| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (hydrochloride) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Imiquimod (hydrochloride)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.0877162 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.067361 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0570556 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0568884 |
| NUP58 | nucleoporin 58 | 0.0505008 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0478199 |
| CEP250 | centrosomal protein 250kDa | 0.0473551 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0444065 |
| PKM | pyruvate kinase, muscle | 0.0425444 |
| FLNB | filamin B, beta | 0.0415681 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0381126 |
| NUP153 | nucleoporin 153kDa | 0.0376594 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0365227 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0361608 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0352163 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0351295 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0350816 |
| XPO6 | exportin 6 | 0.0349749 |
| DSCAM | Down syndrome cell adhesion molecule | 0.03483 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0344884 |
| NBAS | neuroblastoma amplified sequence | 0.03389 |
| ATP13A3 | ATPase type 13A3 | 0.0338013 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0327579 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0325995 |
| CD44 | CD44 molecule (Indian blood group) | 0.0325967 |
| RBM39 | RNA binding motif protein 39 | 0.0325333 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0317859 |
| UBC | ubiquitin C | 0.0314051 |
| MATR3 | matrin 3 | 0.031297 |
| TFG | TRK-fused gene | 0.0309937 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0307185 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0305179 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0298811 |
| AHNAK | AHNAK nucleoprotein | 0.0297445 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.029666 |
| ARRDC3 | arrestin domain containing 3 | 0.0292284 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0291538 |
| RPL23 | ribosomal protein L23 | 0.029063 |
| SMAD3 | SMAD family member 3 | 0.0289702 |
| RPL3 | ribosomal protein L3 | 0.0286565 |
| RNF145 | ring finger protein 145 | 0.0286412 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0285345 |
| CLTC | clathrin, heavy chain (Hc) | 0.0284879 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0284517 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0283598 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.0282882 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0279071 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0278988 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0278365 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0277756 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.027758 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0277373 |
| MSN | moesin | 0.0275991 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0274743 |
| ANGPTL4 | angiopoietin-like 4 | 0.0274353 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0272157 |
| WAC | WW domain containing adaptor with coiled-coil | 0.027041 |
| UBP1 | upstream binding protein 1 (LBP-1a) | 0.0270214 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.0268916 |
| CASC3 | cancer susceptibility candidate 3 | 0.0267859 |
| ACER3 | alkaline ceramidase 3 | 0.026671 |
| CALU | calumenin | 0.0266375 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0266224 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0265615 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0265499 |
| TFRC | transferrin receptor | 0.0263308 |
| YAP1 | Yes-associated protein 1 | 0.0261417 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0261198 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0257445 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0256529 |
| NHSL1 | NHS-like 1 | 0.0255607 |
| RANBP2 | RAN binding protein 2 | 0.0253645 |
| SETD5 | SET domain containing 5 | 0.0252744 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0252086 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0251965 |
| KLC1 | kinesin light chain 1 | 0.0250585 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0250371 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.02485 |
| CCDC88A | coiled-coil domain containing 88A | 0.0248488 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0244397 |
| RTN4 | reticulon 4 | 0.0243191 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0242116 |
| CUL4B | cullin 4B | 0.0241703 |
| PHF20 | PHD finger protein 20 | 0.0239815 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0238547 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0237799 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0235744 |
| CAPRIN2 | caprin family member 2 | 0.023469 |
| KIF23 | kinesin family member 23 | 0.0234281 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0234121 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0233583 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.023112 |
| LMNB1 | lamin B1 | 0.0231 |
| CEP70 | centrosomal protein 70kDa | 0.0230878 |
| MPHOSPH9 | M-phase phosphoprotein 9 | 0.0229757 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0227396 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0227306 |
| KIF5B | kinesin family member 5B | 0.0226988 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0226752 |
| TPM4 | tropomyosin 4 | 0.0226133 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.111733 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.107206 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0719222 |
| RPLP1 | ribosomal protein, large, P1 | -0.067935 |
| TMSB10 | thymosin beta 10 | -0.0676961 |
| SQSTM1 | sequestosome 1 | -0.0524322 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0503384 |
| HMGA2 | high mobility group AT-hook 2 | -0.0488173 |
| ANXA1 | annexin A1 | -0.0430251 |
| GNAS | GNAS complex locus | -0.041703 |
| RPL12 | ribosomal protein L12 | -0.0403642 |
| RPS23 | ribosomal protein S23 | -0.0384521 |
| ENO1 | enolase 1, (alpha) | -0.0381505 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0379143 |
| RPL35A | ribosomal protein L35a | -0.0356429 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0354973 |
| EGR1 | early growth response 1 | -0.0350879 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.03474 |
| IER3 | immediate early response 3 | -0.0344782 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0342667 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0339655 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0334581 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.032659 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0322961 |
| RPS8 | ribosomal protein S8 | -0.031532 |
| MYO9A | myosin IXA | -0.0314899 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0313767 |
| RPL31 | ribosomal protein L31 | -0.0309753 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0304958 |
| SVIL | supervillin | -0.0301329 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0300411 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0299211 |
| RPL11 | ribosomal protein L11 | -0.0297454 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0297247 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0296062 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.029594 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0292422 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0291548 |
| RPLP0 | ribosomal protein, large, P0 | -0.0290882 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0290238 |
| BPTF | bromodomain PHD finger transcription factor | -0.028603 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0284469 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0283467 |
| USP34 | ubiquitin specific peptidase 34 | -0.0280328 |
| JMJD1C | jumonji domain containing 1C | -0.0278378 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0275879 |
| STK4 | serine/threonine kinase 4 | -0.0275468 |
| MT2A | metallothionein 2A | -0.0266473 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0264298 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0264244 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0260679 |
| RPL36 | ribosomal protein L36 | -0.0260528 |
| PCNX4 | pecanex 4 | -0.0259863 |
| MAP1B | microtubule-associated protein 1B | -0.0259619 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.025941 |
| GPC6 | glypican 6 | -0.0259327 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0255928 |
| FNDC3A | fibronectin type III domain containing 3A | -0.02558 |
| HDAC9 | histone deacetylase 9 | -0.0255691 |
| CREBBP | CREB binding protein | -0.0253768 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0253281 |
| RPL37 | ribosomal protein L37 | -0.0252633 |
| RPS29 | ribosomal protein S29 | -0.0252581 |
| TOR1AIP2 | torsin A interacting protein 2 | -0.0251573 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0251453 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0250796 |
| UBE3C | ubiquitin protein ligase E3C | -0.0248919 |
| S100A10 | S100 calcium binding protein A10 | -0.0247404 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.024673 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0239943 |
| RPL19 | ribosomal protein L19 | -0.0237514 |
| PFN1 | profilin 1 | -0.0237269 |
| FNIP1 | folliculin interacting protein 1 | -0.023554 |
| TOP1 | topoisomerase (DNA) I | -0.0233726 |
| RPL37A | ribosomal protein L37a | -0.0233287 |
| GLG1 | golgi glycoprotein 1 | -0.0233069 |
| RPL34 | ribosomal protein L34 | -0.0232582 |
| RPS6 | ribosomal protein S6 | -0.0231072 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0229095 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0225468 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0223197 |
| ATG7 | autophagy related 7 | -0.0222035 |
| FTL | ferritin, light polypeptide | -0.0221703 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0219743 |
| RPS14 | ribosomal protein S14 | -0.0219632 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0219322 |
| TBCA | tubulin folding cofactor A | -0.0218908 |
| RBM26 | RNA binding motif protein 26 | -0.0217419 |
| TP53 | tumor protein p53 | -0.0215836 |
| TOM1L2 | target of myb1-like 2 (chicken) | -0.0214009 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0213437 |
| MORF4L2 | mortality factor 4 like 2 | -0.0211689 |
| DEK | DEK proto-oncogene | -0.0211369 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0208109 |
| ZC3H6 | zinc finger CCCH-type containing 6 | -0.0207381 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0207366 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0207015 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0206959 |
| HLA-B | major histocompatibility complex, class I, B | -0.0206062 |
| CCAR1 | cell division cycle and apoptosis regulator 1 | -0.020514 |
