| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (maleate) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Imiquimod (maleate)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.110692 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0796963 |
| CD109 | CD109 molecule | 0.0745691 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0712119 |
| COPA | coatomer protein complex, subunit alpha | 0.0652732 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0609783 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0591321 |
| ZNF292 | zinc finger protein 292 | 0.058658 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.058571 |
| PHF21A | PHD finger protein 21A | 0.0558525 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0535594 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0528566 |
| NUP58 | nucleoporin 58 | 0.0521265 |
| NBAS | neuroblastoma amplified sequence | 0.0484442 |
| DST | dystonin | 0.0480934 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0469448 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0465975 |
| FMNL2 | formin-like 2 | 0.0464092 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0462693 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0445883 |
| TRIM2 | tripartite motif containing 2 | 0.0443798 |
| RYBP | RING1 and YY1 binding protein | 0.0441351 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0427627 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0409584 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0405648 |
| CDC73 | cell division cycle 73 | 0.0387476 |
| FBXO7 | F-box protein 7 | 0.0385328 |
| TMEM178B | transmembrane protein 178B | 0.0380657 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0378262 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0378107 |
| CALU | calumenin | 0.0365637 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0364346 |
| RNF24 | ring finger protein 24 | 0.0359843 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0358272 |
| GOLGA4 | golgin A4 | 0.034865 |
| SETD5 | SET domain containing 5 | 0.0347288 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0347094 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0335918 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0335411 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0331025 |
| RAD51B | RAD51 paralog B | 0.0317134 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0316759 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0314496 |
| NEK7 | NIMA-related kinase 7 | 0.0311244 |
| RNF145 | ring finger protein 145 | 0.0301659 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0301618 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0296646 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0292919 |
| MEF2A | myocyte enhancer factor 2A | 0.0289996 |
| FAM168A | family with sequence similarity 168, member A | 0.0284817 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.028366 |
| GTF2I | general transcription factor IIi | 0.028246 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0280322 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B | 0.027961 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0276816 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0275715 |
| MYO10 | myosin X | 0.0274871 |
| CADM1 | cell adhesion molecule 1 | 0.0274626 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0273261 |
| PTK2 | protein tyrosine kinase 2 | 0.0269028 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0266355 |
| STOM | stomatin | 0.0263678 |
| VMP1 | vacuole membrane protein 1 | 0.0263044 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0262948 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0262786 |
| AHNAK | AHNAK nucleoprotein | 0.0260383 |
| C1ORF21 | chromosome 1 open reading frame 21 | 0.0259578 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | 0.0258984 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0256617 |
| RPL3 | ribosomal protein L3 | 0.0255015 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0254592 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0252911 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0252057 |
| CUL3 | cullin 3 | 0.0250575 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0250532 |
| CALD1 | caldesmon 1 | 0.0248051 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0247995 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.0247778 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0247709 |
| FRMD6 | FERM domain containing 6 | 0.0245759 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0243465 |
| MYOF | myoferlin | 0.0241068 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0236692 |
| MREG | melanoregulin | 0.02365 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0233724 |
| RHEB | Ras homolog enriched in brain | 0.0233498 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0231019 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.023087 |
| CTBP2 | C-terminal binding protein 2 | 0.0229536 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0228616 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0227455 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0226809 |
| RNF150 | ring finger protein 150 | 0.0225427 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0225359 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0224121 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0223883 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0221518 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0220332 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.022019 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0218414 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.276854 |
| VIM | vimentin | -0.207884 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.107581 |
| MT2A | metallothionein 2A | -0.104018 |
| FN1 | fibronectin 1 | -0.100253 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.084783 |
| TMSB10 | thymosin beta 10 | -0.084333 |
| TNNC1 | troponin C type 1 (slow) | -0.0781819 |
| LOC112694756 | uncharaterized LOC112694756 | -0.067782 |
| RPLP1 | ribosomal protein, large, P1 | -0.0590959 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0521241 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0490596 |
| OSMR | oncostatin M receptor | -0.0468395 |
| EGR1 | early growth response 1 | -0.0442937 |
| IER3 | immediate early response 3 | -0.0440226 |
| HLA-B | major histocompatibility complex, class I, B | -0.0425263 |
| NAV2 | neuron navigator 2 | -0.0414138 |
| VGF | VGF nerve growth factor inducible | -0.0403738 |
| ACTG1 | actin gamma 1 | -0.0402394 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0397322 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0396027 |
| CENPF | centromere protein F, 350/400kDa | -0.0383019 |
| RPL35A | ribosomal protein L35a | -0.0379707 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0365991 |
| MT1X | metallothionein 1X | -0.0359466 |
| RPL37A | ribosomal protein L37a | -0.0354699 |
| S100A6 | S100 calcium binding protein A6 | -0.0353692 |
| GPC6 | glypican 6 | -0.033162 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0331496 |
| RPS8 | ribosomal protein S8 | -0.033138 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0322173 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0307723 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0292642 |
| RPS24 | ribosomal protein S24 | -0.02809 |
| GNAS | GNAS complex locus | -0.0278998 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0272817 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0270033 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0268293 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0267233 |
| CD63 | CD63 molecule | -0.0265361 |
| RPL30 | ribosomal protein L30 | -0.0262656 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0260978 |
| RPL23 | ribosomal protein L23 | -0.025923 |
| FMN1 | formin 1 | -0.0255868 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0254189 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0253118 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0252548 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.025158 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0250693 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0250557 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0246466 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0232658 |
| A2M | alpha-2-macroglobulin | -0.0231586 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0228021 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0227936 |
| NLGN1 | neuroligin 1 | -0.0227909 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0224785 |
| OXR1 | oxidation resistance 1 | -0.0222319 |
| RPLP2 | ribosomal protein, large, P2 | -0.0221687 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0219307 |
| FUS | FUS RNA binding protein | -0.0219245 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.021559 |
| RPS20 | ribosomal protein S20 | -0.02142 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0214001 |
| RPL34 | ribosomal protein L34 | -0.021208 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0210415 |
| PARD3B | par-3 family cell polarity regulator beta | -0.021031 |
| TAGLN2 | transgelin 2 | -0.0210218 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0209557 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0208297 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0208276 |
| PCNX1 | pecanex 1 | -0.0207538 |
| RACK1 | receptor for activated C kinase 1 | -0.0207388 |
| LDHA | lactate dehydrogenase A | -0.0206579 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0206242 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0205991 |
| DENND1A | DENN/MADD domain containing 1A | -0.0205725 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0203775 |
| PLOD3 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 | -0.0202701 |
| NDRG1 | N-myc downstream regulated 1 | -0.0202309 |
| RPS19 | ribosomal protein S19 | -0.020225 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0201335 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.0199912 |
| S100A9 | S100 calcium binding protein A9 | -0.0199589 |
| RCAN1 | regulator of calcineurin 1 | -0.0197847 |
| RPLP0 | ribosomal protein, large, P0 | -0.0196232 |
| PCDH7 | protocadherin 7 | -0.0196126 |
| RPL19 | ribosomal protein L19 | -0.0192568 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0192388 |
| FTL | ferritin, light polypeptide | -0.0188566 |
| PTCHD4 | patched domain containing 4 | -0.0188404 |
| RPL31 | ribosomal protein L31 | -0.0187285 |
| LMNA | lamin A/C | -0.0187247 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0186433 |
| RPS27A | ribosomal protein S27a | -0.0184901 |
| GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | -0.0184803 |
| TRIB1 | tribbles pseudokinase 1 | -0.0183721 |
| RHOJ | ras homolog family member J | -0.0183019 |
| PAX3 | paired box 3 | -0.018261 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | -0.0179517 |
