 0.0171277 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0171252 |
| ACTN4 | actinin, alpha 4 | 0.0170716 |
| SERINC1 | serine incorporator 1 | 0.0170117 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.222687 |
| MT2A | metallothionein 2A | -0.126942 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.112553 |
| FTL | ferritin, light polypeptide | -0.103472 |
| TMSB10 | thymosin beta 10 | -0.0919545 |
| HLA-B | major histocompatibility complex, class I, B | -0.0874017 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0832293 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0821475 |
| PTMA | prothymosin, alpha | -0.0696771 |
| RPL35A | ribosomal protein L35a | -0.0631803 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0624479 |
| RPS6 | ribosomal protein S6 | -0.0610939 |
| COL1A2 | collagen, type I, alpha 2 | -0.0579152 |
| COL1A1 | collagen, type I, alpha 1 | -0.0576081 |
| RPLP1 | ribosomal protein, large, P1 | -0.0517665 |
| RPS8 | ribosomal protein S8 | -0.0517048 |
| B2M | beta-2-microglobulin | -0.0496954 |
| IER3 | immediate early response 3 | -0.0463579 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0457674 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0456441 |
| CDH13 | cadherin 13 | -0.0430292 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0423165 |
| RPL34 | ribosomal protein L34 | -0.0364589 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.035384 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0348981 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0342286 |
| SP100 | SP100 nuclear antigen | -0.0341954 |
| RPL12 | ribosomal protein L12 | -0.0338738 |
| RPL31 | ribosomal protein L31 | -0.0335975 |
| RPS19 | ribosomal protein S19 | -0.0334502 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0331249 |
| RPL37A | ribosomal protein L37a | -0.0326962 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0320035 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0313642 |
| ACTG1 | actin gamma 1 | -0.0310685 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0307638 |
| NAV1 | neuron navigator 1 | -0.0294855 |
| S100A6 | S100 calcium binding protein A6 | -0.0293273 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0287096 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0280538 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0279082 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0277063 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0275634 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0274866 |
| RPLP2 | ribosomal protein, large, P2 | -0.0270315 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0258507 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0254929 |
| RPS17 | ribosomal protein S17 | -0.0254229 |
| S100A9 | S100 calcium binding protein A9 | -0.0253096 |
| RPL32 | ribosomal protein L32 | -0.0252521 |
| IL1B | interleukin 1, beta | -0.0252451 |
| RPS24 | ribosomal protein S24 | -0.0252111 |
| S100A10 | S100 calcium binding protein A10 | -0.024631 |
| GLIS3 | GLIS family zinc finger 3 | -0.0244233 |
| FRMD4A | FERM domain containing 4A | -0.0243164 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0240847 |
| RPS21 | ribosomal protein S21 | -0.023986 |
| RPL9 | ribosomal protein L9 | -0.0234176 |
| GNAS | GNAS complex locus | -0.0230393 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0230275 |
| EGR1 | early growth response 1 | -0.0229247 |
| RPL28 | ribosomal protein L28 | -0.0228723 |
| HMGB1 | high mobility group box 1 | -0.022857 |
| NRP1 | neuropilin 1 | -0.0225321 |
| RPS3 | ribosomal protein S3 | -0.0222612 |
| FHIT | fragile histidine triad | -0.0222314 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.022115 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0220038 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0218217 |
| RPL19 | ribosomal protein L19 | -0.0217814 |
| TMEM178B | transmembrane protein 178B | -0.0217811 |
| RPL26 | ribosomal protein L26 | -0.0215543 |
| RPS5 | ribosomal protein S5 | -0.0207181 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0204337 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.020429 |
| RPL23 | ribosomal protein L23 | -0.0203233 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0193679 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0193482 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0193013 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0190981 |
| SQSTM1 | sequestosome 1 | -0.0189995 |
| RPS29 | ribosomal protein S29 | -0.01881 |
| RPLP0 | ribosomal protein, large, P0 | -0.0187265 |
| RPL27A | ribosomal protein L27a | -0.0187138 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0186623 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0183882 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.018354 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0183172 |
| SMYD3 | SET and MYND domain containing 3 | -0.0181049 |
| RPS11 | ribosomal protein S11 | -0.0180534 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0180442 |
| SELENOK | selenoprotein K | -0.0178833 |
| RPS27 | ribosomal protein S27 | -0.017825 |
| IFI44L | interferon-induced protein 44-like | -0.0177731 |
| RPL37 | ribosomal protein L37 | -0.0177702 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0174961 |
| RPL36 | ribosomal protein L36 | -0.0174722 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0173261 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0172706 |
| NREP | neuronal regeneration related protein | -0.0171253 |
