| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (hydrochloride) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Imiquimod (hydrochloride)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.147903 |
| COL6A3 | collagen, type VI, alpha 3 | 0.131474 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.092746 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0792436 |
| LOX | lysyl oxidase | 0.0746927 |
| LOXL2 | lysyl oxidase-like 2 | 0.0723995 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0692376 |
| B2M | beta-2-microglobulin | 0.067687 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0637392 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0605008 |
| ZNF395 | zinc finger protein 395 | 0.0600027 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0588786 |
| ARRDC3 | arrestin domain containing 3 | 0.0582767 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.057993 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0574266 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0546137 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0540709 |
| ATP13A3 | ATPase type 13A3 | 0.0508713 |
| NDRG1 | N-myc downstream regulated 1 | 0.0499453 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0474036 |
| ZNF292 | zinc finger protein 292 | 0.0457099 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0454869 |
| MATR3 | matrin 3 | 0.0447593 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0437959 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0423954 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0406659 |
| RTN4 | reticulon 4 | 0.0390464 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.0384043 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0378412 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0377517 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0376628 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0360419 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0359716 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0352499 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0346952 |
| SYNJ2 | synaptojanin 2 | 0.0346689 |
| RBM33 | RNA binding motif protein 33 | 0.0341119 |
| PRSS23 | protease, serine, 23 | 0.0332449 |
| ANXA2 | annexin A2 | 0.0331511 |
| COL3A1 | collagen, type III, alpha 1 | 0.031994 |
| ANO6 | anoctamin 6 | 0.0318801 |
| FAM13A | family with sequence similarity 13, member A | 0.0318781 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0307113 |
| CORO1C | coronin, actin binding protein, 1C | 0.0303738 |
| FBXO7 | F-box protein 7 | 0.0298386 |
| WDR59 | WD repeat domain 59 | 0.0293561 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0293318 |
| PTN | pleiotrophin | 0.0292892 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0289482 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0287323 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0286762 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0280471 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.0277538 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0272027 |
| LONP2 | lon peptidase 2, peroxisomal | 0.0268284 |
| COL1A2 | collagen, type I, alpha 2 | 0.0267546 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0267223 |
| RPL23 | ribosomal protein L23 | 0.0266538 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.026647 |
| SBF2 | SET binding factor 2 | 0.0264278 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase | 0.0262145 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0260653 |
| PGK1 | phosphoglycerate kinase 1 | 0.0259186 |
| ANXA5 | annexin A5 | 0.0258637 |
| TFG | TRK-fused gene | 0.0256256 |
| WTAP | Wilms tumor 1 associated protein | 0.0256082 |
| SMOX | spermine oxidase | 0.0253445 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0253434 |
| HMGA2 | high mobility group AT-hook 2 | 0.0248851 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0247247 |
| YBX1 | Y box binding protein 1 | 0.0247098 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.0245901 |
| H3-3B | H3.3 histone B | 0.0245678 |
| RPL3 | ribosomal protein L3 | 0.0244314 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0241983 |
| TMEM59 | transmembrane protein 59 | 0.0241841 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.024159 |
| CTSB | cathepsin B | 0.0240762 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.0240229 |
| SMTN | smoothelin | 0.0238767 |
| RND3 | Rho family GTPase 3 | 0.0238567 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0237722 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.023571 |
| CALU | calumenin | 0.0234965 |
| UBC | ubiquitin C | 0.0230739 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0230675 |
| RBM15 | RNA binding motif protein 15 | 0.0227325 |
| FNIP1 | folliculin interacting protein 1 | 0.0224191 |
| SERINC1 | serine incorporator 1 | 0.0223604 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0220509 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0218643 |
| RLF | rearranged L-myc fusion | 0.0218619 |
| TNNC1 | troponin C type 1 (slow) | 0.0218385 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0218088 |
| CSNK1E | casein kinase 1, epsilon | 0.0216444 |
| OST4 | oligosaccharyltransferase 4 homolog (S. cerevisiae) | 0.0214529 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.0214229 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0213172 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0212896 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0211194 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.0866789 |
| TMSB10 | thymosin beta 10 | -0.0807242 |
| IL6 | interleukin 6 | -0.0531888 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0478796 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0474734 |
| MORF4L2 | mortality factor 4 like 2 | -0.046774 |
| EGFR | epidermal growth factor receptor | -0.0416916 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0407936 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0399994 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0396047 |
| ACTG1 | actin gamma 1 | -0.0386836 |
| EFNA5 | ephrin-A5 | -0.0360516 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0360318 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0347781 |
| HLA-B | major histocompatibility complex, class I, B | -0.0346824 |
| SMYD3 | SET and MYND domain containing 3 | -0.0343835 |
| NKTR | natural killer cell triggering receptor | -0.0339031 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0336068 |
| TNS3 | tensin 3 | -0.0316975 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.031333 |
| CDH13 | cadherin 13 | -0.0313259 |
| RPS6 | ribosomal protein S6 | -0.0297304 |
| RAD51B | RAD51 paralog B | -0.0289718 |
| PRKCA | protein kinase C, alpha | -0.0289616 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0284554 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0279725 |
| NAV1 | neuron navigator 1 | -0.0277403 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0273436 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0272357 |
| CADM1 | cell adhesion molecule 1 | -0.0266888 |
| RPL35A | ribosomal protein L35a | -0.0266735 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0264718 |
| RPS19 | ribosomal protein S19 | -0.0262929 |
| RUNX1 | runt-related transcription factor 1 | -0.0260805 |
| EXOC4 | exocyst complex component 4 | -0.0258958 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0258546 |
| DST | dystonin | -0.0257621 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0256881 |
| CCNI | cyclin I | -0.0252242 |
| ERBIN | erbb2 interacting protein | -0.0249201 |
| RPLP1 | ribosomal protein, large, P1 | -0.0248572 |
| FRMD4A | FERM domain containing 4A | -0.0245235 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0244189 |
| JMJD1C | jumonji domain containing 1C | -0.0244059 |
| TJP1 | tight junction protein 1 | -0.024379 |
| GLG1 | golgi glycoprotein 1 | -0.0242823 |
| NAV2 | neuron navigator 2 | -0.0241412 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0239427 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0237353 |
| VEGFC | vascular endothelial growth factor C | -0.023712 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0231008 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0229238 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0228565 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0224736 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0224048 |
| CTBP2 | C-terminal binding protein 2 | -0.0222421 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0222363 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0220222 |
| VCL | vinculin | -0.0220113 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.021991 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0218102 |
| COG6 | component of oligomeric golgi complex 6 | -0.0218045 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0217062 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0216737 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0216242 |
| KRIT1 | KRIT1, ankyrin repeat containing | -0.0214267 |
| CENPF | centromere protein F, 350/400kDa | -0.0213658 |
| CCDC88A | coiled-coil domain containing 88A | -0.0213547 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | -0.0213159 |
| PKM | pyruvate kinase, muscle | -0.0213159 |
| TAGLN2 | transgelin 2 | -0.0209995 |
| IKBIP | IKBKB interacting protein | -0.0209941 |
| JAZF1 | JAZF zinc finger 1 | -0.0208653 |
| LMO7 | LIM domain 7 | -0.0207344 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0207181 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0206215 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0206124 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0205592 |
| NUDCD3 | NudC domain containing 3 | -0.0205485 |
| DYNC2I1 | dynein 2 intermediate chain 1 | -0.0204682 |
| CDK19 | cyclin-dependent kinase 19 | -0.0203789 |
| RBM39 | RNA binding motif protein 39 | -0.0202964 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.020247 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0201941 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0200708 |
| THOC2 | THO complex 2 | -0.0199806 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0199324 |
| PDE8A | phosphodiesterase 8A | -0.0199314 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | -0.0198342 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0197219 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0196496 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0196132 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0194703 |
| SIK3 | SIK family kinase 3 | -0.0194688 |
| SEC61G | Sec61 gamma subunit | -0.0191878 |
| LMNA | lamin A/C | -0.0191023 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.018899 |
| ENO1 | enolase 1, (alpha) | -0.0188687 |
| WWOX | WW domain containing oxidoreductase | -0.0187632 |
| RPL31 | ribosomal protein L31 | -0.0187492 |
