| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (hydrochloride) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Imiquimod (hydrochloride)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.348277 |
| FN1 | fibronectin 1 | 0.0990029 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0908625 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0867751 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0860646 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0798208 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0731556 |
| ARRDC3 | arrestin domain containing 3 | 0.0674755 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0580397 |
| NAV2 | neuron navigator 2 | 0.0521359 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0505742 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0503529 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0492134 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0443134 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0421249 |
| SMAD3 | SMAD family member 3 | 0.0414173 |
| MSN | moesin | 0.0384782 |
| KYNU | kynureninase | 0.0371455 |
| RPL3 | ribosomal protein L3 | 0.0365552 |
| ICAM1 | intercellular adhesion molecule 1 | 0.031884 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0315028 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0309193 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.029258 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0291333 |
| AHR | aryl hydrocarbon receptor | 0.0280986 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0273988 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0273648 |
| FLNA | filamin A, alpha | 0.0269503 |
| C3 | complement component 3 | 0.0268616 |
| MKI67 | marker of proliferation Ki-67 | 0.0260492 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0259396 |
| TAPBP | TAP binding protein (tapasin) | 0.025784 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0250406 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0244416 |
| WTAP | Wilms tumor 1 associated protein | 0.0240393 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0236963 |
| PCBP2 | poly(rC) binding protein 2 | 0.0231991 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0230034 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0229114 |
| DSTN | destrin (actin depolymerizing factor) | 0.0223708 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0223088 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0221273 |
| MYOF | myoferlin | 0.0219406 |
| SPAG9 | sperm associated antigen 9 | 0.0218262 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0217885 |
| STC1 | stanniocalcin 1 | 0.0217388 |
| ANLN | anillin, actin binding protein | 0.0216588 |
| NONO | non-POU domain containing, octamer-binding | 0.0206797 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0203798 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0199154 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.01974 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0195106 |
| CENPF | centromere protein F, 350/400kDa | 0.019442 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0194142 |
| OPTN | optineurin | 0.0192276 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0192208 |
| VMP1 | vacuole membrane protein 1 | 0.0190305 |
| ZNF292 | zinc finger protein 292 | 0.018798 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.018734 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0185993 |
| FLNB | filamin B, beta | 0.0185718 |
| ATP13A3 | ATPase type 13A3 | 0.0184683 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0181837 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0178782 |
| PRKCSH | protein kinase C substrate 80K-H | 0.0176708 |
| RASA2 | RAS p21 protein activator 2 | 0.0176063 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0175436 |
| MX1 | MX dynamin-like GTPase 1 | 0.0175089 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0172912 |
| SFTPA2 | surfactant protein A2 | 0.0172015 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0166498 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0165065 |
| RPL4 | ribosomal protein L4 | 0.0163584 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0163523 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0163496 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0163306 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0162704 |
| CEP250 | centrosomal protein 250kDa | 0.016256 |
| APP | amyloid beta (A4) precursor protein | 0.0160722 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0159854 |
| DHFR | dihydrofolate reductase | 0.015674 |
| NUP153 | nucleoporin 153kDa | 0.0156344 |
| VEGFA | vascular endothelial growth factor A | 0.0155378 |
| YEATS2 | YEATS domain containing 2 | 0.0154826 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0154237 |
| TPM3 | tropomyosin 3 | 0.0153872 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0153567 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.015316 |
| CDCP1 | CUB domain containing protein 1 | 0.0152207 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0151846 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0151698 |
| LOXL2 | lysyl oxidase-like 2 | 0.0151345 |
| UBC | ubiquitin C | 0.0150151 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.014954 |
| YBX1 | Y box binding protein 1 | 0.0146535 |
| DUSP5 | dual specificity phosphatase 5 | 0.0145339 |
| RLIM | ring finger protein, LIM domain interacting | 0.0145209 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0145117 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0145091 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0144 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.20313 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.127238 |
| FRMD4A | FERM domain containing 4A | -0.113158 |
| GLIS3 | GLIS family zinc finger 3 | -0.112519 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.107182 |
| IER3 | immediate early response 3 | -0.097586 |
| HLA-B | major histocompatibility complex, class I, B | -0.0967434 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0908596 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0803854 |
| TMSB10 | thymosin beta 10 | -0.0798451 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0791241 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0769315 |
| CDH13 | cadherin 13 | -0.0763826 |
| HMGA2 | high mobility group AT-hook 2 | -0.0704309 |
| FTL | ferritin, light polypeptide | -0.0621827 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0602245 |
| ASPH | aspartate beta-hydroxylase | -0.0539939 |
| RPS6 | ribosomal protein S6 | -0.050732 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0502422 |
| NAV1 | neuron navigator 1 | -0.0493606 |
| PDE10A | phosphodiesterase 10A | -0.0471997 |
| TMEM132D | transmembrane protein 132D | -0.0460598 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0457012 |
| RPL35A | ribosomal protein L35a | -0.0445097 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0443666 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0385733 |
| COL1A1 | collagen, type I, alpha 1 | -0.0370406 |
| DIAPH2 | diaphanous-related formin 2 | -0.0365491 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0363746 |
| RPL37A | ribosomal protein L37a | -0.0360155 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0356185 |
| RPS24 | ribosomal protein S24 | -0.034991 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0348984 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0346256 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0345676 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0345127 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0341676 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0341087 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0334208 |
| COL5A1 | collagen, type V, alpha 1 | -0.0319211 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0318328 |
| RPLP1 | ribosomal protein, large, P1 | -0.031421 |
| RPS8 | ribosomal protein S8 | -0.0314197 |
| GPC6 | glypican 6 | -0.0311941 |
| RPLP2 | ribosomal protein, large, P2 | -0.0300063 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0293993 |
| RPS21 | ribosomal protein S21 | -0.029317 |
| PTMA | prothymosin, alpha | -0.0292433 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0289985 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0287075 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.028628 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0285323 |
| MT2A | metallothionein 2A | -0.0283804 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0282208 |
| BNC2 | basonuclin 2 | -0.0278153 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0268706 |
| RPL9 | ribosomal protein L9 | -0.0265674 |
| INTS6 | integrator complex subunit 6 | -0.0263636 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0262336 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0260629 |
| RPS12 | ribosomal protein S12 | -0.0258869 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.025811 |
| CLMP | CXADR-like membrane protein | -0.0256992 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0250119 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0248042 |
| ATXN1 | ataxin 1 | -0.0247642 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0245444 |
| CTSD | cathepsin D | -0.0242952 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0241961 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0241342 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0239349 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.023908 |
| BICC1 | BicC family RNA binding protein 1 | -0.023821 |
| TMSB4X | thymosin beta 4, X-linked | -0.0236417 |
| RAD51B | RAD51 paralog B | -0.0236145 |
| FBXO11 | F-box protein 11 | -0.0233622 |
| ACTG1 | actin gamma 1 | -0.0233268 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0231796 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0231048 |
| GOLGB1 | golgin B1 | -0.0230507 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0229601 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0226956 |
| NRN1 | neuritin 1 | -0.0225519 |
| VCL | vinculin | -0.0224034 |
| RRBP1 | ribosome binding protein 1 | -0.0222682 |
| TENM2 | teneurin transmembrane protein 2 | -0.0221886 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0221131 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.021914 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.021787 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0216723 |
| RPL19 | ribosomal protein L19 | -0.0216511 |
| KRT19 | keratin 19, type I | -0.0215664 |
| ERBIN | erbb2 interacting protein | -0.0211766 |
| INHBA | inhibin, beta A | -0.0209896 |
| RPL36A | ribosomal protein L36a | -0.0207275 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0204295 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0200908 |
| EFNA5 | ephrin-A5 | -0.0198706 |
| RPL38 | ribosomal protein L38 | -0.0195981 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0195334 |
