| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (hydrochloride) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Imiquimod (hydrochloride)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EZR | ezrin | 0.0888184 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0790079 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0750152 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0702221 |
| DSPP | dentin sialophosphoprotein | 0.0620569 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0608939 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0575384 |
| FLNA | filamin A, alpha | 0.0543589 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0462526 |
| ACTN4 | actinin, alpha 4 | 0.0461387 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0457202 |
| RBM39 | RNA binding motif protein 39 | 0.0444071 |
| KRT18 | keratin 18, type I | 0.0437299 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0432029 |
| UBC | ubiquitin C | 0.0431766 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0426953 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0421948 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0411144 |
| PKM | pyruvate kinase, muscle | 0.0410382 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0407858 |
| MATR3 | matrin 3 | 0.0406492 |
| PTMA | prothymosin, alpha | 0.0389382 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0380975 |
| EPCAM | epithelial cell adhesion molecule | 0.0377226 |
| YAP1 | Yes-associated protein 1 | 0.0374725 |
| RPL3 | ribosomal protein L3 | 0.0366154 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0349898 |
| CCND1 | cyclin D1 | 0.0343693 |
| NCKAP1 | NCK-associated protein 1 | 0.0337864 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0335216 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0331048 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0325456 |
| RPL4 | ribosomal protein L4 | 0.0324174 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0317684 |
| TPM4 | tropomyosin 4 | 0.0317165 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0311687 |
| XPO1 | exportin 1 | 0.0307954 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0307231 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0302747 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0301049 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.030046 |
| H1-0 | H1.0 linker histone | 0.0299436 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0299236 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0298225 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0295764 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0294585 |
| AHNAK | AHNAK nucleoprotein | 0.029432 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0293109 |
| PLEC | plectin | 0.0292372 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0291447 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0290285 |
| TPM3 | tropomyosin 3 | 0.0286844 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0282922 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0282079 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0279088 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.027427 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.027425 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0274216 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0272977 |
| HMGB2 | high mobility group box 2 | 0.0272893 |
| PCBP2 | poly(rC) binding protein 2 | 0.0268009 |
| MKRN1 | makorin ring finger protein 1 | 0.0266821 |
| DHFR | dihydrofolate reductase | 0.0261275 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0259466 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0258707 |
| HLA-A | major histocompatibility complex, class I, A | 0.025749 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0256493 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0251459 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0251125 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0251019 |
| RHEB | Ras homolog enriched in brain | 0.0248571 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0242123 |
| CALR | calreticulin | 0.0240857 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0240429 |
| NPTN | neuroplastin | 0.0240375 |
| PAPOLA | poly(A) polymerase alpha | 0.0239611 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0239287 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0238444 |
| MYO10 | myosin X | 0.0238428 |
| TFRC | transferrin receptor | 0.0238099 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0237989 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0237832 |
| KIF5B | kinesin family member 5B | 0.0236638 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0236136 |
| MYO5B | myosin VB | 0.0234648 |
| APP | amyloid beta (A4) precursor protein | 0.0228365 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.0228267 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0227676 |
| YBX1 | Y box binding protein 1 | 0.0225858 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0225351 |
| EWSR1 | EWS RNA-binding protein 1 | 0.022508 |
| HBP1 | HMG-box transcription factor 1 | 0.022293 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.022072 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0219436 |
| EMP1 | epithelial membrane protein 1 | 0.0219071 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0216332 |
| PGK1 | phosphoglycerate kinase 1 | 0.0215838 |
| RACK1 | receptor for activated C kinase 1 | 0.0211647 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0211496 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0210886 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.0795117 |
| TMSB10 | thymosin beta 10 | -0.0533357 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0374159 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0338206 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0336613 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0333645 |
| RPL35A | ribosomal protein L35a | -0.030565 |
| RPL37A | ribosomal protein L37a | -0.029866 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.029499 |
| BPTF | bromodomain PHD finger transcription factor | -0.0272597 |
| BCL2L1 | BCL2-like 1 | -0.0259109 |
| RPS6 | ribosomal protein S6 | -0.0254384 |
| EGR1 | early growth response 1 | -0.0254255 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0250787 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.025077 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0242284 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0223206 |
| RPL19 | ribosomal protein L19 | -0.0222597 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0222016 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0221265 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0217378 |
| RPL31 | ribosomal protein L31 | -0.0203735 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0202395 |
| RIGI | RNA sensor RIG-I | -0.0199978 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0198654 |
| SBF2 | SET binding factor 2 | -0.0197426 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0197258 |
| NF1 | neurofibromin 1 | -0.0196104 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0195206 |
| NEBL | nebulette | -0.0192931 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0192856 |
| TGFA | transforming growth factor, alpha | -0.0190667 |
| MX2 | MX dynamin-like GTPase 2 | -0.0189608 |
| NHSL1 | NHS-like 1 | -0.0189535 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0188223 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0187667 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0187231 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.018604 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0183953 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0182913 |
| RPLP1 | ribosomal protein, large, P1 | -0.0182594 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0182438 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0180085 |
| EHBP1 | EH domain binding protein 1 | -0.0176227 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0175449 |
| NRP1 | neuropilin 1 | -0.0172986 |
| ETV6 | ets variant 6 | -0.0172345 |
| PLSCR1 | phospholipid scramblase 1 | -0.0172102 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0171499 |
| COG5 | component of oligomeric golgi complex 5 | -0.0168835 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0167603 |
| CADPS | Ca++-dependent secretion activator | -0.0167198 |
| RPLP2 | ribosomal protein, large, P2 | -0.0165581 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.016527 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0164702 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0164646 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0163768 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0163084 |
| RPL12 | ribosomal protein L12 | -0.0158508 |
| HM13 | histocompatibility (minor) 13 | -0.0157485 |
| RPS5 | ribosomal protein S5 | -0.0156381 |
| IER3 | immediate early response 3 | -0.0153086 |
| RASA2 | RAS p21 protein activator 2 | -0.015173 |
| RPL9 | ribosomal protein L9 | -0.0151258 |
| RPS19 | ribosomal protein S19 | -0.0150705 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0150383 |
| PTEN | phosphatase and tensin homolog | -0.0150197 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0149751 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0147399 |
| ASPH | aspartate beta-hydroxylase | -0.0145632 |
| RPL35 | ribosomal protein L35 | -0.0145621 |
| SETX | senataxin | -0.0145451 |
| RPL34 | ribosomal protein L34 | -0.0145381 |
| CUX1 | cut-like homeobox 1 | -0.0145351 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0145051 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0144974 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0144935 |
| PHF14 | PHD finger protein 14 | -0.0144849 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0144639 |
| TMEM87A | transmembrane protein 87A | -0.0142439 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0142357 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0141343 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0141235 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0141004 |
| CLDN4 | claudin 4 | -0.0138994 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0138977 |
| RUNX1 | runt-related transcription factor 1 | -0.0138713 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.013828 |
| EXOC4 | exocyst complex component 4 | -0.0137335 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0137196 |
| JMJD1C | jumonji domain containing 1C | -0.0135931 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0134607 |
| ATG7 | autophagy related 7 | -0.0133849 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0133783 |
| GOSR1 | golgi SNAP receptor complex member 1 | -0.0133076 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0132723 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0130364 |
| RPL26 | ribosomal protein L26 | -0.0130049 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0129992 |
| HDAC9 | histone deacetylase 9 | -0.0129192 |
