| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (maleate) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Imiquimod (maleate)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.117873 |
| TSC22D2 | TSC22 domain family, member 2 | 0.100947 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0966286 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0869876 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0824967 |
| FAM13A | family with sequence similarity 13, member A | 0.0812478 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0762661 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0700538 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0695637 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0695424 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0616821 |
| CCNY | cyclin Y | 0.057551 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0574195 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0571855 |
| TOP1 | topoisomerase (DNA) I | 0.0564878 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0534734 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0533508 |
| TFG | TRK-fused gene | 0.0501544 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0497582 |
| NUP58 | nucleoporin 58 | 0.049512 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0479054 |
| SPAG9 | sperm associated antigen 9 | 0.0474361 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0472078 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0470528 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0465577 |
| USP3 | ubiquitin specific peptidase 3 | 0.0447732 |
| RPL4 | ribosomal protein L4 | 0.04421 |
| HELZ | helicase with zinc finger | 0.0435338 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0430716 |
| CDC73 | cell division cycle 73 | 0.0429365 |
| APP | amyloid beta (A4) precursor protein | 0.0419804 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0417272 |
| SLMAP | sarcolemma associated protein | 0.0394407 |
| ZNF292 | zinc finger protein 292 | 0.0389949 |
| OGA | O-GlcNAcase | 0.0384993 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0379689 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0373597 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0373473 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0370817 |
| ATP13A3 | ATPase type 13A3 | 0.0370655 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0364203 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0363059 |
| TPM3 | tropomyosin 3 | 0.0362445 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0361556 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0356217 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0354149 |
| MATR3 | matrin 3 | 0.035302 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.03462 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0343668 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0341197 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0340985 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0340467 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0337888 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0337391 |
| RBM39 | RNA binding motif protein 39 | 0.0331456 |
| RLF | rearranged L-myc fusion | 0.0330638 |
| PGK1 | phosphoglycerate kinase 1 | 0.0328626 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0316472 |
| QKI | QKI, KH domain containing, RNA binding | 0.0314526 |
| RTN4 | reticulon 4 | 0.0312079 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0310344 |
| FAM162A | family with sequence similarity 162, member A | 0.0310056 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0302896 |
| HPCAL1 | hippocalcin-like 1 | 0.0302617 |
| CCNL1 | cyclin L1 | 0.0301958 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0301574 |
| RASA2 | RAS p21 protein activator 2 | 0.0301518 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0294592 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0294072 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0293862 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0292986 |
| PLAU | plasminogen activator, urokinase | 0.0291231 |
| NCKAP1 | NCK-associated protein 1 | 0.0290723 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0290047 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0288686 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0288615 |
| OLA1 | Obg-like ATPase 1 | 0.0288543 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0285227 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0285097 |
| YTHDC1 | YTH domain containing 1 | 0.0282523 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | 0.0282303 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0281905 |
| PNN | pinin, desmosome associated protein | 0.0279208 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0275908 |
| MYO1B | myosin IB | 0.0275627 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.027512 |
| YBX1 | Y box binding protein 1 | 0.0274639 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0273409 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0270376 |
| DDX52 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 | 0.0266912 |
| SUCO | SUN domain containing ossification factor | 0.0266718 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0263103 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0258928 |
| ABI1 | abl-interactor 1 | 0.0257113 |
| NEK7 | NIMA-related kinase 7 | 0.0256265 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0255355 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | 0.0252277 |
| CASC3 | cancer susceptibility candidate 3 | 0.0252157 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0252019 |
| KRT8 | keratin 8, type II | 0.0251028 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.177231 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.175253 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.173027 |
| TMSB10 | thymosin beta 10 | -0.148364 |
| CP | ceruloplasmin (ferroxidase) | -0.114333 |
| HLA-B | major histocompatibility complex, class I, B | -0.111677 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.100799 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0937071 |
| MMP7 | matrix metallopeptidase 7 | -0.0915368 |
| B2M | beta-2-microglobulin | -0.0883672 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.087324 |
| KRT19 | keratin 19, type I | -0.0864939 |
| FTL | ferritin, light polypeptide | -0.0853319 |
| MT1X | metallothionein 1X | -0.0839066 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0802952 |
| APOL1 | apolipoprotein L, 1 | -0.0702026 |
| NDRG1 | N-myc downstream regulated 1 | -0.064554 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0620059 |
| VIM | vimentin | -0.0607096 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.057646 |
| EFNA5 | ephrin-A5 | -0.0539169 |
| RNF213 | ring finger protein 213 | -0.0535258 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.051728 |
| S100A6 | S100 calcium binding protein A6 | -0.0509039 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0502244 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0501708 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0494152 |
| CSTB | cystatin B (stefin B) | -0.0492309 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.048981 |
| RPL23 | ribosomal protein L23 | -0.0480704 |
| MX1 | MX dynamin-like GTPase 1 | -0.0475099 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0467078 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0423565 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0423439 |
| RPL35A | ribosomal protein L35a | -0.0419253 |
| EGR1 | early growth response 1 | -0.0418451 |
| HMGA1 | high mobility group AT-hook 1 | -0.0415659 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0410821 |
| MX2 | MX dynamin-like GTPase 2 | -0.0400954 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0399766 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.039458 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0387843 |
| SP100 | SP100 nuclear antigen | -0.0387684 |
| LCN2 | lipocalin 2 | -0.0383299 |
| MYO1E | myosin IE | -0.0382188 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0381431 |
| RAD51B | RAD51 paralog B | -0.037719 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0376892 |
| JUP | junction plakoglobin | -0.0371331 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0368337 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0356175 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0355345 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0354288 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0353472 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0351999 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.035093 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0348349 |
| S100A10 | S100 calcium binding protein A10 | -0.0347977 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0343015 |
| RPS29 | ribosomal protein S29 | -0.0340124 |
| HLA-A | major histocompatibility complex, class I, A | -0.0337471 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0323463 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0322864 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.032213 |
| EHBP1 | EH domain binding protein 1 | -0.0321801 |
| NABP1 | nucleic acid binding protein 1 | -0.0321418 |
| ANXA4 | annexin A4 | -0.0319188 |
| RPLP1 | ribosomal protein, large, P1 | -0.031917 |
| LMO7 | LIM domain 7 | -0.0316811 |
| RPS8 | ribosomal protein S8 | -0.0313336 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.031073 |
| RPL34 | ribosomal protein L34 | -0.030956 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0305021 |
| S100A11 | S100 calcium binding protein A11 | -0.0302353 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0300266 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0297368 |
| ST8SIA6 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 | -0.0294068 |
| MUC4 | mucin 4, cell surface associated | -0.02932 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0289822 |
| PMP22 | peripheral myelin protein 22 | -0.0287081 |
| TMC5 | transmembrane channel-like 5 | -0.0284873 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0282558 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0282456 |
| RPS19 | ribosomal protein S19 | -0.0281702 |
| PARD3 | par-3 family cell polarity regulator | -0.0279514 |
| TXNIP | thioredoxin interacting protein | -0.0276885 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.027546 |
| NRG3 | neuregulin 3 | -0.0274143 |
| OSMR | oncostatin M receptor | -0.0273453 |
| PCDH7 | protocadherin 7 | -0.0272936 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0272278 |
| CMIP | c-Maf inducing protein | -0.0271822 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0271713 |
| BPTF | bromodomain PHD finger transcription factor | -0.0270914 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0269801 |
| MUC1 | mucin 1, cell surface associated | -0.0269181 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0268606 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0268222 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0262951 |
| MUC16 | mucin 16, cell surface associated | -0.0262559 |
