| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (maleate) perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Imiquimod (maleate)_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.120531 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0719768 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0669469 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0632401 |
| NEK7 | NIMA-related kinase 7 | 0.0590037 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0577545 |
| TMEM41B | transmembrane protein 41B | 0.0566277 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0559792 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0559488 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0546885 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0521861 |
| ECT2 | epithelial cell transforming 2 | 0.0459529 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0442988 |
| THOC1 | THO complex 1 | 0.0436038 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0434923 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0430188 |
| TXNRD1 | thioredoxin reductase 1 | 0.0423472 |
| TNPO1 | transportin 1 | 0.0392195 |
| MATR3 | matrin 3 | 0.038745 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0369631 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0366205 |
| CDK17 | cyclin-dependent kinase 17 | 0.0364113 |
| CPOX | coproporphyrinogen oxidase | 0.034833 |
| MGAT4C | MGAT4 family, member C | 0.0346448 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0342777 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0338368 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0336968 |
| CCNL1 | cyclin L1 | 0.0329508 |
| GASK1B | golgi associated kinase 1B | 0.0328384 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0326917 |
| RPL4 | ribosomal protein L4 | 0.03229 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0318764 |
| CLDN1 | claudin 1 | 0.0315759 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.03136 |
| ETNK1 | ethanolamine kinase 1 | 0.0312475 |
| OXR1 | oxidation resistance 1 | 0.0298563 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0297687 |
| ANXA1 | annexin A1 | 0.029067 |
| OGA | O-GlcNAcase | 0.0290605 |
| NCKAP1 | NCK-associated protein 1 | 0.0287707 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | 0.0286561 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0285728 |
| WDR43 | WD repeat domain 43 | 0.0282856 |
| AXIN2 | axin 2 | 0.0282124 |
| RNF145 | ring finger protein 145 | 0.0281898 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0277806 |
| KIF5B | kinesin family member 5B | 0.0276418 |
| LMO7 | LIM domain 7 | 0.0274526 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0274419 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0273519 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0264287 |
| XPO1 | exportin 1 | 0.0262927 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0255804 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.025384 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0253612 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | 0.0253393 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0252921 |
| USP53 | ubiquitin specific peptidase 53 | 0.0252524 |
| THOC2 | THO complex 2 | 0.0251598 |
| QKI | QKI, KH domain containing, RNA binding | 0.0249904 |
| EPHA6 | EPH receptor A6 | 0.0249726 |
| ZFR | zinc finger RNA binding protein | 0.024862 |
| IL6ST | interleukin 6 signal transducer | 0.0246532 |
| AREG | amphiregulin | 0.024605 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0245027 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0243806 |
| TMEM123 | transmembrane protein 123 | 0.0243526 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0240609 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0238351 |
| NUP153 | nucleoporin 153kDa | 0.0235574 |
| TBK1 | TANK-binding kinase 1 | 0.0235009 |
| MED13L | mediator complex subunit 13-like | 0.0234805 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.023184 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 0.0231299 |
| TFG | TRK-fused gene | 0.022988 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0229019 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | 0.0227692 |
| HLTF | helicase-like transcription factor | 0.0225906 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.0224273 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0223782 |
| CLTC | clathrin, heavy chain (Hc) | 0.0222618 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0221022 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.022094 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0218974 |
| PLK2 | polo-like kinase 2 | 0.0217454 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0215134 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.021489 |
| VMP1 | vacuole membrane protein 1 | 0.0214491 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0209888 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0209568 |
| EDN1 | endothelin 1 | 0.0209114 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0207683 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0207514 |
| PNN | pinin, desmosome associated protein | 0.0206413 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0206045 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0204741 |
| DNAJC13 | DnaJ (Hsp40) homolog, subfamily C, member 13 | 0.0204015 |
| GOLT1B | golgi transport 1B | 0.0202962 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0202342 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0202143 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.195805 |
| TMSB10 | thymosin beta 10 | -0.163471 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.14954 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.145608 |
| HMGA2 | high mobility group AT-hook 2 | -0.129817 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.12066 |
| NLGN1 | neuroligin 1 | -0.114759 |
| EHBP1 | EH domain binding protein 1 | -0.0995903 |
| EGR1 | early growth response 1 | -0.0698175 |
| ACTG1 | actin gamma 1 | -0.0640576 |
| FTL | ferritin, light polypeptide | -0.0616176 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0600494 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0589266 |
| INTS6 | integrator complex subunit 6 | -0.0557287 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0537748 |
| PCDH7 | protocadherin 7 | -0.0501104 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0484607 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0474262 |
| RPL23 | ribosomal protein L23 | -0.0469473 |
| ZNF804A | zinc finger protein 804A | -0.0468505 |
| NHSL1 | NHS-like 1 | -0.0450847 |
| ADIPOR2 | adiponectin receptor 2 | -0.0447569 |
| RPS27A | ribosomal protein S27a | -0.044169 |
| ZNF638 | zinc finger protein 638 | -0.0438742 |
| CUX1 | cut-like homeobox 1 | -0.0423498 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0422245 |
| CMIP | c-Maf inducing protein | -0.0417841 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0414785 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0413362 |
| RPS19 | ribosomal protein S19 | -0.0407265 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0407127 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0385134 |
| PTMA | prothymosin, alpha | -0.038226 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0381397 |
| PCBP2 | poly(rC) binding protein 2 | -0.0380964 |
| TPI1 | triosephosphate isomerase 1 | -0.0374924 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | -0.0366073 |
| JMJD1C | jumonji domain containing 1C | -0.0357809 |
| RPLP2 | ribosomal protein, large, P2 | -0.034893 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0346425 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.034296 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0338196 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0330823 |
| YAP1 | Yes-associated protein 1 | -0.0329363 |
| UBC | ubiquitin C | -0.0325075 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0324517 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0324162 |
| R3HDM2 | R3H domain containing 2 | -0.0320319 |
| RPS8 | ribosomal protein S8 | -0.0310487 |
| LRRC23 | leucine rich repeat containing 23 | -0.030828 |
| RPL35A | ribosomal protein L35a | -0.0308094 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0307498 |
| POTEF | POTE ankyrin domain family, member F | -0.0305356 |
| RPL36 | ribosomal protein L36 | -0.0302811 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0298406 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.029792 |
| RNF213 | ring finger protein 213 | -0.0294801 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0292517 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0290525 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0289653 |
| NABP1 | nucleic acid binding protein 1 | -0.0287498 |
| EXOC4 | exocyst complex component 4 | -0.028084 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0280543 |
| TBCA | tubulin folding cofactor A | -0.0274019 |
| NEBL | nebulette | -0.0273877 |
| ANKRD12 | ankyrin repeat domain 12 | -0.027053 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0268938 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0266799 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0264494 |
| CALR | calreticulin | -0.0261815 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0260839 |
| HMGA1 | high mobility group AT-hook 1 | -0.0259465 |
| RPS3 | ribosomal protein S3 | -0.0258044 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0256935 |
| GSE1 | Gse1 coiled-coil protein | -0.0255836 |
| SETX | senataxin | -0.0255339 |
| RPS29 | ribosomal protein S29 | -0.0252779 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0251141 |
| USP34 | ubiquitin specific peptidase 34 | -0.0250279 |
| KSR2 | kinase suppressor of ras 2 | -0.0249075 |
| CANX | calnexin | -0.0247117 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.024669 |
| TUBA1B | tubulin, alpha 1b | -0.0246491 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.024431 |
| AFF4 | AF4/FMR2 family, member 4 | -0.024332 |
| ANK2 | ankyrin 2, neuronal | -0.0242758 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0241115 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0240217 |
| PRKCE | protein kinase C, epsilon | -0.0239969 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0238099 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0238052 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0237283 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0236492 |
| RPS12 | ribosomal protein S12 | -0.0234982 |
| PFN1 | profilin 1 | -0.0234189 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0233494 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | -0.0232348 |
| BPTF | bromodomain PHD finger transcription factor | -0.0230636 |
| CEP112 | centrosomal protein 112kDa | -0.0230022 |
| RPLP1 | ribosomal protein, large, P1 | -0.0229962 |
