| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (hydrochloride) perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Imiquimod (hydrochloride)_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SMOC1 | SPARC related modular calcium binding 1 | 0.0601965 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0406263 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | 0.0366336 |
| RIT2 | Ras-like without CAAX 2 | 0.0303978 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0237368 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0230913 |
| DHFR | dihydrofolate reductase | 0.0223224 |
| RPL3 | ribosomal protein L3 | 0.0209567 |
| COL22A1 | collagen, type XXII, alpha 1 | 0.0208003 |
| ESRRG | estrogen-related receptor gamma | 0.0203269 |
| HDAC9 | histone deacetylase 9 | 0.0202956 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | 0.0198693 |
| PITPNM2 | phosphatidylinositol transfer protein, membrane-associated 2 | 0.0197712 |
| FGF14 | fibroblast growth factor 14 | 0.0191329 |
| CD24 | CD24 molecule | 0.0188392 |
| SIK2 | salt-inducible kinase 2 | 0.0183696 |
| DNAH5 | dynein, axonemal, heavy chain 5 | 0.0179711 |
| SASH1 | SAM and SH3 domain containing 1 | 0.0175096 |
| UBE2QL1 | ubiquitin-conjugating enzyme E2Q family-like 1 | 0.0165178 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0160873 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | 0.0153445 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 | 0.0151713 |
| NAV2 | neuron navigator 2 | 0.0149019 |
| AGMO | alkylglycerol monooxygenase | 0.0148757 |
| CNKSR3 | CNKSR family member 3 | 0.0148736 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0138261 |
| TOX | thymocyte selection-associated high mobility group box | 0.0132339 |
| SPTB | spectrin, beta, erythrocytic | 0.0131821 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0129593 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.012923 |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 | 0.0128889 |
| SERGEF | secretion regulating guanine nucleotide exchange factor | 0.0127595 |
| PRKD1 | protein kinase D1 | 0.0126777 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0125826 |
| SLC35F4 | solute carrier family 35, member F4 | 0.0124923 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0123734 |
| KCNJ6 | potassium channel, inwardly rectifying subfamily J, member 6 | 0.0121434 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0120635 |
| DACH1 | dachshund family transcription factor 1 | 0.0120492 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0119899 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0119458 |
| BAALC | brain and acute leukemia, cytoplasmic | 0.0114936 |
| PTCHD4 | patched domain containing 4 | 0.011456 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0111868 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | 0.0111053 |
| ST18 | suppression of tumorigenicity 18, zinc finger | 0.0110334 |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.0110158 |
| VAV2 | vav 2 guanine nucleotide exchange factor | 0.0110101 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.0109734 |
| LRFN2 | leucine rich repeat and fibronectin type III domain containing 2 | 0.0109115 |
| SCUBE1 | signal peptide, CUB domain, EGF-like 1 | 0.0108461 |
| SOBP | sine oculis binding protein homolog (Drosophila) | 0.0108199 |
| RPL4 | ribosomal protein L4 | 0.010662 |
| PAPOLA | poly(A) polymerase alpha | 0.0103838 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.0103822 |
| KCNB2 | potassium channel, voltage gated Shab related subfamily B, member 2 | 0.0103382 |
| BCL2 | B-cell CLL/lymphoma 2 | 0.0102747 |
| CELF4 | CUGBP, Elav-like family member 4 | 0.0100266 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 0.0098745 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.00986677 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.00983825 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | 0.0097593 |
| OXCT1 | 3-oxoacid CoA transferase 1 | 0.00966502 |
| LIN7A | lin-7 homolog A (C. elegans) | 0.00965906 |
| FHIT | fragile histidine triad | 0.00950375 |
| SNCAIP | synuclein, alpha interacting protein | 0.00941985 |
| PAEP | progestagen-associated endometrial protein | 0.00941132 |
| SEC23B | Sec23 homolog B (S. cerevisiae) | 0.00940483 |
| SYT13 | synaptotagmin XIII | 0.00939777 |
| RAB30 | RAB30, member RAS oncogene family | 0.00933917 |
| RBM26 | RNA binding motif protein 26 | 0.00927226 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.00923174 |
| NELL1 | NEL-like 1 (chicken) | 0.00902749 |
| KIAA1671 | KIAA1671 | 0.00901978 |
| FOXO3 | forkhead box O3 | 0.00900511 |
| EPAS1 | endothelial PAS domain protein 1 | 0.00900066 |
| ZNF142 | zinc finger protein 142 | 0.0089298 |
| NUP160 | nucleoporin 160kDa | 0.00892742 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 | 0.00886893 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.00876025 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 0.00864397 |
| RNF130 | ring finger protein 130 | 0.00861813 |
| KLHL29 | kelch-like family member 29 | 0.00858047 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.00856093 |
| AP5M1 | adaptor-related protein complex 5, mu 1 subunit | 0.00846717 |
| SAP130 | Sin3A-associated protein, 130kDa | 0.0084374 |
| FASN | fatty acid synthase | 0.00839534 |
| KANTR | KDM5C adjacent non-coding transcript | 0.00834801 |
| SEPTIN9 | septin 9 | 0.00834723 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.00828047 |
| ZNF780B | zinc finger protein 780B | 0.00824787 |
| MCF2L | MCF.2 cell line derived transforming sequence-like | 0.00820385 |
| FKBP9 | FK506 binding protein 9, 63 kDa | 0.00816542 |
| PCDHA6 | protocadherin alpha 6 | 0.00811759 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0080983 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 | 0.0080952 |
| AGBL4 | ATP/GTP binding protein-like 4 | 0.00805395 |
| IGSF9B | immunoglobulin superfamily, member 9B | 0.0080293 |
| TMC5 | transmembrane channel-like 5 | 0.00802572 |
| TAFA5 | TAFA chemokine like family member 5 | 0.00796985 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.167972 |
| PTMA | prothymosin, alpha | -0.15866 |
| TENM1 | teneurin transmembrane protein 1 | -0.140608 |
| ENO1 | enolase 1, (alpha) | -0.123956 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.119589 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0934997 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0912752 |
| CALCA | calcitonin-related polypeptide alpha | -0.0896609 |
| CENPF | centromere protein F, 350/400kDa | -0.0760931 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.070088 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0692894 |
| RPS3 | ribosomal protein S3 | -0.0592004 |
| RPS8 | ribosomal protein S8 | -0.0587017 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0586717 |
| RPS21 | ribosomal protein S21 | -0.0551889 |
| RPS27A | ribosomal protein S27a | -0.0505419 |
| MT2A | metallothionein 2A | -0.0496021 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0494444 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0491368 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0476205 |
| ACTG1 | actin gamma 1 | -0.0473874 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0445093 |
| PEG10 | paternally expressed 10 | -0.0443598 |
| RPLP1 | ribosomal protein, large, P1 | -0.0439073 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0435913 |
| FTL | ferritin, light polypeptide | -0.0432703 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0421348 |
| ZNF292 | zinc finger protein 292 | -0.0417483 |
| PKM | pyruvate kinase, muscle | -0.0413079 |
| TXNRD1 | thioredoxin reductase 1 | -0.0408173 |
| CCDC88A | coiled-coil domain containing 88A | -0.0402598 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0396144 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0395181 |
| PGK1 | phosphoglycerate kinase 1 | -0.0391702 |
| RPL5 | ribosomal protein L5 | -0.03915 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0389634 |
| TMSB10 | thymosin beta 10 | -0.0386273 |
| STC1 | stanniocalcin 1 | -0.0384777 |
| RPL23 | ribosomal protein L23 | -0.0381906 |
| MATR3 | matrin 3 | -0.0379948 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0375168 |
| RPL37A | ribosomal protein L37a | -0.0373962 |
| UBC | ubiquitin C | -0.0372543 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0370343 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0366148 |
| PCBP2 | poly(rC) binding protein 2 | -0.0363341 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0358462 |
| SET | SET nuclear proto-oncogene | -0.0357953 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0354718 |
| SEPTIN7 | septin 7 | -0.0352455 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0345396 |
| VGF | VGF nerve growth factor inducible | -0.034187 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0338001 |
| RPS25 | ribosomal protein S25 | -0.0337306 |
| FUS | FUS RNA binding protein | -0.0336115 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0333562 |
| RPS6 | ribosomal protein S6 | -0.0330442 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0330062 |
| CALR | calreticulin | -0.0327762 |
| RPL8 | ribosomal protein L8 | -0.0327361 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0326378 |
| MAP1B | microtubule-associated protein 1B | -0.0323857 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.032202 |
| RPL26 | ribosomal protein L26 | -0.0316167 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.031513 |
| INHBA | inhibin, beta A | -0.031454 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0313718 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0312579 |
| CANX | calnexin | -0.0312447 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0311876 |
| WDR45B | WD repeat domain 45B | -0.0310997 |
| HMGB2 | high mobility group box 2 | -0.0309898 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0307497 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0302554 |
| RPS16 | ribosomal protein S16 | -0.0302214 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0300214 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0293995 |
| RPS12 | ribosomal protein S12 | -0.0290192 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0289607 |
| RPL35 | ribosomal protein L35 | -0.0288959 |
| MED13L | mediator complex subunit 13-like | -0.0287862 |
| SMC1A | structural maintenance of chromosomes 1A | -0.0287358 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0287199 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0285838 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0284905 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0282042 |
| RTN4 | reticulon 4 | -0.0281345 |
| RPL38 | ribosomal protein L38 | -0.0280868 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0280123 |
| PARD3 | par-3 family cell polarity regulator | -0.0278344 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.027825 |
| NDRG1 | N-myc downstream regulated 1 | -0.0278232 |
| RPL19 | ribosomal protein L19 | -0.027768 |
| POTEF | POTE ankyrin domain family, member F | -0.0276079 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0275037 |
| CA8 | carbonic anhydrase VIII | -0.0274918 |
| LDHA | lactate dehydrogenase A | -0.0273632 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0271883 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0271596 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.02714 |
