| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (hydrochloride) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Imiquimod (hydrochloride)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STC1 | stanniocalcin 1 | 0.0583992 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0401427 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0330198 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0323856 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0303264 |
| NAV2 | neuron navigator 2 | 0.0264765 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0235665 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0219187 |
| RPL3 | ribosomal protein L3 | 0.021803 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0203334 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0193564 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0187589 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0169973 |
| COG6 | component of oligomeric golgi complex 6 | 0.0156102 |
| SMAD3 | SMAD family member 3 | 0.0145521 |
| SPAG9 | sperm associated antigen 9 | 0.0140658 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0133306 |
| FLNA | filamin A, alpha | 0.0132553 |
| MKI67 | marker of proliferation Ki-67 | 0.013207 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0129993 |
| NGLY1 | N-glycanase 1 | 0.0125967 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.01251 |
| TNPO1 | transportin 1 | 0.0124797 |
| MSI2 | musashi RNA-binding protein 2 | 0.0124355 |
| SMOX | spermine oxidase | 0.0121159 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0118507 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.011622 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0115146 |
| ARRDC3 | arrestin domain containing 3 | 0.0112877 |
| NCKAP1 | NCK-associated protein 1 | 0.0108391 |
| DUSP10 | dual specificity phosphatase 10 | 0.0107241 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0105691 |
| LMO7 | LIM domain 7 | 0.0103725 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0100757 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0100585 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0100395 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.00988301 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.00977605 |
| DHFR | dihydrofolate reductase | 0.0097735 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 0.00966232 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.00942827 |
| TRPC4 | transient receptor potential cation channel, subfamily C, member 4 | 0.00926451 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.00920494 |
| USP3 | ubiquitin specific peptidase 3 | 0.00915523 |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit | 0.00911443 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.00877527 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00866827 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.00866645 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 | 0.00845449 |
| PCBP2 | poly(rC) binding protein 2 | 0.00843493 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.00842332 |
| RPL4 | ribosomal protein L4 | 0.00820281 |
| CENPF | centromere protein F, 350/400kDa | 0.00815591 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.00815343 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.00804843 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.00788163 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.00786513 |
| PTEN | phosphatase and tensin homolog | 0.00785186 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.00782269 |
| UBAP2L | ubiquitin associated protein 2-like | 0.00774282 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.00774274 |
| FAM13A | family with sequence similarity 13, member A | 0.00773656 |
| CKAP5 | cytoskeleton associated protein 5 | 0.00770207 |
| GOLGA4 | golgin A4 | 0.00768661 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | 0.00764736 |
| SRP54 | signal recognition particle 54kDa | 0.00753864 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0075026 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0074949 |
| SP3 | Sp3 transcription factor | 0.00743296 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.00741109 |
| CKAP2 | cytoskeleton associated protein 2 | 0.00740171 |
| CLINT1 | clathrin interactor 1 | 0.00738602 |
| OGA | O-GlcNAcase | 0.00734844 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.00723208 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.00722982 |
| ZNF451 | zinc finger protein 451 | 0.00715716 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.00714994 |
| APAF1 | apoptotic peptidase activating factor 1 | 0.0071394 |
| GOLGA2 | golgin A2 | 0.00711634 |
| PRKCSH | protein kinase C substrate 80K-H | 0.00708385 |
| DSE | dermatan sulfate epimerase | 0.00699973 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.00697747 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | 0.00691906 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.00691626 |
| TMEM39A | transmembrane protein 39A | 0.00690256 |
| COG3 | component of oligomeric golgi complex 3 | 0.00687298 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.00680468 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.00679066 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.00675325 |
| NUP58 | nucleoporin 58 | 0.00673481 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.00672969 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0067169 |
| NBAS | neuroblastoma amplified sequence | 0.00668234 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.00666301 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.00659841 |
| RNF145 | ring finger protein 145 | 0.00653065 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00640924 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.00638344 |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 | 0.00636614 |
| CDK17 | cyclin-dependent kinase 17 | 0.00628213 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.198319 |
| FN1 | fibronectin 1 | -0.197999 |
| COL6A3 | collagen, type VI, alpha 3 | -0.187047 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.156351 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.146744 |
| COL1A1 | collagen, type I, alpha 1 | -0.145401 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.133156 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.131752 |
| COL1A2 | collagen, type I, alpha 2 | -0.107946 |
| HMGA2 | high mobility group AT-hook 2 | -0.104935 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0960385 |
| INHBA | inhibin, beta A | -0.0947774 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0915901 |
| MYO10 | myosin X | -0.0870595 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0839471 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0829903 |
| HLA-B | major histocompatibility complex, class I, B | -0.0767859 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0707449 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0706292 |
| EMP1 | epithelial membrane protein 1 | -0.0695084 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0692985 |
| TMSB10 | thymosin beta 10 | -0.0685816 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0685602 |
| ACTG1 | actin gamma 1 | -0.0660757 |
| ASPH | aspartate beta-hydroxylase | -0.0658944 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0591941 |
| RAI14 | retinoic acid induced 14 | -0.0582017 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0562756 |
| FBN1 | fibrillin 1 | -0.0556572 |
| COL6A1 | collagen, type VI, alpha 1 | -0.053207 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0526466 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0514886 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0512542 |
| FRMD4A | FERM domain containing 4A | -0.0511584 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0511144 |
| RPS6 | ribosomal protein S6 | -0.0505809 |
| NAV1 | neuron navigator 1 | -0.0498415 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0489531 |
| OXR1 | oxidation resistance 1 | -0.0474182 |
| MMP1 | matrix metallopeptidase 1 | -0.0464374 |
| GLIS3 | GLIS family zinc finger 3 | -0.046126 |
| AHNAK | AHNAK nucleoprotein | -0.0451068 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0443096 |
| CDH13 | cadherin 13 | -0.0431913 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0423547 |
| CAVIN1 | caveolae associated protein 1 | -0.0408666 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0398526 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.038859 |
| B2M | beta-2-microglobulin | -0.0388379 |
| TPM4 | tropomyosin 4 | -0.0371905 |
| KIAA1549L | KIAA1549-like | -0.0362097 |
| COL3A1 | collagen, type III, alpha 1 | -0.0354499 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0353407 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0344937 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0344184 |
| CLMP | CXADR-like membrane protein | -0.0343388 |
| RPLP1 | ribosomal protein, large, P1 | -0.0341057 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0336087 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0330606 |
| DIAPH2 | diaphanous-related formin 2 | -0.032277 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0309216 |
| PRSS23 | protease, serine, 23 | -0.0306278 |
| CD44 | CD44 molecule (Indian blood group) | -0.0302443 |
| CALD1 | caldesmon 1 | -0.0299953 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0299247 |
| MED13L | mediator complex subunit 13-like | -0.0299001 |
| CANX | calnexin | -0.0297179 |
| SEPTIN11 | septin 11 | -0.0294893 |
| CALR | calreticulin | -0.0292136 |
| PRR16 | proline rich 16 | -0.0290307 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0282122 |
| HLA-A | major histocompatibility complex, class I, A | -0.0278214 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0273225 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0268374 |
| PRRX1 | paired related homeobox 1 | -0.0265894 |
| RPL34 | ribosomal protein L34 | -0.0261495 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0258442 |
| VCAN | versican | -0.0255817 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0254209 |
| RPS8 | ribosomal protein S8 | -0.024928 |
| POTEF | POTE ankyrin domain family, member F | -0.0248205 |
| FTL | ferritin, light polypeptide | -0.0246511 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0246485 |
| TMEM165 | transmembrane protein 165 | -0.0244851 |
| MAP1B | microtubule-associated protein 1B | -0.0243043 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0241801 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0241525 |
| MAP4 | microtubule-associated protein 4 | -0.0241492 |
| IER3 | immediate early response 3 | -0.0240721 |
| FOXP1 | forkhead box P1 | -0.0238883 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0237571 |
| DST | dystonin | -0.0237083 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.023611 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0234423 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0230023 |
| FRMD6 | FERM domain containing 6 | -0.0227409 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0226331 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0225843 |
| LYST | lysosomal trafficking regulator | -0.0223236 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0222085 |
