| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (maleate) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Imiquimod (maleate)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.182273 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.114877 |
| MSI2 | musashi RNA-binding protein 2 | 0.0756991 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0740558 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0687708 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0668443 |
| CD109 | CD109 molecule | 0.0619325 |
| GOLGA4 | golgin A4 | 0.0575714 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0554328 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0553961 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0546951 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0542838 |
| AUTS2 | autism susceptibility candidate 2 | 0.0516916 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0485021 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0475239 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.044925 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0448949 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0440601 |
| GPC6 | glypican 6 | 0.0418644 |
| DST | dystonin | 0.0413231 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0412613 |
| WTAP | Wilms tumor 1 associated protein | 0.0411735 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0404706 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0385896 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0379792 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0378903 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0373891 |
| FMNL2 | formin-like 2 | 0.0373223 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0366594 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.036292 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0360817 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0359623 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.035075 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0347404 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.034495 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0342089 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0341841 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0337975 |
| RND3 | Rho family GTPase 3 | 0.0336044 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0334783 |
| SQSTM1 | sequestosome 1 | 0.0324665 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0324426 |
| HELZ | helicase with zinc finger | 0.0322577 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0322288 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0308667 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0306544 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0303341 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0302615 |
| SPAG9 | sperm associated antigen 9 | 0.0301887 |
| MMP12 | matrix metallopeptidase 12 | 0.0299889 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0298539 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0298178 |
| FRMD5 | FERM domain containing 5 | 0.0295792 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0294453 |
| CDC73 | cell division cycle 73 | 0.0289923 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0289345 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0287432 |
| QKI | QKI, KH domain containing, RNA binding | 0.0279037 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0274182 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0268681 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0268604 |
| PRKD1 | protein kinase D1 | 0.026818 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 0.0266993 |
| JUN | jun proto-oncogene | 0.026496 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0264125 |
| AHNAK | AHNAK nucleoprotein | 0.0263625 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0263215 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0262566 |
| ZNF292 | zinc finger protein 292 | 0.0261323 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0261239 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.025949 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.025765 |
| RLF | rearranged L-myc fusion | 0.0256693 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0256557 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0252778 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0252287 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0252143 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0250337 |
| SBF2 | SET binding factor 2 | 0.0250131 |
| LPCAT2 | lysophosphatidylcholine acyltransferase 2 | 0.0247742 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0247613 |
| UBTD2 | ubiquitin domain containing 2 | 0.0244586 |
| USP3 | ubiquitin specific peptidase 3 | 0.0242884 |
| TP53BP2 | tumor protein p53 binding protein 2 | 0.0241993 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0240325 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0239399 |
| DENND5A | DENN/MADD domain containing 5A | 0.0236764 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0236135 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0236126 |
| OGA | O-GlcNAcase | 0.0235971 |
| COG5 | component of oligomeric golgi complex 5 | 0.0234625 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.0234085 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0230764 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0230762 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0230466 |
| FGF13 | fibroblast growth factor 13 | 0.0230264 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0228661 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0228211 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.022818 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.022809 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.178637 |
| PODXL | podocalyxin-like | -0.173149 |
| PLAT | plasminogen activator, tissue | -0.151282 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.131973 |
| LOX | lysyl oxidase | -0.106843 |
| CD44 | CD44 molecule (Indian blood group) | -0.105119 |
| NAV1 | neuron navigator 1 | -0.0884802 |
| VIM | vimentin | -0.0766924 |
| MT2A | metallothionein 2A | -0.0762772 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0701495 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0684156 |
| COL5A1 | collagen, type V, alpha 1 | -0.0633766 |
| LMNA | lamin A/C | -0.0568422 |
| CANX | calnexin | -0.0567943 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0544618 |
| CENPF | centromere protein F, 350/400kDa | -0.0539485 |
| SEPTIN9 | septin 9 | -0.0512002 |
| THBS2 | thrombospondin 2 | -0.0507325 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.04513 |
| SP3 | Sp3 transcription factor | -0.0443644 |
| CAVIN1 | caveolae associated protein 1 | -0.0429387 |
| STC1 | stanniocalcin 1 | -0.0421755 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0413859 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0408502 |
| VEGFA | vascular endothelial growth factor A | -0.0406931 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0395302 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0394706 |
| CALR | calreticulin | -0.0385238 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0383839 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0383295 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0380984 |
| RNF213 | ring finger protein 213 | -0.037807 |
| CEP170 | centrosomal protein 170kDa | -0.0376685 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0367437 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0367092 |
| S100A10 | S100 calcium binding protein A10 | -0.0362969 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0359979 |
| NDRG1 | N-myc downstream regulated 1 | -0.0357345 |
| FLNA | filamin A, alpha | -0.0352129 |
| COL5A2 | collagen, type V, alpha 2 | -0.0349713 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0348061 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0322388 |
| RPS2 | ribosomal protein S2 | -0.0316637 |
| RBM25 | RNA binding motif protein 25 | -0.0308122 |
| CD99 | CD99 molecule | -0.0302821 |
| FSTL1 | follistatin-like 1 | -0.0301403 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0300435 |
| EHBP1 | EH domain binding protein 1 | -0.0297395 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0296812 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0294806 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0294662 |
| SVIL | supervillin | -0.0292698 |
| DOCK5 | dedicator of cytokinesis 5 | -0.029088 |
| PLEC | plectin | -0.0282672 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0282218 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0275127 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0273021 |
| COL1A2 | collagen, type I, alpha 2 | -0.027105 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0269853 |
| POTEF | POTE ankyrin domain family, member F | -0.0269789 |
| GOLGB1 | golgin B1 | -0.0265988 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0265987 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0264953 |
| SFTPA2 | surfactant protein A2 | -0.0263943 |
| RRBP1 | ribosome binding protein 1 | -0.0263269 |
| TPM4 | tropomyosin 4 | -0.0260939 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0258596 |
| CDK13 | cyclin-dependent kinase 13 | -0.0258264 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0258036 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0253643 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0251692 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0250213 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0248749 |
| HLA-C | major histocompatibility complex, class I, C | -0.0247584 |
| MKI67 | marker of proliferation Ki-67 | -0.0246364 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0241479 |
| ANKRD36 | ankyrin repeat domain 36 | -0.0241085 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0239736 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0239552 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0239133 |
| LOXL2 | lysyl oxidase-like 2 | -0.0237557 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0236315 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.023611 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0235385 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0235321 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) | -0.0233668 |
| DNMBP | dynamin binding protein | -0.0233347 |
| TMSB10 | thymosin beta 10 | -0.0231303 |
| ANXA4 | annexin A4 | -0.0227956 |
| FAM219A | family with sequence similarity 219, member A | -0.0227923 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | -0.022682 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.022657 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0224331 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0223179 |
| PMP22 | peripheral myelin protein 22 | -0.0221954 |
| EFNA5 | ephrin-A5 | -0.0221711 |
| UBXN4 | UBX domain protein 4 | -0.0221687 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0220777 |
| NAV2 | neuron navigator 2 | -0.021764 |
| MSN | moesin | -0.021754 |
