| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (maleate) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Imiquimod (maleate)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NCOA3 | nuclear receptor coactivator 3 | 0.0696898 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0623289 |
| DTNA | dystrobrevin, alpha | 0.0602506 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.057358 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0562993 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0536752 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0521817 |
| CEP250 | centrosomal protein 250kDa | 0.051782 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.048444 |
| VMP1 | vacuole membrane protein 1 | 0.0438128 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0409979 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0407305 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0390464 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.0375378 |
| MSI2 | musashi RNA-binding protein 2 | 0.0358509 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0344442 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0330349 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.032957 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0325227 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0312388 |
| KIF16B | kinesin family member 16B | 0.0309773 |
| ANLN | anillin, actin binding protein | 0.0300842 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0291983 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 | 0.0291433 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0282032 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0278949 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0273468 |
| ENAH | enabled homolog (Drosophila) | 0.0272704 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0272657 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0269605 |
| RAD51B | RAD51 paralog B | 0.0267061 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0266946 |
| ZNF292 | zinc finger protein 292 | 0.0264155 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0262535 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0261463 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0260091 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0258178 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0255024 |
| USP53 | ubiquitin specific peptidase 53 | 0.0254618 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0249591 |
| PRELID2 | PRELI domain containing 2 | 0.024931 |
| RPL4 | ribosomal protein L4 | 0.0248967 |
| TENM2 | teneurin transmembrane protein 2 | 0.0240482 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0236928 |
| TBL1X | transducin (beta)-like 1X-linked | 0.02333 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0232415 |
| PRLR | prolactin receptor | 0.0230242 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0227618 |
| FGF13 | fibroblast growth factor 13 | 0.0226258 |
| GPC6 | glypican 6 | 0.0225348 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0222676 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0222356 |
| VCL | vinculin | 0.0220145 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0220055 |
| ATP13A3 | ATPase type 13A3 | 0.0219471 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0217696 |
| PLSCR2 | phospholipid scramblase 2 | 0.0214929 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.02133 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0212603 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0212477 |
| SPATA13 | spermatogenesis associated 13 | 0.0212387 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0211321 |
| CCNY | cyclin Y | 0.0209752 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0208398 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0206925 |
| NAA25 | N(alpha)-acetyltransferase 25, NatB auxiliary subunit | 0.0206722 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0202233 |
| CUL3 | cullin 3 | 0.020173 |
| RASA2 | RAS p21 protein activator 2 | 0.0201156 |
| POLD3 | polymerase (DNA-directed), delta 3, accessory subunit | 0.0200939 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0200445 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0199948 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0198644 |
| CCNL1 | cyclin L1 | 0.0197571 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0197161 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0195295 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0194896 |
| KAZN | kazrin, periplakin interacting protein | 0.0192265 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.0192063 |
| ECT2 | epithelial cell transforming 2 | 0.018971 |
| ZFHX3 | zinc finger homeobox 3 | 0.018869 |
| SCFD1 | sec1 family domain containing 1 | 0.018564 |
| ST8SIA6 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 | 0.0185147 |
| VCP | valosin containing protein | 0.0184443 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0184025 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.01833 |
| RCOR1 | REST corepressor 1 | 0.0183259 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.018055 |
| EXOC4 | exocyst complex component 4 | 0.0180155 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0180034 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0179815 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0179159 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.017901 |
| TPD52 | tumor protein D52 | 0.017717 |
| ADAR | adenosine deaminase, RNA-specific | 0.0177122 |
| SPAG9 | sperm associated antigen 9 | 0.0173843 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0173813 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 0.0171218 |
| PLSCR1 | phospholipid scramblase 1 | 0.017036 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0169759 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL23 | ribosomal protein L23 | -0.223836 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.174277 |
| RPL19 | ribosomal protein L19 | -0.121668 |
| ASPH | aspartate beta-hydroxylase | -0.117634 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.100856 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0979727 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0973202 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0835779 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0707367 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -0.0696793 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0681708 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0667851 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0654707 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0631409 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0627457 |
| MT2A | metallothionein 2A | -0.062318 |
| TMSB10 | thymosin beta 10 | -0.0619952 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0618314 |
| S100A8 | S100 calcium binding protein A8 | -0.0616654 |
| LASP1 | LIM and SH3 protein 1 | -0.0599093 |
| CCND1 | cyclin D1 | -0.0578964 |
| CCNI | cyclin I | -0.0573807 |
| ACTG1 | actin gamma 1 | -0.0535647 |
| MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 | -0.053407 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0530258 |
| S100A9 | S100 calcium binding protein A9 | -0.051962 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0516364 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.051061 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0503385 |
| SMYD3 | SET and MYND domain containing 3 | -0.0501618 |
| CDK12 | cyclin-dependent kinase 12 | -0.0498647 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0498167 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0478834 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.0456717 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | -0.0451617 |
| NTN4 | netrin 4 | -0.0437943 |
| GDPD1 | glycerophosphodiester phosphodiesterase domain containing 1 | -0.0434607 |
| KRT19 | keratin 19, type I | -0.0433014 |
| NCOA6 | nuclear receptor coactivator 6 | -0.0430151 |
| RPL35A | ribosomal protein L35a | -0.0425433 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0410852 |
| LDHA | lactate dehydrogenase A | -0.0410432 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | -0.0403564 |
| S100A14 | S100 calcium binding protein A14 | -0.0400299 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0398896 |
| ANXA2 | annexin A2 | -0.0393969 |
| MMP24OS | MMP24 opposite strand | -0.038521 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0384014 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0381349 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0359976 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0353174 |
| NDRG1 | N-myc downstream regulated 1 | -0.0343549 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0335748 |
| SMIM14 | small integral membrane protein 14 | -0.0334653 |
| TC2N | tandem C2 domains, nuclear | -0.0325292 |
| TMC5 | transmembrane channel-like 5 | -0.0325044 |
| SDC4 | syndecan 4 | -0.0323841 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0319927 |
| POTEF | POTE ankyrin domain family, member F | -0.0307678 |
| GATA3 | GATA binding protein 3 | -0.030452 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0304513 |
| AREG | amphiregulin | -0.030003 |
| PKM | pyruvate kinase, muscle | -0.0298339 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0298046 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0296412 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0295854 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0295165 |
| RPLP1 | ribosomal protein, large, P1 | -0.0294713 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0294001 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0293927 |
| VAV3 | vav 3 guanine nucleotide exchange factor | -0.0287402 |
| PFN1 | profilin 1 | -0.0286884 |
| EGR1 | early growth response 1 | -0.0285863 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0281725 |
| ZNF217 | zinc finger protein 217 | -0.0281036 |
| KIF5B | kinesin family member 5B | -0.0280814 |
| SEPTIN9 | septin 9 | -0.0280533 |
| FADS2 | fatty acid desaturase 2 | -0.0280087 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.027941 |
| SRCIN1 | SRC kinase signaling inhibitor 1 | -0.0278764 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0277681 |
| GNAS | GNAS complex locus | -0.027757 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0276762 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0275622 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0274994 |
| OSMR | oncostatin M receptor | -0.0273062 |
| TMEM45B | transmembrane protein 45B | -0.0273024 |
| FTL | ferritin, light polypeptide | -0.0270553 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | -0.026564 |
| TNIK | TRAF2 and NCK interacting kinase | -0.0261887 |
| FASN | fatty acid synthase | -0.0261064 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0260698 |
| RPLP0 | ribosomal protein, large, P0 | -0.0257805 |
| LMAN1 | lectin, mannose-binding, 1 | -0.025586 |
| CDH15 | cadherin 15, type 1, M-cadherin (myotubule) | -0.0255599 |
| FAT1 | FAT atypical cadherin 1 | -0.0252154 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0251822 |
| RPL8 | ribosomal protein L8 | -0.0251157 |
| S100A6 | S100 calcium binding protein A6 | -0.0250554 |
| RPS3 | ribosomal protein S3 | -0.0249392 |
